LOCUS       XM_047437775            8521 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens low density lipoprotein receptor class A
            domain containing 4 (LDLRAD4), transcript variant X14, mRNA.
ACCESSION   XM_047437775
VERSION     XM_047437775.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000018.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8521
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
     gene            1..8521
                     /gene="LDLRAD4"
                     /gene_synonym="C18orf1"
                     /note="low density lipoprotein receptor class A domain
                     containing 4; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 5 ESTs, 690 long SRA
                     reads, 5 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 3 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:753"
                     /db_xref="HGNC:HGNC:1224"
                     /db_xref="MIM:606571"
     CDS             552..1424
                     /gene="LDLRAD4"
                     /gene_synonym="C18orf1"
                     /codon_start=1
                     /product="low-density lipoprotein receptor class A
                     domain-containing protein 4 isoform X2"
                     /protein_id="XP_047293731.1"
                     /db_xref="GeneID:753"
                     /db_xref="HGNC:HGNC:1224"
                     /db_xref="MIM:606571"
                     /translation="MLSQEPGGRERAKRGAAHRKRWREAAELNGGLSRECSVHGSIAV
                     TELEFAQIIIIVVVVTVMVVVIVCLLNHYKVSTRSFINRPNQSRRREDGLPQEGCLWP
                     SDSAAPRLGASEIMHAPRSRDRFTAPSFIQRDRFSRFQPTYPYVQHEIDLPPTISLSD
                     GEEPPPYQGPCTLQLRDPEQQMELNRESVRAPPNRTIFDSDLIDIAMYSGGPCPPSSN
                     SGISASTCSSNGRMEGPPPTYSEVMGHHPGASFLHHQRSNAHRGSRLQFQQNNAESTI
                     VPIKGKDRKPGNLV"
ORIGIN      
        1 gcgagcctgc gccgtcggct ggggccggag ggagaagctg ggcgccgagc gcgcgagcgg
       61 ttcaagctct acgttcgtga catcaaacct cctgttgggc catttccgag aactcccatc
      121 agtttctgta tagtgtaaaa gtttcagagg cggagcacag agagctgcgg ctgggacaag
      181 gagcacccgc gtgcaggtgc gaccctgcag gatgctggca gcggcgtggc caggggcgcc
      241 cgtgttctga gggcctgagg gccagcccct ccacccgcgc catggcctcc gcgccctggc
      301 tggacggctg acgggagcag ggaccgccgc cgcccaggtg ccacacccag gtaccgcccg
      361 cccgcgcgag agccgggcag gtgggccgcg gatgctccca gaggccggcc cagcagagcg
      421 atggacttgg acaggctaag atggaagtga cctgagcctc gcccggcggc ttcctcgacg
      481 ggacagcgca agagttggag cacaggcttg tccggggagc agtatgccgg aagctggttt
      541 tcaggccaca aatgctttca caggagccgg gaggaaggga gcgagccaag aggggtgctg
      601 cccaccggaa acgatggcgc gaggccgcag agctaaatgg gggcctctcc agggagtgct
      661 ctgttcacgg ctccatcgct gttacggagc tggagttcgc ccaaatcatc atcatcgtcg
      721 tggtggtcac ggtgatggtg gtggtcatcg tctgcctgct gaaccactac aaagtctcca
      781 cgcggtcctt catcaaccgc ccgaaccaga gccggaggcg ggaggacggg ctgccgcagg
      841 aagggtgcct gtggccttca gacagcgccg caccgcggct gggcgcctcg gagatcatgc
      901 atgccccgcg gtccagggac aggttcacag cgccgtcctt catccagagg gatcgcttca
      961 gccgcttcca gcccacctac ccctatgtgc agcacgagat tgatcttcct cccaccatct
     1021 ccctgtccga cggtgaagag ccacctcctt accaggggcc ctgcaccctg cagctccggg
     1081 accctgaaca gcagatggaa ctcaaccgag agtccgtgag ggccccaccc aaccgaacca
     1141 tatttgacag tgatttaata gacattgcta tgtatagcgg gggtccatgc ccacccagca
     1201 gcaactcggg catcagtgca agcacctgca gcagtaacgg gaggatggag gggccacccc
     1261 ccacatacag cgaggtgatg ggccaccacc caggcgcctc tttcctccat caccagcgca
     1321 gcaacgcaca caggggcagc agactgcagt ttcagcagaa caatgcagag agcacaatag
     1381 tacccatcaa aggcaaagat aggaagcctg ggaacctggt ctgattcctt ccaacgtgca
     1441 cttcagctgg agaaagaaac caagaaggga agcggccgct gggcccctcc tgcgcacagt
     1501 gttgttcagt ttcacatggt acaaataagt aaaaccaaat gagcaaacac ggtctttgtt
     1561 tctgattcct tttaggggaa ttgcatgcaa actagactga aatgatacaa acttccatct
     1621 ggtctgaccg caaacagtgt ttatttgggg acaggggttg ggatgggggt gtgggcaggg
     1681 gaaaacagag aacgggatgc tttgaagata ccatgaaata aaacccacag aggtatttga
     1741 tgtatttaat tgtgaaagga gactttgcag ataaatgagg ccagaatggc atgttttata
     1801 attaactgaa taaagaagga agcattatta tatattattg tggggaagaa ccagccagtt
     1861 cgctttttct cctaaggtgt ggaactttta ttttgtttta aaaatatgaa tcaaaattcc
     1921 tgtgttgtgt gccaaggtat aaagtggaga agttagatga gtgcaaggag ctcctttgtg
     1981 ttgtgatgat gtgttttaaa agttgcacta tcttaatgtt gaaaatattt acaagggaac
     2041 tgttttacgt gaagttctgt atgttgtctt ttcacctgtg gattgtaatc aggcccaagg
     2101 aatatcctgg agtggtcccc agaagcatcc aagaaaagat atttggggac gtagcctaac
     2161 attttaccaa cttacgtaaa tcaaaaaagt cattattgtt gcaggagttt gcatcaaata
     2221 gcagtgcatc gctgaagctt ttggagactt ttggatggaa gataagatag ggaagattaa
     2281 gttccagcat ttctgacttg ttattttgag ttactctgct actcttaggc tgcatagttt
     2341 atgagaaaat gaacacatgc atttatggat ccagtatcat gcagtgctgc cctcatcctc
     2401 cagcagtgca atttcttcag taatttagat ttttttcact atagcatgaa atatattcaa
     2461 atacatacct tattttatgc aataaattgt ttaaaatgca aggtggttat tctgcatact
     2521 gttgaaatat gtgactcctc agtatattcc cattgcctct ccccctttcc tcgacagctt
     2581 agttcagttc tgcagggctg ctcagttcac aggaggctcc cagcagccac cccacatcca
     2641 gcctacacag aacttcgtgt gggagtggtg tgggtggtgg tttcttatgc tttggaagcc
     2701 cctagaaata atgacggaag aatgccatgt tgctgatcgt ggtaataagc cattgtgggt
     2761 tattgtatgt cactagtatt agcatagcat tcttaaagga atgcagtgct caaaacctac
     2821 ccaaattccc gcaggattct accaaaccct tccccaggcc agcttttgta ctgaaggcaa
     2881 gaactggaca gtcagagaac agtggagggg gcaagtgact gaagagcacc gggtaaaaag
     2941 cacaacatgc agttaaaatg caactagaaa actaatttta aatattgtta gttttaatat
     3001 tcctgatatt tacaaatatt cattcttata tacaatgaaa aaaataactt tcttctgcag
     3061 atgtaagcac tggcttttat aagagcagca gccaacacgt ttagcagaca ctgcgcgtgg
     3121 agaagggctt atctgcagta cactctgcca tgtggagggt gggcctctgt ggcctcttca
     3181 cataacaaga tgagctggaa tgatgattcc atgactccca cctatgcagc cttaaagcca
     3241 aatccgcgtg tgtgtgtttg tgtctgtctg tgggtctcga aggtgatccg tcggtgcggt
     3301 ggctctgtgc tgtaactgga gagactgttc caaaccccaa gagttgtctg atcctagtct
     3361 gttcccttct gcttcttacc tctgtagata ggtcactggt ttttgtttgt ttgttttgag
     3421 gattggaatt tccattacat tcatcctttg cacacagtaa catccacaga actagtccaa
     3481 ctcttaaaag gagagaggaa aaacacaggc accagttgtc agctcatgct tacaacctgt
     3541 gtggaagtat atacagttga gagtcacagt ggaggttctg agactggatt cagtcttgtt
     3601 ccagtgacag ttggaaggcc tctgctggag agacaccagc tctcagggca gagattggct
     3661 tggggccaga aggaccctcc ccaaccctgg agacaccctg aaggttcact ggctctccag
     3721 attagcctct cttcctctgt caggcaaaga tgaggagccc gtgttcccat cgggccctgc
     3781 tggcagggac ttgcagtgga ttcttggtca ggtgtgccca cagatgcgga ggcgaggtga
     3841 gtgattccat catttcagtt ctcacctgca gttttggtga agcaggagat gcaccccaca
     3901 gctctagctc tcaaatggct tcacagtcct tacttctcta cctgcctcaa gaaggggctc
     3961 agagcagaga cttgtgaatt ccttagtaac tgtgagtata tgaatgtgtt gcacatgtcc
     4021 acagtattgg cgagataatt acataattca gataccttta atcatctttc aagaaagagg
     4081 ctcctcccat tcaaccaccc tagagaactg cctttgttaa atagttattt aaagactcat
     4141 acatatcaaa ccatgacttt gaaaggtctt cgaggctggg gctctgtaat gaattagttt
     4201 aaaagccaag gtcataacat gaattgatgg tcaatttccc ttcagcagaa ggaaaaggtg
     4261 atttagatca gtagctcttt tgaaggttgt ggctgacctg ttcataccgt gtcgcctcat
     4321 ggctagtgtg gcgttgaaag agtagcgact gggaagatac aacttacaca gtggggccta
     4381 ttgttctttc aagaaccctt tttttagctt atagaaccca tgggtccagt ttagtaacga
     4441 gtgatttagg caatcaatga taggtttata atcttagatt attccagcaa agtgtggatt
     4501 gcattgttag gaagaacatt tggtgggaat gaacactcct gggcataccg ctgacttttg
     4561 tcccttgttc ccggtgtagg agacccaagg catcttgaat cccatctata agaacacaat
     4621 cttccagcat acgtttgctt tttcagaaac tctagcattc tctttaaata ctgacgcaat
     4681 ccttaatgga aaagagattt catgaagcaa attatgtatt tcaatagttc ttctattttt
     4741 agtgtccaaa atttactaat acagaagctt gacaagcatg tcctcaccct ccccaccaca
     4801 taaacacatg gacacacacc caagccacaa gaaatcccaa gagagcagaa gcgaattttt
     4861 aaaagattta tcgtgaggac tgcatttcca ttcactaatt ttggctcaaa cttatgaggc
     4921 aggaaatagg ggccaacagt aaatggggga ggcctcctga caccagcaga ggaattttgt
     4981 acccaggcga ggacttcttg aacttctgcg tatctccgtt tgatctcttt cacctttatt
     5041 tcatcttcat aagaatgaga aaggctcaaa aggaagcact tttagaaatc ttctctgacc
     5101 tagaagaatc catccaaatc cctgccttcc tctctgaacc aacagttccc ttctctgaca
     5161 ggggccatcc tctatcttcc atccagcggc tcttcttttt aggaaggctc tggtgcagag
     5221 cacttcaaat atgtcctcag gccagatact gattgctagt agagagacac ccggcaccca
     5281 gtccgaagcc ctccctcaaa ggaccggctc atggcgttgg tcactggcag gctcagagac
     5341 attctgctgt gggcgcaggg agcccggccc cccatgcagc catgactgga tgcgccccca
     5401 tctcgggggc ttgctgcact gcttgtttat tgaattttgc tacttagaat ggcaacatta
     5461 actttgtgta ccattcattt tttaaaaatt ttccaaagct cggcagtgta tgaaagaaaa
     5521 aactgggaaa gatacttggt ttctgttaac ttttgtgttg cttgcttaag tgattaaagc
     5581 cagtgcttgg agccaagcct tcatgccacg aacatgctcc acagcctgcc ctttgctctc
     5641 ctgctcacac tgaccaagaa tgccgcgtgc ttggcctact gaggtgaaag gacaattgaa
     5701 tgacaggtgg gcaaagggag aacttcccct tcttggtgcg aggaaagtca caaatttaaa
     5761 aatgttgctt ccagcccaga tcctaaatgc tagttctcag cagctgcgtg gcttaccgtt
     5821 cgccatttcc accaccgcca gctgccagca ccgctacaga tcacagagat gtgaacagac
     5881 aatggaaagc actcttagcc ttgcagtggt ctacattttt taggaaccaa tatttcagca
     5941 ttctttatta cccggcacgc tgtgtccttt gcagagttca agtttatgtt actgccaggg
     6001 tcagacagtc atttgctgct gctgctgctg ctgctgcttc tcgaactgga tgcattagga
     6061 agctgctgtc tgagtgtagg aatgtcttgc taagaaagca atgtcttcct tcatcctttt
     6121 ctttcttccc tctgcgtgtc cttgtttttg tgtaatgcgg gagagggtta gagctataga
     6181 gattatatat acactatccg tgcacattat atatatgtag atatacccct atcatgtcag
     6241 agatctgcat gtcagttttt cagcaactaa ggtgcctcat gttctgagtt cagcagatat
     6301 aggaaccaag ccgccccctc ctgcacttga tgctcccacc tttgttgtgc ctcacttaaa
     6361 atggtgcttt tttcagttgt ctgtcttttc ttatgttttt atttgtaagg tgctgtatat
     6421 aagttgaata tattatgcac atatcctacc caatgggtag aacaaaaagt tgttaatact
     6481 gtaatataat gtatagatga taccaatttt aacagaaatg gcatagaatt tgtgaatgcc
     6541 tatgtgcttt gtcctctttt gtaaggaaat ttgcaaatgg atgcatacag attaaagtct
     6601 atgtagttta ttttcctatt aaatatcaat attataacac aagagaaaga agtgtgaaca
     6661 aacaagcaac agtttatgac cagcgtatat atagcaatgg aaagttgcat ctttgctgtg
     6721 aaaacacttt aaagaaaata ctttttaaaa aatcccacag ctttttggtt gccactagac
     6781 gcttcttatt ttaatcattt tagtaatgct cagctggacc agtgttagtt atatttgagt
     6841 cagaaaaatg ttgtttttca acttgcttta taatctcctg catctatctc ctgctgtagc
     6901 atcacgaagg tgtcaggcaa cagtgaaaag tgcacatttt tgttgttgca gaaactgtgt
     6961 cagaggaata agtaaatcag cctgcagcag aagactttgt tcagctccag aggcatctgt
     7021 gaccgtctgt gtccaagtct ctctgtgcct ttttctttta caaactgaag ctgtggagcc
     7081 aatgaagtaa cagtagagat tgtagggaaa gaatacctca ggaaaaacaa atacacttac
     7141 aagaagaccc tgttcttaga aaatgtgttt agttatgggt tagcactaga agagacttgg
     7201 ctgtcagcca gccaagtgaa ggacctctca tccattccca ttcatgtccc atcataatac
     7261 ggacccaaaa agcaaactcg gttttgccat cagttagaaa ttacgttttg gattgtatat
     7321 tgttacatct ctcttccggc ttagttttta gtgtctgatt gtgacctctg catttatctt
     7381 caaataccct aattttaaaa caaaagaaca agaaaagttt ataacaccat gttcactaaa
     7441 accacggttg aatcttgggt gtgggcatcc tttcgagtgt tgtccataag agcagttcgt
     7501 ggaattttgc ccatctgacc catattatca gcttattctg ccaccagagt agagtctaat
     7561 aaattccaaa gtttttattt gctccatggt gtatgttctg actttgaaaa tgtcagattc
     7621 tataatcata cccctaacat ccaggaaaca aatgacagat tatctttaaa ctgaaattga
     7681 ctctacaatg caacccttaa tgctgaatgg attaaaaaag tcagcccttt tagtatctgt
     7741 ttgaaagggc cgtaaaaagt tgacactttt gttgttgtgg atcctgcgtg tctagaccca
     7801 cgtgttgttt ccatcgtata ctgtagggtg caccccttgg gattcatcat taagaactga
     7861 ggctcactgt tgtcagaaac aaagctccca ccccccaggt tcaaccttgt gggagaactg
     7921 ttgagcatga gaatgttcta gactcagagg tactaaaatt tgttaccaca tcattgcttc
     7981 ctttctacag gacgaattga ggcttaaact ttactgttaa tgatactggt tcattttaat
     8041 gtgcttgttg gtatgttgct atttttcatt tcatagcttt caaaaatcat gctaattgta
     8101 tacttgtcta gtttaaggct attttaaaat atgtacaata ctattcacag catttagttc
     8161 gtttaatttt tattataaag caatctacta aaaaagtaca actgtatttg aacttttcaa
     8221 tagttgtttg tgagctatga taatcaaaag tcattaaagt cttttttaac aaacattcgt
     8281 gcttactttt caacataatt cccagttata tacagaaaaa gatttccacc tgtcacgtat
     8341 ctgcctcttt tacctgagca atggtgtagt tcttagacct aaggtctgta attgcaatac
     8401 ttttaaagaa agatgttgct ctaagtgctg tttgttagtt atgaaatcag atttttctgc
     8461 ttgttcttaa tgctgtggtc aaaccatagc acaaaatcat taaaaataat cagcggcata
     8521 c
//
