LOCUS       NM_153374               1277 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens LysM domain containing 2 (LYSMD2), transcript variant
            1, mRNA.
ACCESSION   NM_153374
VERSION     NM_153374.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1277)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1277)
  AUTHORS   Rush,J., Moritz,A., Lee,K.A., Guo,A., Goss,V.L., Spek,E.J.,
            Zhang,H., Zha,X.M., Polakiewicz,R.D. and Comb,M.J.
  TITLE     Immunoaffinity profiling of tyrosine phosphorylation in cancer
            cells
  JOURNAL   Nat Biotechnol 23 (1), 94-101 (2005)
   PUBMED   15592455
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC033515.1, BQ446302.1 and AC026770.6.
            
            On Nov 22, 2018 this sequence version replaced NM_153374.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163657.48995.1, BC033515.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1966682,
                                           SAMEA2145893 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000267838.7/ ENSP00000267838.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1119              BC033515.1         466-1584
            1120-1224           BQ446302.1         18-122              c
            1225-1277           AC026770.6         10609-10661         c
FEATURES             Location/Qualifiers
     source          1..1277
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q21.2"
     gene            1..1277
                     /gene="LYSMD2"
                     /note="LysM domain containing 2"
                     /db_xref="GeneID:256586"
                     /db_xref="HGNC:HGNC:28571"
     exon            1..306
                     /gene="LYSMD2"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..681
                     /gene="LYSMD2"
                     /note="isoform 1 is encoded by transcript variant 1; lysM
                     and putative peptidoglycan-binding domain-containing
                     protein 2; LysM, putative peptidoglycan-binding, domain
                     containing 2"
                     /codon_start=1
                     /product="lysM and putative peptidoglycan-binding
                     domain-containing protein 2 isoform 1"
                     /protein_id="NP_699205.1"
                     /db_xref="CCDS:CCDS10143.1"
                     /db_xref="GeneID:256586"
                     /db_xref="HGNC:HGNC:28571"
                     /translation="MADSSPALSLREGGPRAPRPSAPSPPPRSRSGSESEEAELSLSL
                     ARTKTRSYGSTASVRAPLGAGVIERHVEHRVRAGDTLQGIALKYGVTMEQIKRANKLF
                     TNDCIFLKKTLNIPVISEKPLLFNGLNSIDSPENETADNSFSQEEEPVVAGEDLPPPS
                     PQESDVQPVQPEEVSARDFLQRLDLQIKLSTQAAKKLKEESRDEESPYATSLYHS"
     exon            307..638
                     /gene="LYSMD2"
                     /inference="alignment:Splign:2.1.0"
     exon            639..1277
                     /gene="LYSMD2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1201..1206
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LYSMD2"
                     /note="hexamer: AATAAA"
     polyA_site      1219
                     /gene="LYSMD2"
                     /note="major polyA site"
     regulatory      1254..1259
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LYSMD2"
                     /note="hexamer: AATAAA"
     polyA_site      1277
                     /gene="LYSMD2"
ORIGIN      
        1 aagctccccg acccggcggc ctcggcagga cccatggcgg attcctcgcc cgcactgtcc
       61 ctgcgggaag gcggcccccg cgcgccgcgg ccctcggccc cctcgccgcc gccgcgctcg
      121 cgctccggct ccgagtccga ggaggccgag ctgtcgctga gcctggcccg caccaagacc
      181 cgctcgtacg gcagcaccgc cagcgtgcgg gcgccgctgg gcgccggcgt catcgagcgc
      241 catgtggagc accgggtccg cgcgggcgac acgctgcagg gcatcgcgct caagtacggt
      301 gtcacgatgg aacagattaa aagggccaat aaactgttta ccaatgattg tatatttctg
      361 aagaaaactt tgaacatccc agttatatca gagaagcctt tgttgtttaa tggacttaac
      421 tccattgatt ctccagaaaa tgaaactgct gataacagtt tttctcagga agaggagcca
      481 gtggtggccg gggaagacct ccctcctccc agtcctcaag aatctgatgt tcagcctgtg
      541 cagcctgagg aagtgtcagc cagagatttc ctgcagagac ttgacttgca gattaagtta
      601 tcaacacagg cagccaagaa gctaaaagaa gagagcagag atgaagaaag tccctatgca
      661 acttccctct atcacagtta ggtgatttgg gggcataact ctaaccaaaa ttaagatatg
      721 tttggaccat aaagaatcca acaactgaag attcaaaaac atcccttctg gattcctata
      781 gtgtccatct taaaatcata actaggtagt tctacctgct gcagttgcac tgaagtgatt
      841 agttccctct ggctttctat aattttaagt ctttattatg gcatgatggc aaggttgtag
      901 cctaaagctc atcacttttg taggtggtgt tagtttttag actagctttt ataaatacta
      961 attgacataa agcatcaaag attatttata tatttaggct aaaaataatg tttatctcct
     1021 tatgcaatcc tgattatgtg aaaatatggt tgctgtttaa gtgatgctga atttgctgtg
     1081 tgtttataac ttaagtgcta tatatatatt tcgatatgtc ttacatattc tctattaata
     1141 taaagaacca aattttgtct gctattttgt aaaaataaac tacaaaagcc tgaatgagaa
     1201 aataaactat gttttcaaac ttgagtctcc tttttttttt taacaaatga gaaaataaaa
     1261 ttgactttta aattata
//
