LOCUS       NM_014045               6892 bp    mRNA    linear   PRI 28-AUG-2024
DEFINITION  Homo sapiens LDL receptor related protein 10 (LRP10), transcript
            variant 1, mRNA.
ACCESSION   NM_014045
VERSION     NM_014045.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6892)
  AUTHORS   Russell,J., Chen,L., Liu,A., Wang,J., Ghosh,S., Zhong,X., Shi,H.,
            Beutler,B. and Nair-Gill,E.
  TITLE     Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and
            anti-tumor immunity
  JOURNAL   EMBO Rep 25 (8), 3601-3626 (2024)
   PUBMED   38956225
  REMARK    GeneRIF: Lrp10 suppresses IL7R limiting CD8 T cell homeostatic
            expansion and anti-tumor immunity.
REFERENCE   2  (bases 1 to 6892)
  AUTHORS   Carreras Mascaro,A., Grochowska,M.M., Boumeester,V., Dits,N.F.J.,
            Bilgi,E.N., Breedveld,G.J., Vergouw,L., de Jong,F.J., van
            Royen,M.E., Bonifati,V. and Mandemakers,W.
  TITLE     LRP10 and alpha-synuclein transmission in Lewy body diseases
  JOURNAL   Cell Mol Life Sci 81 (1), 75 (2024)
   PUBMED   38315424
  REMARK    GeneRIF: LRP10 and alpha-synuclein transmission in Lewy body
            diseases.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6892)
  AUTHORS   Song,N., Wang,Y., Zhou,L., Zhang,J., Wu,F., Li,M., Wang,W., Liu,Y.,
            Lu,X., Chen,Q., Zhang,N., Yan,Y. and Han,F.
  TITLE     Genetic analysis of the LRP10 gene in Chinese patients with
            Parkinson's disease
  JOURNAL   Neurol Sci 44 (3), 905-912 (2023)
   PUBMED   36434476
  REMARK    GeneRIF: Genetic analysis of the LRP10 gene in Chinese patients
            with Parkinson's disease.
REFERENCE   4  (bases 1 to 6892)
  AUTHORS   Liao,T.W., Wang,C.C., Chung,W.H., Su,S.C., Chin,S.H., Fung,H.C. and
            Wu,Y.R.
  TITLE     Role of LRP10 in Parkinson's disease in a Taiwanese cohort
  JOURNAL   Parkinsonism Relat Disord 89, 79-83 (2021)
   PUBMED   34246039
  REMARK    GeneRIF: Role of LRP10 in Parkinson's disease in a Taiwanese
            cohort.
REFERENCE   5  (bases 1 to 6892)
  AUTHORS   Manini,A., Straniero,L., Monfrini,E., Percetti,M., Vizziello,M.,
            Franco,G., Rimoldi,V., Zecchinelli,A., Pezzoli,G., Corti,S.,
            Comi,G.P., Duga,S. and Di Fonzo,A.
  TITLE     Screening of LRP10 mutations in Parkinson's disease patients from
            Italy
  JOURNAL   Parkinsonism Relat Disord 89, 17-21 (2021)
   PUBMED   34216936
  REMARK    GeneRIF: Screening of LRP10 mutations in Parkinson's disease
            patients from Italy.
REFERENCE   6  (bases 1 to 6892)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
REFERENCE   7  (bases 1 to 6892)
  AUTHORS   Wan,D., Gong,Y., Qin,W., Zhang,P., Li,J., Wei,L., Zhou,X., Li,H.,
            Qiu,X., Zhong,F., He,L., Yu,J., Yao,G., Jiang,H., Qian,L., Yu,Y.,
            Shu,H., Chen,X., Xu,H., Guo,M., Pan,Z., Chen,Y., Ge,C., Yang,S. and
            Gu,J.
  TITLE     Large-scale cDNA transfection screening for genes related to cancer
            development and progression
  JOURNAL   Proc Natl Acad Sci U S A 101 (44), 15724-15729 (2004)
   PUBMED   15498874
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2004 Dec 14:101(50):17565]
REFERENCE   8  (bases 1 to 6892)
  AUTHORS   Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
            Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
            Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
            Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
            Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
            Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
            Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
            Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
            Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
REFERENCE   9  (bases 1 to 6892)
  AUTHORS   Tomarev,S.I., Wistow,G., Raymond,V., Dubois,S. and Malyukova,I.
  TITLE     Gene expression profile of the human trabecular meshwork: NEIBank
            sequence tag analysis
  JOURNAL   Invest Ophthalmol Vis Sci 44 (6), 2588-2596 (2003)
   PUBMED   12766061
REFERENCE   10 (bases 1 to 6892)
  AUTHORS   Sugiyama,T., Kumagai,H., Morikawa,Y., Wada,Y., Sugiyama,A.,
            Yasuda,K., Yokoi,N., Tamura,S., Kojima,T., Nosaka,T., Senba,E.,
            Kimura,S., Kadowaki,T., Kodama,T. and Kitamura,T.
  TITLE     A novel low-density lipoprotein receptor-related protein mediating
            cellular uptake of apolipoprotein E-enriched beta-VLDL in vitro
  JOURNAL   Biochemistry 39 (51), 15817-15825 (2000)
   PUBMED   11123907
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL135998.6, AY358399.2,
            BM981286.1, BM846255.1, BQ774170.1, BM997452.1, AI692207.1 and
            AW009640.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_014045.4.
            
            Summary: This gene encodes a low density lipoprotein receptor
            family protein. A similar protein in mouse is thought to play a
            role in the uptake of apolipoprotein E-containing lipoproteins.
            [provided by RefSeq, Jul 2016].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY358399.2, SRR1660809.162905.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000359591.9/ ENSP00000352601.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                AL135998.6         33400-33444         c
            46-3259             AY358399.2         1-3214
            3260-4654           AL135998.6         25709-27103         c
            4655-5119           BM981286.1         149-613             c
            5120-5564           BM846255.1         1-445
            5565-6112           BQ774170.1         93-640              c
            6113-6759           BM997452.1         18-664              c
            6760-6888           AI692207.1         1-129               c
            6889-6892           AW009640.1         20-23               c
FEATURES             Location/Qualifiers
     source          1..6892
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..6892
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /note="LDL receptor related protein 10"
                     /db_xref="GeneID:26020"
                     /db_xref="HGNC:HGNC:14553"
                     /db_xref="MIM:609921"
     exon            1..598
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /inference="alignment:Splign:2.1.0"
     CDS             565..2706
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; low-density lipoprotein receptor-related
                     protein 10"
                     /codon_start=1
                     /product="low-density lipoprotein receptor-related protein
                     10 isoform 1 precursor"
                     /protein_id="NP_054764.2"
                     /db_xref="CCDS:CCDS9578.1"
                     /db_xref="GeneID:26020"
                     /db_xref="HGNC:HGNC:14553"
                     /db_xref="MIM:609921"
                     /translation="MLLATLLLLLLGGALAHPDRIIFPNHACEDPPAVLLEVQGTLQR
                     PLVRDSRTSPANCTWLILGSKEQTVTIRFQKLHLACGSERLTLRSPLQPLISLCEAPP
                     SPLQLPGGNVTITYSYAGARAPMGQGFLLSYSQDWLMCLQEEFQCLNHRCVSAVQRCD
                     GVDACGDGSDEAGCSSDPFPGLTPRPVPSLPCNVTLEDFYGVFSSPGYTHLASVSHPQ
                     SCHWLLDPHDGRRLAVRFTALDLGFGDAVHVYDGPGPPESSRLLRSLTHFSNGKAVTV
                     ETLSGQAVVSYHTVAWSNGRGFNATYHVRGYCLPWDRPCGLGSGLGAGEGLGERCYSE
                     AQRCDGSWDCADGTDEEDCPGCPPGHFPCGAAGTSGATACYLPADRCNYQTFCADGAD
                     ERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCADGSDEWDCSYVLPRKVITAAVIGSL
                     VCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPV
                     EDFPTENPNDNSVLGNLRSLLQILRQDMTPGGGPGARRRQRGRLMRRLVRRLRRWGLL
                     PRTNTPARASEARSQVTPSAAPLEALDGGTGPAREGGAVGGQDGEQAPPLPIKAPLPS
                     ASTSPAPTTVPEAPGPLPSLPLEPSLLSGVVQALRGRLLPSLGPPGPTRSPPGPHTAV
                     LALEDEDDVLLVPLAEPGVWVAEAEDEPLLT"
     exon            599..643
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /inference="alignment:Splign:2.1.0"
     exon            644..779
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /inference="alignment:Splign:2.1.0"
     exon            780..970
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1988
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /inference="alignment:Splign:2.1.0"
     exon            1989..2118
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /inference="alignment:Splign:2.1.0"
     exon            2119..6892
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3239..3244
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /note="hexamer: AATAAA"
     polyA_site      3263
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /note="major polyA site"
     regulatory      6729..6734
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /note="hexamer: TATAAA"
     polyA_site      6759
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
     regulatory      6869..6874
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
                     /note="hexamer: AATAAA"
     polyA_site      6892
                     /gene="LRP10"
                     /gene_synonym="LRP-10; LRP9; MST087; MSTP087"
ORIGIN      
        1 acccgccccg gctactccaa cccctgggcg ggcgggggta ccgcctgggc aagggccggg
       61 gcgccgggcc gagccacctc ttcccctccc ccgcttccct gtcgcgctcc gctggctgga
      121 cgcgctggag gagtggagca gcacccggcc ggccctgggg gctgacagtc ggcaaagttt
      181 ggcccgaaga ggaagtggtc tcaaaccccg gcaggtggcg accaggccag accaggggcg
      241 ctcgctgcct gcgggcgggc tgtaggcgag ggcgcgcccc agtgccgaga cccggggctt
      301 caggagccgg ccccgggaga gaagagtgcg gcggcggacg gagaaaacaa ctccaaagtt
      361 ggcgaaaggc accgccccta ctcccgggct gccgccgcct ccccgccccc agccctggca
      421 tccagagtac gggtcgagcc cgggccatgg agcccccctg gggaggcggc accagggagc
      481 ctgggcgccc ggggctccgc cgcgacccca tcgggtagac cacagaagct ccgggaccct
      541 tccggcacct ctggacagcc caggatgctg ttggccaccc tcctcctcct cctccttgga
      601 ggcgctctgg cccatccaga ccggattatt tttccaaatc atgcttgtga ggacccccca
      661 gcagtgctct tagaagtgca gggcacctta cagaggcccc tggtccggga cagccgcacc
      721 tcccctgcca actgcacctg gctcatcctg ggcagcaagg aacagactgt caccatcagg
      781 ttccagaagc tacacctggc ctgtggctca gagcgcttaa ccctacgctc ccctctccag
      841 ccactgatct ccctgtgtga ggcacctccc agccctctgc agctgcccgg gggcaacgtc
      901 accatcactt acagctatgc tggggccaga gcacccatgg gccagggctt cctgctctcc
      961 tacagccaag attggctgat gtgcctgcag gaagagtttc agtgcctgaa ccaccgctgt
     1021 gtatctgctg tccagcgctg tgatggggtt gatgcctgtg gcgatggctc tgatgaagca
     1081 ggttgcagct cagacccctt ccctggcctg accccaagac ccgtcccctc cctgccttgc
     1141 aatgtcacct tggaggactt ctatggggtc ttctcctctc ctggatatac acacctagcc
     1201 tcagtctccc acccccagtc ctgccattgg ctgctggacc cccatgatgg ccggcggctg
     1261 gccgtgcgct tcacagccct ggacttgggc tttggagatg cagtgcatgt gtatgacggc
     1321 cctgggcccc ctgagagctc ccgactactg cgtagtctca cccacttcag caatggcaag
     1381 gctgtcactg tggagacact gtctggccag gctgttgtgt cctaccacac agttgcttgg
     1441 agcaatggtc gtggcttcaa tgccacctac catgtgcggg gctattgctt gccttgggac
     1501 agaccctgtg gcttaggctc tggcctggga gctggcgaag gcctaggtga gcgctgctac
     1561 agtgaggcac agcgctgtga cggctcatgg gactgtgctg acggcacaga tgaggaggac
     1621 tgcccaggct gcccacctgg acacttcccc tgtggggctg ctggcacctc tggtgccaca
     1681 gcctgctacc tgcctgctga ccgctgcaac taccagactt tctgtgctga tggagcagat
     1741 gagagacgct gtcggcattg ccagcctggc aatttccgat gccgggacga gaagtgcgtg
     1801 tatgagacgt gggtgtgcga tgggcagcca gactgtgcgg acggcagtga tgagtgggac
     1861 tgctcctatg ttctgccccg caaggtcatt acagctgcag tcattggcag cctagtgtgc
     1921 ggcctgctcc tggtcatcgc cctgggctgc acctgcaagc tctatgccat tcgcacccag
     1981 gagtacagca tctttgcccc cctctcccgg atggaggctg agattgtgca gcagcaggca
     2041 cccccttcct acgggcagct cattgcccag ggtgccatcc cacctgtaga agactttcct
     2101 acagagaatc ctaatgataa ctcagtgctg ggcaacctgc gttctctgct acagatctta
     2161 cgccaggata tgactccagg aggtggccca ggtgcccgcc gtcgtcagcg gggccgcttg
     2221 atgcgacgcc tggtacgccg tctccgccgc tggggcttgc tccctcgaac caacaccccg
     2281 gctcgggcct ctgaggccag atcccaggtc acaccttctg ctgctcccct tgaggcccta
     2341 gatggtggca caggtccagc ccgtgagggc ggggcagtgg gtgggcaaga tggggagcag
     2401 gcacccccac tgcccatcaa ggctcccctc ccatctgcta gcacgtctcc agcccccact
     2461 actgtccctg aagccccagg gccactgccc tcactgcccc tagagccatc actattgtct
     2521 ggagtggtgc aggccctgcg aggccgcctg ttgcccagcc tggggccccc aggaccaacc
     2581 cggagccccc ctggacccca cacagcagtc ctggccctgg aagatgagga cgatgtgcta
     2641 ctggtgccac tggctgagcc gggggtgtgg gtagctgagg cagaggatga gccactgctt
     2701 acctgagggg acctgggggc tctactgagg cctctcccct gggggctcta ctcatagtgg
     2761 cacaaccttt tagaggtggg tcagcctccc ctccaccact tccttccctg tccctggatt
     2821 tcagggactt ggtgggcctc ccgttgaccc tatgtagctg ctataaagtt aagtgtccct
     2881 caggcaggga gagggctcac agagtctcct ctgtacgtgg ccatggccag acaccccagt
     2941 cccttcacca ccacctgctc cccacgccac caccatttgg gtggctgttt ttaaaaagta
     3001 aagttcttag aggatcatag gtctggacac tccatccttg ccaaacctct acccaaaagt
     3061 ggccttaagc accggaatgc caattaacta gagaccctcc agcccccaag gggaggattt
     3121 gggcagaacc tgaggttttg ccatccacaa tccctcctac agggcctggc tcacaaaaag
     3181 agtgcaacaa atgcttctat tccatagcta cggcattgct cagtaagttg aggtcaaaaa
     3241 taaaggaatc atacatctca aaattttgca aattagctgc gagcctgagc cccgcctctg
     3301 cccatctcag tctatgctca cctcatccca ctcctccctg tggagccctt tgcttggccc
     3361 tctacctcct gccctcttcc tgttcatctc ccaaccactg cactcttgat ttttatacca
     3421 cacagaaggt aagaaaattc taggaaccct aaggatcaat cctctccatt ttcactcaaa
     3481 tgcctggggc ccagctctgc aatgactgac tccagggcct ctttcctcac tgccagcata
     3541 gaagtcaggg gagccagctg ggccctgcgg tcaggaaggt tctcattttt ggagcatacc
     3601 ctgagcccag atcataggag cagctgtccc tggtgggaca caggagtcat gactcctacc
     3661 ctccaccctc cacacccacc aggcatttag cagtctgtcc tatgcaagac agatgaattc
     3721 tcagccagga tacctcaagg caggcaaagg tgagtggagg gagaattcac aaacattcag
     3781 ggtgtgtggt gctggcatca ccatggccaa atccaagagg tcttcctgga agagggccca
     3841 aactggaacc aaaagaatgc tgtcagcagt tggaatagag ctgtgaattc tagacagggg
     3901 gagtgtcccc agaacaagca aacggaggag acaagagggc aagggttata ggaaagaccc
     3961 tgggcctgag agcacaagca gcggccagag ctgcagcgct ggggtgggtg atggagggaa
     4021 tgattcgcaa gcagtgttgg aacccagccc ctagtgagca aagtgacaga agctgcccca
     4081 gagtttggaa ggaagatcga ggcagaagat gtagaaggaa gctgtggggg tgggagtgat
     4141 gcctcaggaa caaaactgag gaattcccta acggacccag tccctgggga aagaggctcc
     4201 cctcaggctc tccttgtcta gccccacacc tggcagagcc tgtcacccag cctagcccca
     4261 cgcctggcag agcccatcac ccagcctagc cccacacctg gtggagaggc cctgttgatt
     4321 acaccctgtc agcctcctca aacccagcac taattgcaca attttcctct cttctagtga
     4381 gcaagagcct gaggaagtag cagagagggg tgtgggccca tgtgcagttc tgggaccctg
     4441 gcaccttggc tcagggaaga cccgagctcc tttcactgca gaccctctcc agagactggg
     4501 gagagggctc tggagaacct ggttcttgct tactgttctc cctttgggcc ctccttccca
     4561 aacgcaaaca atccaggatc cactcagcgt caggcccaat ggaaatagtg aagcagtgat
     4621 tttccctccc ctgcctctcc atagcctggt cttttgccct ctcctttgct cttctcttcc
     4681 cccatagcca cctcaaatac ctgcagcctg atatcttcat cccttcatcc agaccttttc
     4741 tctcctagtg gtattgcaaa ctgaaagtgg acaaagactt aaggtaaacc tgctcctcat
     4801 ggtggaatgc ttccaaatgc tggaaggagg actttagggc agagttcact aaggaggctt
     4861 gtgcttatag atcagtgggc ctgaaagaag tttctctagg ttctggttgt gtgctgtacg
     4921 aggtgtaggt agtaataata ctcttgtcag ccacagtgaa gccccaagct agccgggata
     4981 ggggactgac cttgtacagg cagcatggag aaactaagac agagtgtcct gcccaagtga
     5041 tggcactggg gagcagtcac tcaggtttat ttccaccagg gcccaagaaa aaaagaaatg
     5101 aggcaaccta aaattccatc aagatagata ccaatatcca aggtgcttgg tcttagcggt
     5161 gtgggaccca cgttaaggct cttggtggga aggtgggagg tgttttcagc atgagatagg
     5221 gttcaggctg tgaatcagag tctagagcct aagataaaag aagataccag ggctgggcca
     5281 cggtggcttt cgcctgtaat cctagcactt tgggaggcca aggcaggcag actgcctgag
     5341 ctcaggagtt cgagactagc ctgagcaaca cggtgaaacc ctgtctctac taaaatacaa
     5401 aaaagtagcc aggtgtggcg gcatgcacct gtagtcccag ctactcgaga ggctgaggca
     5461 ggagaattgc ttgaacccgg gaggcggagg ttgcagtgag tggagatcgc gccactgcac
     5521 tctagcctgg gtgacagagc gagactcctt ctccaaaaaa aaagaaaaga agataccaga
     5581 actcagtcct taagaaacaa aattctgcca ggcgcagtag ctcacacctg taatcccagc
     5641 actttggagg ggccaaggca ggcggatcgc ttgaggccaa gagttcaaga acagcctggg
     5701 caacatgatg aaaccctgtc tctaccaaaa atactaaaaa ttagccagtc tcacaacctg
     5761 gtctcaaaat aaataaatag atttaaaaaa aaaatcatgg gcctgaacca agctccagac
     5821 ctcactagga ggggagaagg accccccagc cacacagccc aaggctgcag aagcacctag
     5881 gtggttagag agtgagtgcc tggatggggc gcagtggctc acacctgtaa tcccagcact
     5941 ttgggaggcc gaggcaggcg gatcacgagg tcaagagatc aagaccatcc tggccaacat
     6001 ggtgacaccg tgtctctact aaaaatacaa aaataagctg ggcatggtgg tgcgtgcctg
     6061 tagtcccatc tactcgggag gctgaagcag gagaatcact tgaacctggg aggcaaaggt
     6121 tgcagtgagc tgagatcgcg ccactgcact ccagcctggc aacagagcga gacaagactc
     6181 catctcaaaa aaaaaagtga gtgcccgatg atgccagatt cttcatcacc tgaagtgaac
     6241 ccacacaaca gggctgggcc atgggcatca taaaccccat tttgcaagct caggaggagc
     6301 tttagggaaa tcagaagact ggcccagtct ctaccaagtg gtggatttag agccggcatg
     6361 gcttcgttcc aaatctcacc cttgtcccac cattccatgg gacctcccat tcctgaggga
     6421 gcctggatac gggcaagtgc acaacccggg aggttgaggt tacagtgagc catgatcgca
     6481 ccactgcagt ccagcccgag caatagggtg agaccctccc tctgaaaaaa ataaaaatac
     6541 tcattttgga aggaagtcat tctaaaatgt tacacttgtc ttcagcatat ctgcaatata
     6601 ataattttct gcataactga ggatcattca cagaaaccaa tggcttttct ccagcagtgt
     6661 cttctgaagt tgtaacagta ggggcacggg gagctatttg cttttatgct aaatgacctt
     6721 agaccactta taaaatgcat atgagtgctt taaatgttat tttgtgtgtg tgtggtgttg
     6781 cctccctgac tacaaggggt cacttgctac tctaaatgtg tttctaatct actagtacag
     6841 gaacacacat ggacacgtta aaattgtgaa taaaagtaag taaaaagtaa aa
//
