LOCUS       NM_205545                592 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens LY6/PLAUR domain containing 2 (LYPD2), mRNA.
ACCESSION   NM_205545 XM_070613
VERSION     NM_205545.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 592)
  AUTHORS   Oshikawa,M., Tsutsui,C., Ikegami,T., Fuchida,Y., Matsubara,M.,
            Toyama,S., Usami,R., Ohtoko,K. and Kato,S.
  TITLE     Full-length transcriptome analysis of human retina-derived cell
            lines ARPE-19 and Y79 using the vector-capping method
  JOURNAL   Invest Ophthalmol Vis Sci 52 (9), 6662-6670 (2011)
   PUBMED   21697133
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 592)
  AUTHORS   Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
            Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
            Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
            Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
            Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
            Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
            Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
            Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
            Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY358432.1 and DA449804.1.
            
            On May 17, 2019 this sequence version replaced NM_205545.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DA449804.1, DA458243.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2158800, SAMN03267771
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000359228.4/ ENSP00000352163.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-532               AY358432.1         3-534
            533-592             DA449804.1         514-573
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q24.3"
     gene            1..592
                     /gene="LYPD2"
                     /gene_synonym="LYPDC2; UNQ430"
                     /note="LY6/PLAUR domain containing 2"
                     /db_xref="GeneID:137797"
                     /db_xref="HGNC:HGNC:25215"
     exon            1..139
                     /gene="LYPD2"
                     /gene_synonym="LYPDC2; UNQ430"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..459
                     /gene="LYPD2"
                     /gene_synonym="LYPDC2; UNQ430"
                     /note="RGTR430; ly6/PLAUR domain-containing protein 2"
                     /codon_start=1
                     /product="ly6/PLAUR domain-containing protein 2 precursor"
                     /protein_id="NP_991108.1"
                     /db_xref="CCDS:CCDS6388.1"
                     /db_xref="GeneID:137797"
                     /db_xref="HGNC:HGNC:25215"
                     /translation="MRGTRLALLALVLAACGELAPALRCYVCPEPTGVSDCVTIATCT
                     TNETMCKTTLYSREIVYPFQGDSTVTKSCASKCKPSDVDGIGQTLPVSCCNTELCNVD
                     GAPALNSLHCGALTLLPLLSLRL"
     exon            140..259
                     /gene="LYPD2"
                     /gene_synonym="LYPDC2; UNQ430"
                     /inference="alignment:Splign:2.1.0"
     exon            260..592
                     /gene="LYPD2"
                     /gene_synonym="LYPDC2; UNQ430"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      526
                     /gene="LYPD2"
                     /gene_synonym="LYPDC2; UNQ430"
                     /note="major polyA site"
     polyA_site      532
                     /gene="LYPD2"
                     /gene_synonym="LYPDC2; UNQ430"
                     /note="major polyA site"
ORIGIN      
        1 agtctgtcgc cacctcactt ggtgtctgct gtccccgcca ggcaagcctg gggtgagagc
       61 acagaggagt gggccgggac catgcggggg acgcggctgg cgctcctggc gctggtgctg
      121 gctgcctgcg gagagctggc gccggccctg cgctgctacg tctgtccgga gcccacagga
      181 gtgtcggact gtgtcaccat cgccacctgc accaccaacg aaaccatgtg caagaccaca
      241 ctctactccc gggagatagt gtaccccttc cagggggact ccacggtgac caagtcctgt
      301 gccagcaagt gtaagccctc ggatgtggat ggcatcggcc agaccctgcc cgtgtcctgc
      361 tgcaatactg agctgtgcaa tgtagacggg gcgcccgctc tgaacagcct ccactgcggg
      421 gccctcacgc tcctcccact cttgagcctc cgactgtaga gtccccgccc acccccatgg
      481 ccctatgcgg cccagccccg aatgccttga agaagtgccc cctgcaccag gactcctgag
      541 tctcctttct gggcacagac ctgccctgct gcatctctga cctcgtcgat gt
//
