LOCUS       NM_014873               7773 bp    mRNA    linear   PRI 11-JAN-2025
DEFINITION  Homo sapiens lysophosphatidylglycerol acyltransferase 1 (LPGAT1),
            transcript variant 2, mRNA.
ACCESSION   NM_014873 XM_375837
VERSION     NM_014873.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7773)
  AUTHORS   Sun,H., Zhang,J., Ye,Q., Jiang,T., Liu,X., Zhang,X., Zeng,F.,
            Li,J., Zheng,Y., Han,X., Su,C. and Shi,Y.
  TITLE     LPGAT1 controls MEGDEL syndrome by coupling phosphatidylglycerol
            remodeling with mitochondrial transport
  JOURNAL   Cell Rep 42 (11), 113214 (2023)
   PUBMED   37917582
REFERENCE   2  (bases 1 to 7773)
  AUTHORS   Gong,H., Ma,C., Li,X., Zhang,X., Zhang,L., Chen,P., Wang,W., Hu,Y.,
            Huang,T., Wu,N. and Wang,X.
  TITLE     Upregulation of LPGAT1 Enhances Lung Adenocarcinoma Proliferation
  JOURNAL   Front Biosci (Landmark Ed) 28 (5), 89 (2023)
   PUBMED   37258473
  REMARK    GeneRIF: Upregulation of LPGAT1 Enhances Lung Adenocarcinoma
            Proliferation.
REFERENCE   3  (bases 1 to 7773)
  AUTHORS   Kawana,H., Ozawa,M., Shibata,T., Onishi,H., Sato,Y., Kano,K.,
            Shindou,H., Shimizu,T., Kono,N. and Aoki,J.
  TITLE     Identification and characterization of LPLAT7 as an sn-1-specific
            lysophospholipid acyltransferase
  JOURNAL   J Lipid Res 63 (10), 100271 (2022)
   PUBMED   36049524
REFERENCE   4  (bases 1 to 7773)
  AUTHORS   Soh,J., Iqbal,J., Queiroz,J., Fernandez-Hernando,C. and
            Hussain,M.M.
  TITLE     MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by
            decreasing lipid synthesis and lipoprotein secretion
  JOURNAL   Nat Med 19 (7), 892-900 (2013)
   PUBMED   23749231
REFERENCE   5  (bases 1 to 7773)
  AUTHORS   Wu,J.H., Lemaitre,R.N., Manichaikul,A., Guan,W., Tanaka,T., Foy,M.,
            Kabagambe,E.K., Djousse,L., Siscovick,D., Fretts,A.M., Johnson,C.,
            King,I.B., Psaty,B.M., McKnight,B., Rich,S.S., Chen,Y.D.,
            Nettleton,J.A., Tang,W., Bandinelli,S., Jacobs,D.R. Jr.,
            Browning,B.L., Laurie,C.C., Gu,X., Tsai,M.Y., Steffen,L.M.,
            Ferrucci,L., Fornage,M. and Mozaffarian,D.
  TITLE     Genome-wide association study identifies novel loci associated with
            concentrations of four plasma phospholipid fatty acids in the de
            novo lipogenesis pathway: results from the Cohorts for Heart and
            Aging Research in Genomic Epidemiology (CHARGE) consortium
  JOURNAL   Circ Cardiovasc Genet 6 (2), 171-183 (2013)
   PUBMED   23362303
REFERENCE   6  (bases 1 to 7773)
  AUTHORS   Traurig,M.T., Orczewska,J.I., Ortiz,D.J., Bian,L.,
            Marinelarena,A.M., Kobes,S., Malhotra,A., Hanson,R.L., Mason,C.C.,
            Knowler,W.C., Bogardus,C. and Baier,L.J.
  TITLE     Evidence for a role of LPGAT1 in influencing BMI and percent body
            fat in Native Americans
  JOURNAL   Obesity (Silver Spring) 21 (1), 193-202 (2013)
   PUBMED   23505186
  REMARK    GeneRIF: LPGAT1 is a novel gene that influences BMI in Native
            Americans.
REFERENCE   7  (bases 1 to 7773)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   8  (bases 1 to 7773)
  AUTHORS   Yang,Y., Cao,J. and Shi,Y.
  TITLE     Identification and characterization of a gene encoding human
            LPGAT1, an endoplasmic reticulum-associated
            lysophosphatidylglycerol acyltransferase
  JOURNAL   J Biol Chem 279 (53), 55866-55874 (2004)
   PUBMED   15485873
  REMARK    GeneRIF: human LPGAT1 is an endoplasmic reticulum-associated
            lysophosphatidylglycerol acyltransferase
REFERENCE   9  (bases 1 to 7773)
  AUTHORS   Hoja,M.R., Wahlestedt,C. and Hoog,C.
  TITLE     A visual intracellular classification strategy for uncharacterized
            human proteins
  JOURNAL   Exp Cell Res 259 (1), 239-246 (2000)
   PUBMED   10942595
REFERENCE   10 (bases 1 to 7773)
  AUTHORS   Gueguen,M., Patard,J.J., Gaugler,B., Brasseur,F., Renauld,J.C., Van
            Cangh,P.J., Boon,T. and Van den Eynde,B.J.
  TITLE     An antigen recognized by autologous CTLs on a human bladder
            carcinoma
  JOURNAL   J Immunol 160 (12), 6188-6194 (1998)
   PUBMED   9637538
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            D86960.1, AC096637.1 and AI264005.1.
            
            On Nov 22, 2018 this sequence version replaced NM_014873.2.
            
            Summary: This gene encodes a member of the lysophospholipid
            acyltransferase family. The encoded protein catalyzes the
            reacylation of lysophosphatidylglycerol to phosphatidylglycerol, a
            membrane phospholipid that is an important precursor for the
            synthesis of cardiolipin. Alternative splicing results in multiple
            transcript variants. [provided by RefSeq, Mar 2016].
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.142244.1,
                                           SRR1660807.120112.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000366997.9/ ENSP00000355964.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1968              D86960.1           10-1977
            1969-7676           AC096637.1         78432-84139
            7677-7773           AI264005.1         21-117              c
FEATURES             Location/Qualifiers
     source          1..7773
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q32.3"
     gene            1..7773
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /note="lysophosphatidylglycerol acyltransferase 1"
                     /db_xref="GeneID:9926"
                     /db_xref="HGNC:HGNC:28985"
                     /db_xref="MIM:610473"
     exon            1..191
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /inference="alignment:Splign:2.1.0"
     exon            192..456
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /inference="alignment:Splign:2.1.0"
     CDS             219..1331
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /EC_number="2.3.1.22"
                     /EC_number="2.3.1.62"
                     /note="isoform 1 is encoded by transcript variant 2;
                     family with sequence similarity 34, member A;
                     acyl-CoA:lysophosphatidylglycerol acyltransferase 1;
                     acyl-CoA:monoacylglycerol acyltransferase LPGAT1;
                     lysophospholipid acyltransferase 7;
                     stearoyl-CoA:1-lyso-2-acyl-PE acyltransferase;
                     2-acylglycerophosphocholine O-acyltransferase"
                     /codon_start=1
                     /product="acyl-CoA:lysophosphatidylglycerol
                     acyltransferase 1 isoform 1"
                     /protein_id="NP_055688.1"
                     /db_xref="CCDS:CCDS31018.1"
                     /db_xref="GeneID:9926"
                     /db_xref="HGNC:HGNC:28985"
                     /db_xref="MIM:610473"
                     /translation="MAITLEEAPWLGWLLVKALMRFAFMVVNNLVAIPSYICYVIILQ
                     PLRVLDSKRFWYIEGIMYKWLLGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQ
                     ATGDVCTLMMCLQDKGLVVAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQL
                     LLLKKHLENNYRSRDRKWIVLFPEGGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGAT
                     KIILNALVAQQKNGSPAGGDAKELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRK
                     PTVTHVHYRIFPIKDVPLETDDLTTWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVS
                     REMTLSNLWIFLIQSFAFLSGYMWYNIIQYFYHCLF"
     exon            457..575
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /inference="alignment:Splign:2.1.0"
     exon            576..671
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /inference="alignment:Splign:2.1.0"
     exon            672..945
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1072
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..1179
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..7773
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3417..3422
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /note="hexamer: AATGAA"
     polyA_site      3433
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /note="major polyA site"
     regulatory      6225..6230
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /note="hexamer: AATAAA"
     polyA_site      6250
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /note="major polyA site"
     regulatory      7752..7757
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /note="hexamer: AATAAA"
     polyA_site      7773
                     /gene="LPGAT1"
                     /gene_synonym="FAM34A; FAM34A1; LPLAT7; NET8"
                     /note="major polyA site"
ORIGIN      
        1 agtccgggcg aacgcggccg ggcccttggg gaccgagtct cggcgccgcc ggggaacggg
       61 cgcgggccgc gccacagccg gagcggggca gggccccgcc accgccttct tccgccggcc
      121 ccgccgccgg ccatgcattc ttccggctcc tctgactccc aaagccccgg ctggggcccg
      181 gccagcccga gaaagacagg acggagtcca gtgtgagaat ggctataact ttggaagaag
      241 ctccgtggct gggctggctc ttggtgaaag cactgatgag gtttgccttc atggtcgtca
      301 acaacctggt tgctattcca tcctacatct gctatgtaat tatacttcag ccccttcgag
      361 tgctggacag taagcggttc tggtatatcg aaggaatcat gtataaatgg cttttaggaa
      421 tggtagcttc ctggggatgg tatgctggat atacagtgat ggaatgggga gaagatatta
      481 aagcagtttc aaaagatgaa gcagtgatgt tggtgaatca tcaggcaaca ggagatgtgt
      541 gcacactgat gatgtgcctc caggacaaag gactggttgt tgctcagatg atgtggttga
      601 tggatcatat ttttaagtac acaaactttg gaattgtttc tctagttcat ggagacttct
      661 ttataagaca gggaagatct tatcgtgacc aacagctgct gcttctcaag aagcacttag
      721 aaaataatta caggagcaga gatcgaaaat ggattgtttt gtttccagaa gggggcttcc
      781 tcaggaagag gcgagaaaca agtcaggcat ttgccaagaa aaataacttg ccatttctta
      841 caaatgttac tctgccaagg tctggggcaa caaaaattat tttgaatgca cttgtagcac
      901 aacagaaaaa tggaagtcca gcaggaggag atgctaaaga attagacagc aaatcaaaag
      961 gcctccagtg gataatagat acaacgatag cttatcccaa agctgaacct atagatattc
     1021 aaacctggat ccttggatac aggaaaccaa cagtcacaca tgtacattac aggatctttc
     1081 caattaaaga tgtacccctg gagactgatg accttaccac ttggctctat cagcggtttg
     1141 ttgaaaaaga agacctctta tcacattttt atgaaacagg agcttttcca ccttccaagg
     1201 gccataagga agctgtttcc agggagatga ccctcagcaa cttgtggata tttctcatac
     1261 agtcttttgc atttttgtca ggctatatgt ggtacaacat cattcagtat ttttaccatt
     1321 gcctgtttta ggaattgacg tggacttgtc aaggtcaccg taggagttca gactttcttt
     1381 cataagtgtg cattatttta catgtgcaaa tcagaatata tttaaaaaaa agcaaaagaa
     1441 attcaatgga tggattaata tttatccccc tttgggatat tttaaaatct actaaaatga
     1501 ggattagtaa tataatgacc tgctaatata ttttaagaac atgttttaaa aagatacact
     1561 ctatcacata tttaagcaaa catcacattt ggagaagagg aaatcataaa atcatcctag
     1621 aagactatct gagagaaatt ctgttgccac cagttatact tgacaattta gttgaagctc
     1681 agaaagttat attcatccct cttagctgta gtctatatta gggcagttct ctagaacgcc
     1741 cacatttcca ccaactcagt aaacttgagg ggagctggtt ggcacctcgt gaagaactct
     1801 ttccctgtcg tttgcagtaa caaactccag tctgttgcag taacaaactc cagtctgttg
     1861 cagtaacaaa ctctagaata ttgacattct ctgtggggga aaagcagtgt ccactggacc
     1921 ccttctggta ctggatgtgt tctttacaaa ggctagctca gtccaacact gtgtttacat
     1981 acactcgtgc ttttccttat ctgacttctc attttgtatc agaggcatat cataaattga
     2041 taattttgca aaatgcactt ttttgagatg cagatatagc aaaggattag taatatagcc
     2101 tgaaaacaaa tgggagcata gcagtgtgtg aggttctcga gaactgtctt gtctctgtgt
     2161 gtttatttgc ctgccagtgc tctccagcgc catcctgccc tggacaccac cctgacgtga
     2221 tgcctctatt gcagctcaga ggctttattt tttccatttt gacattggca ctaaatgcat
     2281 ttggggatgg ttaaaacaaa ttactataga acatttaaat gatcagttta aggggaaata
     2341 ggctagttta tagaaaaata agagctagtg gcttataatg gtgacaggtt ctcatgtggc
     2401 acccctagga cctgtgcaga cagtagtctg ttgaatcatt acatcaagga gctgcccctg
     2461 tcagggtgag tgtaattagg aacgatacca gcacataagg ctccccccaa tctcttccag
     2521 ttgctttttc ttttttcttt tttttttaga caggtcttac tctgtcaccc aggctgtagt
     2581 gcagtggcat aatctcagct cactgcagtc tctgcctccc gggttcgagc gattctcctg
     2641 cctcagcctc ccgagtagct gggactacag gcacccacca tcatgcttgg ctaatttttg
     2701 tatttttagt agagatgggg tttcaccatg ttggccaggc tggcctcgaa ctcctgacct
     2761 caggtgatct gcccacctcg gcttcctaaa gtgctgggat tgcaggcgtg agccaccacg
     2821 cccggcctcc agttgctttt gaagagggta aagtcaagtt tctatttcta gaaaacattt
     2881 tttagaaatt tgttgcgatg tttgtacaat ttacctcata agagaaccac acccttctcc
     2941 aaaagtgctg gtactgcatc agtgagatga gtagggtttt tgtttgggat tgtaagacta
     3001 ttaagatcct agtaagtcag tggtagttta ctgtgatgtg agcattgtag attcccccgt
     3061 tgtcactaat cacacaacaa ttttgagaag taggctataa aacaaaaaaa ggttgctgtt
     3121 ttctattttt aaataaacca aaaaaaaaca gaaaagatgt gaattttccc cagttatgtg
     3181 ggaaaggtaa agcaacacca aataaaagcc cacagcagct tcatctttac gataactcag
     3241 tgcatatgtg aaagagaatg atgcattaac tgaaatacct cattgaatat tatactacta
     3301 ctggtaaaat gcagaagaca gtgttaatgt gtttggtttg gggactggtt gttataaaat
     3361 gcaatttttt tttaaatcta agcatttcat tatgtgttct acagtgtcgg tgaataaatg
     3421 aaaccaatct caatttagag gtatggatga tgacagaaag cccaatagaa gcttaatgat
     3481 gcttctgttt gaggcccagc aagcaccact aaattactgg atgaaatgaa attgttcact
     3541 tgagggatta gtcaaccatc tgggggagaa gttgctcact gtcaaataca gcatgcacgg
     3601 tcctagctga tagacctttt cctcattgct acagcaagcc acagggtaga gtgaccagtt
     3661 ctcctatcca aaaataaatg cgaacatgca tacataaatg tggctgaggg ccacttttgc
     3721 catcactgtg ctccaaagga acatgatatt gttaaatata ctgtacacat taaactattc
     3781 tataagatgc tttacttttc aagtacggtg tcattttcac agtctccagg gtgacaaatg
     3841 ccaatagata tgtgagttaa tttttttaaa tatctccgtg agttgtaaat agatgtgtat
     3901 ttgatctgcc ctatccttct ttgattcttt aacatgttct ctctcttctg tttgcaaaat
     3961 atgtttgaaa gcattggtag tgctttcctt atcagtaact ggagttctcc tgcttgcact
     4021 agagaaggta aagagagaat cagtattctt atatggcaat ctggggaagc agcaatatgc
     4081 cactgtacaa aactgaagaa aagttcctaa tttgtacttt gtgaagggag atgaaaggac
     4141 gtttaaagta tatatatttt gtcaagagga aagaagataa aactatgcca gttttatatc
     4201 aatagcttgt agaagctcag ctcttcttgg tcttggctag actgcctaga ttcccacagc
     4261 agacaaggtt gagaatccat tgctggaatc ttggtattga tgagttacag tgatggaaca
     4321 tgtgcttggc cacaggcagg tccagtcact gcaaaagtga ccaagccagc aggtcaccct
     4381 taacttcaga aacaattatt ggtggtgaac tgtacttaaa ttgcagagaa acctgtaagt
     4441 aatggaaggt aaagaaaaat tacagaatgg aaaataatat tttgggcaag caaacaaatt
     4501 cactgagaat tccaaaagta tattaaaaaa gaagatagct atgagttcag atctatctta
     4561 ttggtcttta atattacaac caatccttaa ctttccacta taaaggaagg attactagat
     4621 tgattacttt ctggatagat aatctggtaa taaatgatag gtaaatcaaa aattactttt
     4681 atttaggagt ttgaattctt actctcatca gacatttttt ttctagggac gcttactaat
     4741 taaatgattt aagttgtttc ttaggggttt tttgcctata tatttatgac tgtgttaatg
     4801 agtagtgaaa tgatgcggaa agacagctat caggaagagg aaatacagaa gcctgaataa
     4861 tctatgggtt agaaaagcat ccctgaataa tcaaaaattg gcagtattgg cattgttctc
     4921 aagccttttt atgaaaatga aatctgaaat caccaaatgt aaacctggga acattattct
     4981 agtgttgctg tcttggattc atgttaagaa gcgtcttcat tctttgctca tgttgcccac
     5041 ttcttgtgga tttgtctgag tgttttttga caatcacttc cttaaagact cttctgaact
     5101 agttggacct ggttaatcat agagagtagc ctttaatcat ggatagtctt cttggattat
     5161 ttttatattt gaaaagaaaa tgttttattt gcactactga gtaggaagag ttaattgttt
     5221 tctttgttct ttttttgaag tcattacaca ggacttcact ccagagttac cattatgagt
     5281 gtgttcagct ctggtccaca gaggatggat aaaaatggtt tgttatgttt ttttgctctg
     5341 cagtgctatg agccttatat ctgttaatat gaaggacaaa gtcaaaagca gcagtggata
     5401 gcaggaaggg tagagactaa tatgtttggg accaaaacca tctaagttag agatttccag
     5461 atcacagagg ggctgggcat tctctggagc agtcattggt tggtgcttta ttgtaatcat
     5521 tttgcgccaa tccccaacaa ttaggaactg gaccctggga ataagctgag ggtgctgaac
     5581 tgttggggaa gggtgactgt agccacatgg aagataaaat atgggttttt ctgcaaaatt
     5641 tccatctgag ggtttttaca tttaatattt ttttaagaca gtttaaagag caaacgtttt
     5701 ttaagtgtat tctagttgca aagtatgcac acatatcttg aatggcttta tttttattgt
     5761 gtaaaactgt tgaacacatg actgtgatgc acaaattctt tacgtgtaag gagtctatgc
     5821 attttacagt aacttatttt atgatcgggt gatgagacag ttatactttc aactgccatt
     5881 atttttatta agtgctttca ttttctttac agttattata aaattgtatt tattttatac
     5941 agatgggttt tcattttcct gatgctgtaa tgtttacttc agcttgttga cctttctttg
     6001 tgttatctgc atgttgtaac gtgtgataag aatgaatgta aaggctgtgg caactgtaat
     6061 taatttttgt aaagggctgg tcacacgtgg atctggttta tgaatgcatt tgggatgatt
     6121 ttggtaacca gatcaccttt tcagaaattt agatgtgaac accaaaagaa gcattttctc
     6181 aacaaaaatt aatagctggt tctatttttt ttaaacctag aaaaaataaa gttgattttt
     6241 ttcaattaaa gtgcttttaa ttcttagcag tggggatggg gcatgtgtgt tttaccagag
     6301 ctatttgggc attaatatct gcaggcaagt acttaaagca cactgtggca gttggatgct
     6361 gaaggcaaac tgaaaaacca aatgaaaaaa catcagactt ccttctttgg tttaaaaata
     6421 tttccccctt tctccccatt ctcccaatcc agtggtgtgc tggtaaatgt ttagcagttc
     6481 actcttctgg gagaaaatta tgtattcaac tatacatgtt tgttataaat tttgctgata
     6541 gcaagaacat ataacacaat taacaaataa taagatacaa atactttatt gtaaatccca
     6601 tatagccagt tgattctcac agtatactta gttgctcagg aaagaactaa aatgcttttt
     6661 taaaaggata cttaattgct ttttgctcaa ctcctacagt caacctatga ttgattgtct
     6721 ttcaactgtg atttgaaaaa tggcagactg tccaaatcta actcatttcc caataaattt
     6781 attatcattc aatctgatac gtgatctact gttaaaactg tttcttacca tggtacatat
     6841 tagactcatt aagccgaaac cacttttagc tttaacatta attgtaaatt tatatgattc
     6901 aattttcata accaatgctt aacaactgca ggcaaaattc taaaatgtga ccactgggtc
     6961 ttgggaatca gtaggggctg tatccagcac accactgccc catccttttt ttcttaacta
     7021 ttagtgttga ataaacttct catagttaat ctacttgctg aactcaggaa attcctatca
     7081 ctgaccctgg ccagggcttt aaagggtagg aaaagcatta atgtcagtcc tacacagcga
     7141 acttttgatt tagaagaatg tgacagaaag aaaacattta ctgaaataca tgggaagctt
     7201 gcatatttct aaagttgtct ttatactttt catttctcaa agctaagtaa actgtggtat
     7261 aggcatctct aagatgttag catttaaaac atcaattgtt ttattgatgt ttaaacaatt
     7321 gtttaaatcc cactgaaaaa tttaaatatt aaaatatctt gcacagtcta ccaaatgagt
     7381 taaatcgtta cagtcgtgtc tacctcttat ttttctatct gtatttaggc tgctgttttg
     7441 gtgagattct aatttctttt tcccctggaa ctactttctg tggaagacaa ggaacagact
     7501 ggggacagag gcctgaaaac aaattggaag cactcagaga tctattgctg accagcccta
     7561 ttcctcatga gttggcgggg ggaaagccat tgtttttaat ttccacttaa tatgaaaatg
     7621 cttgttttta aaatgttttt tcctgctgaa caaatgtatt tttaaaagga aaaaaattct
     7681 cttttggctc taagaagtca gctgtatgag caggcgtgac catatcataa catgctgata
     7741 tgatagaaat caataaattt ttacctctca gga
//
