LOCUS       XM_017022185            6414 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens mannosidase alpha class 2A member 2
            (MAN2A2), transcript variant X9, mRNA.
ACCESSION   XM_017022185
VERSION     XM_017022185.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017022185.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6414
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..6414
                     /gene="MAN2A2"
                     /gene_synonym="alpha-MIIx; MANA2X"
                     /note="mannosidase alpha class 2A member 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 5 mRNAs, 130 ESTs, 1497 long SRA reads, 3 Proteins,
                     and 98% coverage of the annotated genomic feature by
                     RNAseq alignments, including 35 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:4122"
                     /db_xref="HGNC:HGNC:6825"
                     /db_xref="MIM:600988"
     CDS             164..3616
                     /gene="MAN2A2"
                     /gene_synonym="alpha-MIIx; MANA2X"
                     /codon_start=1
                     /product="alpha-mannosidase 2x isoform X2"
                     /protein_id="XP_016877674.1"
                     /db_xref="GeneID:4122"
                     /db_xref="HGNC:HGNC:6825"
                     /db_xref="MIM:600988"
                     /translation="MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRHQNGGNFPR
                     SQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTANAEGPPAMLPYYTVNGSWVVPP
                     EPRPSFFSISPQDCQFALGGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHD
                     WDAEDLQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSF
                     FAKWWDNINVQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLER
                     NLGATPRSGWAVDPFGYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQ
                     TWDSDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAIT
                     EANVAERAALLLDQYRKKSQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFN
                     SRPNLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYY
                     TSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRSGLAGRYPLSDFTLLTEARRTLGLF
                     QHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHAAHYLVLGDKETYHFDPEAPFLQ
                     VDDTRLSHDALPERTVIQLDSSPRFVVLFNPLEQERFSMVSLLVNSPRVRVLSEEGQP
                     LAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQLQLGLDGHRTLPSSVRIYLHG
                     RQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSIRRVDEEHEQQVDMQ
                     VLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPFFSEVVAYYEHIHQAVR
                     LYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFTDLNGFQVQPRRYLK
                     KLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGL
                     GQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSMYLNAPALALPVAR
                     MQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKGFDCGLEAK
                     NLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPMEIATFR
                     LRLG"
ORIGIN      
        1 acccctttgc ccgaggggcg caacgacaga gacctaaggc tacctgggcc ggagccgggt
       61 gaggccgcgg agaacgcacc ccgctacgcg tctgccgaga cggaggcggg cgtttcgacc
      121 actgcccgat catgcgctta ctcaagtgtg tgtggaggcc agtatgaagc tgaaaaagca
      181 ggtgacagtg tgtggggctg ccatcttctg tgtggcagtc ttctcgctct acctcatgct
      241 ggaccgagtg caacacgatc ccacccgaca ccagaatggt gggaacttcc cccggagcca
      301 aatttctgtg ctgcagaacc gcattgagca gctggagcag cttttggagg agaaccatga
      361 gattatcagc catatcaagg actccgtgct ggagctgaca gccaacgcag agggcccgcc
      421 cgccatgctg ccctactaca cggtcaatgg ctcctgggtg gtgccaccgg agccccggcc
      481 cagcttcttc tccatctccc cgcaggactg ccagtttgct ttggggggcc ggggtcagaa
      541 gccagagctg cagatgctca ctgtgtcgga ggagctgccg tttgacaacg tggatggtgg
      601 tgtgtggagg caaggcttcg acatctccta cgacccgcac gactgggatg ctgaagacct
      661 gcaggtgttt gtggtgcccc actctcacaa tgacccaggc tggatcaaga cctttgacaa
      721 gtactacaca gagcagaccc aacacatcct caatagcatg gtgtctaagc tgcaggagga
      781 cccccggcgg cgcttcctct gggcagaggt ctccttcttc gccaagtggt gggacaacat
      841 caatgtccaa aagagagcgg cagtccgaag gctggtggga aacgggcagc tggagattgc
      901 gacaggaggc tgggtgatgc cagatgaggc caattcccac tactttgcat tgattgacca
      961 gctcatcgaa ggacaccagt ggctggagag aaatcttggt gcaacccccc gctctggctg
     1021 ggcagtggac ccctttggat acagctccac catgccttac ctgctgcgcc gtgccaacct
     1081 caccagcatg ctgattcaga gagtgcacta tgccatcaag aagcactttg ctgccaccca
     1141 cagcctagag ttcatgtgga ggcagacatg ggactcggac tccagcacag acatcttctg
     1201 tcacatgatg cccttctaca gctatgacgt cccccatacc tgtggcccag atcccaagat
     1261 ctgctgccaa tttgatttca aacgcctgcc tggtgggcgc atcaactgcc cttggaaggt
     1321 gccaccccgg gccatcacag aggccaacgt ggcagagagg gcagccctgc ttctggacca
     1381 ataccggaag aagtcccagc tgttccgaag caacgtcctc ctggtgcctc ttggagatga
     1441 cttccgatat gacaagcccc aggagtggga tgcccagttc ttcaactacc aacggctctt
     1501 tgacttcttc aacagcaggc ctaacctcca tgtgcaggcc cagtttggca ctctttctga
     1561 ctattttgat gccctgtaca agaggacagg ggtggagcca ggggcccggc ctccagggtt
     1621 tcctgtgctg agcggggatt tcttctccta tgcggaccgg gaggatcatt actggacagg
     1681 ctattacact tcccggccct tctacaagag cttagaccga gtcctggaag cccacctgcg
     1741 gggggcagag gttctgtaca gcctggctgc agctcacgct cgccgctctg gtctggctgg
     1801 ccggtaccca ctgtctgatt tcaccctcct gacggaagct cggcgcacat tggggctctt
     1861 ccagcatcac gatgccatca ctggcacggc caaggaggct gtggtggtgg actatggggt
     1921 caggcttctg cgctcccttg tcaacctgaa gcaggtcatc attcatgcag cccactatct
     1981 ggtgctgggg gacaaggaga cctaccactt tgaccctgag gcgcccttcc tccaagtgga
     2041 tgacactcgc ttaagtcacg acgccctccc agagcgcacg gtgatccagc tggattcctc
     2101 gcccaggttt gtggtcctat tcaacccact ggaacaggag cgattcagca tggtgtccct
     2161 gctggtcaac tctccccgcg tgcgtgtcct ttcggaggag ggtcagcccc tggccgtgca
     2221 gatcagcgca cactggagct ctgccaccga ggcggtccct gacgtctacc aggtgtctgt
     2281 gcctgtccgc ctgccagccc tgggcctggg cgtgctgcag ctacagctgg gcctggatgg
     2341 gcaccgcacg ctgccctcct ctgtgcgcat ctacctgcac ggccggcagc tgtccgtcag
     2401 caggcacgaa gcgtttcctc tccgtgtcat tgactctggc accagcgact tcgccctcag
     2461 caaccgctac atgcaggtct ggttctcagg ccttactggg ctcctcaaga gcatccgaag
     2521 ggtggatgag gagcacgagc agcaggtgga catgcaggtc cttgtctatg gcacccgtac
     2581 gtccaaagac aagagtggag cctacctctt cctgcccgat ggcgaggcca agccctacgt
     2641 ccccaaggag ccccccgtgc tgcgtgtcac tgaaggccct ttcttctcag aggtggttgc
     2701 gtactatgag cacattcacc aggcggtccg gctttacaat ctgccagggg tggaggggct
     2761 gtctctggac atatcatccc tggtggacat ccgggactac gtcaacaagg agctggccct
     2821 gcacatccat acagacatcg acagccaggg tatcttcttc acagacctca atggctttca
     2881 ggtgcagccc cgacggtatc tgaagaagct ccccctccag gccaacttct accccatgcc
     2941 agtcatggcc tatatccagg acgcacagaa gcgcctcacg ctgcacactg cccaggccct
     3001 gggtgtctct agcctcaaag atggccagct ggaggtgatc ttggaccggc ggctgatgca
     3061 ggatgacaac cggggcctag gccaagggct caaggacaac aagagaacct gcaaccgttt
     3121 ccgcctcctg ctagagcggc gaaccgtggg cagtgaggtc caagatagcc actctaccag
     3181 ctacccatcc ctcctcagcc acctgacctc catgtacctg aacgccccgg cgctcgctct
     3241 gcctgtagcc aggatgcagc tcccaggccc tggtctgcgc tcatttcatc ctctggcttc
     3301 ctcactgccc tgtgacttcc acctgctcaa cctacgtacg ctccaggctg aggaggacac
     3361 cctaccctcg gcggagaccg cactcatctt acaccgcaag ggttttgact gcggcctgga
     3421 ggccaagaac ttgggcttca actgcaccac aagccaaggc aaggtagccc tgggcagcct
     3481 tttccatggc ctggatgtgg tattccttca gccaacctcc ttgacgttac tgtaccctct
     3541 ggcctccccg tccaacagca ctgacgtcta tttggagccc atggagattg ctacctttcg
     3601 cctccgcttg ggttagggct tcttgtggcc tgaagagaaa gttcattcac agagactgcc
     3661 tcttaacatg aagatcattg gacaagccac acgggtatcc catcccgatc tgcctcccag
     3721 aactgtgaca cactgggctc tgccctcatt ttctgtttat tgctgctgct gtgttttcgg
     3781 cgcaacccac aaacccagtg atgggtaaat agggcagacg ccagtgagat cagggagaga
     3841 aggcccttgg tcagagtggg cagtgccagg ctctgctttg ggttgtgagt ggacacccaa
     3901 ctgggcacag gctcaggcac ccatcctttt tccaaacagg gatatagaag tggtggaagc
     3961 agacagaaga ggtaagggag gctaagtggg taacagccca gcatcagggt cactgtggca
     4021 acagcaggct ctaggggaat cctgtggtta tgtagagact ccatgtcctg gtgtgatgag
     4081 caggatcaga gtgactctgg gaggacaggg gtggggaccc agagttagca gtggggatgg
     4141 agcagtagaa ggaatcactg tttctcctag gagtctgaag gcctcgctgc tttctgtgat
     4201 ggctttgcag taagtgccgc ctggcctgca tgcattggct aacaggctgc agaatggcag
     4261 gaaggactcg ctagagattg tcatggccag agatcatagg tcacttcagg tagcaagacc
     4321 cctggcaaac tgggcacttg gcctatgtac tgatttgtgg gatggtggca ggggtgtggg
     4381 gtccttcacc ctgcctgaat tctctttggc ttctgtgctc tgtatgctgc tgtccccaag
     4441 ggctctttct tattatggca gggagtgggg attggtccta ctttctttct ctggaaagga
     4501 aagcctccaa gactccatgt gcttgggcag cttgagaagg cgttcagcac cacgcctagc
     4561 aggcagacct tgaagcctca cctttagtct atctgcagag gtattcagtt cctggcacag
     4621 gggactaggg gcatgtagag tatatgagga ggcagtatgg ctgtgcagga gccttcattt
     4681 cagcttcaat taatagggaa gaatttatga tagctctata gatgctgaaa aggtatttcg
     4741 taagatttaa aatccatccc ttattaaaac tcttagtaaa ttaagtctgg aaagaaacac
     4801 cctaatctag ataaaggtct gtttcagaaa ccaacagtga tggcattcta aagagtcaga
     4861 cgccacaggc attcccatta aagtcagaaa ctagccaagg gcaagctatt attcagcagt
     4921 gtcccggcac tactaacccc tgcaacaagc cagatgagga acataaggaa gaattataat
     4981 tgtcattatt tgtagacaat aaaactgcct acctgtaaaa cctaagaatc aactgaagac
     5041 ctgttaagag tattctgtaa gtcaacccaa tgatacacat catgttcctg tccacatact
     5101 ggttttcccc aaatcagctg ataaattcag tgtaattcca atgagattga aactttggaa
     5161 ttgacagttc taaagtgcat ttgggagagt gaatgtgtga gaacactaag accactctga
     5221 acgatgataa tgagttgggg ggtggactgc tcgggggtga tcctgccaga ttcccagagg
     5281 attctcacgc caccattacc tcactcagtg tgacctggag ggggtcagac agacgggaga
     5341 gtccagaaac agacccaggg ctacaggaat ttagtatatg gtaagaggga tgttttaagt
     5401 ggggaaaaag gtggattatt taataaacag cacttttaga caactagcta tcaaagctag
     5461 atctcagctg ggtgcgatgg ctcacgcctg taatcccggc actttgggag gccaaggtgg
     5521 gtggatcact tgaggtcagg agttcgagac cagcctggcc aagatggcga aaccctgtgt
     5581 ctactaaaaa tacaaaaact agccaggaat ggtggcgcgc gcctgtaatc ccagttactt
     5641 aggaggctga ggcaggagaa tcacatcaac ctgggaggcg gaggttgcag tgagcttaga
     5701 tcatgccacc atgccactgc actccagcct gggtgacaca gccaaaaaaa aaaccactaa
     5761 gttagatctc tacctcacag tgtccataca aattagttcc agagggaaga tataccacaa
     5821 aattactcaa aaatttttat acctctggtg tgggacggtc ttttctaaac tttaacatga
     5881 gacttaaaag atataataag ggaaaagata agcagatttc gcaaccaaaa aatatcgaaa
     5941 gtctctgtgt gatggaaaac atcaaggtta aaacacaaat gacagatatg gaagaaaata
     6001 tttgcagcac ataaaaaaat caacgagtac aattacttta ggagaaaagc ttgcttcagg
     6061 gtccttagag aaagtcactg gggcctgcca agctgccacc taaagacaag agtgagaggg
     6121 ctgagttctt ccaggtcatc agagttgttg ctgcccgtat taggccacac agtggaaccc
     6181 catttatatc atagcagaag aaataggatt atcaatgtga actgcttagc atggtgcctg
     6241 gtatatacga gagctccaca aatgtgagct ataatcctac tagtaaagga tgctaagcag
     6301 ttccactgtg gcaggtgtca tttgctagta gaatttgtaa tcaaacaata ggaggggaat
     6361 ctgtgaacgc ctagaaaatg agcagaataa aggatattat ctttggaagt ctta
//
