LOCUS       NM_001364905           10148 bp    mRNA    linear   PRI 08-OCT-2024
DEFINITION  Homo sapiens LPS responsive beige-like anchor protein (LRBA),
            transcript variant 3, mRNA.
ACCESSION   NM_001364905 XM_005263375
VERSION     NM_001364905.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10148)
  AUTHORS   Szentgyorgyi,V., Lueck,L.M., Overwijn,D., Ritz,D., Zoeller,N.,
            Schmidt,A., Hondele,M., Spang,A. and Bakhtiar,S.
  TITLE     Arf1-dependent LRBA recruitment to Rab4 endosomes is required for
            endolysosome homeostasis
  JOURNAL   J Cell Biol 223 (11) (2024)
   PUBMED   39325073
  REMARK    GeneRIF: Arf1-dependent LRBA recruitment to Rab4 endosomes is
            required for endolysosome homeostasis.
REFERENCE   2  (bases 1 to 10148)
  AUTHORS   Freund,T., Baxter,S.K., Walsh,T., Golan,H., Kapelushnik,J.,
            Abramsohn-Goldenberg,M., Benor,S., Sarid,N., Ram,R., Alcalay,Y.,
            Segel,R., Renbaum,P., Stepensky,P., King,M.C., Torgerson,T.R. and
            Hagin,D.
  TITLE     Clinically Complex LRBA Deficiency Due to a Founder Allele in the
            Georgian Jewish Population
  JOURNAL   J Clin Immunol 43 (1), 151-164 (2023)
   PUBMED   36063261
  REMARK    GeneRIF: Clinically Complex LRBA Deficiency Due to a Founder Allele
            in the Georgian Jewish Population.
REFERENCE   3  (bases 1 to 10148)
  AUTHORS   Catak,M.C., Akcam,B., Bilgic Eltan,S., Babayeva,R., Karakus,I.S.,
            Akgun,G., Baser,D., Bulutoglu,A., Bayram,F., Kasap,N., Kiykim,A.,
            Hancioglu,G., Kokcu Karadag,S.I., Kendir Demirkol,Y., Ozen,S.,
            Cekic,S., Ozcan,D., Edeer Karaca,N., Sasihuseyinoglu,A.S.,
            Cansever,M., Ozek Yucel,E., Tamay,Z., Altintas,D.U., Aydogmus,C.,
            Celmeli,F., Cokugras,H., Gulez,N., Genel,F., Metin,A., Guner,S.N.,
            Kutukculer,N., Keles,S., Reisli,I., Kilic,S.S., Yildiran,A.,
            Karakoc-Aydiner,E., Lo,B., Ozen,A. and Baris,S.
  TITLE     Comparing the levels of CTLA-4-dependent biological defects in
            patients with LRBA deficiency and CTLA-4 insufficiency
  JOURNAL   Allergy 77 (10), 3108-3123 (2022)
   PUBMED   35491430
  REMARK    GeneRIF: Comparing the levels of CTLA-4-dependent biological
            defects in patients with LRBA deficiency and CTLA-4 insufficiency.
REFERENCE   4  (bases 1 to 10148)
  AUTHORS   Yao,J., Gu,H., Mou,W., Chen,Z., Ma,J., Ma,H., Li,N., Zhang,R.,
            Wang,T., Jiang,J. and Wu,R.
  TITLE     Various phenotypes of LRBA gene with compound heterozygous
            variation: A case series report of pediatric cytopenia patients
  JOURNAL   Int J Immunopathol Pharmacol 36, 3946320221125591 (2022)
   PUBMED   36074705
  REMARK    GeneRIF: Various phenotypes of LRBA gene with compound heterozygous
            variation: A case series report of pediatric cytopenia patients.
REFERENCE   5  (bases 1 to 10148)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (bases 1 to 10148)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   7  (bases 1 to 10148)
  AUTHORS   Gebauer,D., Li,J., Jogl,G., Shen,Y., Myszka,D.G. and Tong,L.
  TITLE     Crystal structure of the PH-BEACH domains of human LRBA/BGL
  JOURNAL   Biochemistry 43 (47), 14873-14880 (2004)
   PUBMED   15554694
  REMARK    GeneRIF: The crystal structure of the aPH-BEACH domains of LRBA
            were studied.
REFERENCE   8  (bases 1 to 10148)
  AUTHORS   Dyomin,V.G., Chaganti,S.R., Dyomina,K., Palanisamy,N., Murty,V.V.,
            Dalla-Favera,R. and Chaganti,R.S.
  TITLE     BCL8 is a novel, evolutionarily conserved human gene family
            encoding proteins with presumptive protein kinase A anchoring
            function
  JOURNAL   Genomics 80 (2), 158-165 (2002)
   PUBMED   12160729
REFERENCE   9  (bases 1 to 10148)
  AUTHORS   Wang,J.W., Howson,J., Haller,E. and Kerr,W.G.
  TITLE     Identification of a novel lipopolysaccharide-inducible gene with
            key features of both A kinase anchor proteins and chs1/beige
            proteins
  JOURNAL   J Immunol 166 (7), 4586-4595 (2001)
   PUBMED   11254716
REFERENCE   10 (bases 1 to 10148)
  AUTHORS   Feuchter,A.E., Freeman,J.D. and Mager,D.L.
  TITLE     Strategy for detecting cellular transcripts promoted by human
            endogenous long terminal repeats: identification of a novel gene
            (CDC4L) with homology to yeast CDC4
  JOURNAL   Genomics 13 (4), 1237-1246 (1992)
   PUBMED   1505956
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC104796.4, AC092544.4,
            AC110813.4, AC097373.3, AC092612.3 and AC093748.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jul 13, 2018 this sequence version replaced XM_005263375.3.
            
            Summary: The protein encoded by this gene is a member of the
            WDL-BEACH-WD (WBW) gene family. Its expression is induced in B
            cells and macrophages by bacterial lipopolysaccharides (LPS). The
            encoded protein associates with protein kinase A and may be
            involved in leading intracellular vesicles to activated receptor
            complexes, which aids in the secretion and/or membrane deposition
            of immune effector molecules. Defects in this gene are associated
            with the disorder common variable immunodeficiency-8 with
            autoimmunity. Two transcript variants encoding different isoforms
            have been found for this gene. [provided by RefSeq, Dec 2012].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000651943.2/ ENSP00000498582.2
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                AC104796.4         166619-166701       c
            84-518              AC104796.4         165844-166278       c
            519-750             AC104796.4         80251-80482         c
            751-851             AC104796.4         79933-80033         c
            852-947             AC104796.4         72615-72710         c
            948-1069            AC104796.4         68034-68155         c
            1070-1196           AC104796.4         67818-67944         c
            1197-1316           AC104796.4         67025-67144         c
            1317-1463           AC104796.4         65612-65758         c
            1464-1661           AC104796.4         60077-60274         c
            1662-1795           AC104796.4         59751-59884         c
            1796-1904           AC104796.4         57714-57822         c
            1905-2057           AC104796.4         57255-57407         c
            2058-2226           AC104796.4         51466-51634         c
            2227-2306           AC104796.4         49156-49235         c
            2307-2369           AC104796.4         47811-47873         c
            2370-2467           AC104796.4         44469-44566         c
            2468-2560           AC104796.4         24080-24172         c
            2561-2669           AC104796.4         22762-22870         c
            2670-2751           AC104796.4         21942-22023         c
            2752-2875           AC104796.4         19599-19722         c
            2876-3068           AC104796.4         19088-19280         c
            3069-4127           AC104796.4         3302-4360           c
            4128-4306           AC104796.4         2141-2319           c
            4307-4460           AC104796.4         839-992             c
            4461-4641           AC104796.4         235-415             c
            4642-4763           AC092544.4         153339-153460       c
            4764-4871           AC092544.4         152781-152888       c
            4872-5031           AC092544.4         140498-140657       c
            5032-5473           AC092544.4         136861-137302       c
            5474-5607           AC092544.4         125805-125938       c
            5608-5686           AC092544.4         117001-117079       c
            5687-5820           AC092544.4         114952-115085       c
            5821-5882           AC092544.4         106762-106823       c
            5883-5947           AC092544.4         70464-70528         c
            5948-6056           AC092544.4         43939-44047         c
            6057-6223           AC110813.4         107399-107565       c
            6224-6348           AC110813.4         22855-22979         c
            6349-6495           AC110813.4         14561-14707         c
            6496-6632           AC110813.4         11896-12032         c
            6633-6750           AC097373.3         58346-58463         c
            6751-6853           AC097373.3         55160-55262         c
            6854-6969           AC097373.3         39052-39167         c
            6970-7082           AC097373.3         35101-35213         c
            7083-7223           AC097373.3         4152-4292           c
            7224-7343           AC097373.3         3017-3136           c
            7344-7496           AC092612.3         126572-126724       c
            7497-7664           AC092612.3         61126-61293         c
            7665-7754           AC092612.3         36943-37032         c
            7755-7932           AC092612.3         32325-32502         c
            7933-7995           AC092612.3         26695-26757         c
            7996-8151           AC092612.3         21363-21518         c
            8152-8319           AC092612.3         13759-13926         c
            8320-8421           AC093748.3         107693-107794       c
            8422-8618           AC093748.3         104210-104406       c
            8619-8770           AC093748.3         99613-99764         c
            8771-10148          AC093748.3         86195-87572         c
FEATURES             Location/Qualifiers
     source          1..10148
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q31.3"
     gene            1..10148
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /note="LPS responsive beige-like anchor protein"
                     /db_xref="GeneID:987"
                     /db_xref="HGNC:HGNC:1742"
                     /db_xref="MIM:606453"
     exon            1..83
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            84..518
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     CDS             303..8861
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /note="isoform 3 is encoded by transcript variant 3;
                     vesicle trafficking, beach and anchor containing;
                     lipopolysaccharide-responsive and beige-like anchor
                     protein; CDC4-like protein; LPS-responsive vesicle
                     trafficking, beach and anchor containing"
                     /codon_start=1
                     /product="lipopolysaccharide-responsive and beige-like
                     anchor protein isoform 3"
                     /protein_id="NP_001351834.1"
                     /db_xref="CCDS:CCDS93649.1"
                     /db_xref="GeneID:987"
                     /db_xref="HGNC:HGNC:1742"
                     /db_xref="MIM:606453"
                     /translation="MASEDNRVPSPPPTGDDGGGGGREETPTEGGALSLKPGLPIRGI
                     RMKFAVLTGLVEVGEVSNRDIVETVFNLLVGGQFDLEMNFIIQEGESINCMVDLLEKC
                     DITCQAEVWSMFTAILKKSIRNLQVCTEVGLVEKVLGKIEKVDNMIADLLVDMLGVLA
                     SYNLTVRELKLFFSKLQGDKGRWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIA
                     LPPIAKWPYQNGFTFHTWLRMDPVNNINVDKDKPYLYCFRTSKGLGYSAHFVGGCLIV
                     TSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIYNRWKNSELRCYVNGELASYGEITWFV
                     NTSDTFDKCFLGSSETADANRVFCGQMTAVYLFSEALNAAQIFAIYQLGLGYKGTFKF
                     KAESDLFLAEHHKLLLYDGKLSSAIAFTYNPRATDAQLCLESSPKDNPSIFVHSPHAL
                     MLQDVKAVLTHSIQSAMHSIGGVQVLFPLFAQLDYRQYLSDEIDLTICSTLLAFIMEL
                     LKNSIAMQEQMLACKGFLVIGYSLEKSSKSHVSRAVLELCLAFSKYLSNLQNGMPLLK
                     QLCDHVLLNPAIWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYY
                     YWAVNPQDRSGITPKGLDGPRPNQKEMLSLRAFLLMFIKQLVMKDSGVKEDELQAILN
                     YLLTMHEDDNLMDVLQLLVALMSEHPNSMIPAFDQRNGLRVIYKLLASKSEGIRVQAL
                     KAMGYFLKHLAPKRKAEVMLGHGLFSLLAERLMLQTNLITMTTYNVLFEILIEQIGTQ
                     VIHKQHPDPDSSVKIQNPQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSREN
                     RRSLLQCSVWQEWMLSLCYFNPKNSDEQKITEMVYAIFRILLYHAVKYEWGGWRVWVD
                     TLSITHSKVTFEIHKENLANIFREQQGKVDEEIGLCSSTSVQAASGIRRDINVSVGSQ
                     QPDTKDSPVCPHFTTNGNENSSIEKTSSLESASNIELQTTNTSYEEMKAEQENQELPD
                     EGTLEETLTNETRNADDLEVSSDIIEAVAISSNSFITTGKDSMTVSEVTASISSPSEE
                     DASEMPEFLDKSIVEEEEDDDYVELKVEGSPTEEANLPTELQDNSLSPAASEAGEKLD
                     MFGNDDKLIFQEGKPVTEKQTDTETQDSKDSGIQTMTASGSSAMSPETTVSQIAVESD
                     LGQMLEEGKKATNLTRETKLINDCHGSVSEASSEQKIAKLDVSNVATDTERLELKASP
                     NVEAPQPHRHVLEISRQHEQPGQGIAPDAVNGQRRDSRSTVFRIPEFNWSQMHQRLLT
                     DLLFSIETDIQMWRSHSTKTVMDFVNSSDNVIFVHNTIHLISQVMDNMVMACGGILPL
                     LSAATSATHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKSMSS
                     GGILRQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSLIPLGKSAAKSPVDIVT
                     GGISPVRDLDRLLQDMDINRLRAVVFRDIEDSKQAQFLALAVVYFISVLMVSKYRDIL
                     EPQNERHSQSCTETGSENENVSLSEITPAAFSTLTTASVEESESTSSARRRDSGIGEE
                     TATGLGSHVEVTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATP
                     SVSVSKNVNVKDILRSLVNIPADGVTVDPALLPPACLGALGDLSVEQPVQFRSFDRSV
                     IVAAKKSAVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPGSRSSNAKLPSVPTVD
                     SVSQDPVSNMSITERLEHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLV
                     CMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKDHLVRVANEAE
                     FILSRQRAEDIHRHAEFESLCAQYSADKREDEKMCDHLIRAAKYRDHVTATQLIQKII
                     NILTDKHGAWGNSAVSRPLEFWRLDYWEDDLRRRRRFVRNPLGSTHPEATLKTAVEHA
                     TDEDILAKGKQSIRSQALGNQNSENEILLEGDDDTLSSVDEKDLENLAGPVSLSTPAQ
                     LVAPSVVVKGTLSVTSSELYFEVDEEDPNFKKIDPKILAYTEGLHGKWLFTEIRSIFS
                     RRYLLQNTALEIFMANRVAVMFNFPDPATVKKVVNYLPRVGVGTSFGLPQTRRISLAS
                     PRQLFKASNMTQRWQHREISNFEYLMFLNTIAGRSYNDLNQYPVFPWVITNYESEELD
                     LTLPTNFRDLSKPIGALNPKRAAFFAERYESWEDDQVPKFHYGTHYSTASFVLAWLLR
                     IEPFTTYFLNLQGGKFDHADRTFSSISRAWRNSQRDTSDIKELIPEFYYLPEMFVNFN
                     NYNLGVMDDGTVVSDVELPPWAKTSEEFVHINRLALESEFVSCQLHQWIDLIFGYKQQ
                     GPEAVRALNVFYYLTYEGAVNLNSITDPVLREAVEAQIRSFGQTPSQLLIEPHPPRGS
                     AMQVSPLMFTDKAQQDVIMVLKFPSNSPVTHVAANTQPGLATPAVITVTANRLFAVNK
                     WHNLPAHQGAVQDQPYQLPVEIDPLIASNTGMHRRQITDLLDQSIQVHSQCFVITSDN
                     RYILVCGFWDKSFRVYSTDTGRLIQVVFGHWDVVTCLARSESYIGGNCYILSGSRDAT
                     LLLWYWNGKCSGIGDNPGSETAAPRAILTGHDYEVTCAAVCAELGLVLSGSQEGPCLI
                     HSMNGDLLRTLEGPENCLKPKLIQASREGHCVIFYENGLFCTFSVNGKLQATMETDDN
                     IRAIQLSRDGQYLLTGGDRGVVVVRQVSDLKQLFAYPGCDAGIRAMALSYDQRCIISG
                     MASGSIVLFYNDFNRWHHEYQTRY"
     exon            519..750
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            751..851
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            852..947
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1069
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1196
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1316
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1463
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            1464..1661
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1795
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            1796..1904
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            1905..2057
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2226
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            2227..2306
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            2307..2369
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            2370..2467
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            2468..2560
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            2561..2669
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            2670..2751
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            2752..2875
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            2876..3068
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            3069..4127
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            4128..4306
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            4307..4460
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            4461..4641
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            4642..4763
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            4764..4871
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            4872..5031
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            5032..5473
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            5474..5607
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            5608..5686
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            5687..5820
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            5821..5882
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            5883..5947
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            5948..6056
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            6057..6223
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            6224..6348
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            6349..6495
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            6496..6632
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            6633..6750
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            6751..6853
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            6854..6969
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            6970..7082
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            7083..7223
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            7224..7343
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            7344..7496
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            7497..7664
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            7665..7754
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            7755..7932
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            7933..7995
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            7996..8151
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            8152..8319
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            8320..8421
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            8422..8618
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            8619..8770
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     exon            8771..10148
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9901..9906
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /note="hexamer: AATAAA"
     polyA_site      9924
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /note="major polyA site"
     regulatory      10045..10050
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /note="hexamer: AATAAA"
     polyA_site      10068
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
     regulatory      10112..10117
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /note="hexamer: AATAAA"
     regulatory      10131..10136
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
                     /note="hexamer: AAGAAA"
     polyA_site      10132
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
     polyA_site      10148
                     /gene="LRBA"
                     /gene_synonym="BGL; CDC4L; CVID8; LAB300; LBA; uc.147"
ORIGIN      
        1 gccttttcct gccctggatc tccgccgcca cctcggtctc gctgctcctg ggcggggggt
       61 gaggacgagt ccggagtatc tggggtttgg cgttgttgtc agcctcgggg agagagattg
      121 gacaaatatt ctccaagagg aggagggcga cgccaaggac tttccacatc aactgctttg
      181 gggtatctcc acaagttgga agagggaccc tttcgttttg cattgcgtgt gttgtgctca
      241 ttaccagtgc agcgactgcc gtcccagggt gactctgagt tgtcctttat cgtgagctag
      301 caatggctag cgaagacaat cgtgtccctt ccccgccacc aacaggtgat gacgggggag
      361 gtggagggag agaagaaacc cctactgaag ggggtgcatt gtctctgaaa ccagggctcc
      421 ccatcagggg catcagaatg aaatttgccg tgttgaccgg tttggttgaa gttggagaag
      481 tatccaatag ggatattgta gaaactgtct ttaacctgtt ggtaggagga cagtttgatc
      541 tggaaatgaa tttcattatc caagaaggtg agagtattaa ctgcatggtg gacctactgg
      601 aaaaatgtga cattacgtgc caagcagaag tctggagcat gtttacagcc attctgaaga
      661 aaagcatacg gaatcttcaa gtctgcactg aagtaggcct tgttgaaaaa gtgcttggga
      721 aaattgaaaa agttgacaat atgatagcag atcttttggt tgacatgttg ggagtgctgg
      781 ctagctataa tttgacagtt cgcgagctaa agcttttctt cagtaaactt caaggagata
      841 aaggacgatg gcctccacat gctgggaagt tgctgtctgt gttaaagcat atgcctcaga
      901 agtatggtcc tgatgccttt tttaactttc caggaaagag tgctgcagct attgcattac
      961 ctcctatagc caaatggcca taccagaatg gttttacatt tcatacatgg cttagaatgg
     1021 atcctgtaaa taacatcaat gtagataagg ataaaccata tttgtattgt ttcagaacca
     1081 gcaaaggtct tggctattct gctcattttg ttggaggctg tttgattgta acatcaataa
     1141 agtcaaaagg aaaaggcttt caacactgtg tgaaatttga tttcaagcca caaaagtggt
     1201 atatggttac catagtacac atctataacc gatggaagaa tagtgaactt cgatgttatg
     1261 tgaatggtga gctggcttcc tatggagaga taacatggtt tgtcaacact agcgatacct
     1321 ttgacaaatg tttcctgggc tcatcagaaa cagcagatgc taatagagta ttctgtggtc
     1381 agatgactgc agtttacctt ttcagtgaag ctctaaatgc agctcagata tttgctattt
     1441 atcagttggg cctgggatac aagggtacat ttaaattcaa agcagaaagc gaccttttcc
     1501 ttgctgagca tcacaaactt ttattgtacg atgggaaact ctctagtgcc attgcattca
     1561 cgtacaatcc acgggctaca gatgcccagc tttgtcttga atcatctcct aaggacaacc
     1621 cttcaatttt tgttcattca ccacatgcac tcatgctcca ggatgtaaag gcagttttaa
     1681 cacattccat ccaaagtgca atgcattcaa ttggaggagt acaagtacta tttccacttt
     1741 ttgcacagtt ggattacagg caatatttgt ctgatgagat tgatttgact atatgttcaa
     1801 ccttgctggc ctttatcatg gaattgttga agaactcaat tgctatgcag gaacagatgc
     1861 ttgcctgtaa gggcttcttg gtaataggat atagccttga aaagtcttcc aaatctcatg
     1921 ttagcagagc agtacttgaa ctttgccttg cattttcaaa atatctgagt aatctgcaga
     1981 atgggatgcc cctgctcaag caattgtgtg atcacgttct tcttaatcct gccatatgga
     2041 ttcatacccc agccaaggtt caactgatgc tctatactta tctgtccacg gaattcattg
     2101 gtacagtcaa catatataac accattcgga gagttggaac agtgcttctc atcatgcaca
     2161 cgctgaagta ctactactgg gcagtgaatc ctcaggatcg aagtggtatc accccaaaag
     2221 gattagatgg accgcgacct aatcaaaaag aaatgctttc tctacgagca ttcttgttga
     2281 tgttcattaa gcaattagtg atgaaggatt ctggagtaaa ggaagatgaa ttacaggcca
     2341 ttcttaatta cctactgact atgcatgagg atgacaatct aatggatgtc ctacagctgc
     2401 ttgttgcatt aatgtcagaa caccctaact ctatgattcc tgcttttgac caaaggaatg
     2461 ggttacgtgt tatctacaaa cttctggcat cgaaaagtga aggaatcagg gtacaagctc
     2521 ttaaggcaat gggttatttt ttaaaacatc tggccccaaa gaggaaagca gaagtcatgc
     2581 ttggacatgg attgttttca ttgctagctg aaaggctcat gcttcagaca aatttaatca
     2641 caatgaccac atataatgtg ctgtttgaga ttcttataga acagattggt actcaggtga
     2701 tacataaaca gcatccagat cctgattctt cagtgaagat acaaaaccct cagatactaa
     2761 aagtaattgc gaccctactt cgaaattctc cccagtgccc agagagcatg gaggttcgca
     2821 gagcctttct ttctgacatg attaaacttt ttaataacag tagagaaaac aggaggagct
     2881 tgctacaatg ctctgtgtgg caagaatgga tgctttctct ctgctatttt aatcctaaga
     2941 attcagatga gcaaaagata acagaaatgg tatacgccat attcagaatc ctgctttacc
     3001 atgcagtcaa atatgagtgg ggtggctggc gtgtatgggt agacacttta tcaatcactc
     3061 attcaaaggt cacttttgaa atacacaaag aaaaccttgc caatatattt agggaacagc
     3121 aaggaaaagt tgatgaagaa atagggctgt gttcttcaac ttcagttcaa gcagcctctg
     3181 gcattagaag ggatattaat gtttcagtag gatcccagca accagatacg aaggattctc
     3241 ctgtctgtcc tcatttcacc acaaatggta atgaaaattc aagtatagag aagacaagtt
     3301 cactagaatc tgcatctaat attgaactgc aaactactaa tacatcttat gaagaaatga
     3361 aagctgagca agaaaatcag gagttaccag atgaaggcac tttggaagaa acactgacaa
     3421 atgagacaag gaatgcagat gatttagaag tatcttctga cataatagaa gctgtggcta
     3481 tttcctctaa ttcttttata acaactggca aagattcaat gactgtcagt gaagtaactg
     3541 cttctataag ttctccttca gaagaggatg cctcagagat gccagaattc ttggataaat
     3601 ctatagtaga ggaagaggaa gatgatgatt atgtggaact gaaagtagaa ggcagtccta
     3661 ctgaggaagc taatctaccc acagagctcc aagataacag tttgtctcca gctgcatctg
     3721 aagccggtga aaaactggac atgtttggta atgatgacaa attaatattt caagaaggaa
     3781 aacctgttac tgaaaagcaa actgatactg aaactcaaga ttctaaagat tctggaattc
     3841 agactatgac agcatcaggg tcttcagcta tgtcaccaga aactactgtt tcccaaatag
     3901 ctgtagaatc agaccttggt cagatgctgg aggaagggaa gaaagcaact aacctcacta
     3961 gagaaaccaa attaattaat gattgtcatg gtagtgtctc tgaggcttct tctgagcaaa
     4021 agattgcgaa gttggatgtt tccaatgttg ctacagatac tgagaggctg gagttgaagg
     4081 ccagtcccaa cgtggaagca cctcaacctc atcgacatgt gcttgagata tcaaggcaac
     4141 atgagcagcc agggcaagga atagcaccag atgcagttaa tggacaaagg agggattcca
     4201 gatctactgt gtttcgtatt cctgagttca actggtctca gatgcatcaa cgtttgctca
     4261 ctgatctatt attttcaata gaaacagata tacagatgtg gagaagccat tcaacaaaga
     4321 cagttatgga cttcgtgaat agcagtgata atgtcatctt tgtacacaac acaattcatc
     4381 tcatctctca agtgatggac aatatggtca tggcttgtgg gggtatactg ccattgcttt
     4441 cagctgctac atcggctaca catgaactgg aaaatattga acctactcaa ggcctttcaa
     4501 tagaagcctc tgtgacattt ttgcagaggc taattagcct tgtggatgtg cttatatttg
     4561 caagttctct tggctttact gaaattgaag ctgaaaaaag tatgtcatct ggaggaattt
     4621 tgcggcagtg tctccgacta gtttgtgcag tcgcagtaag gaattgcttg gagtgtcaac
     4681 agcattcaca actgaaaact aggggagata aagccttgaa accaatgcat agccttattc
     4741 ctttagggaa atctgcagcg aagagcccag tggacattgt gactggcggt atatctccag
     4801 taagagatct tgacaggctt ctacaggaca tggatattaa tcggcttagg gcagttgttt
     4861 tcagagacat agaggatagc aaacaagctc aatttttagc cttggcagta gtatacttta
     4921 tctctgttct tatggtctcc aagtacagag acattttgga accccaaaat gaaaggcata
     4981 gccagtcatg tacagaaact ggcagtgaaa atgagaatgt atcactctct gaaatcacac
     5041 cagcagcatt cagcacttta actacggcat cagtggaaga atctgaaagc acatcatctg
     5101 ctcgaaggag ggactcaggc attggggaag aaacagccac tggtttagga agccatgtgg
     5161 aagtaactcc tcacacagca cctcctggtg tcagtgcagg cccagatgca atcagcgagg
     5221 tgctatctac tctttcttta gaagtcaata agtctccgga aaccaaaaat gatagaggaa
     5281 atgacttgga cactaaggct acaccgtcag tttcagtttc aaaaaacgtc aatgtgaaag
     5341 acattctccg aagcttggtt aacataccag cagatggagt cacagtggat cctgcccttc
     5401 tgccaccagc ctgccttgga gcccttggtg atctatctgt ggaacaaccc gtgcagttca
     5461 gatcttttga cagaagtgtc attgttgcag caaaaaagtc agcagtctca ccttccacct
     5521 ttaatacaag catacctacc aatgctgtca gtgtggtttc ctcagtagat tcagcccaag
     5581 cctcagatat gggaggagaa tcaccaggca gtagatcatc taatgcaaaa ttgccctcag
     5641 ttccaacagt tgattcagtt tcacaagatc cggtttcaaa tatgagtatt acagagaggc
     5701 ttgaacacgc tttggaaaag gcagctcctc tccttcgtga gatttttgtg gattttgcac
     5761 cttttctttc tcggacactt ttgggtagcc atggacaaga actgcttata gaaggaacaa
     5821 gtctggtttg catgaagtcg agtagttcag ttgtggaatt ggttatgcta ctgtgttctc
     5881 aggagtggca aaattctatt cagaagaatg caggccttgc ttttatcgaa cttgtcaatg
     5941 aaggaaggtt gcttagccag acaatgaagg atcatctagt aagagtagca aatgaagctg
     6001 aatttatcct gagcaggcag agagcagaag atattcacag acatgcggaa tttgagtcac
     6061 tgtgtgccca gtattctgca gacaaacgag aagatgagaa gatgtgtgat catttgataa
     6121 gagcagcaaa atatcgtgac cacgtgacag caactcaact aatccagaaa attatcaaca
     6181 ttctcacaga caagcatgga gcctggggaa attctgcagt gagtcgtcct cttgagttct
     6241 ggcgccttga ctactgggaa gatgacttgc ggcgccggcg acgatttgtg cgtaaccctc
     6301 taggatcgac acatcctgaa gcgacactaa aaacagccgt ggaacatgcc acagatgaag
     6361 atatccttgc taaaggaaaa cagtccatca ggagtcaggc tttaggaaat cagaactcag
     6421 aaaacgagat cctcctggaa ggcgatgatg atactctgtc atccgtggat gagaaagatt
     6481 tagagaatct tgccggtcct gttagcctga gcacaccagc tcagcttgtg gccccctctg
     6541 ttgtagtaaa gggcactctt tctgtcacct cctccgaact ctattttgag gtggatgaag
     6601 aggatcctaa cttcaaaaaa atcgacccca agatcttggc atatacagaa gggctgcatg
     6661 gaaaatggct gttcacagag atacgatcaa tcttttctcg tcgttatctt ttgcaaaata
     6721 cagccctgga gatctttatg gcaaacagag ttgctgtgat gttcaacttc ccagaccctg
     6781 caacagtaaa gaaagtggtt aactatctac ctcgtgttgg cgttggaaca agttttggat
     6841 tgcctcaaac cagacgtatt tcattagcta gtccacgtca gctttttaag gcttctaata
     6901 tgacccagcg atggcaacac agagagatat ctaattttga gtacttgatg tttctcaaca
     6961 cgatagcagg acggagttat aatgacttaa atcagtatcc agtgtttcct tgggtcatca
     7021 ctaattatga atcagaagaa ctggatctta ccttgcccac caacttcaga gatttgtcca
     7081 agccaatagg agctctgaac ccaaaaagag cagcattctt cgctgagcgt tatgaatcat
     7141 gggaagatga tcaagttcca aagtttcact atggtactca ttactcaact gcaagttttg
     7201 ttcttgcatg gctgctaaga atagaaccct ttacaactta tttcctaaat ttgcaaggag
     7261 gcaaatttga tcatgcagat cgaacttttt catcaatttc cagagcttgg cgaaacagtc
     7321 agcgtgatac ctctgatatt aaggagttga tccctgaatt ttattatctc cctgagatgt
     7381 ttgtcaactt caataattat aatcttggag tgatggatga tgggacagta gtgtctgatg
     7441 tcgaacttcc tccttgggcc aaaacctcag aagaatttgt tcacataaac agattggccc
     7501 tggagagtga atttgtttcc tgccagcttc accaatggat tgatctcatt tttggctata
     7561 aacagcaagg accagaagct gtccgagccc tcaatgtgtt ctattacttg acctatgaag
     7621 gagctgtcaa tctgaattca ataactgatc ctgtgttgag agaggctgtt gaagctcaaa
     7681 tccgaagttt tggacagact ccttctcaac tactcataga gccccatcct cccagaggtt
     7741 ctgccatgca agtgagtcca ttgatgttca cagacaaagc ccagcaggat gttatcatgg
     7801 tcctcaagtt tccctccaac tcccctgtta ctcacgtggc agccaacacc cagcctggtt
     7861 tggcaactcc cgctgtgatc acagtcactg ctaacaggtt atttgcggtg aacaaatggc
     7921 acaaccttcc tgctcatcaa ggtgctgtac aagaccagcc ataccagctg ccagtggaaa
     7981 tcgatcctct catagccagc aatacaggaa tgcacaggag gcaaatcact gaccttttag
     8041 accaaagtat tcaagtgcat tcccagtgct ttgtcatcac ttcagacaac cgctatattc
     8101 tcgtctgtgg cttctgggat aaaagtttca gagtctattc tacagacaca ggaagattga
     8161 tccaagtggt gtttggccat tgggatgtcg tcacttgcct tgctcgttct gagtcatata
     8221 ttgggggaaa ttgctacatt ctctcagggt cacgtgatgc aactcttttg ctgtggtatt
     8281 ggaatggaaa atgcagtggg attggagata acccaggcag tgagactgct gctcctcggg
     8341 ccattttgac cggccatgac tatgaggtca catgtgctgc ggtgtgtgcg gagctaggcc
     8401 tggtgttgag tggttcacaa gaaggaccat gtctcataca ttccatgaat ggagacttgt
     8461 tgaggacctt ggagggtcct gaaaactgcc tgaaaccaaa actcattcag gcttcaagag
     8521 agggtcattg tgtcatattc tatgaaaacg gcctcttctg tacattcagt gtgaatggaa
     8581 aactccaggc cacgatggaa acagatgata acataagagc catccagctg agccgagatg
     8641 ggcagtacct gctcacagga ggagacagag gagtggtcgt ggtccggcag gtgtcggacc
     8701 tcaagcagct ctttgcctat ccaggatgtg acgctggaat ccgggccatg gcgctgtctt
     8761 acgaccagag gtgcatcatt tctggcatgg cttcaggaag cattgtgcta ttttacaacg
     8821 actttaaccg gtggcatcat gaataccaaa cccgctactg atggtgacag ctgtacatca
     8881 actctgcccc taggatgagc agaagtacct ggagcatcat tctcttctac cacatctgaa
     8941 tgtaacttaa atttgctcaa agaagcaaaa tattttttaa agttattaat aattgctatt
     9001 tttgtagtct ttgcttgact tttttggggg ggattagcaa agcagaaaac tggctgctgg
     9061 gttctgtagt tttaaaaaat ctatattttt agtcataatg agaagtctat tttcaccaat
     9121 tatggaaaca tacagtggag caagtaaacc acttattcca gctataatat tatgaagaac
     9181 atttcccatg catctacaag cttgagaaat aggattttca cagtggggaa gtgggttaca
     9241 atattggaat aggaaaattt gatgctgtaa tttgggtcct gtatttttcc aaacaactgt
     9301 gcttcttcag cactaatatt tctgggattt aaatagtaat gtttaaatta tggtaaatgt
     9361 aatttaaaac atctcaatta agtctgtcta tcaatattgt tcttcaagca tgttttagac
     9421 ctagaaaagt atggtttggg ggaggctatt ttattgtgtg gttagcacaa ggaatctaat
     9481 ttatagcaag tgtgaaatag ttaccatttt ttcctgatct gtcatcttca tagcacaaca
     9541 aaacgaaatg atggaaatgc tcttgagctc acaacatttg tttttctttt aaagtaaatg
     9601 caagtaccaa agctcactac tgcggtttgc ctgtgcctgg acaatgaggc ggagccactg
     9661 ttgttttgtt ggggcacccc cttccctccc cgggtttgca aatagaggct accgggtgct
     9721 gtattcagca acacctgttt tactatttgt tattaaacta tcatctccac cttccttttg
     9781 attagcaatt tgtactaaga aacgaaacaa tgttatttgg tggtgtataa ttctactttt
     9841 ctagtagatt actgtgtgga attctgtgaa aaatatttga gaaaaggcct gtattgcata
     9901 aataaattct ttgtatgttg tgaactttga tctctatttc tcttgcaaca gacttcaagt
     9961 ggtccctctt tttttcctac acactcagct cttctctaaa agcaaggatt tggaatgaac
    10021 aattcagttt gacagaaaaa gctgaataaa atggcatctg taattgaatt gttggaaatg
    10081 ccttttttgc tcctaaattt taaacatcat taataaaata atgattcaca aagaaagaaa
    10141 atgtcaaa
//
