LOCUS       NM_019090               4514 bp    mRNA    linear   PRI 04-AUG-2024
DEFINITION  Homo sapiens microtubule associated protein 10 (MAP10), mRNA.
ACCESSION   NM_019090 XM_378184 XM_939257
VERSION     NM_019090.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4514)
  AUTHORS   Fong,K.W., Leung,J.W., Li,Y., Wang,W., Feng,L., Ma,W., Liu,D.,
            Songyang,Z. and Chen,J.
  TITLE     MTR120/KIAA1383, a novel microtubule-associated protein, promotes
            microtubule stability and ensures cytokinesis
  JOURNAL   J Cell Sci 126 (Pt 3), 825-837 (2013)
   PUBMED   23264731
  REMARK    GeneRIF: these data suggest that MTR120 is a novel microtubule
            (MT)-associated protein that directly stabilizes MTs and hence
            ensures the fidelity of cell division.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL451083.5.
            
            On Jul 22, 2020 this sequence version replaced NM_019090.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB037804.1, BC036663.2 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000418460.4/ ENSP00000403208.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4514              AL451083.5         40236-44749
FEATURES             Location/Qualifiers
     source          1..4514
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q42.2"
     gene            1..4514
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
                     /note="microtubule associated protein 10"
                     /db_xref="GeneID:54627"
                     /db_xref="HGNC:HGNC:29265"
                     /db_xref="MIM:618551"
     exon            1..4514
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..2752
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
                     /note="microtubule regulator 120 KDa; microtubule
                     regulator of 120 KDa"
                     /codon_start=1
                     /product="microtubule-associated protein 10"
                     /protein_id="NP_061963.3"
                     /db_xref="CCDS:CCDS44334.2"
                     /db_xref="GeneID:54627"
                     /db_xref="HGNC:HGNC:29265"
                     /db_xref="MIM:618551"
                     /translation="MAASLSERLFSLELLVDWVRLEARLLPSPAAAVEQEEEEEEKEQ
                     GEASSPRGLCPAVAFRLLDFPTLLVYPPDGPGAPAAEPWPGVIRFGRGKSCLFRLQPA
                     TLHCRLLRTPLATLLLQLPPGRPTPTPQLLGACDISLATAAHRVVGPAASGCSHRHRG
                     RFPLHNRVGERTGDIALAYRLTDLGSRLLSQLERPLTFTRTGGGAEVSPQTQQERQQL
                     QQPASQPSPKEADKPLGELEIPEAQKDLKEMVKSKAECDNVGSVENGKTNSVVTCSGA
                     GNGRNVSSLNEEVTELDMETNIFCPPPLYYTNLTQEKPPPAQAKITIEPQMNAPEEMD
                     DASPEKKRVNPPAHRSCLKHPSSAAHEHPPMLVNPPHIQNIGATNQTCQTEQNRINTI
                     RQLPLLNALLVELSLLYDQPVTSPAHIHPHLAWLYRTEDKKSPESSAKSTCRSEAKKD
                     KRSVGGCEKSVSLQYKKNQIENYKEDKYSEKSSGALHKRVPKGRLLYGLTNTLRLRLK
                     LTNPDMLVVHEKRELYRKRQSQMLGTKFRIPSSKVKLLSSAEQSQKPQLPEDKYLDSD
                     ASFTENSDTSRQISGVFDEPSTSKETKLKYATEKKTVDCSKNRINNVSLEEVVSPANS
                     IIPERLTPTNILGGNVEMKIQSPCVFQQDAVVDRIVDKEIDIRQVKTTDNDILMADIS
                     DKRTGKNSCYENISELKYSDDLSSPCYSEDFCTSEDTSRSFKAHDSSSRTENPKHSQY
                     TSKSSDTGVSKKKNSSDRSSILSPPFSAGSPVHSYRKFHISKTQDKSLEEASSISASD
                     LSSTHWTEQKENQIDQNSMHNSEITKRAQDISVKTRSSWKSLEKSQSPQTSQVSSYLP
                     SNVSELNVLDSSTSDHFEEGNDDVGSLNISKQCKDICELVINKLPGYTM"
     regulatory      2971..2976
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
                     /note="hexamer: AATAAA"
     polyA_site      2992
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
                     /note="major polyA site"
     regulatory      3331..3336
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
                     /note="hexamer: ATTAAA"
     polyA_site      3353
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
     regulatory      3440..3445
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
                     /note="hexamer: AATAAA"
     polyA_site      3463
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
     regulatory      4490..4495
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
                     /note="hexamer: AATAAA"
     regulatory      4496..4501
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
                     /note="hexamer: AATATA"
     polyA_site      4508
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
     polyA_site      4514
                     /gene="MAP10"
                     /gene_synonym="KIAA1383; MTR120"
ORIGIN      
        1 ggagcccgcg gcggcgtttc ctggggcaac agcaatggcg gcctcgctgt ccgagcggct
       61 cttctcgctg gagctgctgg tggactgggt gcgtttggaa gcccggctgc tgccgtcccc
      121 cgctgccgca gtggagcagg aggaggaaga ggaggaaaag gagcaggggg aggcctcgtc
      181 gccgcgcggt ctgtgccccg ccgtggcctt ccgcctgctg gacttcccca cgctgttggt
      241 ttaccctcct gacggccccg gcgctcccgc cgccgaaccg tggcccggtg tcatccgctt
      301 cggtcgcggc aagtcctgcc tcttccgcct gcagcctgct accctgcact gccggctcct
      361 gcggaccccg cttgccacct tgctgctgca gctgccccct gggcgcccga cgcccacccc
      421 acagctcctg ggggcctgcg acatttcgct ggccaccgca gcgcacaggg tcgtggggcc
      481 ggccgcctcc ggatgctccc accgtcaccg gggacgtttc cccctgcata atcgagtggg
      541 cgagcggact ggggacattg cactggccta ccgcctgact gacctgggaa gccgcctgct
      601 gagccaactt gagcggcccc tcaccttcac ccgcacagga ggaggagcgg aggtcagtcc
      661 ccaaacccag caggaaagac agcagctgca gcagccagcc tcacagccaa gcccaaaaga
      721 ggctgataag ccgctggggg agttagaaat cccagaggca cagaaggatt tgaaggaaat
      781 ggttaaaagt aaggccgaat gtgataatgt gggttctgtg gagaatggca aaaccaattc
      841 tgttgttaca tgttcaggtg ctggcaatgg gagaaatgtt agctccctaa atgaggaagt
      901 cacagaattg gacatggaga ccaatatatt ttgccctcct cctttgtatt acactaactt
      961 gacccaagaa aaaccgcccc ctgcacaggc taaaatcacc attgagcctc aaatgaatgc
     1021 acctgaggaa atggatgatg cttctcctga aaaaaagcgt gtaaatcccc cagcacacag
     1081 gagttgtcta aagcatccaa gttctgcagc acacgaacat cctccaatgc ttgtaaatcc
     1141 tccacatatt cagaatatag gagcaactaa tcaaacatgt caaactgaac aaaatcgaat
     1201 taatacaata aggcagttgc ctttgttaaa tgctttgtta gttgagttgt ccttgttata
     1261 tgaccaacct gtgacaagtc ctgctcatat acatcctcac ctagcctggt tatataggac
     1321 tgaggataag aagtcacccg aatcttctgc caaatccaca tgccggtctg aagccaagaa
     1381 ggataagcgt tctgtggggg gatgtgaaaa gtcagtgagt cttcagtata aaaagaacca
     1441 aattgaaaac tataaggaag ataaatattc tgaaaagagc agtggtgccc tccataaaag
     1501 agttccaaaa gggaggctac tttatggctt aacaaataca ctaagactac gtttaaagct
     1561 gacaaatcct gatatgttgg tggtacatga aaaaagagaa ctatatagaa aaagacaatc
     1621 acaaatgttg ggtacaaaat tcagaattcc gtcatccaaa gttaaactat taagctctgc
     1681 agaacaaagt cagaagccac aactgcctga agataagtat ttagattcag atgcatcttt
     1741 cactgaaaat agtgatacct caagacaaat cagtggagtt tttgatgagc ccagcacaag
     1801 taaagaaact aaactgaaat atgcaactga aaaaaagaca gttgattgta gtaaaaatag
     1861 aatcaataat gtttcattgg aagaagttgt gagtcctgca aattccatta ttccagaaag
     1921 gcttacccct acaaatattc tgggaggaaa tgtggaaatg aaaatccaaa gtccatgtgt
     1981 tttccaacag gatgctgttg ttgacagaat tgtagataag gaaatagata ttagacaggt
     2041 caaaaccaca gataatgaca ttcttatggc tgatataagt gacaagagaa caggtaaaaa
     2101 tagttgctat gaaaacatct cagaactgaa gtattcagat gatttgtcta gcccttgcta
     2161 ttctgaagat ttctgtacca gtgaggacac cagcagaagt ttcaaagctc atgatagcag
     2221 ttcaaggaca gaaaatccaa aacatagtca atatacaagc aagtctagtg acacaggagt
     2281 gtccaaaaag aaaaatagta gtgacaggag ttctatcctt agcccacctt tttcagccgg
     2341 gtcacctgta cactcataca gaaaatttca tatttcaaag actcaggata aaagtttgga
     2401 ggaagcatct agtatctctg ctagtgattt atcttcaaca cattggactg aacaaaaaga
     2461 aaaccagata gatcaaaata gtatgcacaa ttctgaaatt acaaagagag ctcaagacat
     2521 ctctgttaaa acaagaagta gttggaaatc tttagaaaaa agccagtcac cacaaacatc
     2581 ccaggtgagt tcttacctgc cttcaaatgt gtccgaactt aatgtcctgg atagcagtac
     2641 atcagatcac tttgaagaag gcaatgatga tgttggttca ctaaatattt ccaagcaatg
     2701 caaagatatt tgtgaattag taataaataa acttccagga tacacaatgt aaaaatacat
     2761 gcttttaaaa aactttcaag gacctatgtg tactgttagt gaaaaaaatt ttaaagctgt
     2821 tttagttcat gaattatgtg aataattttt taaagaaata tgaattaacg ttattccttt
     2881 gatgtttaaa tggtatttta ccattaaatc tgataatatt gattattaaa tcatataaac
     2941 agatttcttt ttaaattgtt taatcataag aataaaagtg tgtctttcta aattgtctct
     3001 cttaaagtgt ctagtctaca gtattgatca ttctaaagct gacttcatgc acaccactga
     3061 aaaagaaggc tagttagtaa ggacagcctc aaattttaat tggaacaaat tatttaacaa
     3121 atatagaaga cttactgtgt tagatgcaga aaggtgcaga atctatttat gatagagccc
     3181 tgctgtttta aaagcttaca gttgtatgta gataagaagt cttccttgac atatacatat
     3241 cccatatccc caataggtga agttgctttt atatgctctc atagtgccct gcaccttttg
     3301 tttataagcc acaatttgtg tgattacttg attaaagttt atcttccact aggcttcagt
     3361 tgtgtgatgg gatcatattt gttttacaca tcagtgcatt tttgtatcta gcacaattcc
     3421 tggcatgtgg ctgcagtgca ataaaaacat ttgttgaaaa aaacgaagcc caggcattta
     3481 aaatacctaa tgggagggtt tagaattaag cagcaaaaat aagcagattc cctaaaataa
     3541 acctgcagaa aatccttatt ggaaatatat ttgactgtaa tatttctgtt ttgcttggta
     3601 taaatagcct tcaggtgttc tctgaaatat ttggaaaggg aaacttaaga aggtatcttt
     3661 tatacagttt ctgatatagg agttcagttt cttgtcattt cagtttgttc aatggttatt
     3721 tttagtgtat ggaactttgt ttttatgaaa tccagtgata atttataatt tattccattg
     3781 gttttatatt tagactttat tctgtgttca aatatttaca tatattttct tctagctgtg
     3841 ttatacttta atttttagac tttttaatat atctaacgtt tttgaatgta tgaagtgagg
     3901 ttctaatttc ctttctttaa aggtaattaa ttatataggt attctgaatg atcataatac
     3961 tagaatatag atagatggta aaaagagaga agaggatgtt acattttggg gagcaatatg
     4021 aataaaagag tgatgggaat gagcctgata tatttatggg acaatttaaa atattatctt
     4081 gaatagaatg atccactcat gctacagagt ggtagaaagg acatttgttg agtaaggaaa
     4141 atgccagatt acagagagcc tcaaatgcta agtataataa tagaattcta agcaatagga
     4201 ataacagatt attttaggtt ataaatgagc actagtaagt agtcatgaca ttttgaatat
     4261 tttaaattat tgaaaataat aagcagagaa attatatcag ttaaagtttt gagatatgaa
     4321 aggtttctgt ggctagtggc tatgatctta atttttctaa aatataaagc atatagtata
     4381 acatttcaca aaatcaaaat attgtaatgc caggtattgt aactagatgt ttaatgatgt
     4441 gaactgtgta aattgtttaa tagcaatttg tcattactat ggaagagaca ataaaaatat
     4501 aagcaatatc agaa
//
