LOCUS       NM_001395990             612 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens late cornified envelope 7A (LCE7A), mRNA.
ACCESSION   NM_001395990
VERSION     NM_001395990.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 612)
  AUTHORS   Holthaus,K.B., Lachner,J., Ebner,B., Tschachler,E. and Eckhart,L.
  TITLE     Gene duplications and gene loss in the epidermal differentiation
            complex during the evolutionary land-to-water transition of
            cetaceans
  JOURNAL   Sci Rep 11 (1), 12334 (2021)
   PUBMED   34112911
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL162596.30.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000650277.2/ ENSP00000497579.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                AL162596.30        50386-50421
            37-612              AL162596.30        51067-51642
FEATURES             Location/Qualifiers
     source          1..612
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.3"
     gene            1..612
                     /gene="LCE7A"
                     /note="late cornified envelope 7A"
                     /db_xref="GeneID:122526777"
                     /db_xref="HGNC:HGNC:55921"
     exon            1..36
                     /gene="LCE7A"
                     /inference="alignment:Splign:2.1.0"
     exon            37..612
                     /gene="LCE7A"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..345
                     /gene="LCE7A"
                     /note="late cornified envelope 7A protein"
                     /codon_start=1
                     /product="late cornified envelope protein 7A"
                     /protein_id="NP_001382919.1"
                     /db_xref="CCDS:CCDS91055.1"
                     /db_xref="GeneID:122526777"
                     /db_xref="HGNC:HGNC:55921"
                     /translation="MSYQKHQQKWQLPAKCLPKYPSKWTPQAPASCPAPCPPPAPSCC
                     VSSCCISGFGGHCSLVSLRFPRFYLRQPQHSDCCEHESSRCSTCYSSGDCS"
     regulatory      585..590
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LCE7A"
                     /note="hexamer: AATAAA"
     polyA_site      612
                     /gene="LCE7A"
                     /note="major polyA site"
ORIGIN      
        1 gtagtcccat cgtttgccca gggttaagag gacaagagta actggacttt ctccaagatg
       61 tcctatcaga aacaccagca gaaatggcag ctccctgcca agtgcctccc caaatatcca
      121 tccaagtgga cccctcaggc tcctgcttca tgtccagctc catgcccccc tccagctccc
      181 tcctgctgtg tttccagttg ctgtatttct ggctttggag gccactgctc tctagtttca
      241 ctccggtttc cacgattcta cctgcgtcag ccccagcatt ctgactgctg tgagcacgag
      301 tcttctagat gttccacttg ctatagctct ggagactgca gctgacctgt gacctttgag
      361 gaaccaaaga accacagcca aggacccgcc ctgagttgat gtcttccctc actcttaccc
      421 tcctccttcc ttctcctcct gaactcagct gcctagctcc ataggtgatg ggctccccct
      481 tttgctgaga acctcaggcc tcttggcctt ggctgtgttc ctagatcaag gagacctgca
      541 tgcaaaagaa aaacctgctt tttgaagcct gatctgtgtg ctaaaataaa gcttatcttt
      601 cctggtgccc ta
//
