LOCUS       NM_001085481             818 bp    mRNA    linear   PRI 16-FEB-2025
DEFINITION  Homo sapiens microtubule associated protein 1 light chain 3 beta 2
            (MAP1LC3B2), mRNA.
ACCESSION   NM_001085481 XM_926608 XM_941645
VERSION     NM_001085481.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 818)
  AUTHORS   Trevino,L.R., Yang,W., French,D., Hunger,S.P., Carroll,W.L.,
            Devidas,M., Willman,C., Neale,G., Downing,J., Raimondi,S.C.,
            Pui,C.H., Evans,W.E. and Relling,M.V.
  TITLE     Germline genomic variants associated with childhood acute
            lymphoblastic leukemia
  JOURNAL   Nat Genet 41 (9), 1001-1005 (2009)
   PUBMED   19684603
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DN994744.1, AC125603.7, AI719464.1 and AI540365.1.
            
            On May 17, 2019 this sequence version replaced NM_001085481.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DN994744.1, SRR3476690.923589.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145893, SAMEA2157437
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000556529.4/ ENSP00000450524.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-136               DN994744.1         8-143
            137-137             AC125603.7         10801-10801
            138-660             DN994744.1         145-667
            661-806             AI719464.1         1-146               c
            807-809             AI540365.1         1-3                 c
            810-818             AC125603.7         11474-11482
FEATURES             Location/Qualifiers
     source          1..818
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.22"
     gene            1..818
                     /gene="MAP1LC3B2"
                     /gene_synonym="ATG8G"
                     /note="microtubule associated protein 1 light chain 3 beta
                     2"
                     /db_xref="GeneID:643246"
                     /db_xref="HGNC:HGNC:34390"
                     /db_xref="MIM:620673"
     exon            1..53
                     /gene="MAP1LC3B2"
                     /gene_synonym="ATG8G"
                     /inference="alignment:Splign:2.1.0"
     exon            54..818
                     /gene="MAP1LC3B2"
                     /gene_synonym="ATG8G"
                     /inference="alignment:Splign:2.1.0"
     CDS             155..532
                     /gene="MAP1LC3B2"
                     /gene_synonym="ATG8G"
                     /note="microtubule-associated proteins 1A/1B light chain 3
                     beta 2; Microtubule-associated proteins 1A/1B light chain
                     3B-like protein; MAP1A/MAP1B LC3 B-like; MAP1A/MAP1B light
                     chain 3 B-like"
                     /codon_start=1
                     /product="microtubule-associated protein 1 light chain 3
                     beta 2"
                     /protein_id="NP_001078950.1"
                     /db_xref="CCDS:CCDS41841.1"
                     /db_xref="GeneID:643246"
                     /db_xref="HGNC:HGNC:34390"
                     /db_xref="MIM:620673"
                     /translation="MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQL
                     PVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESE
                     KDEDGFLYMVCASQETFGMKLSV"
ORIGIN      
        1 gcaaggctcg cagccacctc tcgggagtgc agggccagat cctgtgccag cggccttaca
       61 cggccacagt cggattcgct gccgcagcag ccgccacccc caggagccgc cgggaccctc
      121 gcgtcgtcgc cgccgcggcc cagatcccca caccatgccg tcggagaaga ccttcaagca
      181 gcggcgcacc ttcgaacaaa gagtagaaga tgtccgactt attcgagagc agcatccaac
      241 caaaatcccg gtgataatag aacgatacaa gggtgagaag cagcttcctg ttctggataa
      301 aacaaagttc cttgtacctg accatgtcaa catgagtgag ctcatcaaga taattagaag
      361 gcgcttacag ctcaatgcta atcaggcctt cttcctgttg gtgaacggac acagcatggt
      421 cagcgtctcc acaccaatct cagaggtgta tgagagtgag aaagatgaag atggattcct
      481 gtacatggtc tgtgcctccc aggagacgtt cgggatgaaa ttgtcagtgt aaaaccagaa
      541 aaaatgcatc tcttctagaa ttttttaaac ccttaccaag gaaaaaaaaa gggatgttac
      601 caactgagat cgatcagttc atctaatcac agatcatcaa acagtagtgt tcccacctag
      661 gagtgttagg aagttgtgtt tgtgtttcaa gcagaaaaac tgagctccaa gtgagcacat
      721 tcagctttgg aaactatatt atttaatgta ggctagcttg ttttcaaatt ttaaaagttt
      781 aaaaataaaa tactttgcat tctaaaaaaa aaaaaaaa
//
