LOCUS       NM_001352311            6530 bp    mRNA    linear   PRI 10-FEB-2025
DEFINITION  Homo sapiens La ribonucleoprotein 4 (LARP4), transcript variant 15,
            mRNA.
ACCESSION   NM_001352311 XM_011537840
VERSION     NM_001352311.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6530)
  AUTHORS   Zhang,J., Yang,Y., Song,X., Xing,K. and Chen,Y.
  TITLE     Biological functions of Circular RNA_LARP4/ Upstream frameshift 1
            in development of gastric cancer
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 70 (4), 176-180 (2024)
   PUBMED   38678610
  REMARK    GeneRIF: Biological functions of Circular RNA_LARP4/ Upstream
            frameshift 1 in development of gastric cancer.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6530)
  AUTHORS   Lewis,B.M., Cho,C.Y., Her,H.L., Mizrahi,O., Hunter,T. and Yeo,G.W.
  TITLE     LARP4 is an RNA-binding protein that binds nuclear-encoded
            mitochondrial mRNAs to promote mitochondrial function
  JOURNAL   RNA 30 (3), 223-239 (2024)
   PUBMED   38164626
  REMARK    GeneRIF: LARP4 is an RNA-binding protein that binds nuclear-encoded
            mitochondrial mRNAs to promote mitochondrial function.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6530)
  AUTHORS   Lu,M., Gong,B., Wang,Y. and Li,J.
  TITLE     CircBNC2 affects epithelial ovarian cancer progression through the
            miR-223-3p/ LARP4 axis
  JOURNAL   Anticancer Drugs 34 (3), 384-394 (2023)
   PUBMED   36730544
  REMARK    GeneRIF: CircBNC2 affects epithelial ovarian cancer progression
            through the miR-223-3p/ LARP4 axis.
REFERENCE   4  (bases 1 to 6530)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   5  (bases 1 to 6530)
  AUTHORS   Mattijssen,S., Iben,J.R., Li,T., Coon,S.L. and Maraia,R.J.
  TITLE     Single molecule poly(A) tail-seq shows LARP4 opposes deadenylation
            throughout mRNA lifespan with most impact on short tails
  JOURNAL   Elife 9, e59186 (2020)
   PUBMED   32744499
  REMARK    GeneRIF: Single molecule poly(A) tail-seq shows LARP4 opposes
            deadenylation throughout mRNA lifespan with most impact on short
            tails.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6530)
  AUTHORS   Bai,S.W., Herrera-Abreu,M.T., Rohn,J.L., Racine,V., Tajadura,V.,
            Suryavanshi,N., Bechtel,S., Wiemann,S., Baum,B. and Ridley,A.J.
  TITLE     Identification and characterization of a set of conserved and new
            regulators of cytoskeletal organization, cell morphology and
            migration
  JOURNAL   BMC Biol 9, 54 (2011)
   PUBMED   21834987
  REMARK    Erratum:[BMC Biol. 2024 Oct 10;22(1):228. doi:
            10.1186/s12915-024-02036-3.. PMID: 39390519]
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6530)
  AUTHORS   Yang,R., Gaidamakov,S.A., Xie,J., Lee,J., Martino,L., Kozlov,G.,
            Crawford,A.K., Russo,A.N., Conte,M.R., Gehring,K. and Maraia,R.J.
  TITLE     La-related protein 4 binds poly(A), interacts with the
            poly(A)-binding protein MLLE domain via a variant PAM2w motif, and
            can promote mRNA stability
  JOURNAL   Mol Cell Biol 31 (3), 542-556 (2011)
   PUBMED   21098120
  REMARK    GeneRIF: LARP4 activity is integrated with other PAM2 protein
            activities by PABP as part of mRNA homeostasis.
REFERENCE   8  (bases 1 to 6530)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   9  (bases 1 to 6530)
  AUTHORS   Puigdecanet,E., Espinet,B., Villa,O., Florensa,L., Besses,C.,
            Serrano,S. and Sole,F.
  TITLE     Detection of abnormalities of PRV-1, TPO, and c-MPL genes detected
            by fluorescence in situ hybridization in essential thrombocythemia
  JOURNAL   Cancer Genet Cytogenet 167 (1), 39-42 (2006)
   PUBMED   16682284
  REMARK    GeneRIF: FISH study showed no cytogenetic abnormalities in any of
            the analyzed cases.
REFERENCE   10 (bases 1 to 6530)
  AUTHORS   Kralovics,R. and Skoda,R.C.
  TITLE     Molecular pathogenesis of Philadelphia chromosome negative
            myeloproliferative disorders
  JOURNAL   Blood Rev 19 (1), 1-13 (2005)
   PUBMED   15572213
  REMARK    GeneRIF: The c-MPL protein altered expression provide an
            opportunity to diagnose and identify subpopulations of MPD
            patients.
            Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC090058.21.
            
            On May 31, 2019 this sequence version replaced NM_001352311.1.
            
            Transcript Variant: This variant (15), as well as variants 13, 14,
            and 16-18, encodes isoform m.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.213801.1,
                                           SRR1803615.269216.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142348
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               AC090058.21        63296-63439
            145-233             AC090058.21        78757-78845
            234-381             AC090058.21        90173-90320
            382-537             AC090058.21        91346-91501
            538-613             AC090058.21        92906-92981
            614-750             AC090058.21        97899-98035
            751-854             AC090058.21        100146-100249
            855-965             AC090058.21        102850-102960
            966-1019            AC090058.21        104001-104054
            1020-1232           AC090058.21        115871-116083
            1233-1336           AC090058.21        116725-116828
            1337-1549           AC090058.21        123546-123758
            1550-1598           AC090058.21        124993-125041
            1599-1760           AC090058.21        129370-129531
            1761-1882           AC090058.21        135826-135947
            1883-2051           AC090058.21        136410-136578
            2052-6530           AC090058.21        137937-142415
FEATURES             Location/Qualifiers
     source          1..6530
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.12"
     gene            1..6530
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="La ribonucleoprotein 4"
                     /db_xref="GeneID:113251"
                     /db_xref="HGNC:HGNC:24320"
                     /db_xref="MIM:618657"
     exon            1..144
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            145..233
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            234..381
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            382..537
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     CDS             426..2390
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="isoform m is encoded by transcript variant 15;
                     c-Mpl binding protein; La-related protein 4; La
                     ribonucleoprotein domain family member 4"
                     /codon_start=1
                     /product="la-related protein 4 isoform m"
                     /protein_id="NP_001339240.1"
                     /db_xref="GeneID:113251"
                     /db_xref="HGNC:HGNC:24320"
                     /db_xref="MIM:618657"
                     /translation="MYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAV
                     STEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDL
                     ILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISC
                     EFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTFFAKNGYRLMDS
                     SIYSHPIQTQAQYASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGS
                     FVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYS
                     SRNFPAERHNPTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISR
                     PHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEEL
                     TISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQT
                     TIPVSPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQ
                     PLRELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIRE
                     QRRQFSHRAIPQGVTRRNGKEQYVPPRSPK"
     exon            538..613
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            614..750
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            751..854
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            855..965
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1019
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1232
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1336
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1549
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1598
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1599..1760
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1761..1882
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1883..2051
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            2052..6530
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4481..4486
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="hexamer: AATAAA"
     polyA_site      4502
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="major polyA site"
     regulatory      6511..6516
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="hexamer: AATAAA"
     polyA_site      6530
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="major polyA site"
ORIGIN      
        1 agccgggtcc actgccgggt ggaggggcaa ggcgagtgtg tgtccttatc ctagcaattg
       61 gggcgcgggc ctgtgagcca gttggagttg cggcggcggg aacgattggg ctgagcagag
      121 gacgacatgt tgcttttcgt ggagtgagaa tcagagcgtc tactgcacct ttcagatgac
      181 cgggtgccgt ggctcaacac ctataatccc agcacttggg atgggaggct aagcaggtag
      241 catctaaagg aactggttta aatcctaatg ccaaagtatg gcaagaaatt gctcctggaa
      301 atactgatgc caccccagta actcatggaa ctgaaagctc ttggcatgaa atagcagcta
      361 catcaggtgc tcatcctgag ggtaatgcag agctctcaga agatatatgt aaagaatatg
      421 aagtaatgta ttcttcatct tgtgaaacca caagaaatac tacaggcatt gaagaatcaa
      481 ctgatgggat gattttagga ccagaagatc tgagttacca aatatatgat gtttccggag
      541 aaagcaattc agcagtttct acagaagacc taaaagaatg tctgaagaaa caattagaat
      601 tctgtttttc acgagaaaat ttgtcaaagg atctttactt gatatctcaa atggatagtg
      661 atcagttcat cccaatttgg acagttgcca acatggaaga aataaaaaag ttgactacag
      721 accctgatct aattcttgaa gtgttaagat cttctcccat ggtacaagtt gatgagaagg
      781 gtgagaaagt gagaccaagt cataagcgtt gtattgtaat tcttagagag attcctgaaa
      841 caacaccaat agaggaagtg aaaggtttgt tcaaaagtga aaactgcccc aaagtgataa
      901 gctgtgagtt tgcacacaat agcaactggt atatcacttt ccagtcagac acagatgcac
      961 aacaggcttt taaatactta agagaagaag ttaaaacatt tcagggcaag ccaattatgg
     1021 caaggataaa agccatcaat acattttttg ctaagaatgg ttatcgatta atggattcta
     1081 gtatctatag tcaccccatt caaactcaag cacagtatgc ctccccagtc tttatgcagc
     1141 ctgtatataa tcctcaccaa cagtactcgg tctatagtat tgtgcctcag tcttggtctc
     1201 caaatcctac accttacttt gaaacaccac tggctccctt tcccaatggt agttttgtga
     1261 atggctttaa ttcgccagga tcttataaaa caaatgctgc tgctatgaat atgggtcgac
     1321 cattccaaaa aaatcgtgtg aagcctcagt ttaggtcatc tggtggttca gaacactcaa
     1381 cagagggctc tgtatccttg ggggatggac agttgaacag atatagttca agaaactttc
     1441 cagctgaacg gcataacccc acagtaactg ggcatcagga gcaaacttac cttcagaagg
     1501 agacttccac tttgcaggtg gaacagaatg gggactatgg taggggcagg agaactctct
     1561 tcagaggtcg aagacgacga gaagatgaca ggatctcaag acctcatcct tcaacagctg
     1621 aatcaaaggc tccaacacca aagtttgact tattagcctc aaattttcca cctttacctg
     1681 gaagttcatc aagaatgcca ggtgaactcg ttttggagaa taggatgtct gatgttgtta
     1741 aaggtgtcta caaagaaaag gataatgaag agttgacaat tagttgccca gtgcctgcag
     1801 atgagcagac agaatgcact tctgcccagc aactcaatat gagtaccagt tctccatgtg
     1861 ctgctgagct tactgcatta agcacaactc agcaagaaaa ggatctaata gaagattcct
     1921 ctgttcagaa ggatggtctc aatcagacaa ctataccagt ttctcctcca agtactacaa
     1981 agccatcgag ggcaagtact gcttcaccat gtaataataa cataaatgca gctacagctg
     2041 tggctctaca ggaaccccga aagttaagtt atgctgaagt gtgccagaag ccccctaaag
     2101 agccatcttc agttcttgtg cagccactac gggaacttcg ctccaatgtg gtgtctccca
     2161 ccaaaaatga agacaatgga gctcctgaga actccgttga gaaaccacat gagaagccag
     2221 aagcaagggc tagtaaggat tattctggct tccgaggcaa tataatcccc aggggagcag
     2281 caggaaaaat cagggaacag agacgccagt ttagccatag ggctatacct cagggagtga
     2341 ctcgacgtaa tggcaaagag caatatgtgc cacccagatc accaaagtaa aaaacaacaa
     2401 aactattcaa aaacttcact ctcttcccat taaacttgaa ctgtggctat attgaactgt
     2461 tttggagggg agggggtagc caggaaggaa acaagagaaa gtacgtccat ttcattatgg
     2521 attttggagt tgtgagtgat aggatcccaa aattcatctc taatgtggtt tttaaatgct
     2581 ggaggattcc aatcaatata aatatatata tatatataca cacacatata taaaaagtat
     2641 aatttttcta tttttgtttt tggttttaat ttgcagagat ttgctgccag gaatcaattt
     2701 tgagggttca gatttagctt ggaagaaaaa aaagaaacat acatccttca gtataggaga
     2761 tgagggaatg agagaaaata ttttttgaag aagcatttct gtaaaattag aaattacttt
     2821 ttttaatcta tttaaagttt ggcttgaaga atgccatctc tgactatatg gccttgtatt
     2881 gcaaagcgga tcagtggctg gggtgcctgt tgtgggtgtg agtgtgtaca agagcgattg
     2941 aagccaaatc tgttgtcatg ttagtaaatg atttgaaaac tgaatgtaat acttgagtag
     3001 attttttttt ctagtttgaa atttagtctg tctttttgac cttactaata tttcatttaa
     3061 caagttgtaa aactctgatt gtacttagag atgtgactac caatcagttt gatactcaag
     3121 gaaagggggt tattcaagaa attgaaaatt tcatcttgga cctcagtgca taggtcaaat
     3181 ggatttcaga ggtttaaact tccctgtgat tcccccgaat acccccaaaa tgagaaacaa
     3241 aatttttttt cttactccat ttgttactct ctgttctttg actgcccacc cacagaaaag
     3301 caaaataacc aactacctac tcaattgtgt gtttgtaatt gctttgagca gtctagtcaa
     3361 atcatataaa ttgttctaaa tttcagaatt gaacattgaa gtattaactc ttctgttcac
     3421 acatttagaa ttttagctcc caagatggta gggcagactg accgtacagt aatttatttg
     3481 tcgttagtgt taaagattaa gcatagtaac tgactcttaa gtgttaaata atgtagaagt
     3541 aaaaaaattt tttttaaagg cttaatttgg gaggggggac ttatttctgt ttacagtgta
     3601 ttaccttcct tccctcctct tctcccccca cacccaacaa aatacagttt ggaattcact
     3661 gaaacagtac cagcaagtca tgagattttt tagtaaagat gagaaagatg gttgaagaaa
     3721 attagtgcat aatttctcag tgaataaagt tgtagctctc atatactaaa tagacaagtt
     3781 tacatgctgt tatttagaaa atgactaaaa tattaaaaac cgtgttgtgt taatctgttt
     3841 taagtcatac catgttcaga gttctatgta aggtgggttt tatttttctt ttaagggata
     3901 gtttgtaata gtaagaactg tcccatatgt tagtaaatta catatgtaca aattgaaact
     3961 gtaaattgtg aacactggaa agcaccattg tgacatagag taaacatctt agtaatatat
     4021 taaagtgaat gtaaatggtg gttaaaatta cattactgtg aaattcatct tccaactcta
     4081 agttaagctt tggagataca tgttagtggt taactgttaa gagctttgaa aacactgcac
     4141 atatctgtac aagccagaat tactatttct ttgacttatt attagcttgg cagttgcttt
     4201 tgatttgatt gttttatgac atggtatact actatattta ctcagtttga aactattcat
     4261 ttctacacac tatttttaaa aattgcctac taggtgaaac ataacaataa aactacctgt
     4321 gctgaaattt gggggaagtt taggtccttt aaaaaaacat attaatcatt gactacatct
     4381 atgataaaag tgcttatttt ggtttactaa gataatgcag ttggtggaaa tgataaacgt
     4441 tttaagtgtt aacatccttt gaatgcgttg gatttcagag aataaacatt ttgtaaaaat
     4501 cacttggtaa ggattataaa cttaattact gcacttaaaa tgaaacatta ctttttttaa
     4561 acaatgtgtc acaaatgtag gtctgtatta cttgtatgct tgtgtgactt actgttagtc
     4621 cagctctaaa aatttaaagg ttgtaattga aatacaagaa aagagccttc ttttagaaga
     4681 aagcaagtat atttttgctt ttacttcaaa tgttatttaa agtagaaatt taatttgtag
     4741 atataacctt taaaaatttt ctcattaaga caatgttttt aatttaattt gcctcattac
     4801 atctaatagt tcccatttga tggcatgtat agggaagagt gagagagtgt gtgtgtgtgt
     4861 atgtgtgtgt aatatttata tatattcaca gtatgtattt agcatttatt ttattacagc
     4921 agatttaaag tttgtatcta aataatgcct atgagttgtg tgaagctctt ggcttttttc
     4981 caacgttact ttgtaactaa tgagggtgga tgttcattgt agtttattta tttggttctt
     5041 tagatggagg aatttaaaaa atcaaatttt tctcttcacc tttatgactt gacatttcct
     5101 tgatctgttg gaggctaaaa gtaggtataa atgatattga atgttgggta tagtgatact
     5161 ctgccatagt tcttactgca tgaagagaac aagagtcaca caagttcacc actttgcact
     5221 tcatagagaa ggtacataga gacattgcaa aacctgtctc catttgctat cctgataatt
     5281 aaggttttca taatacctag ggcctgtctc tgagtaattt taattttgcc aaatacactg
     5341 acatttaaaa tagtgatcca tctaaatttt tttcagctgg gttttgagga atataagagc
     5401 tttcaatgat aaaggtttgt tgtagttgtc ttatgtgctg aatttgcaga tgatcagatg
     5461 ctgtgcagaa ttctgattta tttttgtttc ctaaaattaa gatagcttga atattatttc
     5521 acattccttt ttctttttta aataaacagg tttgctttgg aaaggcttaa tgatggaatg
     5581 ttagcatctt cactagggta aagaagaaca aaaagaatgt tgctggaacg taaaatagta
     5641 tttaaaagtt aatgaacact tctctagttt tcttagttat ggccttaata attagtctct
     5701 tggcttaaat gtccactggt tttactttga cacagttgaa caacactggg gttaagtctc
     5761 tggtatttag gctggcaata tatatattaa ccatatttta aaagtaccaa ttttgttttt
     5821 acagaaaaga taaaactcaa aagagaacag tgtattcctt ctgaggggct tttataaatt
     5881 attaactata atatatgatg gattttttcc taatttttta tatttcctta caattttggt
     5941 ggccattaat ttaactttag gcttttgggc atatgctagt ctgagcttcc gaaaagatac
     6001 atatatgttt cccttttcat tagctgaatg aggatatttt aagaagttga aagagaattt
     6061 attttcaagt tgtgagtaaa tcctcctttg aaattcacct gattattaga taacttaaag
     6121 tttattttta aaagctgaca actttttatg aatcttcgag ttgacagttc ctaaaagcgt
     6181 aactcagata ttaatgggct gtgtattaaa tggttttatt ttcagttttg cagcacagaa
     6241 cactgttgaa atatccatat caacttgatt tttttaacct aattcaggtg tcctttgcat
     6301 ctcttaaatg ttgggggtgg gggtcagagc cagttatccg gcttctgttt tgtcgattgc
     6361 ttagatttgt tcctgttgtc aaaactgtta cccccaaaat tggtgtgaca catgctcatg
     6421 cataaaatgt taaaatgagt acatccttgt atttgtattt gttttcaaca tcgccaaggt
     6481 gctatgggaa attaacaaaa ttagaaaaaa aataaaatta ttaaaaagca
//
