LOCUS       NM_001365304            2323 bp    mRNA    linear   PRI 29-OCT-2022
DEFINITION  Homo sapiens uncharaterized LOC112694756 (LOC112694756), transcript
            variant 1, mRNA.
ACCESSION   NM_001365304
VERSION     NM_001365304.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2323)
  AUTHORS   Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R,
            Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T,
            Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K,
            Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T,
            Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T
            and Sugano S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
REFERENCE   2  (bases 1 to 2323)
  AUTHORS   Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
            Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
            B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
            Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
            GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
            Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
            Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
            SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
            Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
            Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
            Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
            Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
            Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
            Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
            Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093512.2.
            
            On Sep 29, 2020 this sequence version replaced NM_001365304.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC004333.1, SRR1803616.127242.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142586
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000338110.11/ ENSP00000336927.6
            NMD candidate          :: translation inferred from conservation
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                AC093512.2         121201-121267
            68-103              AC093512.2         121514-121549
            104-247             AC093512.2         122834-122977
            248-403             AC093512.2         123222-123377
            404-923             AC093512.2         131779-132298
            924-1005            AC093512.2         132474-132555
            1006-1138           AC093512.2         135284-135416
            1139-1350           AC093512.2         135500-135711
            1351-1405           AC093512.2         136696-136750
            1406-1566           AC093512.2         136868-137028
            1567-1650           AC093512.2         137356-137439
            1651-1825           AC093512.2         137549-137723
            1826-2025           AC093512.2         137880-138079
            2026-2323           AC093512.2         138167-138464
FEATURES             Location/Qualifiers
     source          1..2323
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p11.2"
     gene            1..2323
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /note="uncharaterized LOC112694756"
                     /db_xref="GeneID:112694756"
     exon            1..67
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            68..103
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     CDS             98..517
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Fructose-bisphosphate aldolase A; Lung cancer antigen
                     NY-LU-1; Muscle-type aldolase"
                     /codon_start=1
                     /product="uncharacterized protein LOC112694756 isoform 1"
                     /protein_id="NP_001352233.1"
                     /db_xref="CCDS:CCDS92136.1"
                     /db_xref="GeneID:112694756"
                     /translation="MDASSSPWNPTPAPVSSPPLLLPIPAIVFIAVGIYLLLLGLVLL
                     TRNCLLAQGCCADGSSPCRKQGSSGPPDCCWTCAEACNFPLPSPAHFLDACCPQPTRA
                     DWAPRCPRCCPLCDCACTCQLPDCQSLNCLCFEIKLR"
     exon            104..247
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            248..403
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            404..923
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1005
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1138
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1350
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1405
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1566
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            1567..1650
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1825
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..2025
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     exon            2026..2323
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2301..2306
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /note="hexamer: AATAAA"
     polyA_site      2323
                     /gene="LOC112694756"
                     /gene_synonym="ALDA; ALDOA"
                     /note="major polyA site"
ORIGIN      
        1 ggtccctcgg acgattggac ctagcttggc gcggaatccg tgaattgccc gcggcccgag
       61 ggtgcagctc ccggactgac tggctctgcc cttccccatg gacgcctcct ctagcccgtg
      121 gaatccaacc ccggctcctg tcagcagccc tcccctgctg ctccccatcc ctgccatcgt
      181 cttcatcgct gtgggcatct atttgttgct gctgggtcta gtcctgctga ctaggaactg
      241 cctgctggcc cagggctgct gcgcggacgg tagctccccc tgcaggaagc aaggttcctc
      301 cgggccccca gactgctgct ggacctgtgc agaagcctgc aactttcctc tgcctagccc
      361 ggcccacttc ctggatgctt gctgccccca gcccaccaga gctgactggg cacctcgctg
      421 cccccgctgc tgcccactct gcgactgtgc ctgtacgtgc cagctccccg actgccagag
      481 cctcaactgt ctctgcttcg agatcaagct ccgatgagga cccagggccc ctgccctctg
      541 gggagcggcc agcccccagg gcccatgtgc cctcctccct gaagagcctt tccccacgcc
      601 actggaacca cagatggcct gccgagcacc caggcctggg aactggaagt ggcagcgcag
      661 ggcctggctc cctgcagggc aggactcttg gccggctgga cggcagctcc tctggagggc
      721 cagaaaagag aggggctagt gctcgggcag gtgccctggc ttcccttccc ctccacacgt
      781 caacgattct atttgaagtt gggcaggggg gtggcgctgc tcaccacaca caagtgttat
      841 aggaggagtc tggcccttga gtaccgggta cgcaggggtg cctcaaccac actccgtcca
      901 cggactctcc gttattttag gaggtccctg gccaaagatt tatttctctt gacaaccaag
      961 ggcctccgtc tggatttcca aggaagaatt tcctctgaag caccggaact tgctactacc
     1021 agcaccatgc cctaccaata tccagcactg accccggagc agaagaagga gctgtctgac
     1081 atcgctcacc gcatcgtggc acctggcaag ggcatcctgg ctgcagatga gtccactggg
     1141 agcattgcca agcggctgca gtccattggc accgagaaca ccgaggagaa ccggcgcttc
     1201 taccgccagc tgctgctgac agctgacgac cgcgtgaacc cctgcattgg gggtgtcatc
     1261 ctcttccatg agacactcta ccagaaggcg gatgatgggc gtcccttccc ccaagttatc
     1321 aaatccaagg gcggtgttgt gggcatcaag gtagacaagg gcgtggtccc cctggcaggg
     1381 acaaatggcg agactaccac ccaagggttg gatgggctgt ctgagcgctg tgcccagtac
     1441 aagaaggacg gagctgactt cgccaagtgg cgttgtgtgc tgaagattgg ggaacacacc
     1501 ccctcagccc tcgccatcat ggaaaatgcc aatgttctgg cccgttatgc cagtatctgc
     1561 cagcagaatg gcattgtgcc catcgtggag cctgagatcc tccctgatgg ggaccatgac
     1621 ttgaagcgct gccagtatgt gaccgagaag gtgctggctg ctgtctacaa ggctctgagt
     1681 gaccaccaca tctacctgga aggcaccttg ctgaagccca acatggtcac cccaggccat
     1741 gcttgcactc agaagttttc tcatgaggag attgccatgg cgaccgtcac agcgctgcgc
     1801 cgcacagtgc cccccgctgt cactgggatc accttcctgt ctggaggcca gagtgaggag
     1861 gaggcgtcca tcaacctcaa tgccattaac aagtgccccc tgctgaagcc ctgggccctg
     1921 accttctcct acggccgagc cctgcaggcc tctgccctga aggcctgggg cgggaagaag
     1981 gagaacctga aggctgcgca ggaggagtat gtcaagcgag ccctggccaa cagccttgcc
     2041 tgtcaaggaa agtacactcc gagcggtcag gctggggctg ctgccagcga gtccctcttc
     2101 gtctctaacc acgcctatta agcggaggtg ttcccaggct gcccccaaca ctccaggccc
     2161 tgccccctcc cactcttgaa gaggaggccg cctcctcggg gctccaggct ggcttgcccg
     2221 cgctctttct tccctcgtga cagtggtgtg tggtgtcgtc tgtgaatgct aagtccatca
     2281 ccctttccgg cacactgcca aataaacagc tatttaaggg gga
//
