LOCUS       NM_052879               6441 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens La ribonucleoprotein 4 (LARP4), transcript variant 1,
            mRNA.
ACCESSION   NM_052879
VERSION     NM_052879.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6441)
  AUTHORS   Zhang,J., Yang,Y., Song,X., Xing,K. and Chen,Y.
  TITLE     Biological functions of Circular RNA_LARP4/ Upstream frameshift 1
            in development of gastric cancer
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 70 (4), 176-180 (2024)
   PUBMED   38678610
  REMARK    GeneRIF: Biological functions of Circular RNA_LARP4/ Upstream
            frameshift 1 in development of gastric cancer.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6441)
  AUTHORS   Lewis,B.M., Cho,C.Y., Her,H.L., Mizrahi,O., Hunter,T. and Yeo,G.W.
  TITLE     LARP4 is an RNA-binding protein that binds nuclear-encoded
            mitochondrial mRNAs to promote mitochondrial function
  JOURNAL   RNA 30 (3), 223-239 (2024)
   PUBMED   38164626
  REMARK    GeneRIF: LARP4 is an RNA-binding protein that binds nuclear-encoded
            mitochondrial mRNAs to promote mitochondrial function.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6441)
  AUTHORS   Lu,M., Gong,B., Wang,Y. and Li,J.
  TITLE     CircBNC2 affects epithelial ovarian cancer progression through the
            miR-223-3p/ LARP4 axis
  JOURNAL   Anticancer Drugs 34 (3), 384-394 (2023)
   PUBMED   36730544
  REMARK    GeneRIF: CircBNC2 affects epithelial ovarian cancer progression
            through the miR-223-3p/ LARP4 axis.
REFERENCE   4  (bases 1 to 6441)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   5  (bases 1 to 6441)
  AUTHORS   Mattijssen,S., Iben,J.R., Li,T., Coon,S.L. and Maraia,R.J.
  TITLE     Single molecule poly(A) tail-seq shows LARP4 opposes deadenylation
            throughout mRNA lifespan with most impact on short tails
  JOURNAL   Elife 9, e59186 (2020)
   PUBMED   32744499
  REMARK    GeneRIF: Single molecule poly(A) tail-seq shows LARP4 opposes
            deadenylation throughout mRNA lifespan with most impact on short
            tails.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6441)
  AUTHORS   Bai,S.W., Herrera-Abreu,M.T., Rohn,J.L., Racine,V., Tajadura,V.,
            Suryavanshi,N., Bechtel,S., Wiemann,S., Baum,B. and Ridley,A.J.
  TITLE     Identification and characterization of a set of conserved and new
            regulators of cytoskeletal organization, cell morphology and
            migration
  JOURNAL   BMC Biol 9, 54 (2011)
   PUBMED   21834987
  REMARK    Erratum:[BMC Biol. 2024 Oct 10;22(1):228. doi:
            10.1186/s12915-024-02036-3.. PMID: 39390519]
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6441)
  AUTHORS   Yang,R., Gaidamakov,S.A., Xie,J., Lee,J., Martino,L., Kozlov,G.,
            Crawford,A.K., Russo,A.N., Conte,M.R., Gehring,K. and Maraia,R.J.
  TITLE     La-related protein 4 binds poly(A), interacts with the
            poly(A)-binding protein MLLE domain via a variant PAM2w motif, and
            can promote mRNA stability
  JOURNAL   Mol Cell Biol 31 (3), 542-556 (2011)
   PUBMED   21098120
  REMARK    GeneRIF: LARP4 activity is integrated with other PAM2 protein
            activities by PABP as part of mRNA homeostasis.
REFERENCE   8  (bases 1 to 6441)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   9  (bases 1 to 6441)
  AUTHORS   Puigdecanet,E., Espinet,B., Villa,O., Florensa,L., Besses,C.,
            Serrano,S. and Sole,F.
  TITLE     Detection of abnormalities of PRV-1, TPO, and c-MPL genes detected
            by fluorescence in situ hybridization in essential thrombocythemia
  JOURNAL   Cancer Genet Cytogenet 167 (1), 39-42 (2006)
   PUBMED   16682284
  REMARK    GeneRIF: FISH study showed no cytogenetic abnormalities in any of
            the analyzed cases.
REFERENCE   10 (bases 1 to 6441)
  AUTHORS   Kralovics,R. and Skoda,R.C.
  TITLE     Molecular pathogenesis of Philadelphia chromosome negative
            myeloproliferative disorders
  JOURNAL   Blood Rev 19 (1), 1-13 (2005)
   PUBMED   15572213
  REMARK    GeneRIF: The c-MPL protein altered expression provide an
            opportunity to diagnose and identify subpopulations of MPD
            patients.
            Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC090058.21.
            
            On Nov 23, 2018 this sequence version replaced NM_052879.4.
            
            Transcript Variant: This variant (1) encodes isoform a.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR936626.1, SRR1660809.246435.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000398473.7/ ENSP00000381490.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               AC090058.21        63296-63439
            145-292             AC090058.21        90173-90320
            293-448             AC090058.21        91346-91501
            449-524             AC090058.21        92906-92981
            525-661             AC090058.21        97899-98035
            662-765             AC090058.21        100146-100249
            766-876             AC090058.21        102850-102960
            877-930             AC090058.21        104001-104054
            931-1143            AC090058.21        115871-116083
            1144-1247           AC090058.21        116725-116828
            1248-1460           AC090058.21        123546-123758
            1461-1509           AC090058.21        124993-125041
            1510-1671           AC090058.21        129370-129531
            1672-1793           AC090058.21        135826-135947
            1794-1962           AC090058.21        136410-136578
            1963-6441           AC090058.21        137937-142415
FEATURES             Location/Qualifiers
     source          1..6441
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.12"
     gene            1..6441
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="La ribonucleoprotein 4"
                     /db_xref="GeneID:113251"
                     /db_xref="HGNC:HGNC:24320"
                     /db_xref="MIM:618657"
     exon            1..144
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..2301
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="isoform a is encoded by transcript variant 1; c-Mpl
                     binding protein; La-related protein 4; La
                     ribonucleoprotein domain family member 4"
                     /codon_start=1
                     /product="la-related protein 4 isoform a"
                     /protein_id="NP_443111.4"
                     /db_xref="CCDS:CCDS41782.1"
                     /db_xref="GeneID:113251"
                     /db_xref="HGNC:HGNC:24320"
                     /db_xref="MIM:618657"
                     /translation="MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWH
                     EIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQ
                     IYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANM
                     EEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGL
                     FKSENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINT
                     FFAKNGYRLMDSSIYSHPIQTQAQYASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPY
                     FETPLAPFPNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGS
                     VSLGDGQLNRYSSRNFPAERHNPTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFR
                     GRRRREDDRISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVV
                     KGVYKEKDNEELTISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIE
                     DSSVQKDGLNQTTIPVSPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQ
                     KPPKEPSSVLVQPLRELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGN
                     IIPRGAAGKIREQRRQFSHRAIPQGVTRRNGKEQYVPPRSPK"
     exon            145..292
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            293..448
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            449..524
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            525..661
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            662..765
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            766..876
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            877..930
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1143
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1247
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1460
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1461..1509
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1671
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1793
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..1962
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1963..6441
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4392..4397
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="hexamer: AATAAA"
     polyA_site      4413
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="major polyA site"
     regulatory      6422..6427
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="hexamer: AATAAA"
     polyA_site      6441
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="major polyA site"
ORIGIN      
        1 agccgggtcc actgccgggt ggaggggcaa ggcgagtgtg tgtccttatc ctagcaattg
       61 gggcgcgggc ctgtgagcca gttggagttg cggcggcggg aacgattggg ctgagcagag
      121 gacgacatgt tgcttttcgt ggagcaggta gcatctaaag gaactggttt aaatcctaat
      181 gccaaagtat ggcaagaaat tgctcctgga aatactgatg ccaccccagt aactcatgga
      241 actgaaagct cttggcatga aatagcagct acatcaggtg ctcatcctga gggtaatgca
      301 gagctctcag aagatatatg taaagaatat gaagtaatgt attcttcatc ttgtgaaacc
      361 acaagaaata ctacaggcat tgaagaatca actgatggga tgattttagg accagaagat
      421 ctgagttacc aaatatatga tgtttccgga gaaagcaatt cagcagtttc tacagaagac
      481 ctaaaagaat gtctgaagaa acaattagaa ttctgttttt cacgagaaaa tttgtcaaag
      541 gatctttact tgatatctca aatggatagt gatcagttca tcccaatttg gacagttgcc
      601 aacatggaag aaataaaaaa gttgactaca gaccctgatc taattcttga agtgttaaga
      661 tcttctccca tggtacaagt tgatgagaag ggtgagaaag tgagaccaag tcataagcgt
      721 tgtattgtaa ttcttagaga gattcctgaa acaacaccaa tagaggaagt gaaaggtttg
      781 ttcaaaagtg aaaactgccc caaagtgata agctgtgagt ttgcacacaa tagcaactgg
      841 tatatcactt tccagtcaga cacagatgca caacaggctt ttaaatactt aagagaagaa
      901 gttaaaacat ttcagggcaa gccaattatg gcaaggataa aagccatcaa tacatttttt
      961 gctaagaatg gttatcgatt aatggattct agtatctata gtcaccccat tcaaactcaa
     1021 gcacagtatg cctccccagt ctttatgcag cctgtatata atcctcacca acagtactcg
     1081 gtctatagta ttgtgcctca gtcttggtct ccaaatccta caccttactt tgaaacacca
     1141 ctggctccct ttcccaatgg tagttttgtg aatggcttta attcgccagg atcttataaa
     1201 acaaatgctg ctgctatgaa tatgggtcga ccattccaaa aaaatcgtgt gaagcctcag
     1261 tttaggtcat ctggtggttc agaacactca acagagggct ctgtatcctt gggggatgga
     1321 cagttgaaca gatatagttc aagaaacttt ccagctgaac ggcataaccc cacagtaact
     1381 gggcatcagg agcaaactta ccttcagaag gagacttcca ctttgcaggt ggaacagaat
     1441 ggggactatg gtaggggcag gagaactctc ttcagaggtc gaagacgacg agaagatgac
     1501 aggatctcaa gacctcatcc ttcaacagct gaatcaaagg ctccaacacc aaagtttgac
     1561 ttattagcct caaattttcc acctttacct ggaagttcat caagaatgcc aggtgaactc
     1621 gttttggaga ataggatgtc tgatgttgtt aaaggtgtct acaaagaaaa ggataatgaa
     1681 gagttgacaa ttagttgccc agtgcctgca gatgagcaga cagaatgcac ttctgcccag
     1741 caactcaata tgagtaccag ttctccatgt gctgctgagc ttactgcatt aagcacaact
     1801 cagcaagaaa aggatctaat agaagattcc tctgttcaga aggatggtct caatcagaca
     1861 actataccag tttctcctcc aagtactaca aagccatcga gggcaagtac tgcttcacca
     1921 tgtaataata acataaatgc agctacagct gtggctctac aggaaccccg aaagttaagt
     1981 tatgctgaag tgtgccagaa gccccctaaa gagccatctt cagttcttgt gcagccacta
     2041 cgggaacttc gctccaatgt ggtgtctccc accaaaaatg aagacaatgg agctcctgag
     2101 aactccgttg agaaaccaca tgagaagcca gaagcaaggg ctagtaagga ttattctggc
     2161 ttccgaggca atataatccc caggggagca gcaggaaaaa tcagggaaca gagacgccag
     2221 tttagccata gggctatacc tcagggagtg actcgacgta atggcaaaga gcaatatgtg
     2281 ccacccagat caccaaagta aaaaacaaca aaactattca aaaacttcac tctcttccca
     2341 ttaaacttga actgtggcta tattgaactg ttttggaggg gagggggtag ccaggaagga
     2401 aacaagagaa agtacgtcca tttcattatg gattttggag ttgtgagtga taggatccca
     2461 aaattcatct ctaatgtggt ttttaaatgc tggaggattc caatcaatat aaatatatat
     2521 atatatatac acacacatat ataaaaagta taatttttct atttttgttt ttggttttaa
     2581 tttgcagaga tttgctgcca ggaatcaatt ttgagggttc agatttagct tggaagaaaa
     2641 aaaagaaaca tacatccttc agtataggag atgagggaat gagagaaaat attttttgaa
     2701 gaagcatttc tgtaaaatta gaaattactt tttttaatct atttaaagtt tggcttgaag
     2761 aatgccatct ctgactatat ggccttgtat tgcaaagcgg atcagtggct ggggtgcctg
     2821 ttgtgggtgt gagtgtgtac aagagcgatt gaagccaaat ctgttgtcat gttagtaaat
     2881 gatttgaaaa ctgaatgtaa tacttgagta gatttttttt tctagtttga aatttagtct
     2941 gtctttttga ccttactaat atttcattta acaagttgta aaactctgat tgtacttaga
     3001 gatgtgacta ccaatcagtt tgatactcaa ggaaaggggg ttattcaaga aattgaaaat
     3061 ttcatcttgg acctcagtgc ataggtcaaa tggatttcag aggtttaaac ttccctgtga
     3121 ttcccccgaa tacccccaaa atgagaaaca aaattttttt tcttactcca tttgttactc
     3181 tctgttcttt gactgcccac ccacagaaaa gcaaaataac caactaccta ctcaattgtg
     3241 tgtttgtaat tgctttgagc agtctagtca aatcatataa attgttctaa atttcagaat
     3301 tgaacattga agtattaact cttctgttca cacatttaga attttagctc ccaagatggt
     3361 agggcagact gaccgtacag taatttattt gtcgttagtg ttaaagatta agcatagtaa
     3421 ctgactctta agtgttaaat aatgtagaag taaaaaaatt ttttttaaag gcttaatttg
     3481 ggagggggga cttatttctg tttacagtgt attaccttcc ttccctcctc ttctcccccc
     3541 acacccaaca aaatacagtt tggaattcac tgaaacagta ccagcaagtc atgagatttt
     3601 ttagtaaaga tgagaaagat ggttgaagaa aattagtgca taatttctca gtgaataaag
     3661 ttgtagctct catatactaa atagacaagt ttacatgctg ttatttagaa aatgactaaa
     3721 atattaaaaa ccgtgttgtg ttaatctgtt ttaagtcata ccatgttcag agttctatgt
     3781 aaggtgggtt ttatttttct tttaagggat agtttgtaat agtaagaact gtcccatatg
     3841 ttagtaaatt acatatgtac aaattgaaac tgtaaattgt gaacactgga aagcaccatt
     3901 gtgacataga gtaaacatct tagtaatata ttaaagtgaa tgtaaatggt ggttaaaatt
     3961 acattactgt gaaattcatc ttccaactct aagttaagct ttggagatac atgttagtgg
     4021 ttaactgtta agagctttga aaacactgca catatctgta caagccagaa ttactatttc
     4081 tttgacttat tattagcttg gcagttgctt ttgatttgat tgttttatga catggtatac
     4141 tactatattt actcagtttg aaactattca tttctacaca ctatttttaa aaattgccta
     4201 ctaggtgaaa cataacaata aaactacctg tgctgaaatt tgggggaagt ttaggtcctt
     4261 taaaaaaaca tattaatcat tgactacatc tatgataaaa gtgcttattt tggtttacta
     4321 agataatgca gttggtggaa atgataaacg ttttaagtgt taacatcctt tgaatgcgtt
     4381 ggatttcaga gaataaacat tttgtaaaaa tcacttggta aggattataa acttaattac
     4441 tgcacttaaa atgaaacatt acttttttta aacaatgtgt cacaaatgta ggtctgtatt
     4501 acttgtatgc ttgtgtgact tactgttagt ccagctctaa aaatttaaag gttgtaattg
     4561 aaatacaaga aaagagcctt cttttagaag aaagcaagta tatttttgct tttacttcaa
     4621 atgttattta aagtagaaat ttaatttgta gatataacct ttaaaaattt tctcattaag
     4681 acaatgtttt taatttaatt tgcctcatta catctaatag ttcccatttg atggcatgta
     4741 tagggaagag tgagagagtg tgtgtgtgtg tatgtgtgtg taatatttat atatattcac
     4801 agtatgtatt tagcatttat tttattacag cagatttaaa gtttgtatct aaataatgcc
     4861 tatgagttgt gtgaagctct tggctttttt ccaacgttac tttgtaacta atgagggtgg
     4921 atgttcattg tagtttattt atttggttct ttagatggag gaatttaaaa aatcaaattt
     4981 ttctcttcac ctttatgact tgacatttcc ttgatctgtt ggaggctaaa agtaggtata
     5041 aatgatattg aatgttgggt atagtgatac tctgccatag ttcttactgc atgaagagaa
     5101 caagagtcac acaagttcac cactttgcac ttcatagaga aggtacatag agacattgca
     5161 aaacctgtct ccatttgcta tcctgataat taaggttttc ataataccta gggcctgtct
     5221 ctgagtaatt ttaattttgc caaatacact gacatttaaa atagtgatcc atctaaattt
     5281 ttttcagctg ggttttgagg aatataagag ctttcaatga taaaggtttg ttgtagttgt
     5341 cttatgtgct gaatttgcag atgatcagat gctgtgcaga attctgattt atttttgttt
     5401 cctaaaatta agatagcttg aatattattt cacattcctt tttctttttt aaataaacag
     5461 gtttgctttg gaaaggctta atgatggaat gttagcatct tcactagggt aaagaagaac
     5521 aaaaagaatg ttgctggaac gtaaaatagt atttaaaagt taatgaacac ttctctagtt
     5581 ttcttagtta tggccttaat aattagtctc ttggcttaaa tgtccactgg ttttactttg
     5641 acacagttga acaacactgg ggttaagtct ctggtattta ggctggcaat atatatatta
     5701 accatatttt aaaagtacca attttgtttt tacagaaaag ataaaactca aaagagaaca
     5761 gtgtattcct tctgaggggc ttttataaat tattaactat aatatatgat ggattttttc
     5821 ctaatttttt atatttcctt acaattttgg tggccattaa tttaacttta ggcttttggg
     5881 catatgctag tctgagcttc cgaaaagata catatatgtt tcccttttca ttagctgaat
     5941 gaggatattt taagaagttg aaagagaatt tattttcaag ttgtgagtaa atcctccttt
     6001 gaaattcacc tgattattag ataacttaaa gtttattttt aaaagctgac aactttttat
     6061 gaatcttcga gttgacagtt cctaaaagcg taactcagat attaatgggc tgtgtattaa
     6121 atggttttat tttcagtttt gcagcacaga acactgttga aatatccata tcaacttgat
     6181 ttttttaacc taattcaggt gtcctttgca tctcttaaat gttgggggtg ggggtcagag
     6241 ccagttatcc ggcttctgtt ttgtcgattg cttagatttg ttcctgttgt caaaactgtt
     6301 acccccaaaa ttggtgtgac acatgctcat gcataaaatg ttaaaatgag tacatccttg
     6361 tatttgtatt tgttttcaac atcgccaagg tgctatggga aattaacaaa attagaaaaa
     6421 aaataaaatt attaaaaagc a
//
