LOCUS       NM_182506               1953 bp    mRNA    linear   PRI 29-JUL-2024
DEFINITION  Homo sapiens MAGE family member B10 (MAGEB10), mRNA.
ACCESSION   NM_182506
VERSION     NM_182506.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1953)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1953)
  AUTHORS   Chomez,P., De Backer,O., Bertrand,M., De Plaen,E., Boon,T. and
            Lucas,S.
  TITLE     An overview of the MAGE gene family with the identification of all
            human members of the family
  JOURNAL   Cancer Res 61 (14), 5544-5551 (2001)
   PUBMED   11454705
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK057527.1, BC101308.2 and
            AC112492.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Apr 10, 2010 this sequence version replaced NM_182506.2.
            
            Summary: This gene encodes a member of the B subfamily of the
            melanoma associated antigen protein family. The encoded protein is
            specifically expressed in testis and tumor cells. [provided by
            RefSeq, Apr 2010].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK057527.1, BC101307.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2148093, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000356790.2/ ENSP00000368304.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-260               AK057527.1         1-260
            261-1585            BC101308.2         243-1567
            1586-1699           AK057527.1         1586-1699
            1700-1953           AC112492.3         2522-2775
FEATURES             Location/Qualifiers
     source          1..1953
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp21.3"
     gene            1..1953
                     /gene="MAGEB10"
                     /note="MAGE family member B10"
                     /db_xref="GeneID:139422"
                     /db_xref="HGNC:HGNC:25377"
                     /db_xref="MIM:300761"
     exon            1..47
                     /gene="MAGEB10"
                     /inference="alignment:Splign:2.1.0"
     exon            48..196
                     /gene="MAGEB10"
                     /inference="alignment:Splign:2.1.0"
     exon            197..1953
                     /gene="MAGEB10"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..1289
                     /gene="MAGEB10"
                     /note="MAGE family testis and tumor-specific protein;
                     MAGE-B10 antigen; melanoma antigen family B, 10; melanoma
                     antigen family B10"
                     /codon_start=1
                     /product="melanoma-associated antigen B10"
                     /protein_id="NP_872312.2"
                     /db_xref="CCDS:CCDS35221.1"
                     /db_xref="GeneID:139422"
                     /db_xref="HGNC:HGNC:25377"
                     /db_xref="MIM:300761"
                     /translation="MPRGQKSKLRAREKRRQARGGLEDLIDALDILEEEEESPPSASA
                     CLKDVFQSSLDGASNNPHGLREAQSTSTSATAASHTRHPEGVNDQMEERPICTQDLEA
                     TDSFPRGPVDEKVIILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRASEHL
                     ELIFGLDLKEVEPNKHIYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGNCV
                     AEEEVWKVFNTMGLYDGIEHFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWG
                     PRAHAETSKMKVLEFLAKVNDTAPSEFSNWYTEALQDEEERARARVAAKARVSATAGA
                     RSKVKSSKSSQLQ"
ORIGIN      
        1 gattggtatc tggtcagcag agaaaggcat ccaggccccg ccaggagaga cggtgcctcg
       61 ctctgttgcc cagactggag tgcagtggtg tgatcataac tcagtatagc ctagaactcc
      121 tgagctcaag caatcctccc acctcagcct ttcaagcagc taggagtaca gttgggagcc
      181 actgtacctg gttactgtca cgggatcacc tgcctttttg gctgctgcac ctgaacagag
      241 tcatcatgcc tcgaggtcag aagagtaaac tccgtgccag ggaaaaacgc cgtcaggccc
      301 gaggagggct ggaagatttg atagatgctc tggacatttt agaagaggag gaagaatctc
      361 ccccctctgc ctctgcttgt ttgaaggatg ttttccagag ttcacttgat ggggcatcca
      421 acaatcccca tggacttcgg gaagcccaat ccaccagcac atctgctaca gctgcttcac
      481 acacaagaca tcccgaagga gtcaacgacc aaatggaaga aaggccaata tgcacacaag
      541 atctagaagc cactgatagc tttcccagag gccctgtaga tgagaaagta attatattgg
      601 tgcattactt gctgtacaag taccaaatga aagagcccat tacaaaggca gatatgctga
      661 gaaatgtaac ccaaatgtcc aagagccagt tccctgtaat cctgagcaga gcttctgagc
      721 acctggagct gatctttggt cttgacctga aggaagtgga gcctaataag cacatctatg
      781 tccttgtcaa caaactagat ctaggctgtg atgcaaagct gagtgatgaa acaggcgtgc
      841 ccaagactgg cctgctgatg actgtcctgg gtattatctt cacaaatggc aattgtgtcg
      901 ctgaggagga agtctggaaa gtgtttaaca cgatggggtt atatgacgga attgagcact
      961 tcatgtttgg ggagcccagg aagctcctta ccaaagattt ggtgaaagaa aattacctgg
     1021 agtaccagca agtgcccaac agtgatcctc cacgctatca attcctatgg ggcccaagag
     1081 cccatgctga aaccagcaag atgaaagttc ttgagttttt ggccaaggta aatgatacag
     1141 ctcccagtga attctcaaac tggtatacag aggctttaca agatgaggaa gagagagcca
     1201 gagccagagt tgcagccaag gctcgcgtta gtgccacagc cggtgcacgt tccaaggtta
     1261 agtccagcaa gtcctcccaa ctgcagtaaa gtctgaggga gattcttcat ttgtgtttga
     1321 aaagaaatgc acattctgag ctgtgggagg tcagggtggg actggagaca acacagtgaa
     1381 taatatgttt gtgttaatgt tctatgtgat ggcttggaat ttttgaagat gttgttcctt
     1441 taatagatgg ttaaagtagc ttcactatct aagtttatga atgacattgc tcaaattttt
     1501 ctgtatgtga gattaagagt aagcgattta ttgctttata agtctaattg ggaaactctc
     1561 catttattta gtgatcgaaa cacgatagca tggtagtaaa ttaggcattt cctaattcaa
     1621 tgtgaaataa tttaggagtg taataaatgg gatcaagaaa tagagcaaag agggtcgggt
     1681 gcggtggctc acacctgtaa tcctagcact ttgggaggcc gaggcaggcg gatcatgagg
     1741 tcaggagatc aagaccatct tggctaacac agtgaaaccc cgtctctact aaaaatacaa
     1801 aaaattagcc aggcgtggtg gcgggttcct gtagtcctag ctgctcagga ggctgaggca
     1861 ggagaatggc gtaaacccgg gaggcggagc ttgcagtgag ccaagatcac acgactgcat
     1921 tctagcctgg gtgacagagc gagactctgt ctc
//
