LOCUS       NM_152367               6376 bp    mRNA    linear   PRI 11-JUN-2024
DEFINITION  Homo sapiens mab-21 like 3 (MAB21L3), mRNA.
ACCESSION   NM_152367
VERSION     NM_152367.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6376)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 6376)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL121982.19 and AK096035.1.
            
            On Aug 10, 2020 this sequence version replaced NM_152367.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038192.3799346.1,
                                           SRR18074968.734284.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000369500.4/ ENSP00000358512.3
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-112               AL121982.19        17428-17539
            113-238             AL121982.19        17658-17783
            239-1171            AK096035.1         1-933
            1172-1172           AL121982.19        34182-34182
            1173-1514           AK096035.1         935-1276
            1515-6376           AL121982.19        39317-44178
FEATURES             Location/Qualifiers
     source          1..6376
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p13.1"
     gene            1..6376
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /note="mab-21 like 3"
                     /db_xref="GeneID:126868"
                     /db_xref="HGNC:HGNC:26787"
     exon            1..112
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /inference="alignment:Splign:2.1.0"
     exon            113..294
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /inference="alignment:Splign:2.1.0"
     exon            295..551
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /inference="alignment:Splign:2.1.0"
     CDS             504..1592
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /note="DANGER family member 5"
                     /codon_start=1
                     /product="protein mab-21-like 3"
                     /protein_id="NP_689580.2"
                     /db_xref="CCDS:CCDS886.1"
                     /db_xref="GeneID:126868"
                     /db_xref="HGNC:HGNC:26787"
                     /translation="MKYLTVGDLEDCLLNKVDLRRQQISQAVEEVQKVVHHLTTNISN
                     QDIRFQAVPYSDTYNENIKVLAPSQFLVTVPIKGLAGYREAREQHWRYYTLQGTRLPC
                     PLRDPEGLQQWLEVEQFMKSLWQWHETDVNIDGDIVPAKVLLVFRKLVENAVRTCHLS
                     GKVSLLGNRSAVWVAVETSAYQVELELVPAVEIPTTWSKKARWPRCLQRWPSQERVEC
                     IKSFGFNLLACSNYHWQLSFLRAEQVLLEQLDEDGGCRRKCFQVMRHLKEDIWCPGNR
                     PVITSHHLQTVLFWTCEKYPHFKDWQVFSKAFLRLVRKLHKCVSQHFLKHYFVRNSNL
                     FQCTNPTELDTVAQKLATFLKNPQIGPP"
     exon            552..692
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /inference="alignment:Splign:2.1.0"
     exon            693..984
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1163
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1358
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..6376
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6349..6354
                     /regulatory_class="polyA_signal_sequence"
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /note="hexamer: ATTAAA"
     polyA_site      6376
                     /gene="MAB21L3"
                     /gene_synonym="C1orf161; D5"
                     /note="major polyA site"
ORIGIN      
        1 gcagagtatg ggaagatatg caaacgctga ggccccaaat agtgcagtgg cctttgtggg
       61 cagcacttac aggtgggctt ggaaacactt gcctttggaa cattgtttaa aataaaacta
      121 gccccagcca gcccaactgg gaatttactg cctgagctgt tttccaacat aagttttgct
      181 ggcaaaacca gacgtgagtg ttccctcgac tctaaaggga cctgtttaca ctgactttat
      241 ttttactgcc agctttcaag ttggaagagg gaaattacgt ttaaaggtca gcagatgaca
      301 gatggatttt cacaatttgg aaataaaaac atgagtgaag ggttcggaag gcaagtctct
      361 ggtccattac acacttccag aaaaacttag tacccagaga ctcacattac tgggagtgct
      421 atctactcac aagtgttgca ctccattgag aaaaaaaaaa aaaccaggaa gttgctgttc
      481 tactgaggac tgaccaagaa gccatgaaat accttactgt gggagactta gaagattgcc
      541 tactgaataa ggtggacttg aggcgccagc agatttccca ggctgtggag gaggtgcaga
      601 aagtcgttca tcatttgacc acaaacatca gcaaccaaga cattagattt caagctgtgc
      661 cttactctga cacgtacaat gaaaatatta aggttttggc tcccagtcag ttcctcgtca
      721 cagtcccaat aaaaggcctg gccgggtaca gggaggccag ggagcagcac tggcggtact
      781 acacactgca gggcaccagg ctgccctgcc cgttgcggga ccctgagggt ctgcagcagt
      841 ggctggaggt ggaacagttt atgaagagcc tgtggcagtg gcatgagaca gatgtgaaca
      901 tcgacggaga cattgtgcct gccaaggtcc tcctagtgtt ccggaagctg gtggaaaatg
      961 cagttagaac ctgtcacctc tcaggtaagg tcagcctgct aggaaaccgc tctgcagttt
     1021 gggttgctgt ggaaacatct gcatatcagg tggaactgga gctggtcccc gcagtggaga
     1081 tccccaccac ctggtccaag aaagcccggt ggcctcgatg tctgcagcgc tggccttccc
     1141 aagagagagt ggagtgcatc aagtcgtttg gatttaactt gttggcctgt tcaaattatc
     1201 actggcagct gagcttcctc cgtgctgagc aggtgttact ggaacagctg gatgaagatg
     1261 ggggctgccg taggaagtgt tttcaggtca tgaggcacct gaaggaggac atctggtgcc
     1321 cagggaacag gccggttatc acgtcccacc atctgcagac tgtgctcttt tggacctgcg
     1381 agaaatatcc ccactttaaa gactggcagg tcttcagcaa agcatttctg cgcctggtga
     1441 ggaaactgca caagtgcgtg agccagcact tcctgaaaca ctatttcgtc cggaacagca
     1501 acctctttca gtgcaccaac ccgactgaac tggacactgt ggcccaaaag ctggccacct
     1561 tcctgaagaa cccccagatc ggcccgccct gatggttgcc ccggcctggg aggctcttgg
     1621 acattttatt ctggcttaac attgttcttt ggatggttcc tcagtcaggt gccaggatcc
     1681 tgcctaggag aaaggccacg aatggcagcg gaaattacat caaaccagaa acacttcagc
     1741 agggggaaaa ctgtgcccca ggatgtctgg cccaggcctc cctggagccc agcaagcatt
     1801 tctgccctag ctaattctcc tggagacagc tctcatcagg cttccccagg cacagatttg
     1861 gaactggtga cagttctgaa cttagtttcc cttgttcagg ctgtgatcgt ctcacagtga
     1921 agatggagac agaacccctg gaagtctgga catgagcctg ctggccaata ctgtgcccag
     1981 cccactgatc atgggcacat tctcctgcca tttgtaaaat gggaatgtta acgtgcctac
     2041 ctctgagcag ggctgtgtgc ctatgaaact gtgctggcgc cttttcaagg ggaaggcatt
     2101 ggatcaacac aaagtgttcc tggttggttg agtagctggt gtttgcatcc tggatcggta
     2161 cccacagcac tgacgcaaaa ttgcacctga tgagttagtg agcctgtgct tccttgctgc
     2221 cctccagctt ccttagcatg tgggtcagtg gctcctgatg ttctgtctgc ttcgctggta
     2281 ttctctaagc agggagggga atggttttga tgataagtgt aagtcaaaga tgaaagtaca
     2341 actcttggcc tgatcccaac catagccctc tctttgcttc ccatgccatg ggccatggat
     2401 ggaacttcct tatatattta tgtaaataac ctagtactat gatctgcatg gagtgacctt
     2461 aggtgtctgt cactgctcag tgtgttcctt tgctcacttc attcactcac tcactcattg
     2521 acaaataatg ctcattaggc accgggaaca cagcaaagag caaagtggat gaggacctcc
     2581 ccctggggat gccacctaat ggtggagaca agaaatgaac gacagataaa cacgcacagt
     2641 tattacagat ggaagcaagt gcttcaaagg aaataaacag aatgttgaag tagagtccac
     2701 agaaaggtcc ccgaaggatg aaaatgcaaa tagctgaagg ggaaggaaaa gtgaccaaag
     2761 gcaggcatgg tggggctggc atgagtcaga gcacctggcc ttgtaaagcc aggaaggaat
     2821 cagtatttta ttctaagatc aaaggtgtga catttggcct ctccagaagc agaagagtat
     2881 cacgatctga ctgcatttta aacaattgtt ctggtaactg catgaagaag gtctggggac
     2941 tcacacagga gctgggcact gagtgctctt gagccaccca tttggaattt cacagaggcc
     3001 cacaaggcaa catattctgt gtggcacaac cgatcaggaa ttctaggagt tctcggtgag
     3061 atcaatggtt tttttctggc gtttatgtaa tgcttctcaa ctcaaggggc tcctttatta
     3121 cttttgaatg tttttgccca aatgtctata ccaaagataa atttctaaag catgaactac
     3181 tgattttgtt ttcatgaaaa ttcacatttg aaaatgaaaa tgattacttt tcaaaagtac
     3241 tgtaaacggc aggaaagatc caaaattgac accctaacat cacaattaaa agaactagaa
     3301 aagcaagagc aaacacattc aaaagctagc agaaggcaag aaataactaa aatcagagca
     3361 gaactgaagg aaatagagac acaaaaaacc cttcaaaaaa ttaatagatc caggagctgg
     3421 ttttttgaaa ggatcaacaa aattgataga ctgctagcaa gactaataaa gaaaaaaaga
     3481 gagaagaatc aaatagatgc aataaaaaat gataaagggg atatcaccac cgatcccaca
     3541 gaaatacaaa ctaccatcag agaatactac aaactcctct acgcaaataa actagaaaat
     3601 ctagaagaaa tggataaatt cctcaacaca tacactctcc caagactaaa ccaggaagaa
     3661 gttgaatctc tgaatagacc aataacagga tctgaaattg tggcaataat caatagctta
     3721 ccaaccaaaa agagtccagg accagatgga ttcacagccg aattctacca gaggtacaag
     3781 gaggaactag taccattcct tctgaaacta ttccaatcaa ttgaaaaaga gggaatcctc
     3841 cctaactcat tttatgaggc cagcatcatc ctgataccaa agccgggcag agacacaact
     3901 aaaaaagaga attttagacc aatatccttg ttgaacattg atgcaaaaat cctcagtaaa
     3961 attctggcaa accgaatcca gcagcacatc aaaaagctta tccaccatga tcaagtgggc
     4021 ttcatccctg ggatgcaagg ctggttcaat atacgcaaat caataaatgt aatccagcat
     4081 ataaacagaa ccaaagacaa aaaccacatg attatctcaa tagatgcaga aaaggccttt
     4141 gacaaaattc aacaaccttc atgctaaaaa ctctcaataa attaggtatt gatgggacgt
     4201 atttcaaaat aataagagct atctatgaca aacccacagg caatatcata ctgaatgggc
     4261 aaaaactgga agcattccct ttgaaaactg gcacaagaca gggatgccct ctctcaccac
     4321 tcctattcaa catagtgttg gaagttctgg ccagggcaat taggcaggag aaggaaataa
     4381 agggtattca attaggaaaa gaggaagtca aattgtccct gtttgcagac aacatgattg
     4441 tatatctaga aaaccccatt gtctcagccc aaaatctcct taagctgata agcaacttca
     4501 gcaaagtctc aggatacaaa atcaaagtac aaaaatcaca agcattctta tacaccaata
     4561 acagacagag agccaaatca tgagtgaact cccattcaca attgcttcaa agagaataaa
     4621 atacttagga atccaactta caagggacgt gaaggacctc ttcaaggaga actacaaacc
     4681 actgctcaat gaaataaaag aggatacaaa caaatggaag aacattccat gctcatgggt
     4741 aggaagaatc aatatcgtca aaatggccag actgcccaag gtaatttaca gattcaatgc
     4801 catccccatc aagctaccaa tgactttctt cacagaattg gaaaaaacta ctttaaagtt
     4861 catatggaac caaaaaagag cctgcattgc caagtcaatt ctaagccaaa agaacaaagc
     4921 tggaggcatc acactacctg acttcaaact atactacaag gctacagtaa ccaaaacagc
     4981 atggtactgg taccaaaaca gggatataga tcaatggaac agaacagagc cctcagaaat
     5041 aacgccgcat atctacaact atctgatctt tgacaaacct gagaaaaaca agcaatgggg
     5101 aaaggattcc ctatttaata aatggtgctg ggaaaactgg ctagccatat gtagaaagct
     5161 gaaactggat cccttcctta caccttatac aaaaattaat tcaagatgga ttaaagactt
     5221 aaacgttaga cctaaaacca taaaaaccct agaagaaaac ctaggcatta ccattcagga
     5281 cataggcatg ggcaaggact tcatgtctaa aacaccaaaa gcaatggcaa caaaagccaa
     5341 aattgacaaa tgggatctaa ttaaactaaa gagcttctgc acagcaaaag aaactaccat
     5401 cagagtgaac aggcaaccta caaaatggga gaaaattttc acaacctact catctgacaa
     5461 agggctaata tccagaatct acaatgaact caaacaaatt tacaagaaaa aaacaaacaa
     5521 ccccaacaaa aagtgggtga aggacatgaa cagacacttc tcaaaagaag acatttatgc
     5581 agccaaaaat cacatgaaaa atgctcatca tcactggcca tcagagaaat gcaaatcaaa
     5641 accacagtga gataccatct cacaccagtt agaatggcaa tcattaaaaa gtcaggaaac
     5701 aacaggtgct ggagaggatg tggagaaata ggaaaacttt tacactgttg gtgggactgt
     5761 aaactagttc aaccattatg gaagtcagtg tggcgattcc tcagggatct agaactagaa
     5821 ataccatttg acccagccat cccattactg ggtatatacc caaaggacta taaatcatgc
     5881 tgctataaag acacatgcac acgtatgttt attgcggcat tattcacaat agcagacttg
     5941 gaaccaaccc aaatatccaa caatgataga gtggattaag aaaatgtggc acatatacac
     6001 catggaatac tatgcagcca taaaaaatga tgagttcatg tcctttgtag ggacatgggt
     6061 gaaattggaa atcatcattc tcagtaaact atcgcaagaa caaaaaacca aacactgcat
     6121 attctcactc ataggtggga attgaacaat gagaacacat ggacacatta agggtaacat
     6181 cacactctgg ggactgttgt ggggtggggg gaggggggag ggatagcatt gggagatata
     6241 cctaatgcta gatgacgagt tagtgggtgc agcgcaccag catggcacat gtatacatat
     6301 gtaactaacc tgcacattgt gcacatgtac cctaaaactt aaagtatgat taaaaaaaaa
     6361 aagtactgta accaaa
//
