LOCUS       NM_201544               5957 bp    mRNA    linear   PRI 10-FEB-2025
DEFINITION  Homo sapiens galectin 8 (LGALS8), transcript variant 3, mRNA.
ACCESSION   NM_201544
VERSION     NM_201544.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5957)
  AUTHORS   Legner,J., Jovanovic Krivokuca,M., Vilotic,A., Pirkovic,A.,
            Nacka-Aleksic,M. and Bojic-Trbojevic,Z.
  TITLE     Galectin-8 Contributes to Human Trophoblast Cell Invasion
  JOURNAL   Int J Mol Sci 25 (18), 10096 (2024)
   PUBMED   39337581
  REMARK    GeneRIF: Galectin-8 Contributes to Human Trophoblast Cell Invasion.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5957)
  AUTHORS   Beyer,S., Wehrmann,M., Meister,S., Trillsch,F., Ganster,F.,
            Schmoeckel,E., Corradini,S., Mahner,S., Jeschke,U., Kessler,M.,
            Burges,A. and Kolben,T.
  TITLE     Expression of Intracellular Galectin-8 and -9 in Endometrial Cancer
  JOURNAL   Int J Mol Sci 25 (13), 6907 (2024)
   PUBMED   39000016
  REMARK    GeneRIF: Expression of Intracellular Galectin-8 and -9 in
            Endometrial Cancer.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5957)
  AUTHORS   Liu,D., Zhu,H., Cheng,L., Li,R., Ma,X., Wang,J., Wang,J., Zhang,S.,
            Li,Y., Shu,K., Yu,X. and Li,C.
  TITLE     Hypoxia-induced galectin-8 maintains stemness in glioma stem cells
            via autophagy regulation
  JOURNAL   Neuro Oncol 26 (5), 872-888 (2024)
   PUBMED   38158714
  REMARK    GeneRIF: Hypoxia-induced galectin-8 maintains stemness in glioma
            stem cells via autophagy regulation.
REFERENCE   4  (bases 1 to 5957)
  AUTHORS   Xia,B., Lu,Y., Liang,J., Li,F., Peng,J., Wang,J., Wan,C., Ding,J.,
            Le,C., Dai,J., Guo,B. and Shen,Z.
  TITLE     Association of GAL-8 promoter methylation levels with coronary
            plaque inflammation
  JOURNAL   Int J Cardiol 401, 131782 (2024)
   PUBMED   38246423
  REMARK    GeneRIF: Association of GAL-8 promoter methylation levels with
            coronary plaque inflammation.
REFERENCE   5  (bases 1 to 5957)
  AUTHORS   Roy,M., Mbous Nguimbus,L., Badiane,P.Y., Goguen-Couture,V.,
            Degrandmaison,J., Parent,J.L., Brunet,M.A. and Roux,S.
  TITLE     Galectin-8 modulates human osteoclast activity partly through
            isoform-specific interactions
  JOURNAL   Life Sci Alliance 7 (5), e202302348 (2024)
   PUBMED   38395460
  REMARK    GeneRIF: Galectin-8 modulates human osteoclast activity partly
            through isoform-specific interactions.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5957)
  AUTHORS   Bidon,N., Brichory,F., Bourguet,P., Le Pennec,J.P. and Dazord,L.
  TITLE     Galectin-8: a complex sub-family of galectins (Review)
  JOURNAL   Int J Mol Med 8 (3), 245-250 (2001)
   PUBMED   11494049
  REMARK    Review article
REFERENCE   7  (bases 1 to 5957)
  AUTHORS   Gopalkrishnan,R.V., Roberts,T., Tuli,S., Kang,D., Christiansen,K.A.
            and Fisher,P.B.
  TITLE     Molecular characterization of prostate carcinoma tumor antigen-1,
            PCTA-1, a human galectin-8 related gene
  JOURNAL   Oncogene 19 (38), 4405-4416 (2000)
   PUBMED   10980616
REFERENCE   8  (bases 1 to 5957)
  AUTHORS   Hadari,Y.R., Arbel-Goren,R., Levy,Y., Amsterdam,A., Alon,R.,
            Zakut,R. and Zick,Y.
  TITLE     Galectin-8 binding to integrins inhibits cell adhesion and induces
            apoptosis
  JOURNAL   J Cell Sci 113 (Pt 13), 2385-2397 (2000)
   PUBMED   10852818
REFERENCE   9  (bases 1 to 5957)
  AUTHORS   Bassen,R., Brichory,F., Caulet-Maugendre,S., Bidon,N., Delaval,P.,
            Desrues,B. and Dazord,L.
  TITLE     Expression of Po66-CBP, a type-8 galectin, in different healthy,
            tumoral and peritumoral tissues
  JOURNAL   Anticancer Res 19 (6B), 5429-5433 (1999)
   PUBMED   10697573
REFERENCE   10 (bases 1 to 5957)
  AUTHORS   Su,Z.Z., Lin,J., Shen,R., Fisher,P.E., Goldstein,N.I. and
            Fisher,P.B.
  TITLE     Surface-epitope masking and expression cloning identifies the human
            prostate carcinoma tumor antigen gene PCTA-1 a member of the
            galectin gene family
  JOURNAL   Proc Natl Acad Sci U S A 93 (14), 7252-7257 (1996)
   PUBMED   8692978
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC016486.2 and AL359921.13.
            
            On Feb 27, 2020 this sequence version replaced NM_201544.3.
            
            Summary: This gene encodes a member of the galectin family.
            Galectins are beta-galactoside-binding animal lectins with
            conserved carbohydrate recognition domains. The galectins have been
            implicated in many essential functions including development,
            differentiation, cell-cell adhesion, cell-matrix interaction,
            growth regulation, apoptosis, and RNA splicing. This gene is widely
            expressed in tumoral tissues and seems to be involved in
            integrin-like cell interactions. Alternatively spliced transcript
            variants encoding different isoforms have been identified.
            [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (3) differs in the 5' UTR and
            lacks an in-frame segment of the coding region, compared to variant
            1. Variants 2 and 3 encode a shorter isoform (b) that is missing an
            internal segment compared to isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            CCDS Note: This CCDS representation uses the 5'-most in-frame start
            codon, which is conserved in higher primates. An alternative
            downstream start codon, which is more widely conserved, also
            exists. It is possible that leaky scanning by ribosomes would allow
            the downstream start codon to be used, at least some of the time.
            The use of the downstream start codon would result in a protein
            that is 1 aa shorter at the N-terminus. There is no experimental
            evidence showing which start codon is preferentially used in vivo.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB209914.1, SRR1803615.9947.1
                                           [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000366584.9/ ENSP00000355543.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1403              BC016486.2         206-1608
            1404-5957           AL359921.13        25528-30081
FEATURES             Location/Qualifiers
     source          1..5957
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q43"
     gene            1..5957
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /note="galectin 8"
                     /db_xref="GeneID:3964"
                     /db_xref="HGNC:HGNC:6569"
                     /db_xref="MIM:606099"
     exon            1..80
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     exon            81..228
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     CDS             184..1137
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /note="isoform b is encoded by transcript variant 3; Po66
                     carbohydrate binding protein; prostate carcinoma tumor
                     antigen 1; galectin-8g; po66 carbohydrate-binding protein;
                     lectin, galactoside-binding, soluble, 8"
                     /codon_start=1
                     /product="galectin-8 isoform b"
                     /protein_id="NP_963838.1"
                     /db_xref="CCDS:CCDS1612.1"
                     /db_xref="GeneID:3964"
                     /db_xref="HGNC:HGNC:6569"
                     /db_xref="MIM:606099"
                     /translation="MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDAD
                     RFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKS
                     FEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQST
                     QASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDL
                     LAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVR
                     EFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW"
     exon            229..317
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     exon            318..528
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     exon            529..648
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     exon            649..705
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     exon            706..732
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     exon            733..821
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     exon            822..987
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     exon            988..5957
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1260
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /note="major polyA site"
     regulatory      2215..2220
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /note="hexamer: ATTAAA"
     polyA_site      2245
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /note="major polyA site"
     regulatory      5375..5380
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /note="hexamer: AATAAA"
     polyA_site      5399
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /note="major polyA site"
     regulatory      5921..5926
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /note="hexamer: AATAAA"
     regulatory      5938..5943
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
                     /note="hexamer: AATAAA"
     polyA_site      5948
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
     polyA_site      5957
                     /gene="LGALS8"
                     /gene_synonym="Gal-8; PCTA-1; PCTA1; Po66-CBP"
ORIGIN      
        1 gccagagccg ggaaccctga cggcacttag ctgctgacaa acaacctgct ccgtggagcg
       61 cctgaaacac cagtctttgg ggccagtgcc tcagtttcaa tccaggtaac ctttaaatga
      121 aacttgccta aaatcttagg tcatacacag aagagactcc aatcgacaag aagctggaaa
      181 agaatgatgt tgtccttaaa caacctacag aatatcatct ataacccggt aatcccgttt
      241 gttggcacca ttcctgatca gctggatcct ggaactttga ttgtgatacg tgggcatgtt
      301 cctagtgacg cagacagatt ccaggtggat ctgcagaatg gcagcagcat gaaacctcga
      361 gccgatgtgg cctttcattt caatcctcgt ttcaaaaggg ccggctgcat tgtttgcaat
      421 actttgataa atgaaaaatg gggacgggaa gagatcacct atgacacgcc tttcaaaaga
      481 gaaaagtctt ttgagatcgt gattatggtg ctgaaggaca aattccaggt ggctgtaaat
      541 ggaaaacata ctctgctcta tggccacagg atcggcccag agaaaataga cactctgggc
      601 atttatggca aagtgaatat tcactcaatt ggttttagct tcagctcgga cttacaaagt
      661 acccaagcat ctagtctgga actgacagag ataagtagag aaaatgttcc aaagtctggc
      721 acgccccagc ttaggctgcc attcgctgca aggttgaaca cccccatggg ccctggacga
      781 actgtcgtcg ttaaaggaga agtgaatgca aatgccaaaa gctttaatgt tgacctacta
      841 gcaggaaaat caaaggatat tgctctacac ttgaacccac gcctgaatat taaagcattt
      901 gtaagaaatt cttttcttca ggagtcctgg ggagaagaag agagaaatat tacctctttc
      961 ccatttagtc ctgggatgta ctttgagatg ataatttatt gtgatgttag agaattcaag
     1021 gttgcagtaa atggcgtaca cagcctggag tacaaacaca gatttaaaga gctcagcagt
     1081 attgacacgc tggaaattaa tggagacatc cacttactgg aagtaaggag ctggtagcct
     1141 acctacacag ctgctacaaa aaccaaaata cagaatggct tctgtgatac tggccttgct
     1201 gaaacgcatc tcactgtcat tctattgttt atattgttaa aatgagcttg tgcaccatta
     1261 ggtcctgctg ggtgttctca gtccttgcca tgaagtatgg tggtgtctag cactgaatgg
     1321 ggaaactggg ggcagcaaca cttatagcca gttaaagcca ctctgccctc tctcctactt
     1381 tggctgactc ttcaagaatg ccattcaaca agtatttatg gagtacctac tataatacag
     1441 tagctaacat gtattgagca cagatttttt ttggtaaaac tgtgaagagc taggatatat
     1501 acttggtgaa acaaaccagt atgttccctg ttctcttgag cttcgactct tctgtgcgct
     1561 actgctgcgc actgcttttt ctacaggcat tacatcaact cctaaggggt cctctgggat
     1621 tagttatgca gatattaaat cacccgaaga cactaactta cagaagacac aactccttcc
     1681 ccagtgatca ctgtcataac cagtgctcta ccgtatccca tcactgagga ctgatgttga
     1741 ctgacatcat tttctttatc gtaataaaca tgtggctcta ttagctgcaa gctttaccaa
     1801 gtaattggca tgacatctga gcacagaaat taaggcaaaa aaccaaagca aaacaaatac
     1861 atggtgctga aattaacttg atgccaagcc caaggcagct gatttctgtg tatttgaact
     1921 tagggcaaat cagagtctac acagacgcct acagaaagtt tcaggaagag gcaagatgca
     1981 ttcaatttga aagatattta tgggcaacaa agtaaggtca ggattagact tcaggcattc
     2041 ataaggcagg cactatcaga aagtgtacgc caactaaggg acccacaaag caggcagagg
     2101 taatgcagaa atctgttttg ttcccatgaa atcaccaatc aaggcctccg ttcttctaaa
     2161 gattagtcca tcatcattag caactgagat caaagcactc ttccacttta cgtgattaaa
     2221 atcaaacctg tatcagcaag ttaaatggtt ccatttctgt gatttttcta ttatttgagg
     2281 ggagttggca gaagttccat gtatatggga tctttacagg tcagatcttg ttacaggaaa
     2341 tttcaaaggt ttgggagtgg ggagggaaaa aagctcagtc agtgaggatc attttatcac
     2401 attagactgg ggcagaactc tgccaggatt taggaatatt ttcagaacag attttagata
     2461 ttatttctat ccatatattg aaaagaatac cattgtcaat cttatttttt taaaagtact
     2521 cagtgtagaa atcgctagcc cttaattctt ttccagcttt tcatattaat gtatgcagag
     2581 tctcaccaag ctcaaagaca ctggttgggg gtggagggtg ccacagggaa agctgtagaa
     2641 ggcaagaaga ctcgagaatc ccccagagtt atttttctcc ataaagacca tcagagtgct
     2701 taactgagct gttggagact gtgaggcatt taggaaaaaa atagcccact cacatcattc
     2761 cttgtaagtc ttaagttcat tttcatttta cgtggaggaa aaaaatttaa aaagctatta
     2821 gtatttatta atgaatttta ctgagacatt tcttagaaat atgcacttct atactagcaa
     2881 gctctgtctc taaaatgcaa gttggccttt tgcttgccac atttctgcat taaacttcta
     2941 tattagcttc aaaggctttt aaactcaatg cgaacattct acgggatgtt cttagatgcc
     3001 tttaaaaagg gggcagatct aattttattt gaaccctcac tttccaactt caccatgacc
     3061 cagtactaga gattagggca cttcaaagca ttgaaaaaaa tctactgata cttactttct
     3121 tagacaagta gttcttagtt aaccaccaat ggaactgggt tcattctgaa tcctggagga
     3181 gcttcctcgt gccacccagt gtttctgggc cctctgtgtg agcagccagg tgtgagctgt
     3241 tttagaagca gcgtgttgcc ttcatctctc ccgtttccca aaagaacaaa ggataaaggt
     3301 gacagtcaca ctcctgggtt aaaaaaagca ttccagaacc acttctcttt atgggcacaa
     3361 caaagaaacg aaggctgaag ttcgcctacc caaaatgaaa agtaggcttt acagtcaaaa
     3421 gtacttctgt tgattgctaa ataacttcat tttcttgaaa tagagcaact ttgagtgaaa
     3481 tctgcaacat ggataccatg tatgtaagat actgctgtac agaagagtta aggcttacag
     3541 tgcaaatgag gcgtcagctt tgggtgctaa aattaacaag tctaatatta ttaccatcaa
     3601 tcaggaagag aataataaat gtttaaacaa acacagcagt ctgtataaaa ataccgtgta
     3661 tcatttactc tttctgcagc tctatacgat aggcaggaga ggcttatgtg gcagcacaag
     3721 ccaggtgggg attttgtaaa gaagtgataa aacatttgta agtaatccaa gtaggtgtat
     3781 taaggcacca aaagtaacat ggcacccaac acccaaaaat aaaaatatga aatatgagtg
     3841 tgaactctga gtagagtatg aaacaccaca gaaagtctta gaaatagctc tggagtggct
     3901 ctcccaggac agtttccagt tgctgaatag tcttttggca ctgatgttct acttcttcac
     3961 attcatctaa aaaaaaaaaa aaaaaatcaa aattaaaatc tgagtcagtc cgcctgcctc
     4021 ggttctcatt agtttaattc ttaatgcctt gcactttccg gcaatcattc aatcaaaaga
     4081 gtgaaatgaa gcacattaac aaagcaggag gcgccacgga ccgcctccct ccacaccgct
     4141 ccttccgcct tcattccttg cccacaggct tgcactggaa gctgaataag aatccccaaa
     4201 actcaaactt cctagggatg ccaccccttt agtagctcac acctcccccc tccaagagct
     4261 aagaaacaaa ggagaatgta cttttgtagc ttagataagc aatgaatcag taaaggactg
     4321 atctacttgc tccaccaccc ctcccttaat aataacattt actgttattt cctgggccta
     4381 agactctatg ttccagaact gtcacagctc cccatgtcac actcactagc ttgtgatctt
     4441 tgtcaaataa ctgaaatctt ttaagcctct agtttcttcc tttgtaaaac agagataaaa
     4501 tgttgtggtt tttaagtgag ataatccaag taaagcacct aacatggagt agtgaatgaa
     4561 catcggttgc tactaaaagt ggacatccta ctgcatcctt aatgccacta ggcatttcca
     4621 tacaatctgg ggaccaaaac ttcaatcata taaatgtatg aggttaatta aaaacactac
     4681 tgtaatctgc ttgtatgatc acaaaccacc acaaaagaaa agatcgtgaa gattacactg
     4741 taaacggact ctcaaatgat caggaggtgg tcacttcgca acttgctccc tccacccaac
     4801 tcaaaacagg agctcgagcc tgcctgtatt tgagactgga gctgcctgta tgaggactgg
     4861 atcaactgct agtcacgtta tatccaaatc tgcattatca ttgggcacat tttcacagaa
     4921 ttttactgaa ttattcctta attgtttaat ggttgggaat agtttgggaa ttaccttcca
     4981 tcaactctgc taagaaagga atggattctg gtagcaagac aatataattc tcctttagtt
     5041 tttcagccag tgctaacaca gtaatcaaag cagcaaatcg aacctgaaag ggataaaaga
     5101 gcaaagaaat aaaaagtagt gttactgtat ttattatctt aagagctgta ctgacttgag
     5161 acaagctcta actttttaaa cattagttca catgcgttta ttcacttcat tatgttcatt
     5221 aagctttcat cttagaatac cagtttcacc atttgggagc tgtttgtaat atgtgcaacc
     5281 ttataaatag tgttttccaa actgtgtccc aggactgcaa atctttaatg tgaaatgtct
     5341 ttttataatc tcttccttta aaaaaaacca ataaaataaa atgccgcatg caaactcaag
     5401 tgtgtcacca gattttactt cattggcgct cgccagcccg ccaggctggc aataaagtgc
     5461 ctccagccac ctctggcagg tctcctcacc cacagcccct gactggtcac cactataatt
     5521 gtatgagggg ccaggacagt cgcttgggat aaactcccat ctcagcactg aataaaaaac
     5581 attctgtgtc acaatatcct agttttgggg ctttaaaaac gtctaggtgt tcctcacatg
     5641 ccttgtctat aataaggaaa gcaagcagta gttgggtatt gttagctttt gaaacaaaag
     5701 ccctactggt cttctaattt tggatatttt aattaaagaa tatctggaca gtacaaagtg
     5761 aattattaaa aaaccatttg taactaccta gattcaatca ggatttcctt gatttgtgca
     5821 aagtaaaata ttacaataaa tttgatactg ctacttgtat aaaaacctat ggtttaaaat
     5881 gtgggggttc atcataatag tctcattgtt agcatatcct aataaagaat ttgaactaat
     5941 aaatcctatt aataaaa
//
