LOCUS       NM_173573               2057 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens lamin tail domain containing 2 (LMNTD2), mRNA.
ACCESSION   NM_173573
VERSION     NM_173573.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2057)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC039077.1, BX384085.2, AP006284.2, BX384084.2 and AI539379.1.
            
            On Nov 22, 2018 this sequence version replaced NM_173573.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC039077.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000329451.8/ ENSP00000331167.3
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-151               BC039077.1         42-192
            152-742             BX384085.2         296-886
            743-975             BC039077.1         784-1016
            976-976             AP006284.2         15574-15574         c
            977-1065            BC039077.1         1018-1106
            1066-1071           BX384084.2         950-955             c
            1072-2050           BC039077.1         1113-2091
            2051-2057           AI539379.1         4-10                c
FEATURES             Location/Qualifiers
     source          1..2057
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.5"
     gene            1..2057
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /note="lamin tail domain containing 2"
                     /db_xref="GeneID:256329"
                     /db_xref="HGNC:HGNC:28561"
     exon            1..56
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..1927
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /codon_start=1
                     /product="lamin tail domain-containing protein 2"
                     /protein_id="NP_775844.2"
                     /db_xref="CCDS:CCDS7701.1"
                     /db_xref="GeneID:256329"
                     /db_xref="HGNC:HGNC:28561"
                     /translation="MRWLRPAGRRREQESVSGHLGPPAGAPAAPETPTCLPDTTPHPA
                     PVVCSADPQLALESLDPRTLRLLWRQRELEIQALRWAIQNGEDARLCHILEEVAGLPP
                     KRSSHSQEKLLQNQVQKLIQELKEQKERAQWEKEHLEERLLQTTRTLQEMEAELQNLQ
                     KSCLLQLARSSWVGRMLRSQTGSVEVVTAETLMDPSDLSENIQAPTGEGFRLEDVDWN
                     SVARRYPNLFTNMEPSSKQKQPRPWPQLDTGSPESSGKHSERHHKTVEWGSLPCLNTS
                     SSGGADSDSSSCRPGLPSFVQVIGHPPRDHRASSEQALVQAGSYSRDSEDLQKTHSPR
                     HGEPVLSPQPCTDPDHWSPELLQSPTGLKIVAVSCREKFVRIFNPSQESTADLSGMVL
                     KQLVRGFPERLYRFPPGTLLAPRHHVTVWGEATRSAKKPLRASSSREPVPLLSIRGCA
                     TLLLSPKGEVLSEHRIPRRETPAPRVFADGTDLSIDRFPLPEAGPGADTRKPPRPPRP
                     LRKGRVREPRVSRRRPGTRGLLPPVSSGKLFHAREGPARPENPEIPAPQHLPAIPGDP
                     TLPSPPAEAGLGLEDCRLQKEHRVRVCRKSVDRSCPLVALSVQNTAESRFGFRFLSCL
                     PVTADTCRGA"
     exon            57..180
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            181..333
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            334..421
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            422..577
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            578..646
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            647..735
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            736..998
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1095
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1279
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1399
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1596
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1795
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     exon            1796..2057
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2032..2037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /note="hexamer: AGTAAA"
     polyA_site      2057
                     /gene="LMNTD2"
                     /gene_synonym="C11orf35"
                     /note="major polyA site"
ORIGIN      
        1 gcctaccgcg aaaaacgcgg aaatgcggtg gctgcggccc gcgggcaggc gtcgggagca
       61 agagtcggtc agtggtcacc tgggacctcc agcaggcgca cctgcagccc ccgagactcc
      121 cacgtgcctg ccagacacca cgccccaccc cgcaccggtg gtctgctctg ccgacccgca
      181 gttggctctt gagtccctgg accctcgcac actgcggctg ctgtggagac agcgagaact
      241 ggagatccag gccttgcggt gggccatcca gaatggcgag gacgcccggc tctgccacat
      301 cctggaagag gtggcggggc ttccgcccaa gaggagctcc cacagtcagg agaaactcct
      361 gcagaaccag gtccagaagc tgatccagga gttgaaggaa cagaaggagc gagcccagtg
      421 ggagaaggag cacctggagg agcggctgct gcagaccacc cgcacgctcc aggagatgga
      481 ggccgagctg cagaacttgc agaagtcctg cctcctgcag ctggcccgct cctcgtgggt
      541 gggccgcatg ctacgatccc agactggcag tgtggaggta gtgacggcag agactctgat
      601 ggacccaagc gacctctctg aaaacattca ggcccccacc ggggagggct ttcggctgga
      661 ggacgtggat tggaacagcg ttgcccgccg gtatcccaac ctcttcacca acatggagcc
      721 cagctcaaag caaaagcagc cccggccctg gccacagctg gacacaggga gcccagagtc
      781 ctctggaaag cattccgagc ggcatcacaa gaccgtggag tggggctccc tgccctgtct
      841 gaacaccagc agctcagggg gcgctgactc cgactccagc agctgccggc cgggcctgcc
      901 ttccttcgtg caggtgatag ggcacccgcc ccgggaccac cgcgcttcct ccgagcaagc
      961 gctggtgcag gccggcagct acagcaggga ctcagaagat ctccagaaaa cccactcacc
     1021 caggcacggc gagccggtcc tgtcgcccca gccctgcaca gacccggacc actggagccc
     1081 ggaactcctg cagagcccga caggcctgaa gatcgtggct gtgagctgcc gggagaagtt
     1141 cgtccgcatc ttcaacccgt cgcaggagag cacggccgac ctgagcggca tggtgctgaa
     1201 gcagctggtg cgcggcttcc cggagcgcct gtaccgcttc ccgccgggca cgctgctggc
     1261 cccgcggcac cacgtcacgg tctggggcga ggcgacccgc agcgccaaga agccgctgcg
     1321 cgcgtcctcg agccgggagc ccgttcccct cctctccatc cgcggctgcg cgacgctgct
     1381 cctgagcccc aagggcgagg tcctcagtga gcaccggatc ccacgccgcg agactccggc
     1441 cccgagggtc ttcgccgacg gcaccgactt gtccatcgac cgcttcccgc tccctgaggc
     1501 cgggcccggc gccgacaccc gcaagccgcc gcgcccacct cgacccctgc gcaaaggccg
     1561 ggtgcgggag ccccgggtca gtcgccggag accagggacg cggggcctgc tgcccccagt
     1621 gagctcgggg aagctcttcc acgcgcggga ggggcctgcg cggcccgaga accccgagat
     1681 ccccgcgccg cagcacctgc ccgccatccc gggtgacccc accctgccgt cgcctcccgc
     1741 agaggccggg ctgggcctgg aggactgtcg gctccagaaa gaacaccgag ttcgggtgtg
     1801 ccggaagagc gtggaccgta gctgccccct ggtggccctg tcggtgcaga acacggcgga
     1861 gagcagattc ggcttccgct tcctcagctg cctgccggtc accgcggaca cctgccgcgg
     1921 cgcctagggg cggaggagtg gggccgggac cgcgagggag ggcgcgggcg ggcgccgggg
     1981 ctgggcgggc tgtgtccgct gcatcattta ttgaaccaac gtggcctaca aagtaaaccg
     2041 catttctgta cacctga
//
