LOCUS       NM_001320646             945 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens U2 small nuclear RNA auxiliary factor 1 like 5
            (LOC102724594), transcript variant 1, mRNA.
ACCESSION   NM_001320646 XM_006723928 XM_006726799
VERSION     NM_001320646.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA211043.1, AL522322.3 and AI334628.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001320646.1.
            
            Transcript Variant: This variant (1) encodes isoform 1.
            
            Sequence Note: NM_001320646 is annotated on a scaffold that is
            thought to be a false duplication and thus this accession is likely
            redundant with NM_006758.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163657.230712.1,
                                           SRR1163655.342237.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                DA211043.1         37-83
            48-784              AL522322.3         1-737
            785-945             AI334628.1         9-169               c
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21p12"
     gene            1..945
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /note="U2 small nuclear RNA auxiliary factor 1 like 5"
                     /db_xref="GeneID:102724594"
     exon            1..120
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..799
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /note="isoform 1 is encoded by transcript variant 1;
                     splicing factor U2AF 35 kDa subunit; U2 small nuclear RNA
                     auxiliary factor 1-like protein 5; splicing factor U2AF 35
                     kDa subunit-like protein"
                     /codon_start=1
                     /product="splicing factor U2AF 35 kDa subunit-like protein
                     isoform 1"
                     /protein_id="NP_001307575.1"
                     /db_xref="GeneID:102724594"
                     /translation="MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQ
                     TIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVC
                     DNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEM
                     GECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGG
                     GGGGGRERDRRRSRDRERSGRF"
     exon            121..208
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /inference="alignment:Splign:2.1.0"
     exon            209..275
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /inference="alignment:Splign:2.1.0"
     exon            276..325
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /inference="alignment:Splign:2.1.0"
     exon            326..424
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /inference="alignment:Splign:2.1.0"
     exon            425..558
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /inference="alignment:Splign:2.1.0"
     exon            559..651
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /inference="alignment:Splign:2.1.0"
     exon            652..945
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      921..926
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /note="hexamer: AATAAA"
     polyA_site      945
                     /gene="LOC102724594"
                     /gene_synonym="U2AF1L5"
                     /note="major polyA site"
ORIGIN      
        1 gacgtctccc gcgggcgtcg gcagggtcgg cggcgtcggc agcagtgtcg acggcagcgg
       61 cggcggcggg tgggaaatgg cggagtatct ggcctccatc ttcggcaccg agaaagacaa
      121 agtcaactgt tcattttatt tcaaaattgg agcatgtcgt catggagaca ggtgctctcg
      181 gttgcacaat aaaccgacgt ttagccagac cattgccctc ttgaacattt accgtaaccc
      241 tcaaaactct tcccagtctg ctgacggttt gcgctgtgcc gtgagcgatg tggagatgca
      301 ggaacactat gatgagtttt ttgaggaggt ttttacagaa atggaggaga agtatgggga
      361 agtagaggag atgaacgtct gtgacaacct gggagaccac ctggtgggga acgtgtacgt
      421 caagtttcgc cgtgaggaag atgcggaaaa ggctgtgatt gacttgaata accgttggtt
      481 taatggacag ccgatccacg ccgagctgtc acccgtgacg gacttcagag aagcctgctg
      541 ccgtcagtat gagatgggag aatgcacacg aggcggcttc tgcaacttca tgcatttgaa
      601 gcccatttcc agagagctgc ggcgggagct gtatggccgc cgtcgcaaga agcatagatc
      661 aagatcccga tcccgggagc gtcgttctcg gtctagagac cgtggtcgtg gcggtggcgg
      721 tggcggtggt ggaggtggcg gcggacggga gcgtgacagg aggcggtcga gagatcgtga
      781 aagatctggg cgattctgag ccatgccatt tttaccttat gtctgctaga aagtgttgta
      841 gttgattgac caaaccagtt cataagggga atttttttta aaaaacaaca aaaaaaaaaa
      901 catacaaaga tgggtttctg aataaaattt gtagtgataa cagta
//
