LOCUS       XM_047432856            3254 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens mitogen-activated protein kinase kinase 5
            (MAP2K5), transcript variant X5, mRNA.
ACCESSION   XM_047432856
VERSION     XM_047432856.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3254
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..3254
                     /gene="MAP2K5"
                     /gene_synonym="HsT17454; MAPKK5; MEK5; PRKMK5"
                     /note="mitogen-activated protein kinase kinase 5; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 5 ESTs, 79 long SRA reads, and 99% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 5 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:5607"
                     /db_xref="HGNC:HGNC:6845"
                     /db_xref="MIM:602520"
     CDS             88..831
                     /gene="MAP2K5"
                     /gene_synonym="HsT17454; MAPKK5; MEK5; PRKMK5"
                     /codon_start=1
                     /product="dual specificity mitogen-activated protein
                     kinase kinase 5 isoform X4"
                     /protein_id="XP_047288812.1"
                     /db_xref="GeneID:5607"
                     /db_xref="HGNC:HGNC:6845"
                     /db_xref="MIM:602520"
                     /translation="MMEGHFPQSDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKA
                     MLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSD
                     SLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKV
                     ILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRK
                     MPEHVLGRIAVAVVKGLTYLWSLKILHRG"
     polyA_site      3254
                     /gene="MAP2K5"
                     /gene_synonym="HsT17454; MAPKK5; MEK5; PRKMK5"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gccagttctg ctgcagcctg ggagggacac tgtggcagag ctcctggaga gaaatgaggt
       61 ttgcaggcca ttggagttgg actggacatg atggagggtc actttcccca gagcgatgtg
      121 ataggccagg ttctgcctga agcaacaact acagcatttg aatatgaaga tgaagatggt
      181 gatcgaatta cagtgagaag tgatgaggaa atgaaggcaa tgctgtcata ttattattcc
      241 acagtaatgg aacagcaagt aaatggacag ttaatagagc ctctgcagat atttccaaga
      301 gcctgcaagc ctcctgggga acggaacata catggcctga aggtgaatac tcgggccgga
      361 ccctctcaac acagcagccc agcagtctca gattcacttc caagcaatag cttaaagaag
      421 tcttctgctg aactgaaaaa aatactagcc aatggccaga tgaatgaaca agacatacga
      481 tatcgggaca ctcttggtca tggcaacgga ggcacagtct acaaagcata tcatgtcccg
      541 agtgggaaaa tattagctgt aaaggtcata ctactagata ttacactgga acttcagaag
      601 caaattatgt ctgaattgga aattctttat aagtgcgatt catcatatat cattggattt
      661 tatggagcat tttttgtaga aaacaggatt tcaatatgta cagaattcat ggatggggga
      721 tctttggatg tatataggaa aatgccagaa catgtccttg gaagaattgc agtagcagtt
      781 gttaaaggcc ttacttattt gtggagttta aagattttac atagagggta agagagtgac
      841 cacagtgacc acaaaagcac ctgcagaaac tatggattat caatttattt attagtaatt
      901 agtcatggta atgagaaatc aagttgtgtt ttgaggttga ttttttaaaa cagctttatt
      961 gatatataat ttgcatgcca taaaattcat ctactcaatt cagtgatttt tagtaagttt
     1021 ataaagttgt gcaaccataa ccataatcca gttttagaac attttcatca ccccaaaaaa
     1081 gtgtcctcat gttcattggc aatcactccc tgctcctgtc ctcagcccca gggaaccact
     1141 gatttacttt ctgactttta cagatttgcc ttttctggac attttatata agcagaaaca
     1201 taccacatga aatctttgtg cctgacttct ttcacttagc atgatgtttt tgagatgtgt
     1261 ctgtattata gcatgtgtct atagttcatt cctttttatt gttgaatagt attccattgt
     1321 atggatatat cacattttgt ctgcttattt actagtagag ggatatttgg cattgtatcc
     1381 actttgggac gattatgaat aatactactt ttcatacaca agtctttatg tggttctgta
     1441 ttttcatttc tcttgagtaa atacctagga gtggaattgg tatatttctt tagatatttg
     1501 taaatcatag tttatcaggc catctagcac atatcagatt tgagaagaaa taattatttt
     1561 accattggta tatattatat gattagtata atgaaccaat gtttcatact ttgttaaaga
     1621 gtgaccacat agtgactaca aaggtcatat gatagcttta tgtttaagtt ttaaagacac
     1681 tttgaggctg atttttattt acctaaaacc acctactatt atccttagca tgacagaagg
     1741 ctcttttagt aaactcttcc attctttctg ctcactgata tttttctaat aatcttctaa
     1801 gcatttcaag ttattggatg gaactgcatc ataaccacct attatctact tgggctgtca
     1861 ctgctgcaac tcaaagattt attgcatcat cgttaaaaag cccagcttac tgtgaaatct
     1921 cactgaagga gtgagacagt attgtgacag gagacacatg ttgtgattgg ataatgttaa
     1981 ctcgtctgtg atcccagctg aacacacttg ctaccctaga agaagcctgc cttcaggtgg
     2041 agctggtata atgaaagtta acctcattta gcatttggat atgagccaat gtattaaatg
     2101 atccacatcc tgatttccta gagtggaagt catcattact gattctacaa agcagtagct
     2161 ttatagtata tttggtacat tcaagtttac aaaatgtttt tcccattcat ctgattcatt
     2221 caacatttca ctgacctcta gctctgtgcc agcagtgcta agcacacagg cccacttcat
     2281 tctcttaaca gccttgtcaa tgtaggaaga tcagatatca agatatcaga tatcaggata
     2341 tcatatacag gatatgatgt acaagatcag ggatgatatc tgatcttcca acactggcaa
     2401 ggttgtcagt gagaattcag gattgttatg agaattaagt gaaattgtgt gctcaacact
     2461 gagcatgtga gtgttgtgag tacacacacc cacacgtaca tgtatgctca gagaggttta
     2521 aatgattcgt ccagtctcac agtcagtatg cagcggcacc ttccagggca tcactctgct
     2581 tcctttaagg gaatctgacc cacaggaatc tattttgatg cctataaaag cctactgcat
     2641 aaaatgacta aatcttttaa aatgaaaaaa ggagtattgg atattaaaaa tgagccactt
     2701 tacattgtgc ctttatctta ctatttccaa aatgatagtc atctcttggc caagatagct
     2761 taaacccaaa ccttaaatta ggaaacacct aaacttgata tttttaatgc aaaaggagaa
     2821 taagttagtt tgctttttca ctaaaggttt atgtgttgcg gtagaagaaa cttatttctc
     2881 tttagtggta tgaaaaggac ccataattcc aggcttcaac acacctcatt tgtattttct
     2941 ttgagaaaat gtctcagtta aaatcaatgc cctagtattc atttgagctc ccttgccttc
     3001 aataaaacta attgataaac cctaataatt aatgccctga ttaaaccaaa atgacttaca
     3061 tctgccctga tgattgccat ttataatcaa tcactttaat gactcatctt ttctgtgctt
     3121 tgcttacaga agaaaggctg tgatgttttt aagtgaactg aatgaaaagc tgtatgcctt
     3181 caattgctgt ttgttttcca taacttgata ttgcattaaa ataagcataa atataactac
     3241 ctccttaaaa gtaa
//
