LOCUS       NM_001395976            3445 bp    mRNA    linear   PRI 29-OCT-2022
DEFINITION  Homo sapiens zinc finger domain-containing protein LOC728743
            (LOC728743), transcript variant 3, mRNA.
ACCESSION   NM_001395976
VERSION     NM_001395976.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K,
            Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R, Zhang
            J, Hudek AK, Li M, Haddad M, Duggan GE, Fernandez BA, Kanematsu E,
            Gentles S, Christopoulos CC, Choufani S, Kwasnicka D, Zheng XH, Lai
            Z, Nusskern D, Zhang Q, Gu Z, Lu F, Zeesman S, Nowaczyk MJ, Teshima
            I, Chitayat D, Shuman C, Weksberg R, Zackai EH, Grebe TA, Cox SR,
            Kirkpatrick SJ, Rahman N, Friedman JM, Heng HH, Pelicci PG, Lo-Coco
            F, Belloni E, Shaffer LG, Pober B, Morton CC, Gusella JF, Bruns GA,
            Korf BR, Quade BJ, Ligon AH, Ferguson H, Higgins AW, Leach NT,
            Herrick SR, Lemyre E, Farra CG, Kim HG, Summers AM, Gripp KW,
            Roberts W, Szatmari P, Winsor EJ, Grzeschik KH, Teebi A, Minassian
            BA, Kere J, Armengol L, Pujana MA, Estivill X, Wilson MD, Koop BF,
            Tosi S, Moore GE, Boright AP, Zlotorynski E, Kerem B, Kroisel PM,
            Petek E, Oscier DG, Mould SJ, Dohner H, Dohner K, Rommens JM,
            Vincent JB, Venter JC, Li PW, Mural RJ, Adams MD and Tsui LC.
  TITLE     Human chromosome 7: DNA sequence and biology
  JOURNAL   Science 300 (5620), 767-772 (2003)
   PUBMED   12690205
REFERENCE   2  (bases 1 to 3445)
  AUTHORS   Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
            Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
            B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
            Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
            GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
            Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
            Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
            SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
            Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
            Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
            Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
            Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
            Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
            Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
            Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC073111.8.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9304717.735593.1,
                                           SRR9304715.432023.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000642087.2/ ENSP00000493097.1
            NMD candidate          :: translation inferred
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-229               AC073111.8         25751-25979
            230-1134            AC073111.8         27659-28563
            1135-3445           AC073111.8         30235-32545
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q36.1"
     gene            1..3445
                     /gene="LOC728743"
                     /note="zinc finger domain-containing protein LOC728743"
                     /db_xref="GeneID:728743"
     exon            1..229
                     /gene="LOC728743"
                     /inference="alignment:Splign:2.1.0"
     exon            230..1134
                     /gene="LOC728743"
                     /inference="alignment:Splign:2.1.0"
     CDS             258..869
                     /gene="LOC728743"
                     /note="isoform 1 is encoded by transcript variant 3"
                     /codon_start=1
                     /product="zinc finger protein LOC728743 isoform 1"
                     /protein_id="NP_001382905.1"
                     /db_xref="CCDS:CCDS94231.1"
                     /db_xref="GeneID:728743"
                     /translation="MTELASSGGGSPAGDGEEGLGDERGLVIHHPAEEQPYRCPLCGQ
                     TFSQQPSLVRHQKAHAGAGRAAAFVCPECGKAFSVKHNLEVHQRTHTGERPFPCPECG
                     RCFSLKQNLLTHQRIHSGEKPHQCAQCGRCFREPRFLLNHQRTHARMPAPHPRRPGVF
                     GERRPYFCPRCGKSFAREGSLKTHQRSHGHGPEGQAAHLGRVL"
     exon            1135..3445
                     /gene="LOC728743"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1915..1920
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LOC728743"
                     /note="hexamer: AATAAA"
     polyA_site      1932
                     /gene="LOC728743"
                     /note="major polyA site"
     regulatory      3424..3429
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LOC728743"
                     /note="hexamer: AATAAA"
     polyA_site      3445
                     /gene="LOC728743"
                     /note="major polyA site"
ORIGIN      
        1 agaagttggc aaggttgtgt gtaaggtcgg gtggggtggg gtcagctctc ccgattaatg
       61 cagctatttg ataagagcaa cgtcgcggga cgcttgccgt ctttatgggg gcggggagaa
      121 ggggcgcggg tgtcgctgcg ggagagttac cgtatttgcg ttgagcagcg cagactgtag
      181 agcaaagagc tgcggccgga gaccggagga gcaggggctc agctgggctg gactggtgat
      241 tgcagctgga agtgcccatg accgagctgg cgtcctccgg gggcgggtcc cctgcggggg
      301 acggggagga gggtctgggg gacgagcgag gcctggtcat ccaccaccct gcagaggagc
      361 agccctaccg ctgcccgctg tgcggccaga ccttctcgca gcagcccagc ctggtgcggc
      421 accagaaggc gcacgccgga gcgggccgcg cggctgcctt cgtgtgtccc gagtgcggca
      481 aggccttcag cgtcaagcac aacctcgagg tgcaccagcg cacgcacacc ggggagcggc
      541 ccttcccctg ccccgagtgc ggccgctgct tcagcctcaa gcagaacctg ctcacgcacc
      601 agcgcatcca cagcggcgag aagccgcacc agtgcgcgca gtgcggccgc tgcttccgcg
      661 agccgcgctt cctgctcaac caccagcgca cccacgcgcg catgcccgcg ccgcacccgc
      721 gccgccccgg cgtcttcggg gagcggcggc cctacttctg cccccgctgc ggcaagagct
      781 tcgcgcgcga gggctcgctc aagacccatc agcgcagcca cggccacggg cccgagggcc
      841 aggcggccca cttaggacgc gtgctatgat gcgcccgggg cctgctgccg acggctgctt
      901 cccgccccgc acgtgcgtcc ccgacccctg gagatggccc tgggccgcag ctccctctct
      961 agatgggatc ccgggagagg ggcagcgctg gcttgggctc ttgaaggtgt gggccgccgc
     1021 caggctccgg ccgcccgctc gcgttcctcc ctcgggaccc tctggctggc tgcgcacagc
     1081 tgcttccggc tcctgccatg gttctccttc tctggcccat ccggcctaga gcagttgcag
     1141 agtgggcagg atcttaagac ccgataggtg cagaacccat ctggacacgg agaccaggaa
     1201 tggagttcca tggaggcctg gctggcactg cacccgggca tgaggacaca tccagtaaga
     1261 agacctgcct caagaggtgc actgcggtga ccagtggagg tgactggttg gagcctggaa
     1321 ttggaagcag attccaagct ctggtggaca aactctccag gcctggtggg aatcacagct
     1381 ggggcagacc tcatcctggc tgcctggcca caggccccca ctctctgcca ctggtggtag
     1441 gacgatgcct gtgtggagag ctggcttctc tgctcccgcc tggtccacca cttggctaga
     1501 gttcagagac aggaagtgat tggtctaagc taacacagca agttggtggc agacctggtt
     1561 ctagaggcaa aaccttcttc cagatgtgaa tgaaacctgc aggcttcatt ttcctttctg
     1621 agcagtgctt cttagctctt tggagacacg aagcccttgg aaaatctgat gaaggttacg
     1681 gaccttccct aggaaaacag ataactgacg tagactcaaa aaccccaagc aatttcagga
     1741 gccactggac tccctgaatg aaacccatcc ctggactcca ggctaagaac ctcagccctg
     1801 gggacttcac ctgctgccct ttccttacct gtcacacatt gagccccgag tcaaggccac
     1861 tgtacaagta gtgcccctcc ctccccctgg ccaagcctcc ttcccttgtt caggaataaa
     1921 gaattccgag gagccctttt tagtcattcc cttctcccag acctaacgaa tggtgcgtca
     1981 ggtttctgga gcctcatttc ccttccccag acattggcag aggtcccttg ggctagattt
     2041 tctcttctgg ttttgtttct tgttctgcct gactggccgc tggcttccac aaaggagccc
     2101 tttgctcctg gcctgggctc tgatttcact gtgtggtctc aggggaagct ggactgctgt
     2161 ggacgctggt gggagcttga gtctggtctg agtctgcccc agggagaaag aatcctgctt
     2221 ccaccaacca agcccagtca gcggttcctc ccagctggcc aagtgttcag cccagtgggc
     2281 tggggaggaa gaggatgagg gcctcgctcc tggtgcctgt ggctctgggc agggtgagag
     2341 gtcggtggag gatctttctg tgtgttctct gagtatgcag cagtgcagtt gaagggaaca
     2401 gggcccaggc aggcagcagg gcaaggactc ctcccatctt cacacctgaa ccagtcagcc
     2461 tggaagctac aagttctcac ctgcctcccc agaatgaaca tcagaaaagg caaaactgac
     2521 cagggctggg atgggtttgg gtcagcgtgg ttggagggca gcctgtggat ccctgcactg
     2581 gagtcttgct gtcttcgatg caggttggat catacattgt tacctcctac tgtatgcctc
     2641 accctggaat agcagaatgc tcagggggag atccgagaac gagaaggtgc tcccagcccc
     2701 aggagcttcc agtctggctc tgatccttgg ccgacctaga ggaaacctcc acacacgccc
     2761 cttttgtgct aatggtgcag tttgtgtccc cctctgccca tcactgtgct gtgcttgttc
     2821 ctgcctctgt gccttcccct atactgctcg gacatgtccc ctttcctctc ctctacccag
     2881 ctaagccctt ctgatccacg gggcccggct tcccaaacca cccagcccac attcctcctt
     2941 cctgctccga acaggtccgg tgtgagcccc tgcccccgaa ctgcgtgctg tcccatggac
     3001 gctccagtct cttccgtgtg tgtcttgagt ccctaactag acagttagct ccctgagggc
     3061 aagggactgt catttcctct tgagtcctac cagggtctag cacaggactg ggctcctaac
     3121 tctcaggaaa cacttgtcgg ctgactggtg cctcaagcgc tggagcttgt cggtggccgg
     3181 taatgggcag tgcacgtggg gagagggtat gtgagttaac tcaagggtgc cttttcttgg
     3241 gctgtgggct ggctcccctg ggtcaaaagt ggatgtcgga ggcctcaggc tcttacctcc
     3301 ttggggcagt gggagcatca gggaccccca cccccacccc ggctctgcag gagtgcacgg
     3361 aagtggtcgt ccagcctgga tatttctaca ggttgctgac tcctgcggga gctgactgag
     3421 tggaataaat gttctctcaa catca
//
