LOCUS       NM_001195280            1071 bp    mRNA    linear   PRI 03-AUG-2024
DEFINITION  Homo sapiens leucine rich repeat containing 72 (LRRC72), mRNA.
ACCESSION   NM_001195280 XM_001715578 XM_001716919 XM_001717229 XM_002344292
VERSION     NM_001195280.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1071)
  AUTHORS   Rose,J.E., Behm,F.M., Drgon,T., Johnson,C. and Uhl,G.R.
  TITLE     Personalized smoking cessation: interactions between nicotine dose,
            dependence and quit-success genotype score
  JOURNAL   Mol Med 16 (7-8), 247-253 (2010)
   PUBMED   20379614
  REMARK    GeneRIF: Clinical trial of gene-disease association and
            gene-environment interaction. (HuGE Navigator)
            Erratum:[Mol Med. 2012;18(1):729]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC005014.2, AW341438.1, BF222754.1, DT932641.1 and DT932642.1.
            
            On May 17, 2019 this sequence version replaced NM_001195280.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.313963.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000401542.3/ ENSP00000384971.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-55                AC005014.2         59995-60049
            56-64               AW341438.1         446-454             c
            65-201              BF222754.1         311-447             c
            202-798             DT932641.1         1-597
            799-849             DT932642.1         32-82               c
            850-1071            AC005014.2         114517-114738
FEATURES             Location/Qualifiers
     source          1..1071
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7p21.1"
     gene            1..1071
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /note="leucine rich repeat containing 72"
                     /db_xref="GeneID:100506049"
                     /db_xref="HGNC:HGNC:42972"
     exon            1..218
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..992
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /note="leucine-rich repeat-containing protein
                     ENSP00000371558"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 72"
                     /protein_id="NP_001182209.1"
                     /db_xref="CCDS:CCDS56464.1"
                     /db_xref="GeneID:100506049"
                     /db_xref="HGNC:HGNC:42972"
                     /translation="MSWDPNPVPRTLRCWRLRRASETALQSSRRAVEDQLKICGHRRD
                     ADVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIF
                     EIEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYII
                     YHLPGVELLDRNQVTEKERRSMITIFNHKKAHIVQSIAFGGKVDASWDPKSPFKQKPA
                     QRVPSDFAFANNVDKTVLDDPEDAVFVRSMKRSVMTLTSMNWDTVPTREERYLEEEGT
                     ETAQMLTVTLR"
     exon            219..292
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /inference="alignment:Splign:2.1.0"
     exon            293..362
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /inference="alignment:Splign:2.1.0"
     exon            363..444
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /inference="alignment:Splign:2.1.0"
     exon            445..555
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /inference="alignment:Splign:2.1.0"
     exon            556..645
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /inference="alignment:Splign:2.1.0"
     exon            646..798
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /inference="alignment:Splign:2.1.0"
     exon            799..826
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /inference="alignment:Splign:2.1.0"
     exon            827..1071
                     /gene="LRRC72"
                     /gene_synonym="CFAP279; FAP279"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtcaacggg aatgcggtaa ctgttggtaa cagaacaacg agctgtgcac caagccaagt
       61 ctctcttcgg tgccaccggc gggcgaggcc ggattaatca ccgctgcttc ggccgcccat
      121 gtgtcctgat gtcctgggac ccgaaccccg tgccccgtac cttgcgatgc tggcgcctac
      181 ggagggcatc cgaaactgcc ctacagagca gtcgccgggc agttgaagat cagctaaaga
      241 tatgtggcca caggagggat gctgatgtct ttgagctgtt cctttctaaa aaggaactga
      301 cagaggtcat tgatctttct aggtttaaaa aattaaaata cttatggctt catcataaca
      361 agctccatgg aataacattt ctaactagaa actattgtct gacagaacta tatctaaaca
      421 acaatgcaat atttgagata gaaggtctgc attatttgcc ttcattgcat atactcctgc
      481 tacaccacaa tgagctaacc aacattgatg caacagtgaa ggaattaaag ggaatgctaa
      541 atctgaagat cctaagtcta taccaaaatc ctttgtgcca atataacctg tatcgtttat
      601 atatcatcta ccaccttcca ggagtggagc tgcttgaccg aaatcaagtt acagaaaaag
      661 aaagaagatc aatgattacc atttttaacc ataaaaaggc tcatatcgtt caatcaatag
      721 cattcggagg aaaagtggat gcttcatggg atcctaaatc accatttaag caaaaaccag
      781 cccagagagt accttcagat tttgcatttg caaataatgt agacaaaact gtgcttgatg
      841 acccagaaga tgctgttttt gtgaggtcca tgaagagatc agtgatgact ttgacctcta
      901 tgaactggga cacagttcca acacgagagg aaaggtacct tgaagaggaa ggcacagaaa
      961 cagctcaaat gctcacagtt acactgagat aagccctggt atttctagat atcttagtgg
     1021 ttttcagttg tatattaaac ttccctgtga cttagcatat tacatactta c
//
