LOCUS       NM_001128600             640 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens late cornified envelope 6A (LCE6A), mRNA.
ACCESSION   NM_001128600 XM_001721565 XM_001724452 XM_001724477
VERSION     NM_001128600.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Jackson,B., Tilli,C.M., Hardman,M.J., Avilion,A.A., MacLeod,M.C.,
            Ashcroft,G.S. and Byrne,C.
  TITLE     Late cornified envelope family in differentiating
            epithelia--response to calcium and ultraviolet irradiation
  JOURNAL   J Invest Dermatol 124 (5), 1062-1070 (2005)
   PUBMED   15854049
  REMARK    GeneRIF: Describes neighboring LCE family members that are present
            in the same cluster on chromosome 1q21.
REFERENCE   2  (bases 1 to 640)
  AUTHORS   Harrington,J.J., Sherf,B., Rundlett,S., Jackson,P.D., Perry,R.,
            Cain,S., Leventhal,C., Thornton,M., Ramachandran,R.,
            Whittington,J., Lerner,L., Costanzo,D., McElligott,K., Boozer,S.,
            Mays,R., Smith,E., Veloso,N., Klika,A., Hess,J., Cothren,K., Lo,K.,
            Offenbacher,J., Danzig,J. and Ducar,M.
  TITLE     Creation of genome-wide protein expression libraries using random
            activation of gene expression
  JOURNAL   Nat Biotechnol 19 (5), 440-445 (2001)
   PUBMED   11329013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DQ991251.1 and BG210316.1.
            
            On May 17, 2019 this sequence version replaced NM_001128600.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ991251.1, AA046394.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000431011.3/ ENSP00000411070.2
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-639               DQ991251.1         3-641
            640-640             BG210316.1         489-489
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.3"
     gene            1..640
                     /gene="LCE6A"
                     /gene_synonym="C1orf44"
                     /note="late cornified envelope 6A"
                     /db_xref="GeneID:448835"
                     /db_xref="HGNC:HGNC:31824"
     exon            1..156
                     /gene="LCE6A"
                     /gene_synonym="C1orf44"
                     /inference="alignment:Splign:2.1.0"
     exon            157..640
                     /gene="LCE6A"
                     /gene_synonym="C1orf44"
                     /inference="alignment:Splign:2.1.0"
     CDS             178..420
                     /gene="LCE6A"
                     /gene_synonym="C1orf44"
                     /codon_start=1
                     /product="late cornified envelope protein 6A"
                     /protein_id="NP_001122072.1"
                     /db_xref="CCDS:CCDS44227.1"
                     /db_xref="GeneID:448835"
                     /db_xref="HGNC:HGNC:31824"
                     /translation="MSQQKQQSWKPPNVPKCSPPQRSNPCLAPYSTPCGAPHSEGCHS
                     SSQRPEVQKPRRARQKLRCLSRGTTYHCKEEECEGD"
ORIGIN      
        1 acaaggcctc cagactcctc ctgggataac ttgtccacac atcttccact agggtaaggc
       61 tacttctggc tgaggagaca cttggatgta gctcaagtgc tgcttaggca gtcctgatct
      121 ctcctctcgt ctcttcccag ggagctgaaa agccagattc gacctggtag ccaagcaatg
      181 tcacagcaga agcagcaatc ttggaagcct ccaaatgttc ccaaatgctc ccctccccaa
      241 agatcaaacc cctgcctagc tccctactcg actccttgtg gtgctcccca ttcagaaggt
      301 tgtcattcca gttcccaaag gcctgaggtt cagaagccta ggagggctcg tcaaaagctg
      361 cgctgcctaa gtaggggcac aacctaccac tgcaaagagg aagagtgtga aggcgactga
      421 gcccagaaga gttgaggcac aggtgcagtt actctctccc tgccccacct ttgggtacta
      481 attccccctt ggaaagccag gccctcaacc tctcatttgg actgagaaac acttcctgat
      541 ccccagctct agagaagcga gaactaggct gagccacgct gctactgctc tcttccattc
      601 accccttcag ctcagcaaca ataaagctgc tttacttgga
//
