LOCUS       XM_047416328            3215 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ligand of numb-protein X 1 (LNX1),
            transcript variant X3, mRNA.
ACCESSION   XM_047416328
VERSION     XM_047416328.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3215
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..3215
                     /gene="LNX1"
                     /gene_synonym="LNX; MPDZ; PDZRN2"
                     /note="ligand of numb-protein X 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 18
                     ESTs, 47 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     92 samples with support for all annotated introns"
                     /db_xref="GeneID:84708"
                     /db_xref="HGNC:HGNC:6657"
                     /db_xref="MIM:609732"
     CDS             186..2240
                     /gene="LNX1"
                     /gene_synonym="LNX; MPDZ; PDZRN2"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase LNX isoform X2"
                     /protein_id="XP_047272284.1"
                     /db_xref="GeneID:84708"
                     /db_xref="HGNC:HGNC:6657"
                     /db_xref="MIM:609732"
                     /translation="MNQPESANDPEPLCAVCGQAHSLEENHFYSYPEEVDDDLICHIC
                     LQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPMDRKPLVLQHCKKSSILVNKLLNKLL
                     VTCPFREHCTQVLQRCDLEHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLTATAP
                     SPEVSAAATISLMTDEPGLDNPAYVSSAEDGQPAISPVDSGRSNRTRARPFERSTIRS
                     RSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFPRLYHLIPDGEITSIK
                     INRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISN
                     VPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQ
                     LGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQ
                     ASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVV
                     NIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVEL
                     TEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSPSWV
                     MWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGR
                     IR"
     polyA_site      3215
                     /gene="LNX1"
                     /gene_synonym="LNX; MPDZ; PDZRN2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 acaactccgg cggcccaagg agctgctcgg ttcacccaca aggaatgaga gctgcctgcc
       61 tgctgctgct tggagagccc cagacagtcg cttgaagagg tgtgtggatg tctcctagat
      121 cttgacttgc tcctgaggaa atattgtgtg actgagtttc ctgttatact gctctccaat
      181 ccatcatgaa ccagccagag tctgccaacg atcctgaacc cctgtgtgca gtgtgtggcc
      241 aagcccactc cttggaggaa aaccacttct acagctatcc agaggaagtg gatgatgacc
      301 tcatctgcca catctgcctg caggctttgc tggaccccct ggacactccg tgtggacaca
      361 cctactgcac cctctgcctc accaacttcc tggtggagaa ggacttctgt cccatggacc
      421 gcaagcctct ggttctgcag cactgcaaga agtccagcat cctggtcaac aaactcctca
      481 acaagctact ggtgacctgc ccattcaggg agcactgcac ccaggtgttg cagcgctgtg
      541 acctcgagca tcactttcaa accagctgta aaggtgcctc ccactacggc ctgaccaaag
      601 ataggaagag gcgctcacaa gatggctgtc cagacggctg tgcgagcctc acagccacgg
      661 ctccctcccc agaggtttct gcagctgcca ccatctcctt aatgacagac gagcctggcc
      721 tagacaaccc tgcctacgtg tcctcggcag aggacgggca gccagcaatc agcccagtgg
      781 actctggccg gagcaaccga actagggcac ggccctttga gagatccact attagaagca
      841 gatcatttaa aaaaataaat cgagctttga gtgttcttcg aaggacaaag agcgggagtg
      901 cagttgccaa ccatgccgac cagggcaggg aaaattctga aaacaccact gcccctgaag
      961 tctttccaag gttgtaccac ctgattccag atggtgaaat taccagcatc aagatcaatc
     1021 gagtagatcc cagtgaaagc ctctctatta ggctggtggg aggtagcgaa accccactgg
     1081 tccatatcat tatccaacac atttatcgtg atggggtgat cgccagagac ggccggctac
     1141 tgccaggaga catcattcta aaggtcaacg ggatggacat cagcaatgtc cctcacaact
     1201 acgctgtgcg tctcctgcgg cagccctgcc aggtgctgtg gctgactgtg atgcgtgaac
     1261 agaagttccg cagcaggaac aatggacagg ccccggatgc ctacagaccc cgagatgaca
     1321 gctttcatgt gattctcaac aaaagtagcc ccgaggagca gcttggaata aaactggtgc
     1381 gcaaggtgga tgagcctggg gttttcatct tcaatgtgct ggatggcggt gtggcatatc
     1441 gacatggtca gcttgaggag aatgaccgtg tgttagccat caatggacat gatcttcgat
     1501 atggcagccc agaaagtgcg gctcatctga ttcaggccag tgaaagacgt gttcacctcg
     1561 tcgtgtcccg ccaggttcgg cagcggagcc ctgacatctt tcaggaagcc ggctggaaca
     1621 gcaatggcag ctggtcccca gggccagggg agaggagcaa cactcccaag cccctccatc
     1681 ctacaattac ttgtcatgag aaggtggtaa atatccaaaa agaccccggt gaatctctcg
     1741 gcatgaccgt cgcaggggga gcatcacata gagaatggga tttgcctatc tatgtcatca
     1801 gtgttgagcc cggaggagtc ataagcagag atggaagaat aaaaacaggt gacattttgt
     1861 tgaatgtgga tggggtcgaa ctgacagagg tcagccggag tgaggcagtg gcattattga
     1921 aaagaacatc atcctcgata gtactcaaag ctttggaagt caaagagtat gagccccagg
     1981 aagactgcag cagcccagca gccctggact ccaaccacaa catggcccca cccagtgact
     2041 ggtccccatc ctgggtcatg tggctggaat taccacggtg cttgtataac tgtaaagata
     2101 ttgtattacg aagaaacaca gctggaagtc tgggcttctg cattgtagga ggttatgaag
     2161 aatacaatgg aaacaaacct tttttcatca aatccattgt tgaaggaaca ccagcataca
     2221 atgatggaag aattaggtaa taataatgac taatcaaaaa tacttgtatt aaatgttgtt
     2281 tcataaatgc caaagcttgg ccccatttga gataaggcat gtatttatta tactttgtgg
     2341 ggattaaaag tatgtacgta gcattcaact tctgagaaat ccaaaataat tacacatatt
     2401 cttggtccca tactacaact ccccatactt ttagcattcc ttctaacaca agctgaatgg
     2461 atagtgagtt tggagaatgt aaataagagg caagaaatat ctcaattaga agttaacata
     2521 attaaaatgg tcagatgtag caaaatctag caccactaag ataaacttgc attaacttca
     2581 gcaacgaatt aaaatactaa tcatatcttg ttttgttttt ttttttagat gtggtgatat
     2641 tcttcttgct gtcaatggta gaagtacatc aggaatgata catgcttgct tggcaagact
     2701 gctgaaagaa cttaaaggaa gaattactct aactattgtt tcttggcctg gcactttttt
     2761 atagaatcaa tgatgggtca gaggaaaaca gaaaaatcac aaataggcta agaagttgaa
     2821 acactatatt tatcttgtca gtttttatat ttaaagaaag aatacattgt aaaaatgtca
     2881 ggaaaagtat gatcatctaa tgaaagccag ttacacctca gaaaatatga ttccaaaaaa
     2941 attaaaacta ctagtttttt ttcagtgtgg aggatttctc attactctac aacattgttt
     3001 atattttttc tattcaataa aaagccctaa aacaactaaa atgatttgta taccccactg
     3061 aattcaagct gatttaaatt taaaatttgg tatatgctga agtctgccaa gggtacatta
     3121 tggccatttt taatttacag ctaaaatatt ttttaaaatg cattgctgag aaacgttgct
     3181 ttcatcaaac aagaataaat atttttcaga agtta
//
