LOCUS       XM_047444383            5012 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens latent transforming growth factor beta
            binding protein 1 (LTBP1), transcript variant X37, mRNA.
ACCESSION   XM_047444383
VERSION     XM_047444383.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5012
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..5012
                     /gene="LTBP1"
                     /gene_synonym="ARCL2E"
                     /note="latent transforming growth factor beta binding
                     protein 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 85 ESTs, 922 long SRA reads, 2
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 117 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:4052"
                     /db_xref="HGNC:HGNC:6714"
                     /db_xref="MIM:150390"
     CDS             143..4048
                     /gene="LTBP1"
                     /gene_synonym="ARCL2E"
                     /codon_start=1
                     /product="latent-transforming growth factor beta-binding
                     protein 1 isoform X37"
                     /protein_id="XP_047300339.1"
                     /db_xref="GeneID:4052"
                     /db_xref="HGNC:HGNC:6714"
                     /db_xref="MIM:150390"
                     /translation="MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSC
                     QNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGK
                     LCQIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIH
                     VKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVI
                     PHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPS
                     YHGYNQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDP
                     TFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCP
                     LPGTAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGI
                     STIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTDIDECTQVQHLCSQ
                     GRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS
                     GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLE
                     PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFR
                     CTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCE
                     DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGEC
                     LNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
                     APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTD
                     LDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVL
                     GTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYEC
                     YCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIR
                     PAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCP
                     LKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
                     CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCI
                     NTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE"
ORIGIN      
        1 agagacacca ctgaatacag agcagcgagc actgaaggct tccctctttc cttaaacctg
       61 tcgggttgtg ggctctctct tttcccctct tgctcctttc ttttcttttt ttctgttttt
      121 ttaaaccttc caaggcaagt tcatggatac taagctgatg tgtttgttgt tctttttctc
      181 cctgcctccg ctcctagtga gtaaccacac tggccgcatc aaggtggtct ttactccgag
      241 catctgtaaa gtgacctgca ccaagggcag ctgtcagaac agctgtgaga aggggaacac
      301 caccactctc attagtgaga atggtcatgc tgccgacacc ctgacggcca cgaacttccg
      361 agtggtaatt tgccatcttc catgtatgaa tggtggccag tgcagttcaa gggacaaatg
      421 tcagtgccct ccaaatttca caggaaaact ttgtcagatc ccagtccatg gtgccagcgt
      481 gcctaaactt tatcagcatt cccagcagcc aggcaaggcg ttggggacgc atgtcatcca
      541 ttcaacacat accttgcctc tgaccgtgac tagccagcaa ggagtcaaag tgaaatttcc
      601 tcctaacata gtcaatatcc atgtgaaaca tcctcctgaa gcttccgtcc agatacatca
      661 ggtttcaaga attgatggcc caacaggcca gaagacaaaa gaagctcaac caggccaatc
      721 ccaagtctcg taccaagggc ttcctgtcca gaagacccag accatacatt ccacatactc
      781 ccaccagcag gtcattcctc acgtctaccc cgtggctgct aagacacagc ttggccggtg
      841 cttccaggaa accattgggt cacagtgtgg caaagcgctc cctggccttt caaagcaaga
      901 ggactgctgt ggaactgtgg gtacctcctg gggctttaac aaatgccaga aatgccccaa
      961 gaaaccatct tatcatggat acaaccaaat gatggaatgc ctaccgggtt ataagcgggt
     1021 taacaacacc ttttgccaag atattaatga atgtcagcta caaggtgtat gccctaatgg
     1081 tgagtgtttg aataccatgg gcagctatcg atgtacctgc aaaataggat ttgggccgga
     1141 tcctaccttt tcaagttgtg ttcctgatcc ccctgtgatc tcggaagaga aagggccctg
     1201 ttaccgactt gtcagttctg gaagacagtg tatgcaccct ctgtctgttc acctcaccaa
     1261 gcagctctgc tgttgtagtg tgggcaaggc ctggggccca cactgtgaga aatgtcccct
     1321 tccaggcaca gccaaggaag agccagtgga ggccctgacc ttctcccggg aacacgggcc
     1381 aggagtggcg gagccagaag tggcaactgc accccctgaa aaggaaatac cttcattgga
     1441 tcaagagaaa accaaacttg agcctggtca accccagctg tctccaggca tttccactat
     1501 tcatctgcat ccacagtttc caggtatagt gattgaaaaa acatcacctc ctgtgcctgt
     1561 tgaagtagct cctgaagctt ctacgtctag tgccagccaa gtgattgctc ctactcaagt
     1621 gacagatatt gatgagtgta ctcaggtcca acacctctgc tcccagggcc gctgtgaaaa
     1681 caccgaggga agtttcttgt gcatttgccc agcaggattt atggccagtg aggagggtac
     1741 taactgcata gatgttgacg aatgcctgag gccggacgtc tgtggggagg ggcactgtgt
     1801 caatactgtg ggggccttcc ggtgtgaata ctgtgacagc gggtaccgca tgactcagag
     1861 aggccgttgt gaggatattg atgaatgttt gaatccaagc acttgtccag atgagcagtg
     1921 tgtgaattct cctggatctt accagtgcgt tccctgcaca gaaggattcc gaggctggaa
     1981 tggacagtgc cttgatgtgg acgagtgcct ggaaccaaac gtctgcgcaa atggtgattg
     2041 ttccaacctt gaaggctcct acatgtgttc atgccacaaa ggctataccc ggactccgga
     2101 ccacaagcac tgtagagata ttgatgaatg tcagcaaggg aatctatgtg taaacgggca
     2161 gtgcaaaaat accgagggct ccttcaggtg cacctgtgga caggggtacc agctgtcggc
     2221 agctaaagac cagtgtgaag acattgatga atgccagcac cgtcatctct gtgctcatgg
     2281 gcagtgcagg aacactgagg gctcttttca atgtgtgtgt gaccagggtt acagagcatc
     2341 tgggcttgga gaccactgtg aagatatcaa tgaatgcttg gaggacaaga gtgtttgcca
     2401 gagaggagac tgcattaata ctgcagggtc ctatgattgt acttgtccgg atggatttca
     2461 gctagatgac aataaaacat gtcaagatat taatgaatgt gaacatccag ggctctgtgg
     2521 tccgcaaggg gagtgcctaa acacagaggg ttctttccat tgtgtctgcc agcagggttt
     2581 ctcaatctct gcagatggcc gtacgtgtga agatattgat gaatgtgtaa acaacactgt
     2641 ttgtgacagt cacgggtttt gtgacaatac agctggctcc ttccgctgcc tctgttatca
     2701 gggctttcaa gccccacagg atgggcaagg gtgtgtggat gtgaatgaat gtgaactgct
     2761 cagtggggtg tgtggtgaag ccttctgtga aaacgtggaa gggtccttcc tgtgcgtgtg
     2821 tgctgatgaa aaccaagagt acagccccat gactgggcag tgccgctccc ggacctccac
     2881 agatttagat gtagatgtag atcaacccaa agaagaaaag aaagaatgct actataatct
     2941 caatgacgcc agtctctgtg ataatgtgtt ggcccccaat gtcacgaaac aagaatgctg
     3001 ctgtacatca ggcgtgggat ggggagataa ctgcgaaatc ttcccctgcc cggtcttggg
     3061 aactgctgag ttcactgaaa tgtgtcccaa agggaaaggt tttgtgcctg ctggagaatc
     3121 atcttctgaa gctggtggtg agaactataa agatgcagat gaatgcctac tttttggaca
     3181 agaaatctgc aaaaatggtt tctgtttgaa cactcggcct gggtatgaat gctactgtaa
     3241 gcaagggacg tactatgatc ctgtgaaact gcagtgcttt gatatggatg aatgtcaaga
     3301 ccccagtagt tgtattgatg gccagtgtgt taatacagag ggctcttaca actgcttctg
     3361 tactcacccc atggtcctgg atgcgtcaga aaaaagatgt atacgaccgg ctgagtcaaa
     3421 cgaacaaata gaagaaactg atgtctacca agatttgtgc tgggaacatc tgagtgatga
     3481 atacgtgtgt agccggcctc ttgtgggcaa gcagacaacg tacactgagt gctgctgtct
     3541 gtatggagag gcctggggca tgcagtgtgc cctctgcccc ctgaaggatt cagatgacta
     3601 tgctcagctg tgtaacatcc ccgtgacggg acgccggcag ccatatggac gggacgcctt
     3661 ggttgacttc agtgaacagt atactccaga agccgatccc tacttcatcc aagaccgttt
     3721 tctaaatagc tttgaggagt tacaggctga ggaatgcggc atcctcaatg gatgtgaaaa
     3781 tggtcgctgt gtgagggtcc aggaaggtta cacctgcgat tgctttgatg ggtatcactt
     3841 ggatacggcc aagatgacct gtgtcgatgt aaatgaatgc gatgagttga acaaccggat
     3901 gtctctctgc aagaatgcca agtgcattaa caccgatggt tcctacaagt gtttgtgtct
     3961 gccaggctac gtgccttctg acaagccaaa ctactgcact ccgttgaata ccgccttgaa
     4021 tttagagaaa gacagtgacc tggagtgaaa cagaatctac ataacctaag cccatatact
     4081 ctgcactgtg taaaggaaaa gggagaaatg tattatactt gagacattgc acctaccccg
     4141 gaaggctgga aatacagaaa cagcatggaa ttgcaagtcc tctgaagaca atgagaggat
     4201 ttaggatgag cccgataggt gtggcagacc aaatggacat ttctctaaaa aaccagtata
     4261 tatagtctgt tcatatgtaa aattcaatgg aagagaggtg gaacagtgct gttattttaa
     4321 acagaaggtt gtattattat gttgttttgt ttttttacta ttgcttgatt aaatttggca
     4381 tttaaatagt ggtggaaata ttttatataa ttttcatttt ttggttgtgc agttccttgg
     4441 ctactgtttt tcttttactt cagtttttta aaaatctcaa atgaaaaagt cttcgataca
     4501 atattgttaa gctgtattat aagtattgtt acacagggtt atgcaattcc cggcctggag
     4561 catttttgaa attcaaattg tctgtcctgt ggagcaggca gtgattttgt tccaaaactt
     4621 tgtatacaca tttggagaaa agtactttat attttcagtg ttttgtctga ttttaatgtc
     4681 cgttcttagc caagctgcta gcaggtgtta attggatccc tttccttcac tgaaatggaa
     4741 gagtttataa gcttacgtta gtattgtaat atgtaaagta agcccaacaa aaatttttaa
     4801 aaatttgatg atccccaata tatctaccat tgtatgttaa ataaatcacc atttttgtag
     4861 aaaaaattct acctgagagt aattgtcaat gagtacatgt gtataagttg tatcccactc
     4921 tccccacttt tatcttttcc agtggtcttc tgttaatgta gtgtctttta caagttaatc
     4981 attaaatttg ttagatcttg ttatgggcta aa
//
