LOCUS       XM_005265785            4189 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ligand of numb-protein X 1 (LNX1),
            transcript variant X2, mRNA.
ACCESSION   XM_005265785
VERSION     XM_005265785.6
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005265785.5.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4189
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..4189
                     /gene="LNX1"
                     /gene_synonym="LNX; MPDZ; PDZRN2"
                     /note="ligand of numb-protein X 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 32
                     ESTs, 234 long SRA reads, 5 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 21 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:84708"
                     /db_xref="HGNC:HGNC:6657"
                     /db_xref="MIM:609732"
     CDS             397..2583
                     /gene="LNX1"
                     /gene_synonym="LNX; MPDZ; PDZRN2"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase LNX isoform X1"
                     /protein_id="XP_005265842.1"
                     /db_xref="GeneID:84708"
                     /db_xref="HGNC:HGNC:6657"
                     /db_xref="MIM:609732"
                     /translation="MNQPESANDPEPLCAVCGQAHSLEENHFYSYPEEVDDDLICHIC
                     LQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPMDRKPLVLQHCKKSSILVNKLLNKLL
                     VTCPFREHCTQVLQRCDLEHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLTATAP
                     SPEVSAAATISLMTDEPGLDNPAYVSSAEDGQPAISPVDSGRSNRTRARPFERSTIRS
                     RSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFPRLYHLIPDGEITSIK
                     INRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISN
                     VPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQ
                     LGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQ
                     ASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVV
                     NIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVEL
                     TEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSPSWV
                     MWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGR
                     IRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL"
ORIGIN      
        1 agaagagatt tgtcactgat gctaatgcat gctgctctgc aggggaccac tctccctcga
       61 agctccccat agctgctctc agttttatgg atctgctcta ctcaaagcct tgcagaaggg
      121 gcaggggatg cccaggttaa cccccgcacg tacaaaggtg gagcagtttt catgcatagc
      181 tgggacgaag aacactggaa agagaaagaa aaattttccg agctactgct aagccagaaa
      241 agctcagctc tcaaacggac tatctcctga gacgtcacac agctgggaac tgatccgcaa
      301 tacagcaaag gtgtgtggat gtctcctaga tcttgacttg ctcctgagga aatattgtgt
      361 gactgagttt cctgttatac tgctctccaa tccatcatga accagccaga gtctgccaac
      421 gatcctgaac ccctgtgtgc agtgtgtggc caagcccact ccttggagga aaaccacttc
      481 tacagctatc cagaggaagt ggatgatgac ctcatctgcc acatctgcct gcaggctttg
      541 ctggaccccc tggacactcc gtgtggacac acctactgca ccctctgcct caccaacttc
      601 ctggtggaga aggacttctg tcccatggac cgcaagcctc tggttctgca gcactgcaag
      661 aagtccagca tcctggtcaa caaactcctc aacaagctac tggtgacctg cccattcagg
      721 gagcactgca cccaggtgtt gcagcgctgt gacctcgagc atcactttca aaccagctgt
      781 aaaggtgcct cccactacgg cctgaccaaa gataggaaga ggcgctcaca agatggctgt
      841 ccagacggct gtgcgagcct cacagccacg gctccctccc cagaggtttc tgcagctgcc
      901 accatctcct taatgacaga cgagcctggc ctagacaacc ctgcctacgt gtcctcggca
      961 gaggacgggc agccagcaat cagcccagtg gactctggcc ggagcaaccg aactagggca
     1021 cggccctttg agagatccac tattagaagc agatcattta aaaaaataaa tcgagctttg
     1081 agtgttcttc gaaggacaaa gagcgggagt gcagttgcca accatgccga ccagggcagg
     1141 gaaaattctg aaaacaccac tgcccctgaa gtctttccaa ggttgtacca cctgattcca
     1201 gatggtgaaa ttaccagcat caagatcaat cgagtagatc ccagtgaaag cctctctatt
     1261 aggctggtgg gaggtagcga aaccccactg gtccatatca ttatccaaca catttatcgt
     1321 gatggggtga tcgccagaga cggccggcta ctgccaggag acatcattct aaaggtcaac
     1381 gggatggaca tcagcaatgt ccctcacaac tacgctgtgc gtctcctgcg gcagccctgc
     1441 caggtgctgt ggctgactgt gatgcgtgaa cagaagttcc gcagcaggaa caatggacag
     1501 gccccggatg cctacagacc ccgagatgac agctttcatg tgattctcaa caaaagtagc
     1561 cccgaggagc agcttggaat aaaactggtg cgcaaggtgg atgagcctgg ggttttcatc
     1621 ttcaatgtgc tggatggcgg tgtggcatat cgacatggtc agcttgagga gaatgaccgt
     1681 gtgttagcca tcaatggaca tgatcttcga tatggcagcc cagaaagtgc ggctcatctg
     1741 attcaggcca gtgaaagacg tgttcacctc gtcgtgtccc gccaggttcg gcagcggagc
     1801 cctgacatct ttcaggaagc cggctggaac agcaatggca gctggtcccc agggccaggg
     1861 gagaggagca acactcccaa gcccctccat cctacaatta cttgtcatga gaaggtggta
     1921 aatatccaaa aagaccccgg tgaatctctc ggcatgaccg tcgcaggggg agcatcacat
     1981 agagaatggg atttgcctat ctatgtcatc agtgttgagc ccggaggagt cataagcaga
     2041 gatggaagaa taaaaacagg tgacattttg ttgaatgtgg atggggtcga actgacagag
     2101 gtcagccgga gtgaggcagt ggcattattg aaaagaacat catcctcgat agtactcaaa
     2161 gctttggaag tcaaagagta tgagccccag gaagactgca gcagcccagc agccctggac
     2221 tccaaccaca acatggcccc acccagtgac tggtccccat cctgggtcat gtggctggaa
     2281 ttaccacggt gcttgtataa ctgtaaagat attgtattac gaagaaacac agctggaagt
     2341 ctgggcttct gcattgtagg aggttatgaa gaatacaatg gaaacaaacc ttttttcatc
     2401 aaatccattg ttgaaggaac accagcatac aatgatggaa gaattagatg tggtgatatt
     2461 cttcttgctg tcaatggtag aagtacatca ggaatgatac atgcttgctt ggcaagactg
     2521 ctgaaagaac ttaaaggaag aattactcta actattgttt cttggcctgg cactttttta
     2581 tagaatcaat gatgggtcag aggaaaacag aaaaatcaca aataggctaa gaagttgaaa
     2641 cactatattt atcttgtcag tttttatatt taaagaaaga atacattgta aaaatgtcag
     2701 gaaaagtatg atcatctaat gaaagccagt tacacctcag aaaatatgat tccaaaaaaa
     2761 ttaaaactac tagttttttt tcagtgtgga ggatttctca ttactctaca acattgttta
     2821 tattttttct attcaataaa aagccctaaa acaactaaaa tgatttgtat accccactga
     2881 attcaagctg atttaaattt aaaatttggt atatgctgaa gtctgccaag ggtacattat
     2941 ggccattttt aatttacagc taaaatattt tttaaaatgc attgctgaga aacgttgctt
     3001 tcatcaaaca agaataaata tttttcagaa gttatagttg tcttttagta tgtgatacta
     3061 attaagatta cttttgtatt atcactattt aaaagatcct agtaatttat tctttcaaat
     3121 accatgttat ttgttaccat caccgatgaa tacctcctag gcttatccct aaaaatgctc
     3181 gctcagagaa ttaattataa acttgttttg tttttagtaa gaaatggcta aagctctttt
     3241 tttccacaat cgttagtaac tgtataaaaa ctcatgctgc tccaccagtg ggccttggaa
     3301 aatgcatcaa gaaggccaaa ccagcttgac cctggctcac agacatggtc atgaggcgat
     3361 ttaaatttgt gccacaatga agagtgtgtg tacacatgcc tcctagaaac tacactatgg
     3421 gtaattaatt aatttatttc atagaggcca cccagatgcc ttataggttt tattaatttg
     3481 gatatgaaag tgtaccccat ttggtttcac caggaaccca aatttagaat attgaaaagc
     3541 catcaaaaag ttgtgatatc aaaaatgtat gagtctctta atatactaag caagagtgtc
     3601 acagcagtaa tgataaagac tagttttaat ctcaagcctt agaggggccc tttgttgcct
     3661 tttgtgatgc agcctcttaa gagagtggtg tttgattaac aaaaaaactg tggcccaagt
     3721 ggaacccttg accttttctc agataatctg tgtatgtaca cagctaacac agctctttag
     3781 attccctgtt aagtgactca ttcacattcc tttcttggat ataaagtcat tgctgtcttt
     3841 ttatttttga aatagtacaa gacaaagatt tttaacttaa catgaaaaat tcactctttt
     3901 attttggaaa aaaagttaac ttttcatact aacaaacaga acaagattta aggtaaattt
     3961 cttaaacatt atccagaaaa ataacaagat ttatagtatc tacttctggt actaatatac
     4021 acaaaaggcc aaaaccatgc ctattctgca ggtgtagctt cggtgctctc ctgttcaggg
     4081 gcaggctcac tgcccgcttc ttttccttct ttgcttcttt tagatttttt gtgtttgtgt
     4141 ctcctgtgac tatctccttc ttcactttca tggcgacgtc tactattac
//
