LOCUS       NM_001145077            2270 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens leucine rich repeat containing 10B (LRRC10B), mRNA.
ACCESSION   NM_001145077 XM_001715247 XM_372416 XM_938096
VERSION     NM_001145077.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Chen,J., Hu,L., Chen,J., Wu,F., Hu,D., Xu,G., Zhu,P. and Wang,Y.
  TITLE     Low expression lncRNA RPLP0P2 is associated with poor prognosis and
            decreased cell proliferation and adhesion ability in lung
            adenocarcinoma
  JOURNAL   Oncol Rep 36 (3), 1665-1671 (2016)
   PUBMED   27460542
  REMARK    GeneRIF: LRRC10B may be a downstream gene regulated by RPLP0P2
REFERENCE   2  (bases 1 to 2270)
  AUTHORS   Taylor,T.D., Noguchi,H., Totoki,Y., Toyoda,A., Kuroki,Y., Dewar,K.,
            Lloyd,C., Itoh,T., Takeda,T., Kim,D.W., She,X., Barlow,K.F.,
            Bloom,T., Bruford,E., Chang,J.L., Cuomo,C.A., Eichler,E.,
            FitzGerald,M.G., Jaffe,D.B., LaButti,K., Nicol,R., Park,H.S.,
            Seaman,C., Sougnez,C., Yang,X., Zimmer,A.R., Zody,M.C.,
            Birren,B.W., Nusbaum,C., Fujiyama,A., Hattori,M., Rogers,J.,
            Lander,E.S. and Sakaki,Y.
  TITLE     Human chromosome 11 DNA sequence and analysis including novel gene
            identification
  JOURNAL   Nature 440 (7083), 497-500 (2006)
   PUBMED   16554811
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP003108.3 and AW137416.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001145077.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: DRR138524.964381.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000378075.4/ ENSP00000367315.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1890              AP003108.3         180937-182826
            1891-2270           AW137416.1         12-391              c
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.2"
     gene            1..2270
                     /gene="LRRC10B"
                     /note="leucine rich repeat containing 10B"
                     /db_xref="GeneID:390205"
                     /db_xref="HGNC:HGNC:37215"
     exon            1..2270
                     /gene="LRRC10B"
                     /inference="alignment:Splign:2.1.0"
     CDS             251..1129
                     /gene="LRRC10B"
                     /note="LRRC10-like protein ENSP00000367315"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 10B"
                     /protein_id="NP_001138549.1"
                     /db_xref="CCDS:CCDS44621.1"
                     /db_xref="GeneID:390205"
                     /db_xref="HGNC:HGNC:37215"
                     /translation="MGIAESTPDELPSDAEEQLRSGDQQLELSGRRLRRLPSAVCALS
                     RLQKLYVSGTGLRELPEEIEELRELRILALDFNKLERLPDGLCRLPRLTRLYLGGNRL
                     LALPADFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTG
                     LRGLWLYGNRFEEFPPALLRMGRLHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTG
                     PPRVADTVFLVGEGAVERMAERDEPTPRPPPRRPARAFEDEEEEDLLIGGAGSRALGA
                     PGGSFRALEAAPGLGT"
     regulatory      2249..2254
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRRC10B"
                     /note="hexamer: ATTATA"
     polyA_site      2270
                     /gene="LRRC10B"
                     /note="major polyA site"
ORIGIN      
        1 agtcggcctc cggcggaggc aacgggggag gcccgagggc gggcggtgga gcgcggcgcg
       61 cggcggcggt gccccaagtg ggtgcctcct cccggccccg cacggccccc ctcccggcgc
      121 gggggaaggc cggggcgggg ggcccggggg ccggcgcggc tccggcaccg tcggggcggc
      181 tggggggcgg ccggggcggg gcgatgcctg gcggtggcag tggcggcggc cccggccggg
      241 gcccgtgacc atgggcatcg ccgagtccac gccggatgag ctgccgtcgg acgcagagga
      301 gcagctgcgc agcggcgacc agcagctgga gctgagcggg cggcggttgc ggcggctgcc
      361 cagcgcagtg tgcgcgctga gccgcctgca gaagctgtat gtgagcggca cggggctgcg
      421 cgagctgccg gaggagatcg aggagctgcg cgagctgcgc atcctggcgc tggacttcaa
      481 caagctcgag cgactgcctg acggcctgtg ccgcctgccg cgcctcacgc gcctctatct
      541 gggcggcaac cggctgctgg cgctgcccgc cgacttcgcg cagttgcaga gcctgcgctg
      601 cctctggatc gagggcaact tcttgcggcg cttcccgcgg ccgctgctgc gcctggtggc
      661 gctgcagtcg ctccagatgg gcgacaaccg gctgcgcgcg ctgccggccg agctgccgcg
      721 catgacgggc ttgcgcggcc tctggctcta cggcaaccgc ttcgaggagt tcccgcccgc
      781 gctgctgcgc atgggccgcc tgcacatcct cgacctcgac cgcaaccgcc tgggcggctt
      841 ccccgacctg cacccgctgc gcgcgctgcg cgtcttctcc tacgaccaca accccgtcac
      901 cgggcccccg cgcgtcgcgg acaccgtgtt cctcgtgggc gagggcgccg tcgagcgcat
      961 ggcggagcgc gacgagccca cgccccggcc tccgccccgg cgcccagcgc gggcctttga
     1021 ggatgaggag gaggaagacc tgctcatagg cggcgctggt tcccgggctc tgggcgcccc
     1081 cgggggcagc ttccgcgccc tggaagccgc tccaggactg ggcacctgag cctatgttct
     1141 ggctgatggg cttcagccac tctgagagga ggggctctag gaagctttgg ctggttaggc
     1201 ctgcgggact ggtgggtccc tacttaggtc aatggaacgg ctacttttgg cgagttgccg
     1261 ggcacaggca gggctggggc tcatcttcag acactcctag gtagtaagag gactgactat
     1321 accctggctg atctgtgggc aattgtcaga ccaagaagtc tgggctgggt ccagtccccg
     1381 atggagccac tgataacaga ggcaccagct tcctcctgga accagggtct ctgagggcca
     1441 cagaattgtc acgtctccct gagtctggat gcagggcacc caacaccctc cctctttctg
     1501 gggtttgggt ctcctaggcc caccctttct aggacaggag ccgctacctc tgggatggac
     1561 tgcgtgcctg tgtggggcag gactgccctt gcgaggaggg cctggcccag gagcaggggc
     1621 ttggagtggg gctggtgccc gggacagaag tgggaaatag atgggggccc caacaccgaa
     1681 gctgccctca cccctccatc agggctgatc gtacatacct ccctcctcgg ccccctgaga
     1741 ttggtatggg gcacagaagg cagggggtca cccccaccct attctgttct cttctcccag
     1801 cctcccagca tgtgcctgga accttgctgg gaagagagag ctccccctcc actccccacc
     1861 ccatagcctg agccttccag ctgtcaagtt tgaaaagaag ccaccgtgcc tccagggcct
     1921 cctgcaccgc agagaggggc tctctgctct gggaggctgc tcagcgcctc tcccacggcc
     1981 tgcactctcc tttcccttaa atgggcacag ccagggtggc tggcatggga ctggcactct
     2041 gtacctccac tccgtcacca gggacagccc cgagggggtg aggagagggg ccttgctctg
     2101 caattcccag agccagatct tcctcatcca agcaataacg ggacgaggga gccagggcca
     2161 aggacactca gggacactgt tggggcagcg gccccacatg gtaatgtttt ctttagagag
     2221 aagaaaaaac aactggctgt aaacgtaaat tatatttctt ggagaaagaa
//
