LOCUS       NM_178352                460 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens late cornified envelope 1D (LCE1D), mRNA.
ACCESSION   NM_178352
VERSION     NM_178352.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 460)
  AUTHORS   Yachie,N., Petsalaki,E., Mellor,J.C., Weile,J., Jacob,Y., Verby,M.,
            Ozturk,S.B., Li,S., Cote,A.G., Mosca,R., Knapp,J.J., Ko,M., Yu,A.,
            Gebbia,M., Sahni,N., Yi,S., Tyagi,T., Sheykhkarimli,D., Roth,J.F.,
            Wong,C., Musa,L., Snider,J., Liu,Y.C., Yu,H., Braun,P.,
            Stagljar,I., Hao,T., Calderwood,M.A., Pelletier,L., Aloy,P.,
            Hill,D.E., Vidal,M. and Roth,F.P.
  TITLE     Pooled-matrix protein interaction screens using Barcode Fusion
            Genetics
  JOURNAL   Mol Syst Biol 12 (4), 863 (2016)
   PUBMED   27107012
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 460)
  AUTHORS   Swaminathan,S., Huentelman,M.J., Corneveaux,J.J., Myers,A.J.,
            Faber,K.M., Foroud,T., Mayeux,R., Shen,L., Kim,S., Turk,M.,
            Hardy,J., Reiman,E.M. and Saykin,A.J.
  CONSRTM   Alzheimer's Disease Neuroimaging Initiative  and  NIA-LOAD/NCRAD
            Family Study Group
  TITLE     Analysis of copy number variation in Alzheimer's disease in a
            cohort of clinically characterized and neuropathologically verified
            individuals
  JOURNAL   PLoS One 7 (12), e50640 (2012)
   PUBMED   23227193
REFERENCE   4  (bases 1 to 460)
  AUTHORS   Jackson,B., Tilli,C.M., Hardman,M.J., Avilion,A.A., MacLeod,M.C.,
            Ashcroft,G.S. and Byrne,C.
  TITLE     Late cornified envelope family in differentiating
            epithelia--response to calcium and ultraviolet irradiation
  JOURNAL   J Invest Dermatol 124 (5), 1062-1070 (2005)
   PUBMED   15854049
  REMARK    GeneRIF: paper describing nomenclature changes and expression in
            range of tissues and in response to UV
REFERENCE   5  (bases 1 to 460)
  AUTHORS   Marshall,D., Hardman,M.J., Nield,K.M. and Byrne,C.
  TITLE     Differentially expressed late constituents of the epidermal
            cornified envelope
  JOURNAL   Proc Natl Acad Sci U S A 98 (23), 13031-13036 (2001)
   PUBMED   11698679
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL353779.11 and BG697954.1.
            
            On May 17, 2019 this sequence version replaced NM_178352.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BG697954.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000326233.7/ ENSP00000316737.6
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                AL353779.11        81124-81153
            31-460              BG697954.1         1-430
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.3"
     gene            1..460
                     /gene="LCE1D"
                     /gene_synonym="LEP4"
                     /note="late cornified envelope 1D"
                     /db_xref="GeneID:353134"
                     /db_xref="HGNC:HGNC:29465"
                     /db_xref="MIM:612606"
     exon            1..51
                     /gene="LCE1D"
                     /gene_synonym="LEP4"
                     /inference="alignment:Splign:2.1.0"
     exon            52..460
                     /gene="LCE1D"
                     /gene_synonym="LEP4"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..418
                     /gene="LCE1D"
                     /gene_synonym="LEP4"
                     /note="late envelope protein 4"
                     /codon_start=1
                     /product="late cornified envelope protein 1D"
                     /protein_id="NP_848129.1"
                     /db_xref="CCDS:CCDS1025.1"
                     /db_xref="GeneID:353134"
                     /db_xref="HGNC:HGNC:29465"
                     /db_xref="MIM:612606"
                     /translation="MSCQQSQQQCQPPPKCTPKCTPKCPAPKCPPKCPPVSSCCSVSS
                     GGCCGSSSGGGCGSNSGGCCSSGGGGCCLSHHRRHRSHRRRPQSSDCCSQPSGGSSCC
                     GGGSSQHSGGCC"
ORIGIN      
        1 atccactcac ctcctgaggt gctaaagaac cctgtgctgc ctgtgactcc gctcctgaac
       61 acccaccacc gagatgtcct gccagcagag ccagcagcag tgccagcccc ctcccaagtg
      121 cactcccaag tgcactccca agtgccccgc ccctaaatgt ccccctaagt gccctccagt
      181 ctcttcctgc tgcagtgtca gctccggagg ctgctgtggc tccagctctg ggggcggctg
      241 tggctccaac tctgggggct gctgcagctc tgggggtggt ggctgctgcc tgagccacca
      301 caggcgccac aggtcccacc gtcgcagacc ccagagctct gactgctgca gccagccctc
      361 ggggggctcc agctgctgcg gtgggggcag cagccagcac tctggaggct gctgctgaag
      421 tggaccttga cttcctcttc cttctgattc tgcctgaata
//
