LOCUS       NM_001352306            6526 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens La ribonucleoprotein 4 (LARP4), transcript variant 10,
            mRNA.
ACCESSION   NM_001352306
VERSION     NM_001352306.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6526)
  AUTHORS   Zhang,J., Yang,Y., Song,X., Xing,K. and Chen,Y.
  TITLE     Biological functions of Circular RNA_LARP4/ Upstream frameshift 1
            in development of gastric cancer
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 70 (4), 176-180 (2024)
   PUBMED   38678610
  REMARK    GeneRIF: Biological functions of Circular RNA_LARP4/ Upstream
            frameshift 1 in development of gastric cancer.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6526)
  AUTHORS   Lewis,B.M., Cho,C.Y., Her,H.L., Mizrahi,O., Hunter,T. and Yeo,G.W.
  TITLE     LARP4 is an RNA-binding protein that binds nuclear-encoded
            mitochondrial mRNAs to promote mitochondrial function
  JOURNAL   RNA 30 (3), 223-239 (2024)
   PUBMED   38164626
  REMARK    GeneRIF: LARP4 is an RNA-binding protein that binds nuclear-encoded
            mitochondrial mRNAs to promote mitochondrial function.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6526)
  AUTHORS   Lu,M., Gong,B., Wang,Y. and Li,J.
  TITLE     CircBNC2 affects epithelial ovarian cancer progression through the
            miR-223-3p/ LARP4 axis
  JOURNAL   Anticancer Drugs 34 (3), 384-394 (2023)
   PUBMED   36730544
  REMARK    GeneRIF: CircBNC2 affects epithelial ovarian cancer progression
            through the miR-223-3p/ LARP4 axis.
REFERENCE   4  (bases 1 to 6526)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   5  (bases 1 to 6526)
  AUTHORS   Mattijssen,S., Iben,J.R., Li,T., Coon,S.L. and Maraia,R.J.
  TITLE     Single molecule poly(A) tail-seq shows LARP4 opposes deadenylation
            throughout mRNA lifespan with most impact on short tails
  JOURNAL   Elife 9, e59186 (2020)
   PUBMED   32744499
  REMARK    GeneRIF: Single molecule poly(A) tail-seq shows LARP4 opposes
            deadenylation throughout mRNA lifespan with most impact on short
            tails.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6526)
  AUTHORS   Bai,S.W., Herrera-Abreu,M.T., Rohn,J.L., Racine,V., Tajadura,V.,
            Suryavanshi,N., Bechtel,S., Wiemann,S., Baum,B. and Ridley,A.J.
  TITLE     Identification and characterization of a set of conserved and new
            regulators of cytoskeletal organization, cell morphology and
            migration
  JOURNAL   BMC Biol 9, 54 (2011)
   PUBMED   21834987
  REMARK    Erratum:[BMC Biol. 2024 Oct 10;22(1):228. doi:
            10.1186/s12915-024-02036-3.. PMID: 39390519]
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6526)
  AUTHORS   Yang,R., Gaidamakov,S.A., Xie,J., Lee,J., Martino,L., Kozlov,G.,
            Crawford,A.K., Russo,A.N., Conte,M.R., Gehring,K. and Maraia,R.J.
  TITLE     La-related protein 4 binds poly(A), interacts with the
            poly(A)-binding protein MLLE domain via a variant PAM2w motif, and
            can promote mRNA stability
  JOURNAL   Mol Cell Biol 31 (3), 542-556 (2011)
   PUBMED   21098120
  REMARK    GeneRIF: LARP4 activity is integrated with other PAM2 protein
            activities by PABP as part of mRNA homeostasis.
REFERENCE   8  (bases 1 to 6526)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   9  (bases 1 to 6526)
  AUTHORS   Puigdecanet,E., Espinet,B., Villa,O., Florensa,L., Besses,C.,
            Serrano,S. and Sole,F.
  TITLE     Detection of abnormalities of PRV-1, TPO, and c-MPL genes detected
            by fluorescence in situ hybridization in essential thrombocythemia
  JOURNAL   Cancer Genet Cytogenet 167 (1), 39-42 (2006)
   PUBMED   16682284
  REMARK    GeneRIF: FISH study showed no cytogenetic abnormalities in any of
            the analyzed cases.
REFERENCE   10 (bases 1 to 6526)
  AUTHORS   Kralovics,R. and Skoda,R.C.
  TITLE     Molecular pathogenesis of Philadelphia chromosome negative
            myeloproliferative disorders
  JOURNAL   Blood Rev 19 (1), 1-13 (2005)
   PUBMED   15572213
  REMARK    GeneRIF: The c-MPL protein altered expression provide an
            opportunity to diagnose and identify subpopulations of MPD
            patients.
            Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC090058.21.
            
            On May 31, 2019 this sequence version replaced NM_001352306.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.57241.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145313, SAMEA2158188
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               AC090058.21        63296-63439
            145-283             AC090058.21        65086-65224
            284-431             AC090058.21        90173-90320
            432-587             AC090058.21        91346-91501
            588-663             AC090058.21        92906-92981
            664-800             AC090058.21        97899-98035
            801-904             AC090058.21        100146-100249
            905-1015            AC090058.21        102850-102960
            1016-1228           AC090058.21        115871-116083
            1229-1332           AC090058.21        116725-116828
            1333-1545           AC090058.21        123546-123758
            1546-1594           AC090058.21        124993-125041
            1595-1756           AC090058.21        129370-129531
            1757-1878           AC090058.21        135826-135947
            1879-2047           AC090058.21        136410-136578
            2048-6526           AC090058.21        137937-142415
FEATURES             Location/Qualifiers
     source          1..6526
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.12"
     gene            1..6526
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="La ribonucleoprotein 4"
                     /db_xref="GeneID:113251"
                     /db_xref="HGNC:HGNC:24320"
                     /db_xref="MIM:618657"
     exon            1..144
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            145..283
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..2386
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="isoform j is encoded by transcript variant 10;
                     c-Mpl binding protein; La-related protein 4; La
                     ribonucleoprotein domain family member 4"
                     /codon_start=1
                     /product="la-related protein 4 isoform j"
                     /protein_id="NP_001339235.1"
                     /db_xref="GeneID:113251"
                     /db_xref="HGNC:HGNC:24320"
                     /db_xref="MIM:618657"
                     /translation="MDGMLAIQACPTPQQVASKGTGLNPNAKVWQEIAPGNTDATPVT
                     HGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMIL
                     GPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFI
                     PIWTVANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETT
                     PIEEVKGLFKSENCPKVISCEFAHNSNWYITFQSDTDAQQARIKAINTFFAKNGYRLM
                     DSSIYSHPIQTQAQYASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPN
                     GSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNR
                     YSSRNFPAERHNPTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRI
                     SRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNE
                     ELTISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLN
                     QTTIPVSPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVL
                     VQPLRELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKI
                     REQRRQFSHRAIPQGVTRRNGKEQYVPPRSPK"
     exon            284..431
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            432..587
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            588..663
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            664..800
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            801..904
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1015
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1228
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1332
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1545
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1594
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..1756
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1757..1878
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2047
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..6526
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4477..4482
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="hexamer: AATAAA"
     polyA_site      4498
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="major polyA site"
     regulatory      6507..6512
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="hexamer: AATAAA"
     polyA_site      6526
                     /gene="LARP4"
                     /gene_synonym="PP13296"
                     /note="major polyA site"
ORIGIN      
        1 agccgggtcc actgccgggt ggaggggcaa ggcgagtgtg tgtccttatc ctagcaattg
       61 gggcgcgggc ctgtgagcca gttggagttg cggcggcggg aacgattggg ctgagcagag
      121 gacgacatgt tgcttttcgt ggagatgaca aaaccgagcc ccagaggtta aagtaacttt
      181 acttagtaaa agtaaagtag tttaactggg atttagatcc aggtcatgct gatgtcaaat
      241 catggacggg atgttagcaa ttcaggcctg tccgactccc cagcaggtag catctaaagg
      301 aactggttta aatcctaatg ccaaagtatg gcaagaaatt gctcctggaa atactgatgc
      361 caccccagta actcatggaa ctgaaagctc ttggcatgaa atagcagcta catcaggtgc
      421 tcatcctgag ggtaatgcag agctctcaga agatatatgt aaagaatatg aagtaatgta
      481 ttcttcatct tgtgaaacca caagaaatac tacaggcatt gaagaatcaa ctgatgggat
      541 gattttagga ccagaagatc tgagttacca aatatatgat gtttccggag aaagcaattc
      601 agcagtttct acagaagacc taaaagaatg tctgaagaaa caattagaat tctgtttttc
      661 acgagaaaat ttgtcaaagg atctttactt gatatctcaa atggatagtg atcagttcat
      721 cccaatttgg acagttgcca acatggaaga aataaaaaag ttgactacag accctgatct
      781 aattcttgaa gtgttaagat cttctcccat ggtacaagtt gatgagaagg gtgagaaagt
      841 gagaccaagt cataagcgtt gtattgtaat tcttagagag attcctgaaa caacaccaat
      901 agaggaagtg aaaggtttgt tcaaaagtga aaactgcccc aaagtgataa gctgtgagtt
      961 tgcacacaat agcaactggt atatcacttt ccagtcagac acagatgcac aacaggcaag
     1021 gataaaagcc atcaatacat tttttgctaa gaatggttat cgattaatgg attctagtat
     1081 ctatagtcac cccattcaaa ctcaagcaca gtatgcctcc ccagtcttta tgcagcctgt
     1141 atataatcct caccaacagt actcggtcta tagtattgtg cctcagtctt ggtctccaaa
     1201 tcctacacct tactttgaaa caccactggc tccctttccc aatggtagtt ttgtgaatgg
     1261 ctttaattcg ccaggatctt ataaaacaaa tgctgctgct atgaatatgg gtcgaccatt
     1321 ccaaaaaaat cgtgtgaagc ctcagtttag gtcatctggt ggttcagaac actcaacaga
     1381 gggctctgta tccttggggg atggacagtt gaacagatat agttcaagaa actttccagc
     1441 tgaacggcat aaccccacag taactgggca tcaggagcaa acttaccttc agaaggagac
     1501 ttccactttg caggtggaac agaatgggga ctatggtagg ggcaggagaa ctctcttcag
     1561 aggtcgaaga cgacgagaag atgacaggat ctcaagacct catccttcaa cagctgaatc
     1621 aaaggctcca acaccaaagt ttgacttatt agcctcaaat tttccacctt tacctggaag
     1681 ttcatcaaga atgccaggtg aactcgtttt ggagaatagg atgtctgatg ttgttaaagg
     1741 tgtctacaaa gaaaaggata atgaagagtt gacaattagt tgcccagtgc ctgcagatga
     1801 gcagacagaa tgcacttctg cccagcaact caatatgagt accagttctc catgtgctgc
     1861 tgagcttact gcattaagca caactcagca agaaaaggat ctaatagaag attcctctgt
     1921 tcagaaggat ggtctcaatc agacaactat accagtttct cctccaagta ctacaaagcc
     1981 atcgagggca agtactgctt caccatgtaa taataacata aatgcagcta cagctgtggc
     2041 tctacaggaa ccccgaaagt taagttatgc tgaagtgtgc cagaagcccc ctaaagagcc
     2101 atcttcagtt cttgtgcagc cactacggga acttcgctcc aatgtggtgt ctcccaccaa
     2161 aaatgaagac aatggagctc ctgagaactc cgttgagaaa ccacatgaga agccagaagc
     2221 aagggctagt aaggattatt ctggcttccg aggcaatata atccccaggg gagcagcagg
     2281 aaaaatcagg gaacagagac gccagtttag ccatagggct atacctcagg gagtgactcg
     2341 acgtaatggc aaagagcaat atgtgccacc cagatcacca aagtaaaaaa caacaaaact
     2401 attcaaaaac ttcactctct tcccattaaa cttgaactgt ggctatattg aactgttttg
     2461 gaggggaggg ggtagccagg aaggaaacaa gagaaagtac gtccatttca ttatggattt
     2521 tggagttgtg agtgatagga tcccaaaatt catctctaat gtggttttta aatgctggag
     2581 gattccaatc aatataaata tatatatata tatacacaca catatataaa aagtataatt
     2641 tttctatttt tgtttttggt tttaatttgc agagatttgc tgccaggaat caattttgag
     2701 ggttcagatt tagcttggaa gaaaaaaaag aaacatacat ccttcagtat aggagatgag
     2761 ggaatgagag aaaatatttt ttgaagaagc atttctgtaa aattagaaat tacttttttt
     2821 aatctattta aagtttggct tgaagaatgc catctctgac tatatggcct tgtattgcaa
     2881 agcggatcag tggctggggt gcctgttgtg ggtgtgagtg tgtacaagag cgattgaagc
     2941 caaatctgtt gtcatgttag taaatgattt gaaaactgaa tgtaatactt gagtagattt
     3001 ttttttctag tttgaaattt agtctgtctt tttgacctta ctaatatttc atttaacaag
     3061 ttgtaaaact ctgattgtac ttagagatgt gactaccaat cagtttgata ctcaaggaaa
     3121 gggggttatt caagaaattg aaaatttcat cttggacctc agtgcatagg tcaaatggat
     3181 ttcagaggtt taaacttccc tgtgattccc ccgaataccc ccaaaatgag aaacaaaatt
     3241 ttttttctta ctccatttgt tactctctgt tctttgactg cccacccaca gaaaagcaaa
     3301 ataaccaact acctactcaa ttgtgtgttt gtaattgctt tgagcagtct agtcaaatca
     3361 tataaattgt tctaaatttc agaattgaac attgaagtat taactcttct gttcacacat
     3421 ttagaatttt agctcccaag atggtagggc agactgaccg tacagtaatt tatttgtcgt
     3481 tagtgttaaa gattaagcat agtaactgac tcttaagtgt taaataatgt agaagtaaaa
     3541 aaattttttt taaaggctta atttgggagg ggggacttat ttctgtttac agtgtattac
     3601 cttccttccc tcctcttctc cccccacacc caacaaaata cagtttggaa ttcactgaaa
     3661 cagtaccagc aagtcatgag attttttagt aaagatgaga aagatggttg aagaaaatta
     3721 gtgcataatt tctcagtgaa taaagttgta gctctcatat actaaataga caagtttaca
     3781 tgctgttatt tagaaaatga ctaaaatatt aaaaaccgtg ttgtgttaat ctgttttaag
     3841 tcataccatg ttcagagttc tatgtaaggt gggttttatt tttcttttaa gggatagttt
     3901 gtaatagtaa gaactgtccc atatgttagt aaattacata tgtacaaatt gaaactgtaa
     3961 attgtgaaca ctggaaagca ccattgtgac atagagtaaa catcttagta atatattaaa
     4021 gtgaatgtaa atggtggtta aaattacatt actgtgaaat tcatcttcca actctaagtt
     4081 aagctttgga gatacatgtt agtggttaac tgttaagagc tttgaaaaca ctgcacatat
     4141 ctgtacaagc cagaattact atttctttga cttattatta gcttggcagt tgcttttgat
     4201 ttgattgttt tatgacatgg tatactacta tatttactca gtttgaaact attcatttct
     4261 acacactatt tttaaaaatt gcctactagg tgaaacataa caataaaact acctgtgctg
     4321 aaatttgggg gaagtttagg tcctttaaaa aaacatatta atcattgact acatctatga
     4381 taaaagtgct tattttggtt tactaagata atgcagttgg tggaaatgat aaacgtttta
     4441 agtgttaaca tcctttgaat gcgttggatt tcagagaata aacattttgt aaaaatcact
     4501 tggtaaggat tataaactta attactgcac ttaaaatgaa acattacttt ttttaaacaa
     4561 tgtgtcacaa atgtaggtct gtattacttg tatgcttgtg tgacttactg ttagtccagc
     4621 tctaaaaatt taaaggttgt aattgaaata caagaaaaga gccttctttt agaagaaagc
     4681 aagtatattt ttgcttttac ttcaaatgtt atttaaagta gaaatttaat ttgtagatat
     4741 aacctttaaa aattttctca ttaagacaat gtttttaatt taatttgcct cattacatct
     4801 aatagttccc atttgatggc atgtataggg aagagtgaga gagtgtgtgt gtgtgtatgt
     4861 gtgtgtaata tttatatata ttcacagtat gtatttagca tttattttat tacagcagat
     4921 ttaaagtttg tatctaaata atgcctatga gttgtgtgaa gctcttggct tttttccaac
     4981 gttactttgt aactaatgag ggtggatgtt cattgtagtt tatttatttg gttctttaga
     5041 tggaggaatt taaaaaatca aatttttctc ttcaccttta tgacttgaca tttccttgat
     5101 ctgttggagg ctaaaagtag gtataaatga tattgaatgt tgggtatagt gatactctgc
     5161 catagttctt actgcatgaa gagaacaaga gtcacacaag ttcaccactt tgcacttcat
     5221 agagaaggta catagagaca ttgcaaaacc tgtctccatt tgctatcctg ataattaagg
     5281 ttttcataat acctagggcc tgtctctgag taattttaat tttgccaaat acactgacat
     5341 ttaaaatagt gatccatcta aatttttttc agctgggttt tgaggaatat aagagctttc
     5401 aatgataaag gtttgttgta gttgtcttat gtgctgaatt tgcagatgat cagatgctgt
     5461 gcagaattct gatttatttt tgtttcctaa aattaagata gcttgaatat tatttcacat
     5521 tcctttttct tttttaaata aacaggtttg ctttggaaag gcttaatgat ggaatgttag
     5581 catcttcact agggtaaaga agaacaaaaa gaatgttgct ggaacgtaaa atagtattta
     5641 aaagttaatg aacacttctc tagttttctt agttatggcc ttaataatta gtctcttggc
     5701 ttaaatgtcc actggtttta ctttgacaca gttgaacaac actggggtta agtctctggt
     5761 atttaggctg gcaatatata tattaaccat attttaaaag taccaatttt gtttttacag
     5821 aaaagataaa actcaaaaga gaacagtgta ttccttctga ggggctttta taaattatta
     5881 actataatat atgatggatt ttttcctaat tttttatatt tccttacaat tttggtggcc
     5941 attaatttaa ctttaggctt ttgggcatat gctagtctga gcttccgaaa agatacatat
     6001 atgtttccct tttcattagc tgaatgagga tattttaaga agttgaaaga gaatttattt
     6061 tcaagttgtg agtaaatcct cctttgaaat tcacctgatt attagataac ttaaagttta
     6121 tttttaaaag ctgacaactt tttatgaatc ttcgagttga cagttcctaa aagcgtaact
     6181 cagatattaa tgggctgtgt attaaatggt tttattttca gttttgcagc acagaacact
     6241 gttgaaatat ccatatcaac ttgatttttt taacctaatt caggtgtcct ttgcatctct
     6301 taaatgttgg gggtgggggt cagagccagt tatccggctt ctgttttgtc gattgcttag
     6361 atttgttcct gttgtcaaaa ctgttacccc caaaattggt gtgacacatg ctcatgcata
     6421 aaatgttaaa atgagtacat ccttgtattt gtatttgttt tcaacatcgc caaggtgcta
     6481 tgggaaatta acaaaattag aaaaaaaata aaattattaa aaagca
//
