LOCUS       XM_047419519            3484 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens large tumor suppressor kinase 1 (LATS1),
            transcript variant X7, mRNA.
ACCESSION   XM_047419519
VERSION     XM_047419519.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3484
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..3484
                     /gene="LATS1"
                     /gene_synonym="WARTS; wts"
                     /note="large tumor suppressor kinase 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 8 ESTs, 711 long SRA reads, 1 Protein, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments"
                     /db_xref="GeneID:9113"
                     /db_xref="HGNC:HGNC:6514"
                     /db_xref="MIM:603473"
     CDS             394..3384
                     /gene="LATS1"
                     /gene_synonym="WARTS; wts"
                     /codon_start=1
                     /product="serine/threonine-protein kinase LATS1 isoform
                     X5"
                     /protein_id="XP_047275475.1"
                     /db_xref="GeneID:9113"
                     /db_xref="HGNC:HGNC:6514"
                     /db_xref="MIM:603473"
                     /translation="MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKP
                     SDAAKAEHNMSKMSTEDPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVN
                     PQMLQDLQAAGFDEDMVIQALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPIN
                     ASMKPGNVQQSVNRKQSWKGSKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGS
                     GISAFVQAHPSNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKR
                     YSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQS
                     SSKFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNRQPPPPYPLTAANGQSPSALQTG
                     GSAAPSSYTNGSIPQSMMVPNRNSHNMELYNISVPGLQTNWPQSSSAPAQSSPSSGHE
                     IPTWQPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAITPAPIQQPVKSMRVLKPEL
                     QTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAPNYQGPPPPYPKHLLHQ
                     NPSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDE
                     ERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMR
                     KMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKD
                     VLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMG
                     IFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWT
                     HDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTP
                     NYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKPGMVAHTCNPS
                     ALEGHSRKNTGTQEFEIGLGNIFF"
ORIGIN      
        1 agcggagtgc ggcggcggcg acactgagtg gaaggcaaaa tggcggcggc ggcggcggtg
       61 gcctggtgtt aaggggagag ccaggtcctc acgacccctg ggacgggccg cgctggcccg
      121 cggcagcccc cccgttcgtc tccccgctct gccccaccag ggatacttgg ggttgctggg
      181 acggactctg gccgcctcag cgtccgccct caggcccgtg gccgctgtcc aggagctctg
      241 ctctcccctc cagagttaat tatttatatt gtaaagaatt ttaacagtcc tggggacttc
      301 cttgaaggat cattttcact tttgctcaga agaaagctct ggatctatca aataaagaag
      361 tccttcgtgt gggctacata tatagatgtt ttcatgaaga ggagtgaaaa gccagaagga
      421 tatagacaaa tgaggcctaa gacctttcct gccagtaact atactgtcag tagccggcaa
      481 atgttacaag aaattcggga atcccttagg aatttatcta aaccatctga tgctgctaag
      541 gctgagcata acatgagtaa aatgtcaacc gaagatcctc gacaagtcag aaatccaccc
      601 aaatttggga cgcatcataa agccttgcag gaaattcgaa actctctgct tccatttgca
      661 aatgaaacaa attcttctcg gagtacttca gaagttaatc cacaaatgct tcaagacttg
      721 caagctgctg gatttgatga ggatatggtt atacaagctc ttcagaaaac taacaacaga
      781 agtatagaag cagcaattga attcattagt aaaatgagtt accaagatcc tcgacgagag
      841 cagatggctg cagcagctgc cagacctatt aatgccagca tgaaaccagg gaatgtgcag
      901 caatcagtta accgcaaaca gagctggaaa ggttctaaag aatccttagt tcctcagagg
      961 catggcccgc cactaggaga aagtgtggcc tatcattctg agagtcccaa ctcacagaca
     1021 gatgtaggaa gacctttgtc tggatctggt atatcagcat ttgttcaagc tcaccctagc
     1081 aacggacaga gagtgaaccc cccaccacca cctcaagtaa ggagtgttac tcctccacca
     1141 cctccaagag gccagactcc ccctccaaga ggtacaactc cacctccccc ttcatgggaa
     1201 ccaaactctc aaacaaagcg ctattctgga aacatggaat acgtaatctc ccgaatctct
     1261 cctgtcccac ctggggcatg gcaagagggc tatcctccac cacctctcaa cacttccccc
     1321 atgaatcctc ctaatcaagg acagagaggc attagttctg ttcctgttgg cagacaacca
     1381 atcatcatgc agagttctag caaatttaac tttccatcag ggagacctgg aatgcagaat
     1441 ggtactggac aaactgattt catgatacac caaaatgttg tccctgctgg cactgtgaat
     1501 cggcagccac cacctccata tcctctgaca gcagctaatg gacaaagccc ttctgcttta
     1561 caaacagggg gatctgctgc tccttcgtca tatacaaatg gaagtattcc tcagtctatg
     1621 atggtgccaa acagaaatag tcataacatg gaactatata acattagtgt acctggactg
     1681 caaacaaatt ggcctcagtc atcttctgct ccagcccagt catccccgag cagtgggcat
     1741 gaaatcccta catggcaacc taacatacca gtgaggtcaa attcttttaa taacccatta
     1801 ggaaatagag caagtcactc tgctaattct cagccttctg ctacaacagt cactgcaatt
     1861 acaccagctc ctattcaaca gcctgtgaaa agtatgcgtg tattaaaacc agagctacag
     1921 actgctttag cacctacaca cccttcttgg ataccacagc caattcaaac tgttcaaccc
     1981 agtccttttc ctgagggaac cgcttcaaat gtgactgtga tgccacctgt tgctgaagct
     2041 ccaaactatc aaggaccacc accaccctac ccaaaacatc tgctgcacca aaacccatct
     2101 gttcctccat acgagtcaat cagtaagcct agcaaagagg atcagccaag cttgcccaag
     2161 gaagatgaga gtgaaaagag ttatgaaaat gttgatagtg gggataaaga aaagaaacag
     2221 attacaactt cacctattac tgttaggaaa aacaagaaag atgaagagcg aagggaatct
     2281 cgtattcaaa gttattctcc tcaagcattt aaattcttta tggagcaaca tgtagaaaat
     2341 gtactcaaat ctcatcagca gcgtctacat cgtaaaaaac aattagagaa tgaaatgatg
     2401 cgggttggat tatctcaaga tgcccaggat caaatgagaa agatgctttg ccaaaaagaa
     2461 tctaattaca tccgtcttaa aagggctaaa atggacaagt ctatgtttgt gaagataaag
     2521 acactaggaa taggagcatt tggtgaagtc tgtctagcaa gaaaagtaga tactaaggct
     2581 ttgtatgcaa caaaaactct tcgaaagaaa gatgttcttc ttcgaaatca agtcgctcat
     2641 gttaaggctg agagagatat cctggctgaa gctgacaatg aatgggtagt tcgtctatat
     2701 tattcattcc aagataagga caatttatac tttgtaatgg actacattcc tgggggtgat
     2761 atgatgagcc tattaattag aatgggcatc tttccagaaa gtctggcacg attctacata
     2821 gcagaactta cctgtgcagt tgaaagtgtt cataaaatgg gttttattca tagagatatt
     2881 aaacctgata atattttgat tgatcgtgat ggtcatatta aattgactga ctttggcctc
     2941 tgcactggct tcagatggac acacgattct aagtactatc agagtggtga ccatccacgg
     3001 caagatagca tggatttcag taatgaatgg ggggatccct caagctgtcg atgtggagac
     3061 agactgaagc cattagagcg gagagctgca cgccagcacc agcgatgtct agcacattct
     3121 ttggttggga ctcccaatta tattgcacct gaagtgttgc tacgaacagg atacacacag
     3181 ttgtgtgatt ggtggagtgt tggtgttatt ctttttgaaa tgttggtggg acaacctcct
     3241 ttcttggcac aaacaccatt agaaacacaa atgaagccag gtatggtggc tcacacctgt
     3301 aatcccagcg ctttggaagg ccacagcagg aagaacactg gaacccagga gtttgagatc
     3361 ggcttgggca acatattctt ttaaagaact caaggtgaca ggctgaatgc agtggcttat
     3421 gcctgcaatc ccagcacttt gggaggctga cgcaagagga ttgcttgaag tcaggagttc
     3481 aaga
//
