LOCUS       NM_001145728            1876 bp    mRNA    linear   PRI 08-FEB-2024
DEFINITION  Homo sapiens lamin tail domain containing 1 (LMNTD1), transcript
            variant 1, mRNA.
ACCESSION   NM_001145728
VERSION     NM_001145728.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1876)
  AUTHORS   Wang,M., Futamura,M., Wang,Y. and You,M.
  TITLE     Pas1c1 is a candidate for the mouse pulmonary adenoma
            susceptibility 1 locus
  JOURNAL   Oncogene 24 (11), 1958-1963 (2005)
   PUBMED   15688036
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK302292.1, DB039294.1, DW009862.1 and AK093323.1.
            
            On Jan 14, 2012 this sequence version replaced NM_001145728.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK302292.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000458174.7/ ENSP00000407353.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                AK302292.1         1-83
            84-195              DB039294.1         34-145
            196-1403            AK302292.1         196-1403
            1404-1404           DW009862.1         419-419
            1405-1677           AK302292.1         1405-1677
            1678-1876           AK093323.1         1520-1718
FEATURES             Location/Qualifiers
     source          1..1876
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p12.1"
     gene            1..1876
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /note="lamin tail domain containing 1"
                     /db_xref="GeneID:160492"
                     /db_xref="HGNC:HGNC:26683"
                     /db_xref="MIM:617254"
     exon            1..215
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
     exon            216..334
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..1475
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     intermediate filament tail domain-containing protein 1;
                     intermediate filament tail domain containing 1; lamin tail
                     domain-containing protein 1"
                     /codon_start=1
                     /product="lamin tail domain-containing protein 1 isoform
                     1"
                     /protein_id="NP_001139200.1"
                     /db_xref="CCDS:CCDS44849.1"
                     /db_xref="GeneID:160492"
                     /db_xref="HGNC:HGNC:26683"
                     /db_xref="MIM:617254"
                     /translation="MKDTQDIQEASKAMQNKVHEQEDKNEKQKQREDKLGVYSLVHFS
                     PKMLGSVATTLPLSSSNSSGMPLGYYLSSPQISRVTISTTGQLTSKATVGSCSRVENS
                     LDASPFSVPKKQDESPMIGDGEDYFLSLFGDSKKLTAHSNYTQKTLKYFSMILEEVGQ
                     FTSSSLGDVEIAEVNVKGLFVKLINSSLDKEMAIGDHILQQNVNGQTISLYRFLPNIV
                     MQANSTVTVWAAASEAKHQPPSDFLWKEQDKFRASPDCITILCKPNGQAIAWYTPIHW
                     KQAWEKLDADVEFNRCSVVSPTFRKRVFQWTASTATITKEKQDQPKKDISNYQVEQAQ
                     VLLKREKEIPPTVFPNRSPWCQNPYVSAHPYCPLIEPHNTSTAGGRLDRQPRTRSTRP
                     NRASGSKKKKTSESQKQ"
     exon            335..555
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
     exon            556..736
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
     exon            737..923
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1043
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1261
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1434
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1497
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
     exon            1498..1876
                     /gene="LMNTD1"
                     /gene_synonym="IFLTD1; LMNARS1; PAS1C1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtagtcataa aggtctcttt gccaagttac tgccctctca agctgcttcc agtgaatgct
       61 acacacctgc accatggttt gtccgacatc cttagccaag atcaggattg gctatgttgg
      121 tacttacata tcctcatgag aattgtggtt ctggtactag tttggtaaag aaattattaa
      181 acctagctga tgcttgaagg tagttggatt aacaggaaag aaaagagact tcttttctag
      241 ccaagatgaa agatacacaa gacattcagg aagcttcgaa ggcaatgcag aataaagtcc
      301 atgagcagga agataagaat gagaaacaaa aacaaagaga agacaaactt ggagtatatt
      361 ctttagtaca tttttcccca aagatgttgg gttcagttgc cacaacactg ccattgtcat
      421 cttcaaattc cagtggaatg cctcttggtt actatctgtc tagtcctcag attagtagag
      481 taactatatc aacaactgga caattgactt ctaaagctac tgtaggtagc tgttccagag
      541 tggaaaacag cttggatgcc agccccttct cagttccgaa gaaacaggat gaatcaccca
      601 tgattgggga tggagaagat tatttccttt ctttgtttgg tgattcaaag aaacttacag
      661 cacactcaaa ctacactcag aaaactttaa aatacttttc tatgattctt gaagaagttg
      721 gccaatttac ctccagttct cttggagatg ttgaaatagc tgaagtgaat gtcaagggtt
      781 tgttcgtgaa gctcattaac tcttcccttg acaaagaaat ggcaattgga gatcatattc
      841 tccagcaaaa tgtgaatgga caaaccattt ctttgtaccg attccttcca aacatcgtaa
      901 tgcaggcaaa ttccacagta acagtgtggg cagcagcatc tgaagcaaag catcaacctc
      961 catcagattt tctttggaag gaacaagaca agtttagagc aagtcctgat tgtataacaa
     1021 tcctgtgcaa accgaacggt caagccattg cgtggtacac ccctatccac tggaagcaag
     1081 cgtgggaaaa attagatgct gacgttgaat ttaacagatg ttcagtagta tctccaacat
     1141 tccgaaagcg tgtgtttcag tggacagcat ctacagctac aataactaaa gaaaaacaag
     1201 atcaacctaa gaaagatatc tcaaattatc aggtggaaca agctcaagtt cttcttaaga
     1261 gagagaagga aatcccacca accgttttcc ctaatcgcag cccttggtgc cagaatccct
     1321 atgtctctgc acatccttac tgtcctctga ttgaaccaca caatacatcc accgctggag
     1381 gcagattgga tagacagccc aggactcggt caaccagacc taatcgagcc tcagggtcta
     1441 agaaaaagaa gacatctgag tcacaaaagc aataagcagt caactcaacc tttaaagtaa
     1501 tctagtccac cctcaaccag ctactagaaa agcaaaagag aactcaaatc cctgaggcct
     1561 gctctgcaac ctccctgcta ttccatgaga gggtgaagac atcacatttc tatatggaaa
     1621 aaggatccaa aatttgtatt gctgtagaat tggtgaatta tagatgcttg atgaaatcac
     1681 aagtcctacc actcctgcct tccaaatccc tgcagaaaac aagcagatgg ttagtattat
     1741 tcaatggata aaattgctat ttgccttaga tttctctttt tgtaaacaaa gttattttgg
     1801 gtacagaact cacaaaagaa gagcacgtgc aattgtttaa ccattttaca ttgactgata
     1861 aatctctttt ttccat
//
