LOCUS       NM_001003693            1023 bp    mRNA    linear   PRI 06-APR-2024
DEFINITION  Homo sapiens lymphocyte antigen 6 family member G6F (LY6G6F), mRNA.
ACCESSION   NM_001003693
VERSION     NM_001003693.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1023)
  AUTHORS   Ucisik-Akkaya,E., Davis,C.F., Do,T.N., Morrison,B.A., Stemmer,S.M.,
            Amadio,W.J. and Dorak,M.T.
  TITLE     Examination of genetic polymorphisms in newborns for signatures of
            sex-specific prenatal selection
  JOURNAL   Mol Hum Reprod 16 (10), 770-777 (2010)
   PUBMED   20587610
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 1023)
  AUTHORS   Barcellos,L.F., May,S.L., Ramsay,P.P., Quach,H.L., Lane,J.A.,
            Nititham,J., Noble,J.A., Taylor,K.E., Quach,D.L., Chung,S.A.,
            Kelly,J.A., Moser,K.L., Behrens,T.W., Seldin,M.F., Thomson,G.,
            Harley,J.B., Gaffney,P.M. and Criswell,L.A.
  TITLE     High-density SNP screening of the major histocompatibility complex
            in systemic lupus erythematosus demonstrates strong evidence for
            independent susceptibility regions
  JOURNAL   PLoS Genet 5 (10), e1000696 (2009)
   PUBMED   19851445
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 1023)
  AUTHORS   Macaulay,I.C., Tijssen,M.R., Thijssen-Timmer,D.C., Gusnanto,A.,
            Steward,M., Burns,P., Langford,C.F., Ellis,P.D., Dudbridge,F.,
            Zwaginga,J.J., Watkins,N.A., van der Schoot,C.E. and Ouwehand,W.H.
  TITLE     Comparative gene expression profiling of in vitro differentiated
            megakaryocytes and erythroblasts identifies novel activatory and
            inhibitory platelet membrane proteins
  JOURNAL   Blood 109 (8), 3260-3269 (2007)
   PUBMED   17192395
REFERENCE   4  (bases 1 to 1023)
  AUTHORS   De Vet,E.C., Aguado,B. and Campbell,R.D.
  TITLE     Adaptor signalling proteins Grb2 and Grb7 are recruited by human
            G6f, a novel member of the immunoglobulin superfamily encoded in
            the MHC
  JOURNAL   Biochem J 375 (Pt 1), 207-213 (2003)
   PUBMED   12852788
  REMARK    GeneRIF: G6f recruits adaptor signalling proteins Grb2 and Grb7.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC137212.1 and AJ496460.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001003693.2.
            
            Summary: The human G6f protein is a type I transmembrane protein
            belonging to the immunoglobin (Ig) superfamily, which is comprised
            of cell-surface proteins involved in the immune system and cellular
            recognition (de Vet et al., 2003 [PubMed 12852788]).[supplied by
            OMIM, Mar 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC137212.1, KU253635.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2144333, SAMEA2149004
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375832.5/ ENSP00000364992.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                BC137212.1         4-44
            42-939              AJ496460.1         1-898
            940-1023            BC137212.1         943-1026
FEATURES             Location/Qualifiers
     source          1..1023
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p21.33"
     gene            1..1023
                     /gene="LY6G6F"
                     /gene_synonym="C6orf21; G6f; LY6G6; LY6G6D; NG32"
                     /note="lymphocyte antigen 6 family member G6F"
                     /db_xref="GeneID:259215"
                     /db_xref="HGNC:HGNC:13933"
                     /db_xref="MIM:611404"
     exon            1..93
                     /gene="LY6G6F"
                     /gene_synonym="C6orf21; G6f; LY6G6; LY6G6D; NG32"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..935
                     /gene="LY6G6F"
                     /gene_synonym="C6orf21; G6f; LY6G6; LY6G6D; NG32"
                     /note="lymphocyte antigen 6 complex locus protein G6f;
                     lymphocyte antigen 6 complex, locus G6D; lymphocyte
                     antigen 6 complex, locus G6F"
                     /codon_start=1
                     /product="lymphocyte antigen 6 complex locus protein G6f
                     precursor"
                     /protein_id="NP_001003693.1"
                     /db_xref="CCDS:CCDS34403.1"
                     /db_xref="GeneID:259215"
                     /db_xref="HGNC:HGNC:13933"
                     /db_xref="MIM:611404"
                     /translation="MAVLFLLLFLCGTPQAADNMQAIYVALGEAVELPCPSPPTLHGD
                     EHLSWFCSPAAGSFTTLVAQVQVGRPAPDPGKPGRESRLRLLGNYSLWLEGSKEEDAG
                     RYWCAVLGQHHNYQNWRVYDVLVLKGSQLSARAADGSPCNVLLCSVVPSRRMDSVTWQ
                     EGKGPVRGRVQSFWGSEAALLLVCPGEGLSEPRSRRPRIIRCLMTHNKGVSFSLAASI
                     DASPALCAPSTGWDMPWILMLLLTMGQGVVILALSIVLWRQRVRGAPGRDASIPQFKP
                     EIQVYENIHLARLGPPAHKPR"
     exon            94..423
                     /gene="LY6G6F"
                     /gene_synonym="C6orf21; G6f; LY6G6; LY6G6D; NG32"
                     /inference="alignment:Splign:2.1.0"
     exon            424..687
                     /gene="LY6G6F"
                     /gene_synonym="C6orf21; G6f; LY6G6; LY6G6D; NG32"
                     /inference="alignment:Splign:2.1.0"
     exon            688..843
                     /gene="LY6G6F"
                     /gene_synonym="C6orf21; G6f; LY6G6; LY6G6D; NG32"
                     /inference="alignment:Splign:2.1.0"
     exon            844..910
                     /gene="LY6G6F"
                     /gene_synonym="C6orf21; G6f; LY6G6; LY6G6D; NG32"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1023
                     /gene="LY6G6F"
                     /gene_synonym="C6orf21; G6f; LY6G6; LY6G6D; NG32"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acaccaggtc ttggagcaag agaacttggc aggctctccc catggcagtc ttattcctcc
       61 tcctgttcct atgtggaact ccccaggctg cagacaacat gcaggccatc tatgtggcct
      121 tgggggaggc agtagagctg ccatgtccct caccacctac tctacatggg gacgaacacc
      181 tgtcatggtt ctgcagccct gcagcaggct ccttcaccac cctggtagcc caagtccaag
      241 tgggcaggcc agccccagac cctggaaaac caggaaggga atccaggctc agactgctgg
      301 ggaactattc tttgtggttg gagggatcca aagaggaaga tgccgggcgg tactggtgcg
      361 ctgtgctagg tcagcaccac aactaccaga actggagggt gtacgacgtc ttggtgctca
      421 aaggatccca gttatctgca agggctgcag atggatcccc ctgcaatgtc ctcctgtgct
      481 ctgtggtccc cagcagacgc atggactctg tgacctggca ggaagggaag ggtcccgtga
      541 ggggccgtgt tcagtccttc tggggcagtg aggctgccct gctcttggtg tgtcctgggg
      601 aggggctttc tgagcccagg agccgaagac caagaatcat ccgctgcctc atgactcaca
      661 acaaaggggt cagctttagc ctggcagcct ccatcgatgc ttctcctgcc ctctgtgccc
      721 cttccacggg ctgggacatg ccttggattc tgatgctgct gctcacaatg ggccagggag
      781 ttgtcatcct ggccctcagc atcgtgctct ggaggcagag ggtccgtggg gctccaggca
      841 gagatgcctc gattcctcag ttcaaacccg aaatccaggt ctatgagaac atccatttgg
      901 cccgtcttgg cccacctgcc cacaagccca ggtgattttg gtgacatctg ctgggaagtg
      961 tgacctgctg tctcgctggc catctggcac ctggaagatt cctcgacaac cttagcaagg
     1021 ggg
//
