LOCUS       NM_144702               1977 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens leucine rich repeat containing 71 (LRRC71), mRNA.
ACCESSION   NM_144702
VERSION     NM_144702.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1977)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1977)
  AUTHORS   Bonaldo,M.F., Lennon,G. and Soares,M.B.
  TITLE     Normalization and subtraction: two approaches to facilitate gene
            discovery
  JOURNAL   Genome Res 6 (9), 791-806 (1996)
   PUBMED   8889548
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK292342.1, BC033790.1, BU689904.1 and AL356104.6.
            
            On Nov 23, 2018 this sequence version replaced NM_144702.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK292342.1, BC033790.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000337428.8/ ENSP00000336661.7
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-975               AK292342.1         1-975
            976-1656            BC033790.1         958-1638
            1657-1971           BU689904.1         19-333              c
            1972-1977           AL356104.6         25315-25320
FEATURES             Location/Qualifiers
     source          1..1977
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.1"
     gene            1..1977
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /note="leucine rich repeat containing 71"
                     /db_xref="GeneID:149499"
                     /db_xref="HGNC:HGNC:26556"
     exon            1..332
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     CDS             173..1852
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /note="leucine-rich repeat-containing protein C10orf92"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 71"
                     /protein_id="NP_653303.2"
                     /db_xref="CCDS:CCDS44249.1"
                     /db_xref="GeneID:149499"
                     /db_xref="HGNC:HGNC:26556"
                     /translation="MSSEQSAPGASPRAPRPGTQKSSGAVTKKGERAAKEKPATVLPP
                     VGEEEPKSPEEYQCSGVLETDFAELCTRWGYTDFPKVVNRPRPHPPFVPSASLSEKAT
                     LDDPRLSGSCSLNSLESKYVFFRPTIQVELEQEDSKSVKEIYIRGWKVEERILGVFSK
                     CLPPLTQLQAINLWKVGLTDKTLTTFIELLPLCSSTLRKVSLEGNPLPEQSYHKLMAL
                     DSTIAHLSLRNNNIDDRGAQLLGQALSTLHSCNRTLVSLNLGFNHIGDEGAGYIADGL
                     RLNRSLLWLSLAHNRIQDKGALKLAEVLRAFELTHTEVVERRRLLLEKGTQERSRSPS
                     SSRHGDSKTDREKSQMVGISNSALVDKTDKTQTMKTPKGLGKKKEKSWELAKKEEKLG
                     SGQSPTQGTPKKEDATKAGKGKVTIPEQKPSRAKGIKIGSREKRSILLESELVVEATE
                     VVNPLLEPVEHRDGKVFMPGNKVLLHLNLIRNRITEVGLEGFLATVQYQMQFSKAKSA
                     SKGPVGLLWLSLAKNCFAPQCPAYAIIQELMLPRDPIKAKLREDEAMAFFP"
     exon            333..482
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            483..611
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            612..687
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            688..765
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            766..834
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            835..994
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1078
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1168
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1318
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1412
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..1501
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1613
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            1614..1735
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     exon            1736..1977
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1948..1953
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /note="hexamer: AACAAA"
     polyA_site      1977
                     /gene="LRRC71"
                     /gene_synonym="C1orf92"
                     /note="major polyA site"
ORIGIN      
        1 gttgtcttgg agagggacgc gtaggctacg ccaccgcgga cgggtcggat ccggtccctg
       61 gacgcggaac agagatcccc tgattcagcc acccccagac tgagccccgt agagtgcgtt
      121 cttaccttcc tgccccgacg aaggtcccag agacgctgcg gacaacacca gcatgtcgag
      181 cgagcagagc gcgccggggg cctcacccag ggccccgcgt ccggggaccc agaagtcttc
      241 tggcgcggtg accaaaaagg gagagcgcgc ggccaaagag aagccagcga ccgttctgcc
      301 tcccgtgggg gaggaggagc ccaaaagccc tgaggagtac cagtgctccg gggtcctcga
      361 gaccgacttc gccgagctct gcacgcggtg gggctacacg gacttcccca aagttgtcaa
      421 ccggccccgc ccccacccgc ccttcgtccc ctccgcctct ttgtcggaaa aggccacctt
      481 agacgatccg cggctgtcgg ggtcctgcag cctcaatagc ctggagagca aatacgtgtt
      541 cttccggccc accatccagg tggagctgga gcaggaggac agcaagtcag tgaaggaaat
      601 ctacatccgc ggttggaagg ttgaggaacg gattctgggt gtcttctcta aatgtctgcc
      661 cccgcttacc cagctacagg ccatcaactt gtggaaggtg gggctgaccg ataagaccct
      721 gaccaccttc atcgagctcc tgcctctctg ttcatccacg ctcaggaagg tgtctctgga
      781 ggggaaccca ctgccggagc agtcctatca caagctcatg gccttggaca gcacgattgc
      841 gcacttgtct ctgcggaaca ataacatcga cgaccgcggg gcgcaactcc tgggccaggc
      901 gctgtccacg ctgcacagct gcaaccggac cctcgtctcg ctcaacctgg gtttcaacca
      961 catcggtgac gagggcgcag gctacatcgc ggacggcctc cggctgaacc gttccctgct
     1021 ctggctgtcc ctggcccaca accgcatcca ggacaagggc gccctgaagc tggctgaggt
     1081 cctgcgcgcc ttcgagctga cacacaccga agtggtggag cgccgacgcc tcctgctgga
     1141 aaaagggaca caggagcgct cgcgatcgcc ctcctcctct cgacacgggg actccaaaac
     1201 ggaccgtgag aagagtcaga tggtagggat cagcaatagt gcattggtgg acaagacaga
     1261 caagacgcag acaatgaaaa cccctaaggg cctgggcaag aaaaaggaga aatcatggga
     1321 attggccaag aaagaggaga agttggggtc tgggcagtca cccacacaag gaacccctaa
     1381 gaaggaagat gccacaaagg caggcaaggg gaaggtaacc atccctgaac agaagccaag
     1441 cagggcaaaa gggatcaaga tcgggagcag agagaagcgc agcatcctcc tggagtccga
     1501 gctggttgtt gaggctactg aggtggtcaa ccctctcctg gagcctgtgg agcaccgaga
     1561 tgggaaagtt ttcatgcctg ggaacaaggt ccttttgcac ctcaacctca tccggaaccg
     1621 catcacagag gtggggctgg agggcttcct cgccacggtg cagtatcaga tgcagttctc
     1681 caaggccaag agtgcatcca agggtccagt ggggctgctg tggctgtccc tggctaaaaa
     1741 ttgcttcgcc ccacaatgtc ctgcgtacgc cataatccag gagctgatgt tgccaaggga
     1801 tcccatcaag gccaaactca gggaggatga ggccatggca ttcttcccct agccccctcc
     1861 cacctgcttg cctctaagac tcggggctac agaagcacct cctgtccctg tgtggggtga
     1921 cctccctggg ggagatctca gaccaataac aaagtctgtt gctatacttt tccttga
//
