LOCUS       NM_006699               8576 bp    mRNA    linear   PRI 27-MAY-2024
DEFINITION  Homo sapiens mannosidase alpha class 1A member 2 (MAN1A2), mRNA.
ACCESSION   NM_006699
VERSION     NM_006699.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8576)
  AUTHORS   Li,B., Hu,C., Zhao,D., Nie,M. and Wang,X.
  TITLE     Circular RNA circMAN1A2 promotes ovarian cancer progression through
            the microRNA-135a-3p/IL1RAP/TAK1 pathway
  JOURNAL   PeerJ 12, e16967 (2024)
   PUBMED   38680890
  REMARK    GeneRIF: Circular RNA circMAN1A2 promotes ovarian cancer
            progression through the microRNA-135a-3p/IL1RAP/TAK1 pathway.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8576)
  AUTHORS   Ma,G., Li,Y., Meng,F., Sui,C., Wang,Y. and Cheng,D.
  TITLE     Hsa_circ_0000119 promoted ovarian cancer development via enhancing
            the methylation of CDH13 by sponging miR-142-5p
  JOURNAL   J Biochem Mol Toxicol 37 (3), e23264 (2023)
   PUBMED   36482494
  REMARK    GeneRIF: Hsa_circ_0000119 promoted ovarian cancer development via
            enhancing the methylation of CDH13 by sponging miR-142-5p.
REFERENCE   3  (bases 1 to 8576)
  AUTHORS   Zouboulis,C.C., Nogueira da Costa,A., Fimmel,S. and Zouboulis,K.C.
  TITLE     Apocrine glands are bystanders in hidradenitis suppurativa and
            their involvement is gender specific
  JOURNAL   J Eur Acad Dermatol Venereol 34 (7), 1555-1563 (2020)
   PUBMED   32031713
REFERENCE   4  (bases 1 to 8576)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 8576)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   6  (bases 1 to 8576)
  AUTHORS   Cronin,S., Tomik,B., Bradley,D.G., Slowik,A. and Hardiman,O.
  TITLE     Screening for replication of genome-wide SNP associations in
            sporadic ALS
  JOURNAL   Eur J Hum Genet 17 (2), 213-218 (2009)
   PUBMED   18987618
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   7  (bases 1 to 8576)
  AUTHORS   Colland,F., Jacq,X., Trouplin,V., Mougin,C., Groizeleau,C.,
            Hamburger,A., Meil,A., Wojcik,J., Legrain,P. and Gauthier,J.M.
  TITLE     Functional proteomics mapping of a human signaling pathway
  JOURNAL   Genome Res 14 (7), 1324-1332 (2004)
   PUBMED   15231748
REFERENCE   8  (bases 1 to 8576)
  AUTHORS   Tremblay,L.O. and Herscovics,A.
  TITLE     Characterization of a cDNA encoding a novel human Golgi alpha 1,
            2-mannosidase (IC) involved in N-glycan biosynthesis
  JOURNAL   J Biol Chem 275 (41), 31655-31660 (2000)
   PUBMED   10915796
REFERENCE   9  (bases 1 to 8576)
  AUTHORS   Tremblay,L.O., Campbell Dyke,N. and Herscovics,A.
  TITLE     Molecular cloning, chromosomal mapping and tissue-specific
            expression of a novel human alpha1,2-mannosidase gene involved in
            N-glycan maturation
  JOURNAL   Glycobiology 8 (6), 585-595 (1998)
   PUBMED   9592125
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL358072.21, BC063300.1, AL157902.6 and CA449591.1.
            
            On Nov 22, 2018 this sequence version replaced NM_006699.4.
            
            Summary: Alpha-mannosidases function at different stages of
            N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for
            general information.[supplied by OMIM, Mar 2008].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.41230.1,
                                           SRR1660805.227581.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000356554.7/ ENSP00000348959.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-612               AL358072.21        8716-9327
            613-2827            BC063300.1         597-2811
            2828-8503           AL157902.6         36666-42341
            8504-8576           CA449591.1         15-87               c
FEATURES             Location/Qualifiers
     source          1..8576
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p12"
     gene            1..8576
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /note="mannosidase alpha class 1A member 2"
                     /db_xref="GeneID:10905"
                     /db_xref="HGNC:HGNC:6822"
                     /db_xref="MIM:604345"
     exon            1..1037
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     CDS             736..2661
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /EC_number="3.2.1.113"
                     /note="alpha1,2-mannosidase; alpha-1,2-mannosidase IB;
                     processing alpha-1,2-mannosidase IB"
                     /codon_start=1
                     /product="mannosyl-oligosaccharide 1,2-alpha-mannosidase
                     IB"
                     /protein_id="NP_006690.1"
                     /db_xref="CCDS:CCDS895.1"
                     /db_xref="GeneID:10905"
                     /db_xref="HGNC:HGNC:6822"
                     /db_xref="MIM:604345"
                     /translation="MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILS
                     AFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHRE
                     EEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVP
                     IPNLVGIRGGDPEDNDIREKREKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIF
                     GSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLL
                     AAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILA
                     EFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHT
                     SVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKN
                     GHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPE
                     SFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCR
                     VNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDLLPLDHWVFNTEAHPL
                     PVLHLANTTLSGNPAVR"
     exon            1038..1293
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1390
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..1509
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1590
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1685
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1809
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1810..1903
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            1904..2019
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2239
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            2240..2412
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            2413..2528
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            2529..8576
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5036..5041
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /note="hexamer: ATTAAA"
     polyA_site      5056
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /note="major polyA site"
     regulatory      8552..8557
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /note="hexamer: AATAAA"
     polyA_site      8576
                     /gene="MAN1A2"
                     /gene_synonym="MAN1B"
                     /note="major polyA site"
ORIGIN      
        1 agacccgtgc ggtagcaaca gcggcggcgg ccgcggcggc tggccggact caggtgtttc
       61 ggacgctatt gcccttcgcg ccagccgtcg agtgggcagc agcgggactc agccgggcgc
      121 caggttcctg ccaggcagcg ccgggaagcg cgggcggccg agaactcctt cctgctactt
      181 cgcccagcgc cgctgcttcg gcttcccagc gaagtgggag accttcctcc ctgtttgcag
      241 acgtccgtgg gagaccctta ttttttccac cgctaaggtt aagagattct ggaatagaag
      301 cgtcgaagga gatcaagtga accttctaca actcctcgga tgtcgccagt ctccctttcg
      361 gggcggaaga ctacgtttga gcatctcact gaggtgcagg aatggaagaa cccaccttgc
      421 agcttttctg cagtgtggct tgcctgatct acccctagga atgaagagga ggcttgtaat
      481 aatccgatga agtacagatg ttgaagagga tatcgcagga cctaaacttg tgatcgtttg
      541 ggggaggtca cacacgtttc tgagtgggaa tggatgggcg tgaatgacgt gccctcttaa
      601 aaagcacaac agtcctttaa gaggagcaaa attgagtttt cccattttgg ccaagatttt
      661 gaagacagtt caatgtattc tacatttgac ataagatgag aactttctaa agtattctct
      721 ccaagagcgt aaacgatgac taccccagcc ctgctgcccc tctctggacg taggatacca
      781 cctctgaacc tggggccgcc ttccttccca catcacaggg ctaccttgag actttctgag
      841 aagtttattc ttctccttat tcttagtgcc ttcatcactc tgtgttttgg ggcattcttt
      901 ttccttccag actcttcaaa acacaaacgc tttgatttgg gtttagaaga tgtgttaatt
      961 ccacatgtag atgccggtaa aggggctaaa aaccccggag tcttcctgat ccatggaccc
     1021 gatgaacata gacacaggga agaggaagaa cgtctgagaa ataaaattcg agctgatcat
     1081 gagaaggcct tggaagaagc aaaagaaaaa ttaagaaagt caagagagga aattcgagca
     1141 gaaattcaga cagagaaaaa taaggtagtc caagaaatga agataaaaga gaacaagcca
     1201 ctgccaccag tccctattcc caaccttgta ggaatacgtg gtggagaccc agaagataat
     1261 gacataagag agaaaaggga aaaaattaaa gagatgatga aacatgcttg ggataactat
     1321 aggacatatg ggtggggaca taatgaactc agacctattg caaggaaagg acactcccct
     1381 aacatatttg gaagttcaca aatgggtgct accatagtag atgctttgga taccctttat
     1441 atcatgggac ttcatgatga attcctagat gggcaaagat ggattgaaga caaccttgat
     1501 ttcagtgtga attcagaggt gtctgtgttt gaagtcaaca ttcgatttat tggaggccta
     1561 cttgcagcat attacctatc aggagaggag atattcaaga ttaaagcagt gcaattggct
     1621 gagaaactcc ttcctgcctt taacacacct actgggattc cttgggcaat ggtgaatttg
     1681 aaaagtggag tagggcgaaa ctggggctgg gcatctgcag gtagcagcat tctggctgaa
     1741 tttggtacac tacatatgga gttcatccac ctcagctact tgacagggga cctgacttac
     1801 tacaaaaagg ttatgcacat tcggaaacta cttcagaaaa tggatcgtcc aaatggtctt
     1861 tatccaaatt atttgaaccc cagaacaggg cgctggggtc agtatcatac atctgtcggt
     1921 ggcctgggag acagttttta tgaatactta ctgaaagcat ggttgatgtc agataaaaca
     1981 gaccatgagg caagaaagat gtatgatgat gctattgagg ctatagaaaa acatcttatt
     2041 aagaagtctc gtggaggtct tacctttatt ggagaatgga agaatgggca cttggaaaaa
     2101 aagatggggc atttggcctg ctttgctggg ggaatgtttg cactaggagc agatggttcc
     2161 agagcagata aagctggtca ttatttagag ctaggggcag aaattgcacg tacttgtcat
     2221 gagtcatatg acagaactgc attaaagcta ggtcctgaat cattcaagtt tgatggtgca
     2281 gtggaggctg tggctgtccg gcaggctgaa aagtattata tcctccgtcc agaagtaatt
     2341 gaaacctatt ggtacctatg gcgattcact cacgatccaa gatacaggca gtggggctgg
     2401 gaagcagcac tggccattga aaagtattgc cgagttaatg gtgggttttc tggagtcaaa
     2461 gatgtatatt cctctactcc tacacatgat gatgtacagc agagcttttt tcttgctgaa
     2521 acattaaaat atttgtatct gctgttctcc ggtgatgacc ttttaccttt agaccactgg
     2581 gtgtttaata cagaggctca ccctctgcct gtgttacatt tagccaacac cacactttca
     2641 ggtaatcctg ctgttcgatg aaagcagttc cagaaggacc attctcacct gtgttttgtt
     2701 tacatggacc actacagaaa ttagtttgaa ggggcggctt ttgaaaacct ggacctctat
     2761 gtcaacatga cagggtgaaa ctattccccc taagactgtt caacttgtag atacatcaac
     2821 tttgaaatta ttccatttta tacctgacca aaacatgttc tgatatgtgt aggacagaga
     2881 cctggatgtg ctttgatcgt taatgaggtg gtcacatgag aaatgatacc tgttactact
     2941 gtattgtttt tagagtcctg aagtctggag gctagacttc ctgaaagcaa gtcaagaata
     3001 tagagcacct tgcaggagtt caagatggcc tttggaacca attatgtatt tgtttcctcc
     3061 tacagtggag cagcattcaa atcaaatatt tacatattgc ttatcacttt ttctccattt
     3121 taataatgga atgaactaaa ataaacaaga acaaaagaat agtataatta tatcagtaac
     3181 aagaagactc aaaaaagaaa caggagtacc tatccctatc tgaattttca agttccccat
     3241 tggatgacca gactggcaac catttcaaat cccagtctat ttcattgaaa tttcttggtt
     3301 aagtttaatt ttctctgggg gcatgatctc acaaagaata ctcaagtctt tttcttctta
     3361 tggaatcatc gaaactgcta tttatcataa tcaccactta tgagcctggg tttgggattt
     3421 tgtgcatgta gttcagtcta gtgttggtag catgacagaa agtggggaaa atgccgcagt
     3481 ttgttgcctt gaaacctaag agcaatcctt ggttttgttg ctacattatt tttccagacc
     3541 aacacatcta ccaagtaaat tttattcact ttaatttcat aataaagtta gtagagtcac
     3601 tcaacttaca actttattta tgtggcttgg caaaaatcac tataaggcag ctctaaattt
     3661 gccttgataa gctaaataaa ttacttttat aacttactaa agcagaacaa acagtgaaac
     3721 tttctaaaat attctatctg gaatagggac aggggatctt ttatttataa tctcatcaga
     3781 tgagtgagtt gttcacagat attttatgtt tttttaattt tctccaagaa tatttataga
     3841 attccaaaga atcagaatag tttcaaaata attttcagtg ataaaagagt gttgtaatta
     3901 atcatattac actaaaattg ggatacatct aaggaacttt atcttactat cagtaggttt
     3961 tgcattgata tttcttttta aataaactac tagttcttta tattttgaca aaaagaactt
     4021 aaattttatc aggaactgta agataaatat ctagtgctta taaattttct gtccttaaat
     4081 ttatgtgaca gtgcaagata cttttgctct tttcatttaa tataggcatc ttccattgac
     4141 attaataaaa cttagaaaca gtataattag tataacattt actctgaatt tgaagatttc
     4201 ctgaaacaaa gtttgtacaa gaagcccacc ttggaattct gaaggcttat tttcttgttt
     4261 gataagcttt tcttttaaac ttaggtttta agttggggaa agacttaatt aactaatata
     4321 gtattttcta aggttgatca tcttatacca cgaatcgtta attttgacag ttctactgat
     4381 ccgtaaatga taaccactgc aaattttttc agtataaaat ttttcactgc aaaaaaattt
     4441 cagtagaaaa taaggatgca gggccagtta caatagtcct taagagagtt aaattatagc
     4501 acatgttttg acattgtaat atcttttact acttgaacat ttaaatttct aaatgagaaa
     4561 ggtatatata ttactgtaac tgtagaaggg aaaagggaaa gtatttggtt ctaaaaaatg
     4621 ttagccttcc tcgtaaaagt agcacaagcc cacttatgaa tcactgagaa aaagtgaaaa
     4681 acttgagttg gcaaagatgc agagcagcag tgcagatggc aatgaactct ctgaattctc
     4741 ttttacctta tttagaagaa tgcagagtaa agggaccttc ttggttctgc aggaacttct
     4801 caagggatga ggagacagaa cccctacttc caagtgctct atttgtatta cccagatgac
     4861 tgaagcttaa gagaaggcag ggaagtatac aagcagagcc agttctggta caaacaaaga
     4921 atttgacagg gacaatggaa gggtcttctt caccactcct taccttctat gtgatggaaa
     4981 gactagagct tataaaagta cttccatttt tttattctcc tgaataccaa aggcaattaa
     5041 agtcagctac aaatgacttg ccagtgtcat gttttatttt tgttatagat ttttaaatta
     5101 tttccttcaa gatcaattct tatcccatat aatgcttagc ttccaagaat attctttact
     5161 ttcttctgtc ttttacagct ctttgcattt tgtagacctt aatactcagg ttaaatattc
     5221 attgcattta taagatcttc tgcaaaaagc ccagaaatgg tccttttcag gtgcctcttc
     5281 aaagagctga caccttacct tgtgcctttg gcacaaatgt gcagaataga tacatcagtt
     5341 ggtgcataat cgaaaaaaat aggaattttg aacactgttc ttccttctac atttatttct
     5401 cttcatttta gaatcacact ttttatgtta aaccagatta ttattattat tattattcaa
     5461 ccagtattaa gttgttaaaa ccaagggaat ggggccctaa ccaaaaagaa gtctcaactc
     5521 agaaaaataa gtccccagtc aggtggttct tactttcttg tgggttgcac attttgtatc
     5581 tctctaacat cagcgtattc ctgactttaa gcaggtgttt atatgtaaaa taaaacctgg
     5641 gtatcgaagg gaaatgcatt ctttttatgg agtattgacc ctgatcctct atgatgtcat
     5701 atagagcaac tcagggctat acttgctaga ttttaaccaa gcagtttgaa atattaatca
     5761 tcatcctctc atcttctcca ctctccattg ccaaagtctt tgtcaaaact ccaaatttgt
     5821 tgataaaaga ttgtgtttgc cattctcatt tataatgcag tttctcctta agcctggagt
     5881 tttttgaatg agtgcatgag taaatgagag aatgtgtgaa cgaacattta tgaagtatct
     5941 aacatgtgcc aagcattgtg cctggcactt tcaatcatta gaatgtttta tgtgattcca
     6001 cagcattttc tgtatgagag tagctcacaa cattttaaat gtttccaata tgaatcgtgt
     6061 tacaaaattc ttaattttat atttcatata aattaaagag gaaaaagaaa aggtttataa
     6121 tatattttaa aacaatgtgt tactgtataa tacaactata attgtagtta ataactaaaa
     6181 cctcttgaaa atgtcaaaga aatacttgat ttctgatgca actttgacta aaatatttac
     6241 tttagaaata aaaacgttct tattttgcta tatcacttta attgcataat taaaaagcag
     6301 tgttttatag aaatgctggt tattttatat tcaaaaagat tttgtcacat aattcatggg
     6361 taaaacttgc agttgtaaat tgtgtctgct ctggtatggg ccctattaat agtcccatgc
     6421 tgttaaatat aaagaaaaat atactaaaat attcaaagtt ccaaataaca gttcctagta
     6481 atagtatttt gagttatttt tctttaggtt tccttatact caaattggct aggtcctatc
     6541 ttttcctctc tctctctctc tctctctctc tctctctctc tctctatata tatatatata
     6601 tatatatata tatgagagat atatgagata tatgagagat caagatctat atatgtatat
     6661 aaatacaatt atacacagat aatttttaat actctttgtt aacaaacaca gttgaaaact
     6721 ggtttcggct gcacaaataa gcagaatatt tgagtaacta tatatgatat ggagatattt
     6781 taatccattt atcctggctc aagaacactg ataaagatga ttttctgtta ctttagctca
     6841 ttcagatcag gatggacatg ctctttttga tctataactg ttcagccagc ttccagataa
     6901 tattttaggc tatgagagct atacagtctc tcttattact catttctgct gttgaagtat
     6961 cgaaaacaga tagagatact atgtaaagaa tgggcgtagc tatgttccag gaaaacttta
     7021 tttacaaaag cagatggagg gctggatttg gtccatgggt catagttagt gaccctgatc
     7081 ccaagtttat tttgtgttag accctctaac ctttgatctg cgtcttttct gttttgattt
     7141 acataattca tttttaaatc aaaaagatgt gcgtatatat ggttgtgtgt atctgtataa
     7201 cctaaagcta taatattttg ttgtcttgaa agcagataca ctcttcctgg agtctgttca
     7261 ggtttcagga cgattgacta taatgaaaga gacagaatag ggtaagggaa gatgggtatg
     7321 ctatcagcca ttttctttgc cttgtcattt aatgccataa tttcagattc tctatgtaaa
     7381 aagaaggtct gtgtattgtc aaaataatat actctccaag ttctcctgct cattgaccct
     7441 tgaaccagga ttctggattg ctagagctgc agaaattcac ccacttgggt actcttagag
     7501 ctctacagca agaatatgat agaatgtctg atctttgtgc tgcagaaagc aaacttttga
     7561 agaattctaa gcaacagaaa atgggttatg tgactcatct gctatttggc agccactatt
     7621 ccttttttag actgcagaac ggtactgccc ctgttacctc tagaatagcc tgagtctgag
     7681 gagtgcagag aaaagatata tccaaaagga gaatcccttt ctcttgcata actctcaatc
     7741 ctttacaagt aagtagcatt atttcagaat gtctatatgc atcattttca actaaagcat
     7801 acctcatcct taaacttcca ctatttaaca gctaatccat ttcaaacttg gtttgagcct
     7861 agcaattgca gaactcataa aattgcttgt gaaattacac accatattac tagcatatac
     7921 attgcagtgc tccaatcatg ctaacagata atagattttt ctttaagaat tttatcaaat
     7981 atttcactat ttggggaaat tttagaggag gggaagcctg tattcaggat gatagaggga
     8041 gcagagactt actgtctctc ttccacatta taaatgaact gcctttccag gtccaacatg
     8101 ctgtcaggtt gcttcagctc ggtgtgaatg taagtgtggg gatcaaacac acacacctat
     8161 acacatacat attaatatgc agaggatttt aaataattgc aaatgtcttg tggctgtttt
     8221 atttctacaa aattctgtaa gatgtatacc agaaaacata ataaagataa gctcagttct
     8281 tcattgggaa aaaatatttt taaagaaaat ttagaagttt ttgctgaatt aaagtatctt
     8341 caattttaat tactggattt ggaagttgaa atgccatcct tcaatatcac tggtctcaaa
     8401 ttcattgata gaattttttc ttaaactaat aagtggggta agtataatct cctaaattgg
     8461 tacccactgg ctgctcctaa actggtttcc agtcatgtcc tccagtatgt gatttttata
     8521 aattaaaggt aatattgtat attaaagttc aaataaagat gttctttaag tgaaaa
//
