LOCUS       NM_001146221            1667 bp    mRNA    linear   PRI 15-FEB-2024
DEFINITION  Homo sapiens MANSC domain containing 4 (MANSC4), mRNA.
ACCESSION   NM_001146221 XM_001724850
VERSION     NM_001146221.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1667)
  AUTHORS   Scherer,S.E., Muzny,D.M., Buhay,C.J., Chen,R., Cree,A., Ding,Y.,
            Dugan-Rocha,S., Gill,R., Gunaratne,P., Harris,R.A., Hawes,A.C.,
            Hernandez,J., Hodgson,A.V., Hume,J., Jackson,A., Khan,Z.M.,
            Kovar-Smith,C., Lewis,L.R., Lozado,R.J., Metzker,M.L.,
            Milosavljevic,A., Miner,G.R., Montgomery,K.T., Morgan,M.B.,
            Nazareth,L.V., Scott,G., Sodergren,E., Song,X.Z., Steffen,D.,
            Lovering,R.C., Wheeler,D.A., Worley,K.C., Yuan,Y., Zhang,Z.,
            Adams,C.Q., Ansari-Lari,M.A., Ayele,M., Brown,M.J., Chen,G.,
            Chen,Z., Clerc-Blankenburg,K.P., Davis,C., Delgado,O., Dinh,H.H.,
            Draper,H., Gonzalez-Garay,M.L., Havlak,P., Jackson,L.R.,
            Jacob,L.S., Kelly,S.H., Li,L., Li,Z., Liu,J., Liu,W., Lu,J.,
            Maheshwari,M., Nguyen,B.V., Okwuonu,G.O., Pasternak,S., Perez,L.M.,
            Plopper,F.J., Santibanez,J., Shen,H., Tabor,P.E., Verduzco,D.,
            Waldron,L., Wang,Q., Williams,G.A., Zhang,J., Zhou,J., Allen,C.C.,
            Amin,A.G., Anyalebechi,V., Bailey,M., Barbaria,J.A., Bimage,K.E.,
            Bryant,N.P., Burch,P.E., Burkett,C.E., Burrell,K.L., Calderon,E.,
            Cardenas,V., Carter,K., Casias,K., Cavazos,I., Cavazos,S.R.,
            Ceasar,H., Chacko,J., Chan,S.N., Chavez,D., Christopoulos,C.,
            Chu,J., Cockrell,R., Cox,C.D., Dang,M., Dathorne,S.R., David,R.,
            Davis,C.M., Davy-Carroll,L., Deshazo,D.R., Donlin,J.E., D'Souza,L.,
            Eaves,K.A., Simons,R., Emery-Cohen,A.J., Escotto,M., Flagg,N.,
            Forbes,L.D., Gabisi,A.M., Garza,M., Hamilton,C., Henderson,N.,
            Hernandez,O., Hines,S., Hogues,M.E., Huang,M., Idlebird,D.G.,
            Johnson,R., Jolivet,A., Jones,S., Kagan,R., King,L.M., Leal,B.,
            Lebow,H., Lee,S., LeVan,J.M., Lewis,L.C., London,P.,
            Lorensuhewa,L.M., Loulseged,H., Lovett,D.A., Lucier,A.,
            Lucier,R.L., Ma,J., Madu,R.C., Mapua,P., Martindale,A.D.,
            Martinez,E., Massey,E., Mawhiney,S., Meador,M.G., Mendez,S.,
            Mercado,C., Mercado,I.C., Merritt,C.E., Miner,Z.L., Minja,E.,
            Mitchell,T., Mohabbat,F., Mohabbat,K., Montgomery,B., Moore,N.,
            Morris,S., Munidasa,M., Ngo,R.N., Nguyen,N.B., Nickerson,E.,
            Nwaokelemeh,O.O., Nwokenkwo,S., Obregon,M., Oguh,M., Oragunye,N.,
            Oviedo,R.J., Parish,B.J., Parker,D.N., Parrish,J., Parks,K.L.,
            Paul,H.A., Payton,B.A., Perez,A., Perrin,W., Pickens,A.,
            Primus,E.L., Pu,L.L., Puazo,M., Quiles,M.M., Quiroz,J.B.,
            Rabata,D., Reeves,K., Ruiz,S.J., Shao,H., Sisson,I., Sonaike,T.,
            Sorelle,R.P., Sutton,A.E., Svatek,A.F., Svetz,L.A., Tamerisa,K.S.,
            Taylor,T.R., Teague,B., Thomas,N., Thorn,R.D., Trejos,Z.Y.,
            Trevino,B.K., Ukegbu,O.N., Urban,J.B., Vasquez,L.I., Vera,V.A.,
            Villasana,D.M., Wang,L., Ward-Moore,S., Warren,J.T., Wei,X.,
            White,F., Williamson,A.L., Wleczyk,R., Wooden,H.S., Wooden,S.H.,
            Yen,J., Yoon,L., Yoon,V., Zorrilla,S.E., Nelson,D.,
            Kucherlapati,R., Weinstock,G. and Gibbs,R.A.
  CONSRTM   Baylor College of Medicine Human Genome Sequencing Center Sequence
            Production Team
  TITLE     The finished DNA sequence of human chromosome 12
  JOURNAL   Nature 440 (7082), 346-351 (2006)
   PUBMED   16541075
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009511.16 and AC009509.7.
            
            On Feb 27, 2020 this sequence version replaced NM_001146221.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.218533.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA1965299,
                                           SAMEA1968968 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000381273.4/ ENSP00000370673.3
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                AC009511.16        58730-58756
            28-562              AC009509.7         184952-185486       c
            563-697             AC009509.7         180569-180703       c
            698-1667            AC009509.7         176331-177300       c
FEATURES             Location/Qualifiers
     source          1..1667
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p11.22"
     gene            1..1667
                     /gene="MANSC4"
                     /note="MANSC domain containing 4"
                     /db_xref="GeneID:100287284"
                     /db_xref="HGNC:HGNC:40023"
     exon            1..27
                     /gene="MANSC4"
                     /inference="alignment:Splign:2.1.0"
     exon            28..562
                     /gene="MANSC4"
                     /inference="alignment:Splign:2.1.0"
     CDS             334..1356
                     /gene="MANSC4"
                     /note="MANSC domain-containing protein 4; MANSC
                     domain-containing protein ENSP00000370673"
                     /codon_start=1
                     /product="MANSC domain-containing protein 4 precursor"
                     /protein_id="NP_001139693.1"
                     /db_xref="CCDS:CCDS53770.1"
                     /db_xref="GeneID:100287284"
                     /db_xref="HGNC:HGNC:40023"
                     /translation="MHVAEVAVNVILLLSMGWTSDSLCSPTIFYRDCWIRRFPGLLIN
                     LEESQKLGAQFLKYYSESTGQKCSRSCCLRKDVSCNLAVFYHSPIHDNINCLHVHCPT
                     LESCILEPGTSAILYNITDGIDPDLLVFEQSPTYLNTRSSSNRWDRLRILKAMNLDKQ
                     TTTINGMLPSTEAPSSTTHQDLVVNTNSTSYSKELTTDFWARFTSLNESITTKINKVS
                     PSTDFISNPDNKTISPFFEPIDTKLSHMPVPPGLNSSKQLLNKTKGYNSRNHTSANED
                     EVSVTSKTWLVSVALCTSVIFLGCCIVILASGCCGKQQGQYKPGQRKSGSLQIKNRNH
                     MKENSS"
     exon            563..697
                     /gene="MANSC4"
                     /inference="alignment:Splign:2.1.0"
     exon            698..1667
                     /gene="MANSC4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggatggcggc ccgggaggag cggcgagaga aagaagaaaa gcagaaaaga gaatgcacgt
       61 cttaagatgc taagggacag ggtattgaaa tagcctggaa agtgttcaga aagaatgcca
      121 gcaaatcaaa tgttcacctg gagctcggga agaaaagaaa aatcaatgtg caaagagtgg
      181 tcttattttg ctagaaagtg actctccaga aaagctgcaa ggaagctctc ccttaacaac
      241 acctctgacg ttccagagac tgtcctaaac tccagtgttc agcttctgtc tggaaatcag
      301 acttatcttc gagtcttcct tcatacagga aaaatgcatg tggcagaggt agcagtgaac
      361 gtgatattgc tcctaagcat ggggtggaca tcagactctc tctgctcacc cacaattttt
      421 tacagagact gctggatccg tcgcttccca ggtcttctaa tcaatctgga ggagtctcag
      481 aagctgggag cccagttctt gaagtattat tctgaaagca ctggccagaa gtgcagtagg
      541 agctgctgtc ttcggaagga tgtttcctgt aacctggctg tcttctacca cagtcctatt
      601 catgacaata tcaactgcct ccatgttcac tgcccaacac tggagagctg catattagag
      661 cctggaacca gtgccatttt gtacaacata acagacggta tagatccgga tttgctggtt
      721 tttgaacaat ctcccacata tctaaatact cgttcttcat ccaatagatg ggacagacta
      781 aggattctaa aagctatgaa tttagataaa caaaccacca cgataaatgg tatgctgcca
      841 tccacagagg ctccatcctc aaccacgcat caagatttgg ttgtaaacac aaacagtacc
      901 agttattcta aggaattaac cacagatttt tgggcaagat ttacttccct gaatgagtcc
      961 attaccacaa agataaataa ggtgtcacca agtactgatt tcatcagcaa tccagataat
     1021 aagactattt ctcctttctt tgaacccata gacacaaaac tttctcatat gcctgttcca
     1081 cctggactca acagtagcaa acaattacta aacaaaacca aaggatacaa tagcagaaac
     1141 cacacatctg caaatgaaga tgaggtatct gtgacttcaa agacttggct ggtttctgtg
     1201 gccctttgca cctctgtcat ctttctcggc tgttgtatag tcatcctggc atctggatgc
     1261 tgtggaaagc agcagggcca gtataaacca ggacagagaa aatcaggatc cttgcaaatt
     1321 aaaaaccgta accatatgaa ggagaactct tcatagtaaa aactgtagca agattatatg
     1381 ctttcaagga tatcattttt agttttgtgt aagaaaacgc agtttggtta aaaaaaaaaa
     1441 ataggctggg cgtggtggtt catgcctgta atcccaaaac tttgggaagc caaggcagta
     1501 gatttgcttg agcccaggag ttcgagacca gcctgggcaa catagtgaga ctctgtctct
     1561 ataaaatgaa aaataattta aaaaaagcac atggggcgat atgatgcacc tgtggtccca
     1621 gctacttagg aggctgaggt gggaggactg cttgagccca ggaggtc
//
