LOCUS       XM_047432505            2202 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens leukocyte receptor tyrosine kinase (LTK),
            transcript variant X10, mRNA.
ACCESSION   XM_047432505
VERSION     XM_047432505.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2202
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..2202
                     /gene="LTK"
                     /gene_synonym="TYK1"
                     /note="leukocyte receptor tyrosine kinase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 8 ESTs, 7 long SRA reads, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 23 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:4058"
                     /db_xref="HGNC:HGNC:6721"
                     /db_xref="MIM:151520"
     CDS             464..1843
                     /gene="LTK"
                     /gene_synonym="TYK1"
                     /codon_start=1
                     /product="leukocyte tyrosine kinase receptor isoform X7"
                     /protein_id="XP_047288461.1"
                     /db_xref="GeneID:4058"
                     /db_xref="HGNC:HGNC:6721"
                     /db_xref="MIM:151520"
                     /translation="MELAVDNVTCMDLHKPPGPLVLMVAVVATSTLSLLMVCGVLILV
                     KQKKWQGLQEMRLPSPELELSKLRTSAIRTAPNPYYCQVGLGPAQSWPLPPGVTEVSP
                     ANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALII
                     SKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQL
                     AQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGD
                     RALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGG
                     GRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQDPDVLNSLLPMELGP
                     TPEEEGTSGLGNRSLECLRPPQPQELSPEKLKSWGGSPLGPWLSSGLKPLKSRGLQPQ
                     NLWNPTYRS"
ORIGIN      
        1 ccgcggggag aggcgggcgt gctccccgtg tggctgccaa ccttcctgct gtcgctctgc
       61 aggtggtggg ggcggctgga cgtcgcgggc tccctctccg caggccggcc gctcactgca
      121 ggagggggcg gagggcggcc agggctgctc cgaggcttgg gcgacccttg gctgggccgc
      181 ggccggcggc ttcgggggcg gcggcggggc ctgcactgcg ggcggaggcg gcggcggcta
      241 cagggggggc gacgcttcag agactgacaa cctctgggct gatggggaag atggagtatc
      301 cttcatacac cccagcagcg agctcttcct gcagcctctg gcagtcaccg agaaccacgg
      361 agaggtagag atccgaaggc acctcaactg cagtcactgc cctttgagag actgccaatg
      421 gcaggcagag ctccagctgg ctgaatgcct gtgcccagaa ggcatggagc tagctgtgga
      481 taacgtcacc tgcatggacc tgcacaagcc cccaggccct ctggttctga tggtggctgt
      541 ggtggcaacc tcaacactga gcctccttat ggtgtgtggg gtcctgattc tggtgaagca
      601 gaagaagtgg cagggcctgc aggagatgag gctgccgagc cctgagcttg agctgagcaa
      661 gcttcgaacc tctgccatca ggacagcccc caatccctat tattgccagg tggggcttgg
      721 cccggcccag tcctggcctc tgccaccagg tgtcaccgag gtttccccag ccaatgttac
      781 tctgctcaga gccctgggcc atggtgcctt tggggaggtg tatgagggac tggtaattgg
      841 ccttcctggg gactccagtc ccctgcaggt agctatcaag accctgccag aactctgctc
      901 gcctcaggat gagctggatt tcctcatgga ggccctcatc atcagcaagt ttcgccatca
      961 gaacattgtg cggtgtgtgg ggctcagcct cagggccacc cctcgcctca ttctgctgga
     1021 actgatgtct ggaggggaca tgaagagttt cctgaggcac agtcggccac acctgggcca
     1081 gccatcacct ctggtcatgc gggacctgct gcaactggcc caggacatag cccagggctg
     1141 ccactacctg gaggaaaatc acttcatcca cagggatatt gccgcccgga actgcctgct
     1201 gagctgcgct ggacccagcc gagtggccaa gattggggac tttgggatgg cacgagatat
     1261 ctaccgggcc agttattacc gcagggggga ccgggccttg ctcccagtca agtggatgcc
     1321 cccagaggcc ttcctggagg gcatcttcac atccaagaca gattcctggt cttttggggt
     1381 gctgctctgg gagatcttct cactgggcta catgccctat cctgggcgca ccaaccagga
     1441 ggtgctggac ttcgtcgttg gaggaggccg gatggaccct cctaggggct gcccagggcc
     1501 tgtgtaccgc atcatgaccc agtgttggca gcacgagcct gagctccgcc ctagctttgc
     1561 cagcatcttg gagcgtctgc agtactgcac tcaggacccg gatgtgctga attcactcct
     1621 gccaatggag ctggggccca ccccagagga ggaagggact tctgggctgg ggaacagatc
     1681 tttggagtgc ctaagacccc cacagcccca ggaactgagt ccagagaagt tgaaaagctg
     1741 gggaggtagc cctcttggcc cctggctgtc ctctggcctc aagcccctca aatccagggg
     1801 cctccaacct cagaaccttt ggaatcccac ttatcgctcc tgagccccaa ggggccctga
     1861 gggtaaggac tgaggcactg agggtccctc cctatactcc tcaggctcct gggtggcctg
     1921 ttatgccagc ggcctctgtt ccctgcagtc tgtgctgtgt gtctgggcct gtctcggggc
     1981 tggcctggca gcgctgcact tgccatgctg gaaaccagcc caggcctccc agggaagggc
     2041 ccagccactt ccagcttttg atcttggggc cagaggccgc cttacacaca ccccaggtgt
     2101 ccatggggag cactggattg ctctcccatt atgagcatcc ttcatctggg cagacccccc
     2161 accctgcaga tgcttctaat aaaaagctct tctcatcctc ca
//
