LOCUS       XM_017004110            6256 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens latent transforming growth factor beta
            binding protein 1 (LTBP1), transcript variant X15, mRNA.
ACCESSION   XM_017004110
VERSION     XM_017004110.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017004110.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6256
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..6256
                     /gene="LTBP1"
                     /gene_synonym="ARCL2E"
                     /note="latent transforming growth factor beta binding
                     protein 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 67 ESTs, 551 long SRA
                     reads, 2 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 68 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:4052"
                     /db_xref="HGNC:HGNC:6714"
                     /db_xref="MIM:150390"
     CDS             373..5292
                     /gene="LTBP1"
                     /gene_synonym="ARCL2E"
                     /codon_start=1
                     /product="latent-transforming growth factor beta-binding
                     protein 1 isoform X15"
                     /protein_id="XP_016859599.1"
                     /db_xref="GeneID:4052"
                     /db_xref="HGNC:HGNC:6714"
                     /db_xref="MIM:150390"
                     /translation="MAGAWLRWGLLLWAGLLASSAHGRLRRITYVVHPGPGLAAGALP
                     LSGPPRSRTFNVALNARYSRSSAAAGAPSRASPGVPSERTRRTSKPGGAALQGLRPPP
                     PPPPEPARPAVPGGQLHPNPGGHPAAAPFTKQGRQVVRSKVPQETQSGGGSRLQVHQK
                     QQLQGVNVCGGRCCHGWSKAPGSQRCTKPSCVPPCQNGGMCLRPQLCVCKPGTKGKAC
                     ETIAAQDTSSPVFGGQSPGAASSWGPPEQAAKHTSSKKADTLPRVSPVAQMTLTLKPK
                     PSVGLPQQIHSQVTPLSSQSVVIHHGQTQEYVLKPKYFPAQKGISGEQSTEGSFPLRY
                     VQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADT
                     LTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQPG
                     KALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTG
                     QKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
                     QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFC
                     QDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRL
                     VSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGV
                     HRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPE
                     VATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPE
                     ASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCV
                     DIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHC
                     VNTVGAFRCEYCDSGYRMTQRGRCEDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTR
                     TPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRH
                     LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDC
                     TCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED
                     VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKE
                     EKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCP
                     KGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP
                     VKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE
                     TDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQL
                     CNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENG
                     RCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLC
                     LPGYVPSDKPNYCTPLNTALNLEKDSDLE"
ORIGIN      
        1 ggagtgtccc gcgcgctctc gctcgctctc ggccaccctc gccgggcccc gctgcggcgc
       61 gcgctgcaac ccccggccgg acgcgcggac cctcaccttg cgcggcccgc tcccctcgcc
      121 cctccccgct ccccgggctc cgcgctcccc acccccacgc cctcctcctg ctcccagcca
      181 caatcggccg gggtctgggg ccgctcagct gcccgcagag cctcctccct cgccaccgac
      241 ttggtctcct cccgcctttc ccgggctctc ggcagctctc gggggagccc gaacgcgcgg
      301 ggaaaggcga gccgcacggc cgggggaggg ggccggaccg cgcgcgaccg gtcgcgcccg
      361 ctggggcccg cgatggcggg ggcctggctc aggtgggggc tcctgctctg ggcagggctc
      421 ctcgcgtcct cggcgcacgg ccggctgcgg aggatcacct acgtggtgca cccgggcccc
      481 ggcctggcag ccggcgcctt gcccctgagc gggcccccgc gttcgcggac attcaacgtc
      541 gcgctcaacg ccaggtacag ccgcagctcg gcggctgccg gcgcccccag ccgtgcctcc
      601 cccggggtcc cctcggagag gacccggcgc acgagcaagc cgggcggcgc ggccctgcag
      661 gggctcagac cgccgccgcc gccgccgccg gagcctgcgc gtcccgcggt ccccggcggg
      721 cagctccacc ccaatcccgg cggccacccg gcagccgccc cgttcaccaa acaaggcagg
      781 caagttgtgc gctccaaggt gccgcaggag acccagagcg gcggaggctc taggctgcag
      841 gttcaccaga agcagcagct gcagggggtc aatgtctgtg gagggcggtg ctgtcatggc
      901 tggagtaagg cccctggctc ccagaggtgc accaaaccta gctgtgttcc gccatgtcag
      961 aatggaggga tgtgtctccg gccacaactc tgtgtgtgta aaccagggac caagggcaaa
     1021 gcctgtgaaa caatagctgc ccaggacacc tcgtcaccag tctttggagg gcagagtcct
     1081 ggggctgctt cctcgtgggg ccctcctgag caagcagcaa agcatacttc atctaagaag
     1141 gcagacactc taccaagagt cagccctgtg gcccagatga ccttaaccct caagccgaag
     1201 ccttcagtgg gactccccca gcagatacat tctcaagtga ctcctctttc ttcccagagt
     1261 gtggtgattc accatggcca gacccaggaa tacgtgctca agcccaagta ctttccagcc
     1321 cagaagggga tttcaggaga gcagtccact gaaggttctt tccctttaag atatgtgcag
     1381 gatcaagttg cggcaccttt tcagctgagt aaccacactg gccgcatcaa ggtggtcttt
     1441 actccgagca tctgtaaagt gacctgcacc aagggcagct gtcagaacag ctgtgagaag
     1501 gggaacacca ccactctcat tagtgagaat ggtcatgctg ccgacaccct gacggccacg
     1561 aacttccgag tggtaatttg ccatcttcca tgtatgaatg gtggccagtg cagttcaagg
     1621 gacaaatgtc agtgccctcc aaatttcaca ggaaaacttt gtcagatccc agtccatggt
     1681 gccagcgtgc ctaaacttta tcagcattcc cagcagccag gcaaggcgtt ggggacgcat
     1741 gtcatccatt caacacatac cttgcctctg accgtgacta gccagcaagg agtcaaagtg
     1801 aaatttcctc ctaacatagt caatatccat gtgaaacatc ctcctgaagc ttccgtccag
     1861 atacatcagg tttcaagaat tgatggccca acaggccaga agacaaaaga agctcaacca
     1921 ggccaatccc aagtctcgta ccaagggctt cctgtccaga agacccagac catacattcc
     1981 acatactccc accagcaggt cattcctcac gtctaccccg tggctgctaa gacacagctt
     2041 ggccggtgct tccaggaaac cattgggtca cagtgtggca aagcgctccc tggcctttca
     2101 aagcaagagg actgctgtgg aactgtgggt acctcctggg gctttaacaa atgccagaaa
     2161 tgccccaaga aaccatctta tcatggatac aaccaaatga tggaatgcct accgggttat
     2221 aagcgggtta acaacacctt ttgccaagat attaatgaat gtcagctaca aggtgtatgc
     2281 cctaatggtg agtgtttgaa taccatgggc agctatcgat gtacctgcaa aataggattt
     2341 gggccggatc ctaccttttc aagttgtgtt cctgatcccc ctgtgatctc ggaagagaaa
     2401 gggccctgtt accgacttgt cagttctgga agacagtgta tgcaccctct gtctgttcac
     2461 ctcaccaagc agctctgctg ttgtagtgtg ggcaaggcct ggggcccaca ctgtgagaaa
     2521 tgtccccttc caggcacagc tgcttttaag gaaatctgtc ctggtggaat gggttatacg
     2581 gtttctggcg ttcatagacg caggccaatc catcaccatg taggtaaagg acctgtattt
     2641 gtcaagccaa agaacactca acctgttgct aaaagtactc atcctccacc tctcccagcc
     2701 aaggaagagc cagtggaggc cctgaccttc tcccgggaac acgggccagg agtggcggag
     2761 ccagaagtgg caactgcacc ccctgaaaag gaaatacctt cattggatca agagaaaacc
     2821 aaacttgagc ctggtcaacc ccagctgtct ccaggcattt ccactattca tctgcatcca
     2881 cagtttccag tagtgattga aaaaacatca cctcctgtgc ctgttgaagt agctcctgaa
     2941 gcttctacgt ctagtgccag ccaagtgatt gctcctactc aagtgacaga aatcaatgaa
     3001 tgtactgtga accctgatat ctgtggagca ggacactgca ttaacctacc agtgagatat
     3061 acctgtatat gctacgaggg ctacaggttc agtgaacaac agaggaaatg tgtggatatt
     3121 gatgagtgta ctcaggtcca acacctctgc tcccagggcc gctgtgaaaa caccgaggga
     3181 agtttcttgt gcatttgccc agcaggattt atggccagtg aggagggtac taactgcata
     3241 gatgttgacg aatgcctgag gccggacgtc tgtggggagg ggcactgtgt caatactgtg
     3301 ggggccttcc ggtgtgaata ctgtgacagc gggtaccgca tgactcagag aggccgttgt
     3361 gaggatgtgg acgagtgcct ggaaccaaac gtctgcgcaa atggtgattg ttccaacctt
     3421 gaaggctcct acatgtgttc atgccacaaa ggctataccc ggactccgga ccacaagcac
     3481 tgtagagata ttgatgaatg tcagcaaggg aatctatgtg taaacgggca gtgcaaaaat
     3541 accgagggct ccttcaggtg cacctgtgga caggggtacc agctgtcggc agctaaagac
     3601 cagtgtgaag acattgatga atgccagcac cgtcatctct gtgctcatgg gcagtgcagg
     3661 aacactgagg gctcttttca atgtgtgtgt gaccagggtt acagagcatc tgggcttgga
     3721 gaccactgtg aagatatcaa tgaatgcttg gaggacaaga gtgtttgcca gagaggagac
     3781 tgcattaata ctgcagggtc ctatgattgt acttgtccgg atggatttca gctagatgac
     3841 aataaaacat gtcaagatat taatgaatgt gaacatccag ggctctgtgg tccgcaaggg
     3901 gagtgcctaa acacagaggg ttctttccat tgtgtctgcc agcagggttt ctcaatctct
     3961 gcagatggcc gtacgtgtga agatgtgaat gaatgtgaac tgctcagtgg ggtgtgtggt
     4021 gaagccttct gtgaaaacgt ggaagggtcc ttcctgtgcg tgtgtgctga tgaaaaccaa
     4081 gagtacagcc ccatgactgg gcagtgccgc tcccggacct ccacagattt agatgtagat
     4141 gtagatcaac ccaaagaaga aaagaaagaa tgctactata atctcaatga cgccagtctc
     4201 tgtgataatg tgttggcccc caatgtcacg aaacaagaat gctgctgtac atcaggcgtg
     4261 ggatggggag ataactgcga aatcttcccc tgcccggtct tgggaactgc tgagttcact
     4321 gaaatgtgtc ccaaagggaa aggttttgtg cctgctggag aatcatcttc tgaagctggt
     4381 ggtgagaact ataaagatgc agatgaatgc ctactttttg gacaagaaat ctgcaaaaat
     4441 ggtttctgtt tgaacactcg gcctgggtat gaatgctact gtaagcaagg gacgtactat
     4501 gatcctgtga aactgcagtg ctttgatatg gatgaatgtc aagaccccag tagttgtatt
     4561 gatggccagt gtgttaatac agagggctct tacaactgct tctgtactca ccccatggtc
     4621 ctggatgcgt cagaaaaaag atgtatacga ccggctgagt caaacgaaca aatagaagaa
     4681 actgatgtct accaagattt gtgctgggaa catctgagtg atgaatacgt gtgtagccgg
     4741 cctcttgtgg gcaagcagac aacgtacact gagtgctgct gtctgtatgg agaggcctgg
     4801 ggcatgcagt gtgccctctg ccccctgaag gattcagatg actatgctca gctgtgtaac
     4861 atccccgtga cgggacgccg gcagccatat ggacgggacg ccttggttga cttcagtgaa
     4921 cagtatactc cagaagccga tccctacttc atccaagacc gttttctaaa tagctttgag
     4981 gagttacagg ctgaggaatg cggcatcctc aatggatgtg aaaatggtcg ctgtgtgagg
     5041 gtccaggaag gttacacctg cgattgcttt gatgggtatc acttggatac ggccaagatg
     5101 acctgtgtcg atgtaaatga atgcgatgag ttgaacaacc ggatgtctct ctgcaagaat
     5161 gccaagtgca ttaacaccga tggttcctac aagtgtttgt gtctgccagg ctacgtgcct
     5221 tctgacaagc caaactactg cactccgttg aataccgcct tgaatttaga gaaagacagt
     5281 gacctggagt gaaacagaat ctacataacc taagcccata tactctgcac tgtgtaaagg
     5341 aaaagggaga aatgtattat acttgagaca ttgcacctac cccggaaggc tggaaataca
     5401 gaaacagcat ggaattgcaa gtcctctgaa gacaatgaga ggatttagga tgagcccgat
     5461 aggtgtggca gaccaaatgg acatttctct aaaaaaccag tatatatagt ctgttcatat
     5521 gtaaaattca atggaagaga ggtggaacag tgctgttatt ttaaacagaa ggttgtatta
     5581 ttatgttgtt ttgttttttt actattgctt gattaaattt ggcatttaaa tagtggtgga
     5641 aatattttat ataattttca ttttttggtt gtgcagttcc ttggctactg tttttctttt
     5701 acttcagttt tttaaaaatc tcaaatgaaa aagtcttcga tacaatattg ttaagctgta
     5761 ttataagtat tgttacacag ggttatgcaa ttcccggcct ggagcatttt tgaaattcaa
     5821 attgtctgtc ctgtggagca ggcagtgatt ttgttccaaa actttgtata cacatttgga
     5881 gaaaagtact ttatattttc agtgttttgt ctgattttaa tgtccgttct tagccaagct
     5941 gctagcaggt gttaattgga tccctttcct tcactgaaat ggaagagttt ataagcttac
     6001 gttagtattg taatatgtaa agtaagccca acaaaaattt ttaaaaattt gatgatcccc
     6061 aatatatcta ccattgtatg ttaaataaat caccattttt gtagaaaaaa ttctacctga
     6121 gagtaattgt caatgagtac atgtgtataa gttgtatccc actctcccca cttttatctt
     6181 ttccagtggt cttctgttaa tgtagtgtct tttacaagtt aatcattaaa tttgttagat
     6241 cttgttatgg gctaaa
//
