LOCUS       NM_212551               2462 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens LysM domain containing 1 (LYSMD1), transcript variant
            1, mRNA.
ACCESSION   NM_212551
VERSION     NM_212551.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2462)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL592424.13, DA176882.1 and BX647911.1.
            
            On Nov 23, 2018 this sequence version replaced NM_212551.4.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR3476690.579222.1,
                                           SRR3476690.643028.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2146236, SAMEA2157437
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000368908.10/ ENSP00000357904.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 AL592424.13        59998-60005         c
            9-104               DA176882.1         4-99
            105-1971            BX647911.1         63-1929
            1972-2462           BX647911.1         1938-2428
FEATURES             Location/Qualifiers
     source          1..2462
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.3"
     gene            1..2462
                     /gene="LYSMD1"
                     /gene_synonym="SB145"
                     /note="LysM domain containing 1"
                     /db_xref="GeneID:388695"
                     /db_xref="HGNC:HGNC:32070"
     exon            1..824
                     /gene="LYSMD1"
                     /gene_synonym="SB145"
                     /inference="alignment:Splign:2.1.0"
     CDS             645..1328
                     /gene="LYSMD1"
                     /gene_synonym="SB145"
                     /note="isoform a is encoded by transcript variant 1; lysM
                     and putative peptidoglycan-binding domain-containing
                     protein 1; RP11-68I18.5; LysM, putative
                     peptidoglycan-binding, domain containing 1"
                     /codon_start=1
                     /product="lysM and putative peptidoglycan-binding
                     domain-containing protein 1 isoform a"
                     /protein_id="NP_997716.1"
                     /db_xref="CCDS:CCDS986.1"
                     /db_xref="GeneID:388695"
                     /db_xref="HGNC:HGNC:32070"
                     /translation="MASPSRQPPPGGSGLLQGSRARSYGSLVQSACSPVRERRLEHQL
                     EPGDTLAGLALKYGVTMEQIKRANRLYTNDSIFLKKTLYIPILTEPRDLFNGLDSEEE
                     KDGEEKVHPSNSEVWPHSTERKKQETGAGRANGEVLPTPGQETPTPIHDLSASDFLKK
                     LDSQISLSKKAAAQKLKKGENGVPGEDAGLHLSSPWMQQRAVLGPVPLTRTSRTRTLR
                     DQEDEIFKL"
     exon            825..1189
                     /gene="LYSMD1"
                     /gene_synonym="SB145"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..2462
                     /gene="LYSMD1"
                     /gene_synonym="SB145"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2441..2446
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LYSMD1"
                     /gene_synonym="SB145"
                     /note="hexamer: ATTAAA"
     polyA_site      2462
                     /gene="LYSMD1"
                     /gene_synonym="SB145"
                     /note="major polyA site"
ORIGIN      
        1 cttttctcaa agaccttgcc gctcaactgg atccaggccc ttgcatcttg gcggatctga
       61 ggcgtttgga gggacaacaa cctagatgtg gagccgaaat ttgagggtgt gacctatctt
      121 atgcggagcg gacctttgag gatctctgag tggaaggtgt actacaaatt cttgcaatcc
      181 tcacgctctt cgtctgcggc gacagttcac ctggggtggg cctgatttgt tcctgactct
      241 agcaaacaaa ccccgggacc ggggagagct gggatgttgg agcgccctga ggccaggcta
      301 cttgggggca aactgaggaa agagtgttga ggattatttc tagagttcaa aggtcagagg
      361 tcaatgtagc gaggagttgt gggggagtcc aaagtcggag gggtgcttag gggagaatta
      421 gggagggact gaatactcaa gggacagatt tgtggataag tagcttggag ggaggagaaa
      481 ccgggagggg gcagatggcg tagtgctggg gaggcgggga cacaggggaa gagagagggg
      541 gaaaggaatc ccctgaatat tcattcccag acttcaggcc tgtcagtcgc agtctcggtc
      601 gtacctcccc tagttgcaac cttagctgtt ggcagggtga agagatggct tccccgtcta
      661 gacagccccc gccagggggg tcaggactgc ttcaagggag ccgggctcgt tcatatggaa
      721 gcctggtgca atcggcctgc tccccagtga gggaaagacg cctggagcat cagttggagc
      781 ccggagacac cctggctgga ctagcactca aatatggggt gacgatggaa cagattaaac
      841 gtgcaaaccg cctttatact aatgactcca tcttcctgaa gaaaaccctc tacatcccca
      901 tcctgacaga gcccagagac ctgttcaatg gtttggactc tgaggaagag aaagatggag
      961 aggaaaaagt acacccaagt aacagtgaag tttggccaca ctcaactgag aggaagaaac
     1021 aagagacagg agcaggacgt gccaatggtg aagtcctccc cacacctggc caggaaaccc
     1081 ccacgcccat ccatgacctc tctgcctctg atttccttaa gaagcttgat tcacagatca
     1141 gcctgtccaa gaaggctgct gctcagaagc tgaaaaaagg ggaaaatggg gtacctgggg
     1201 aggatgcagg tctccacctg agctcccctt ggatgcagca acgagcagtc ctaggtcctg
     1261 tgccgctgac ccgtacctct cggacccgga cactacggga ccaggaggat gaaatcttca
     1321 aactctgatg tccccagaac tgactgagag aagcaagatg ttgaaagaga aacttcaggg
     1381 ggagaggagc ctgaggtgag gctcaagaac atggcttatg agcctgcctc cctccactcc
     1441 agccatcctc cccagcctcc ttgtctgcca aaaattcctt ggcctggggc agttttattg
     1501 gcaagattag ggaatgggaa ctggaccttt cccagttctt gggctgaatc tagagttgag
     1561 tcctttagac tcaaaaggct ctttttatat ccttgttgcc tttcctatcc tttttacctt
     1621 tccctggcct tagaacaggg aagcagagac tccccctcag cttcttcctc atctccaact
     1681 atgtgacata atttatttgg tgctaatatt gaagtaatat ttatttgcta tattttattt
     1741 cttcccactc ttagctgaaa aatggaattt ctatagccct ggggtgagga gaacccggga
     1801 acagtgagcc agtgactgct ggttctccac tttccccacc ttgttagcca aacatgttat
     1861 tgaggatgag gcaatcggtg atatagccca ccacagagaa tggatgactg ttggcctttt
     1921 ctccaatctc aaagtgacag atttgggctg attctttttt tttttttttt tggtacccca
     1981 ttcctgttga atgggctcag tcttgacaaa ccaattccct gtaacttttt cacaattctt
     2041 gactctgaga aaaagcagca ctgtagggac ctgaactctc cattctacca gttcaccctt
     2101 ctgacctgtt ctgctcagcc tgtggtgagg ggaacagatg gaagaaggct ttccttgggg
     2161 tttgaagagg aagccagttg tgggagtctc tttgttacac cccctcccct ccagaccctc
     2221 tctctctatg ccttcctcct cactgcatat ttatttgcga tttgtagcac tgatctatgg
     2281 tacagttgtt ttgtttctta aacagaagta ggtaagggaa cctcagtaat aatggaaatc
     2341 tgcctcagtc tcctgtttgg aaatgatgag aggtgagata agtaatgttt atatacctcc
     2401 tttcttctgt gatgattata aggtatacga agctggacag attaaacatt gagccctgtg
     2461 ca
//
