LOCUS       NM_001365715            7129 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens leucine rich repeats and calponin homology domain
            containing 3 (LRCH3), transcript variant 3, mRNA.
ACCESSION   NM_001365715 XM_006713791
VERSION     NM_001365715.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7129)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   2  (bases 1 to 7129)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 7129)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 7129)
  AUTHORS   O'Loughlin,T., Masters,T.A. and Buss,F.
  TITLE     The MYO6 interactome reveals adaptor complexes coordinating early
            endosome and cytoskeletal dynamics
  JOURNAL   EMBO Rep 19 (4) (2018)
   PUBMED   29467281
REFERENCE   5  (bases 1 to 7129)
  AUTHORS   Couzens,A.L., Knight,J.D., Kean,M.J., Teo,G., Weiss,A.,
            Dunham,W.H., Lin,Z.Y., Bagshaw,R.D., Sicheri,F., Pawson,T.,
            Wrana,J.L., Choi,H. and Gingras,A.C.
  TITLE     Protein interaction network of the mammalian Hippo pathway reveals
            mechanisms of kinase-phosphatase interactions
  JOURNAL   Sci Signal 6 (302), rs15 (2013)
   PUBMED   24255178
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7129)
  AUTHORS   Foussard,H., Ferrer,P., Valenti,P., Polesello,C., Carreno,S. and
            Payre,F.
  TITLE     LRCH proteins: a novel family of cytoskeletal regulators
  JOURNAL   PLoS One 5 (8), e12257 (2010)
   PUBMED   20805893
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 7129)
  AUTHORS   Jin,J., Smith,F.D., Stark,C., Wells,C.D., Fawcett,J.P.,
            Kulkarni,S., Metalnikov,P., O'Donnell,P., Taylor,P., Taylor,L.,
            Zougman,A., Woodgett,J.R., Langeberg,L.K., Scott,J.D. and Pawson,T.
  TITLE     Proteomic, functional, and domain-based analysis of in vivo 14-3-3
            binding proteins involved in cytoskeletal regulation and cellular
            organization
  JOURNAL   Curr Biol 14 (16), 1436-1450 (2004)
   PUBMED   15324660
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC055764.23, AC144530.11 and AC135893.2.
            
            On Sep 13, 2018 this sequence version replaced XM_006713791.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.270987.1,
                                           DRR138517.141128.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000425562.7/ ENSP00000393579.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-287               AC055764.23        51940-52226         c
            288-432             AC055764.23        28428-28572         c
            433-559             AC055764.23        26178-26304         c
            560-665             AC055764.23        23050-23155         c
            666-802             AC055764.23        16466-16602         c
            803-912             AC055764.23        13807-13916         c
            913-1006            AC055764.23        12617-12710         c
            1007-1127           AC055764.23        11163-11283         c
            1128-1276           AC055764.23        7658-7806           c
            1277-1353           AC055764.23        4083-4159           c
            1354-1405           AC144530.11        5935-5986
            1406-1555           AC144530.11        6398-6547
            1556-1615           AC144530.11        11087-11146
            1616-1669           AC144530.11        12918-12971
            1670-1741           AC144530.11        17360-17431
            1742-1790           AC144530.11        23949-23997
            1791-1898           AC144530.11        24638-24745
            1899-2017           AC144530.11        28686-28804
            2018-2155           AC144530.11        29851-29988
            2156-2233           AC144530.11        34224-34301
            2234-2511           AC144530.11        42067-42344
            2512-7129           AC135893.2         2006-6623
FEATURES             Location/Qualifiers
     source          1..7129
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q29"
     gene            1..7129
                     /gene="LRCH3"
                     /note="leucine rich repeats and calponin homology domain
                     containing 3"
                     /db_xref="GeneID:84859"
                     /db_xref="HGNC:HGNC:28637"
     exon            1..287
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..2359
                     /gene="LRCH3"
                     /note="isoform 3 is encoded by transcript variant 3;
                     leucine-rich repeat and calponin homology
                     domain-containing protein 3; leucine-rich repeats and
                     calponin homology (CH) domain containing 3; DISP complex
                     protein LRCH3"
                     /codon_start=1
                     /product="DISP complex protein LRCH3 isoform 3"
                     /protein_id="NP_001352644.1"
                     /db_xref="CCDS:CCDS93456.1"
                     /db_xref="GeneID:84859"
                     /db_xref="HGNC:HGNC:28637"
                     /translation="MAAAGLVAVAAAAEYSGTVASGGNLPGVHCGPSSGAGPGFGPGS
                     WSRSLDRALEEAAVTGVLSLSGRKLREFPRGAANHDLTDTTRADLSRNRLSEIPIEAC
                     HFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLPLKVLIASNN
                     KLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAEL
                     PLIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQICIKGKVHIFKYLNIQA
                     CKIAPDLPDYDRRPLGFGSCHEELYSSRPYGALDSGFNSVDSGDKRWSGNEPTDEFSD
                     LPLRVAEITKEQRLRRESQYQENRGSLVVTNGGVEHDLDQIDYIDSCTAEEEEAEVRQ
                     PKGPDPDSLSSQFMAYIEQRRISHEGSPVKPVAIREFQKTEDMRRYLHQNRVPAEPSS
                     LLSLSASHNQLSHTDLELHQRREQLVERTRREAQLAALQYEEEKIRTKQIQRDAVLDF
                     VKQKASQSPQKQHPLLDGVDGECPFPSRRSQHTDDSALCMSLSGLNQVGCAATLPHSS
                     AFTPLKSDDRPNALLSSPATETVHHSPAYSFPAAIQRNQPQRPESFLFRAGVRAETNK
                     GHASPLPPSAAPTTDSTDSITGQNSRQREEELELIDQLRKHIEYRLKVSLPCDLGAAL
                     TDGVVLCHLANHVRPRSVPSIHVPSPAVPKLTMAKCRRNVENFLEACRKIGVPQEQLC
                     LPLHILEEKGLSQVAVTVQALLELAPPKQQQHQLSAV"
     exon            288..432
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            433..559
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            560..665
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            666..802
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            803..912
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1006
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1127
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1276
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1353
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..1405
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1555
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1615
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1669
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1670..1741
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1790
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..1898
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            1899..2017
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            2018..2155
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2233
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     exon            2234..7129
                     /gene="LRCH3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4505..4510
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRCH3"
                     /note="hexamer: AATAAA"
     polyA_site      4524
                     /gene="LRCH3"
                     /note="major polyA site"
     regulatory      7095..7100
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRCH3"
                     /note="hexamer: AATAAA"
     polyA_site      7129
                     /gene="LRCH3"
                     /note="major polyA site"
ORIGIN      
        1 gggcccgagt gttgtcggct gggaaatggc ggccgcgggc ttggtcgctg tggcagcggc
       61 tgccgagtac tctggcacgg tagcgtcggg aggtaacctc cctggtgttc actgcggccc
      121 aagctccggg gcaggccctg gttttggccc gggctcgtgg agccgctctc tcgatcgagc
      181 cctggaggag gcggcggtca ctggggtgct gagcctgagc ggccggaaac tgagggagtt
      241 tccccgggga gcggccaacc acgacctgac ggacaccacc cgggcggacc tgtcgcgaaa
      301 tcgcctttca gaaattccta tagaagcatg tcactttgtt tctctggaaa atctcaactt
      361 gtaccaaaat tgtattcgtt atattccaga ggcaatttta aacctacaag ctctaacatt
      421 cttaaatatt agtcggaacc aactgtcaac attgccggta cacttgtgta atttgccatt
      481 gaaagtctta attgctagta ataacaaatt ggtgtcactt ccagaagaaa ttggacacct
      541 tagacatttg atggaacttg atgtgagctg caatgaaatt caaactatac cttcccaaat
      601 tggtaacctg gaggccttga gagaccttaa tgtaagaaga aatcacctag tacatttgcc
      661 tgaagagctg gcggagttgc ctttgatacg gttagacttc tcatgcaata aaattaccac
      721 aatccctgtt tgttatcgga acctcaggca cctacagacg atcaccctag ataacaatcc
      781 actacaatca cctcctgcac agatatgtat aaaaggcaaa gtccacatat ttaaatacct
      841 gaacatacaa gcttgtaaga ttgctccaga tctgccggat tatgatagga gaccgttggg
      901 ttttggctcc tgccatgaag aactgtactc aagtcgccct tatggagccc ttgattcagg
      961 cttcaatagt gtggacagtg gtgataagag atggtcaggg aatgaaccta cagatgaatt
     1021 ttcagatctg cctcttcgag tagcagagat tactaaagaa caaagactac gaagagaaag
     1081 ccagtaccaa gagaaccgcg gcagtttggt agtaacaaac ggcggagtgg aacatgatct
     1141 ggatcagatt gactacatag acagctgcac cgcagaggaa gaggaggccg aggtgagaca
     1201 gcccaaggga ccagacccag acagccttag ttcacagttt atggcgtata ttgaacagcg
     1261 gcgaatctct catgagggtt caccagtaaa gccagtagcc attagggagt ttcaaaaaac
     1321 agaagatatg agaagatatt tacatcaaaa cagggttcca gctgagccat cttccctcct
     1381 gtcactatca gcaagtcaca atcagctgtc acacacagac ctggaacttc atcagagaag
     1441 ggagcagtta gtagagcgca ctcggagaga ggctcagctt gctgccctgc agtatgagga
     1501 ggagaaaata aggaccaagc agatccagag agatgctgtc ctggactttg tcaaacaaaa
     1561 agcatcacaa agtccacaaa aacagcaccc gctcctagat ggcgtagatg gtgagtgccc
     1621 cttcccatcc agaaggtctc agcacactga tgatagtgcc ttgtgcatgt cgctgtcagg
     1681 gttgaatcaa gtgggctgtg ctgctaccct gcctcattct tctgccttca cgcctcttaa
     1741 gagtgatgac agacctaatg ctctattaag ttcacctgca acagaaacag ttcatcattc
     1801 ccctgcatat tcttttcctg ctgctatcca gagaaatcag cctcagcgcc ctgaaagctt
     1861 ccttttccga gcaggtgtca gggcagaaac caacaaaggt catgcttcac cccttcctcc
     1921 atctgctgca cctaccactg attctacaga ttccataaca ggacagaatt caagacagag
     1981 agaagaagag ctggaattaa tagaccaact gcgtaaacat attgagtacc ggttgaaagt
     2041 gtctctacct tgtgatctcg gagcagctct aactgacggt gttgttcttt gccatttggc
     2101 caatcatgtg cgacctcgat ctgtcccaag cattcatgtt ccctcaccag ctgtacctaa
     2161 attaacaatg gcgaaatgca ggcgaaatgt ggaaaatttc ctagaagctt gcagaaaaat
     2221 tggtgtacct caggagcaat tatgtttgcc tctccacatt ttagaagaga aaggtttgag
     2281 ccaggttgca gtgacggtcc aggctctcct ggaacttgcc ccacccaagc aacagcagca
     2341 ccagttatct gctgtttgag gatccccagg acggtgggca ctggcctggc caaaacaagg
     2401 aacaggacac cgtgattgct gctgccagct gtctgcttaa acaaagctct tgtgtgttct
     2461 cagaagggac cgttcccatg attcctaaca ggaatatttt gcttcatttc tccattttag
     2521 gggaggttat ttccatttcc attgaatttt tttacgaaga caccattggt tttctcagat
     2581 gaaacttctc ttactgaaaa cccagcacct aacttggctg tgttttcctg gagagcaggc
     2641 gtgtttcacg tgccagaaag cacatcttct gtgttaggca caagcatgct gtgccattgt
     2701 ttttacctgg tctcaagaca actggtctgc tggtttctaa acttggttgt tcattagact
     2761 ctcctggagt atttgttaaa atacagattc acattcagta gagctggggt aaggcctagg
     2821 aatctgcatt ttcaacaacc attgcacatg tttttgtttt tgttggagaa ggagttctgc
     2881 tcagtcgccc aggctagagt gcagtggcat aatctcagct cactgcaacc tccgcctccc
     2941 gggctcaagc gattctcctg cctcagcctc ccgagtagct gggacaacag gtgcccgcca
     3001 ccatgcctgg ctaattttct tgtattttta gtagagatgg gattttgtca tgttggccag
     3061 gctggtctca aactcctgac ttcaagtgat ccacctgcct cggcctccca aaatgctggg
     3121 attacaggcg tgagccactg tgcccggcct cccagagtgc tgggatgaca ggcgtgagcc
     3181 cccgcgcccg gcctccgaga gtgctgggat tacaggcgtg agccactgtg cccggcctct
     3241 gagggtgctg ggattacagg cgtgagccac tgcgcccggc gcccggccca ttgcacgtgt
     3301 ttttcatgta gtggaaccac tgttcaaagc tagatatttg tatgtttgcg ggggagggta
     3361 atggccccct gcatttttca cccacattta aaatcaaaag ctatattatg aggagttgga
     3421 ctgttctgtc aaaggcaaaa caaaaataat atagaaggcc taggttttgc atagtcttct
     3481 tttttttaag agttggggtc ttgccgtatt gcccaggctg gtctgaaact cctgggctca
     3541 actgatcctc ccgcctcagc ctcccaaagt gctgggatta ctggagtgag ccatcgggcc
     3601 tggcccagat tttgcatagt aaaacagtga aacagataga gttgtattta aggtcagtat
     3661 tctaggcctc ccttcaactg cagtcatacc atcatagaag atagttctat gtcatcctgt
     3721 tatctggaca ttataataaa caacaagccc tctatacaca ggttccaaac cccgttatct
     3781 agacattatc aacaacaagc cctctctcta tacagagttt ccaaattctg aagctgatag
     3841 cgcacttggt ctcactgagc ctccctcccc gccctcctgc tgctcctcag acatctgggc
     3901 ctgcagacac attgcagtta cagcacatac acttctagct cggaaaagcc tagtttcttg
     3961 tatttctttc aggtaactgc cagtttctgt ggctgaattt aagcacttac agcatcttcc
     4021 tagctgggtg tggtggctca cacctgtaat ctcagcactt tgggaggctg aggcgggcag
     4081 atcacctgaa gttgggagtt tgagaccagc ctgaccaaca tggagaaacc ccgtctctac
     4141 taaaaataca aaattagctg ggcgtggtgg tgcatgcctg taatcccagc tactcgggag
     4201 gctgaggcag gagaattgct tgaacccagg aggcggaggt tgtggtgagc caagatcgtg
     4261 ccattgcacc ccagcctggg caacaaaagc gaaattccat ctcaaaaaaa gaaaacgcgc
     4321 cccatctcgc tccaccacaa gcgcctttat atactcaatg atgggtggag gaaaagggcc
     4381 caagggctca caccgcacag gagcctttac tcaagtttca gctagttttc cttcccctgc
     4441 attttgaact ccttttagtt gttggtgata tcctttggtg ttcactgcct ttgtaaaaca
     4501 agtaaataaa gtaagcggaa gatatctctt ttgtttctgt agttgttaac tgttctggat
     4561 tttctttaca atgcatccat ttgggcataa tgttatccct ctttttatca ggtaaatgta
     4621 gcatctaaaa gtagctttgg atcaaatcat gttgaatacc tggtcaaagt aatgttttct
     4681 tccttgttct tgcagagaaa caaattcatc agaacattac cacttgacca ggtttaaaat
     4741 tgtataacag gctgggcatg gtggctcatg cctataatcc cagcactttg ggaggccgag
     4801 gcaagaggat cacttgagcc caggagtttg agagcagcct gggcaacata gcaagaccct
     4861 gtctcccaaa aattaaaaaa aaaaaaaaaa aaccaggtgt ggtggcacct gcctgtactc
     4921 ccagctactc aggaggctgg ggtgggagga tcacttgagc ctgggaggtt gaggctacag
     4981 tgagccatgg ctgcaccact gcactccagc ctgggcaaca gagtgagacc ccatctctaa
     5041 aaataaattg tacaacatct aacttcaatg cccaatctta tagaacaaaa gtaaaatgtc
     5101 tttatgtaag accccattat atttacagtt cccaacagac ccaccaactc ttatataccc
     5161 ttatataact tgtttagaat ttagccatgt gcatttttaa actgtgtttg tcaacattaa
     5221 gcctcagtac agtctccaaa ttatatgcca ccagaaatga aattcagcaa aggacaggat
     5281 tgtttttaac atacgcaagc cagcctggcc aacatggtga aaccttgtct ctactaaaaa
     5341 tacaaaaatt agctgggcgt ggtggtgggc acctgtaatc ccagctactt gggtggctga
     5401 ggcacaagaa tcgcttcaac ctggaagccg aaggttgcag tgggctgaga ttgtgccact
     5461 gcactccagc ctgggcaaca gagcgagact ctgtctcaaa aaaaaaaaaa aaaaaaaacc
     5521 caccaaacca aaaatatact atgcaaggaa taattctaga agacattaca taatgcaata
     5581 cttgcaacat ttgcaactaa ttttcccata gggataaatg gaaatttcaa cttatttcaa
     5641 attttgcaca tattatgaaa ccttattaat gtatttttat caaactaaat cagatttgta
     5701 tttgaattgt taggaaaaac catgtgcagt tttggctgat aattgaagga aaaatatcaa
     5761 atgctttgaa ttttttttct cttttttcaa accctctgca gaggtaggaa ggtatgaatt
     5821 tcttttttat gtcaagatgc aaaaacaaat catgatgctt ttgttgggag aatttttgta
     5881 ttcagtattt tgtatgtacc tttttttttt taaattggaa agcacaattc ggtttaacat
     5941 ttagctttgc ttgactccag tgtaagatga agatgacctt gtcacagctc ccctgacctg
     6001 aagcagagcc cttcccatca ctgacagtgt tgggggttga gagcccccca gcagagccct
     6061 tcccatcact gacagtgtgt cggcagctga gagctccccc agcagagccc ttcccatcac
     6121 tgaacagtgt tggcggctga gagcccccca gcagagccct tcccatcact gacagtgttg
     6181 ggggctgaga gccccccagc agagcccttc ccatcactga acagtgttgg cggctgagag
     6241 ccccccagca gagcccttcc catcactgac agtgttgggg gctgagagcc cccctagcag
     6301 agcccttccc atcactgaca gtgtctgggg ctgagagccc cccctagcag agcccttccc
     6361 atcactgaca gtgttggggg ctgagagccc cccagcagag cccttcccat cactgacagt
     6421 gtctggggct gagagccccc cagcagagcc cttcccatca ctgacagtgt ctggggctga
     6481 gagccccccc tagcagagcc cttcccatca ctgacagtgt cgggttgaga gccaccccca
     6541 gcagagccct tgccacgtac agagattttc tgtcagcagt ttcccagtat ttcagactca
     6601 taatctgtgt ttagcactcc agtgttctct tgtaatagcc aggtctggaa acgacccatg
     6661 gaaagagggg cctttgtatt ctgctagaac acagagcata gtagtagatc acttttctga
     6721 agagcttttt aaaatacagc taatcaagga gtttgcgatt tctcttactt tctacagctc
     6781 agcagtgact aatgatgtgt gactatgcga atgagtttga tgaattcgta aaaactaagc
     6841 gcttaaatgg ttatagaaat gaaaacatgg atatttagaa gcctttctat atacacagtg
     6901 cagttgagat ggtttacagc aaatttcgtt ttatttctga aaatgttgta aacatgtaat
     6961 tagtgaaaga ttttgtaaaa cattgtcctg tatttttgtc tgtaaatata ttgcataagt
     7021 tctaagtata aatatgtcag tatcatgtat gttattttaa attgcctgta cgccacttta
     7081 cacattgaca ttcaaataaa agccaacact tcagtggcgt gtaataaaa
//
