LOCUS       NM_198129              10651 bp    mRNA    linear   PRI 23-JUL-2024
DEFINITION  Homo sapiens laminin subunit alpha 3 (LAMA3), transcript variant 1,
            mRNA.
ACCESSION   NM_198129
VERSION     NM_198129.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10651)
  AUTHORS   Chen,C.X., Zhang,Y.L., Huang,Y.Z. and Li,L.
  TITLE     [Clinical and bioinformatics analysis of the relationship between
            LAMA3 DNA methylation expression and platinum resistance and
            prognosis in epithelial ovarian cancer]
  JOURNAL   Zhonghua Fu Chan Ke Za Zhi 59 (6), 454-464 (2024)
   PUBMED   38951081
  REMARK    GeneRIF: [Clinical and bioinformatics analysis of the relationship
            between LAMA3 DNA methylation expression and platinum resistance
            and prognosis in epithelial ovarian cancer].
REFERENCE   2  (bases 1 to 10651)
  AUTHORS   Hamill,K.J., Langbein,L., Jones,J.C. and McLean,W.H.
  TITLE     Identification of a novel family of laminin N-terminal alternate
            splice isoforms: structural and functional characterization
  JOURNAL   J Biol Chem 284 (51), 35588-35596 (2009)
   PUBMED   19773554
  REMARK    GeneRIF: immunofluorescence analyses revealed a basement membrane
            staining in epithelial tissue for LaNt alpha3 and LaNt alpha3
            localized along the substratum-associated surface of cultured
            keratinocytes.
REFERENCE   3  (bases 1 to 10651)
  AUTHORS   Kariya,Y., Yasuda,C., Nakashima,Y., Ishida,K., Tsubota,Y. and
            Miyazaki,K.
  TITLE     Characterization of laminin 5B and NH2-terminal proteolytic
            fragment of its alpha3B chain: promotion of cellular adhesion,
            migration, and proliferation
  JOURNAL   J Biol Chem 279 (23), 24774-24784 (2004)
   PUBMED   15044476
  REMARK    GeneRIF: Characterization of laminin 5B and NH2-terminal
            proteolytic fragment of its alpha3B chain
REFERENCE   4  (bases 1 to 10651)
  AUTHORS   McLean,W.H., Irvine,A.D., Hamill,K.J., Whittock,N.V.,
            Coleman-Campbell,C.M., Mellerio,J.E., Ashton,G.S.,
            Dopping-Hepenstal,P.J., Eady,R.A., Jamil,T., Phillips,R.,
            Shabbir,S.G., Haroon,T.S., Khurshid,K., Moore,J.E., Page,B.,
            Darling,J., Atherton,D.J., Van Steensel,M.A., Munro,C.S.,
            Smith,F.J. and McGrath,J.A.
  TITLE     An unusual N-terminal deletion of the laminin alpha3a isoform leads
            to the chronic granulation tissue disorder laryngo-onycho-cutaneous
            syndrome
  JOURNAL   Hum Mol Genet 12 (18), 2395-2409 (2003)
   PUBMED   12915477
  REMARK    Erratum:[Hum Mol Genet. 2004 Feb 1;13(3):365. Phillips Rodney J
            [corrected to Phillips Roderic J]]
REFERENCE   5  (bases 1 to 10651)
  AUTHORS   Doliana,R., Bellina,I., Bucciotti,F., Mongiat,M., Perris,R. and
            Colombatti,A.
  TITLE     The human alpha3b is a 'full-sized' laminin chain variant with a
            more widespread tissue expression than the truncated alpha3a
  JOURNAL   FEBS Lett 417 (1), 65-70 (1997)
   PUBMED   9395076
REFERENCE   6  (bases 1 to 10651)
  AUTHORS   Vidal,F., Baudoin,C., Miquel,C., Galliano,M.F., Christiano,A.M.,
            Uitto,J., Ortonne,J.P. and Meneguzzi,G.
  TITLE     Cloning of the laminin alpha 3 chain gene (LAMA3) and
            identification of a homozygous deletion in a patient with Herlitz
            junctional epidermolysis bullosa
  JOURNAL   Genomics 30 (2), 273-280 (1995)
   PUBMED   8586427
REFERENCE   7  (bases 1 to 10651)
  AUTHORS   Rousselle,P., Golbik,R., van der Rest,M. and Aumailley,M.
  TITLE     Structural requirement for cell adhesion to kalinin (laminin-5)
  JOURNAL   J Biol Chem 270 (23), 13766-13770 (1995)
   PUBMED   7775432
REFERENCE   8  (bases 1 to 10651)
  AUTHORS   Kivirikko,S., McGrath,J.A., Baudoin,C., Aberdam,D., Ciatti,S.,
            Dunnill,M.G., McMillan,J.R., Eady,R.A., Ortonne,J.P., Meneguzzi,G.
            et al.
  TITLE     A homozygous nonsense mutation in the alpha 3 chain gene of laminin
            5 (LAMA3) in lethal (Herlitz) junctional epidermolysis bullosa
  JOURNAL   Hum Mol Genet 4 (5), 959-962 (1995)
   PUBMED   7633458
REFERENCE   9  (bases 1 to 10651)
  AUTHORS   Ryan,M.C., Tizard,R., VanDevanter,D.R. and Carter,W.G.
  TITLE     Cloning of the LamA3 gene encoding the alpha 3 chain of the
            adhesive ligand epiligrin. Expression in wound repair
  JOURNAL   J Biol Chem 269 (36), 22779-22787 (1994)
   PUBMED   8077230
REFERENCE   10 (bases 1 to 10651)
  AUTHORS   Pfendner,E.G. and Lucky,A.W.
  TITLE     Junctional Epidermolysis Bullosa
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH,
            Gripp KW and Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301304
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC067796.11, AB107369.1 and
            AC010754.10.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Mar 31, 2020 this sequence version replaced NM_198129.3.
            
            Summary: The protein encoded by this gene belongs to the laminin
            family of secreted molecules. Laminins are heterotrimeric molecules
            that consist of alpha, beta, and gamma subunits that assemble
            through a coiled-coil domain. Laminins are essential for formation
            and function of the basement membrane and have additional functions
            in regulating cell migration and mechanical signal transduction.
            This gene encodes an alpha subunit and is responsive to several
            epithelial-mesenchymal regulators including keratinocyte growth
            factor, epidermal growth factor and insulin-like growth factor.
            Mutations in this gene have been identified as the cause of Herlitz
            type junctional epidermolysis bullosa and laryngoonychocutaneous
            syndrome. Alternative splicing and alternative promoter usage
            result in multiple transcript variants. [provided by RefSeq, Dec
            2014].
            
            Transcript Variant: This variant (1), also known as b1, represents
            the longest transcript and encodes the longest isoform (1, also
            known as alpha3B1). Variants 1 and 3 encode 'b' isoforms.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB107369.1, AY327115.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968189, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000313654.14/ ENSP00000324532.8
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-231               AC067796.11        125742-125972       c
            232-10233           AB107369.1         1-10002
            10234-10651         AC010754.10        63082-63499
FEATURES             Location/Qualifiers
     source          1..10651
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
                     /map="18q11.2"
     gene            1..10651
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="laminin subunit alpha 3"
                     /db_xref="GeneID:3909"
                     /db_xref="HGNC:HGNC:6483"
                     /db_xref="MIM:600805"
     exon            1..525
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     CDS             232..10233
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; laminin-5 alpha 3 chain; epiligrin 170 kda
                     subunit; epiligrin alpha 3 subunit; nicein 150kD subunit;
                     kalinin 165kD subunit; BM600 150kD subunit; laminin-5
                     subunit alpha; laminin-6 subunit alpha; laminin-7 subunit
                     alpha; nicein subunit alpha; kalinin subunit alpha;
                     laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600
                     (150kD), epilegrin); laminin A3; laminin 5, alpha-3
                     subunit; LAM3, alpha-3 subunit"
                     /codon_start=1
                     /product="laminin subunit alpha-3 isoform 1 precursor"
                     /protein_id="NP_937762.2"
                     /db_xref="CCDS:CCDS42419.1"
                     /db_xref="GeneID:3909"
                     /db_xref="HGNC:HGNC:6483"
                     /db_xref="MIM:600805"
                     /translation="MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAG
                     LSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFC
                     DYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKF
                     ANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEY
                     SRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKA
                     QRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCC
                     TGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCIN
                     CQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFH
                     GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGR
                     CLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRC
                     DRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKEN
                     PSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQ
                     GCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENNYYFPDLHHMKYEIEDGSTPN
                     GRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVILRYVNPGTEA
                     VSGHITIYPSWGAAQSKEIIFLPSKEPAFVTVPGNGFADPFSITPGIWVACIKAEGVL
                     LDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVTRFPCTLACEARHFL
                     LDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVEYSTEAAQLFVV
                     DVNVKSSGSVLAGQVNIYSCNYSVLCRSAVIDHMSRIAMYELLADADIQLKGHMARFL
                     LHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALILDVLSGRP
                     FPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPTFPAQVS
                     VDGGWPRAGSFHASFCPHVLGCRDQVIAEGQIEFDISEPEVAATVKVPEGKSLVLVRV
                     LVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYHKG
                     ALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE
                     EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQC
                     RCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECN
                     VCREGSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVS
                     FNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVSSYGGYLTYQAKSFGLPGDMVLL
                     EKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVL
                     SRLADVRIQGLYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGC
                     SPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA
                     VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSC
                     QPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRL
                     VKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQ
                     EFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEG
                     NNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGE
                     NNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEIN
                     SLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRS
                     AGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAE
                     DAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNL
                     QQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGL
                     NPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLG
                     NISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQR
                     PNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKS
                     ETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVF
                     YVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKE
                     ESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKL
                     MVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNTIIDGEVFDFS
                     TYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKCSEDWKLVRSA
                     SFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELS
                     TSDSGGPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISSSRQSLR
                     LGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRF
                     NKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFKLP
                     QELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALGTDGKKLRIKSK
                     EKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLGSPPSGKPKS
                     LPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLL
                     GPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPKQ
                     SLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLTTLR
                     IPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ"
     exon            526..678
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            679..796
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            797..915
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1086
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..1178
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1294
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1413
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..1504
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1636
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1699
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            1700..1834
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            1835..1972
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            1973..2019
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2119
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            2120..2172
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2278
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            2279..2378
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            2379..2535
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            2536..2659
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            2660..2802
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            2803..2900
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            2901..3054
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            3055..3215
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            3216..3324
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            3325..3422
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            3423..3567
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            3568..3694
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            3695..3834
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            3835..3950
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            3951..4162
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            4163..4367
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            4368..4512
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            4513..4653
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            4654..4815
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            4816..4914
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            4915..4998
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            4999..5229
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            5230..5343
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            5344..5453
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            5454..5534
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            5535..5641
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            5642..5692
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            5693..5844
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            5845..5955
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            5956..6067
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            6068..6235
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            6236..6432
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            6433..6549
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            6550..6704
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            6705..6846
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            6847..6949
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            6950..7066
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            7067..7246
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            7247..7389
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            7390..7560
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            7561..7712
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            7713..7875
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            7876..8009
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            8010..8154
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            8155..8274
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            8275..8408
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            8409..8526
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            8527..8667
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            8668..8807
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            8808..8939
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            8940..9093
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            9094..9257
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            9258..9441
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            9442..9582
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            9583..9742
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            9743..9873
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            9874..9967
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            9968..10087
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     exon            10088..10651
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10511..10516
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="hexamer: ATTAAA"
     regulatory      10525..10530
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="hexamer: AAGAAA"
     polyA_site      10530
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="major polyA site"
     regulatory      10555..10560
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="hexamer: ATTAAA"
     polyA_site      10555
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="major polyA site"
     regulatory      10559..10564
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="hexamer: AATATA"
     polyA_site      10574
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="major polyA site"
     polyA_site      10580
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
     regulatory      10625..10630
                     /regulatory_class="polyA_signal_sequence"
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="hexamer: ATTAAA"
     polyA_site      10651
                     /gene="LAMA3"
                     /gene_synonym="BM600; E170; JEB2A; JEB2B; JEB2C; LAMNA;
                     LOCS"
                     /note="major polyA site"
ORIGIN      
        1 agttcctgat ccggctggtg cccgctccag ccgcggcagg ttccagagct gagaggccac
       61 ccccacgccg cgggcttcca gcgcgtggag caaggggagc ggccccggcg ccgcccatat
      121 ccccggctgc gctagtcctg gcgctgcagg tccgggaggc gcaggcggag agcggcggtg
      181 cccccgagcc cctctgcgga cggctcaggc gggaggaccc cgcgcggctg gatggcggcg
      241 gccgcgcggc ctcggggtcg ggcactgggg ccagtactgc cgccgacgcc gctgctcctg
      301 ctggtactgc gggtgctgcc agcctgcggg gcgaccgctc gggatcccgg ggccgcggcc
      361 gggctcagcc ttcacccgac ttacttcaac ctggccgagg cggcgaggat ttgggccacc
      421 gccacctgcg gggagagggg acccggcgag gggaggcccc agcccgagct ctactgcaag
      481 ttggtcgggg gccccaccgc cccaggcagc ggccacacca tccagggcca gttctgtgac
      541 tattgcaatt ctgaagaccc caggaaagca catcctgtca ccaatgccat cgatggatct
      601 gaacgttggt ggcaaagccc tcccctgtcc tcaggcacac agtacaacag agtcaacctc
      661 accttggatc tggggcagct cttccatgtg gcctatattt taatcaaatt tgcaaattct
      721 cctcgccctg atctttgggt cttggaaaga tctgtagact ttggaagcac ctactcacca
      781 tggcaatatt ttgctcattc taaagtagac tgtttaaaag aatttgggcg ggaggcaaat
      841 atggctgtca cccgggatga tgatgtactt tgtgttactg aatattcccg tattgtacct
      901 ttggaaaatg gtgaggttgt ggtgtccttg ataaacggtc gtccaggtgc aaaaaatttt
      961 actttctctc acaccctgag ggagtttacc aaggcaacaa acatccgctt gcgttttctt
     1021 agaaccaata cgcttcttgg acacctcatc tccaaagccc agcgagatcc aactgtcact
     1081 cggcggtatt attacagcat aaaggacatc agcattggtg ggcagtgtgt ttgcaatggc
     1141 catgctgaag tgtgcaatat aaacaatcct gaaaaactgt ttcggtgtga atgccagcac
     1201 cacacctgtg gggagacgtg tgatcgctgc tgcacagggt acaatcagag gcgctggcgg
     1261 cccgccgctt gggagcagag ccacgagtgt gaagcatgca actgccacgg ccatgccagc
     1321 aactgttact atgatccaga tgttgagcgg cagcaggcaa gcttgaatac ccagggcatc
     1381 tatgctggtg gaggggtctg cattaactgt cagcacaaca cagctggagt aaactgtgaa
     1441 cagtgtgcta agggctatta ccgcccttat ggggttccag tggatgcccc tgatggctgc
     1501 atcccctgca gctgtgaccc tgagcatgcg gatggctgtg aacagggttc aggccgctgt
     1561 cactgcaagc caaatttcca cggagacaac tgtgagaagt gtgcaattgg atactacaat
     1621 ttcccatttt gcttgagaat tcccattttt cctgtttcta caccaagttc agaagatcca
     1681 gtagctggag atataaaagg gtgtgactgt aatctggaag gtgttctccc tgaaatatgt
     1741 gatgcccacg gacggtgcct gtgccgccct ggggttgagg gccctcgatg tgatacctgc
     1801 cgctctggtt tctactcatt ccctatttgc caagcctgct ggtgttcagc ccttggatcc
     1861 taccagatgc cctgcagctc agtgactgga cagtgtgaat gtcggccagg agttacagga
     1921 cagcggtgtg acaggtgtct ctcaggagct tatgatttcc cccactgcca aggttccagc
     1981 agtgcttgtg acccagctgg taccatcaac tccaatttgg ggtattgcca atgcaagctt
     2041 catgttgaag gtcctacttg tagccgctgc aaactgttat attggaatct ggacaaagaa
     2101 aaccccagtg gatgttcaga atgcaagtgc cataaggcgg gaacagtgag tggaactgga
     2161 gagtgtaggc agggagatgg tgactgtcac tgcaagtccc atgtgggtgg cgattcctgc
     2221 gacacctgtg aagatggata ttttgctttg gaaaagagca attactttgg gtgtcaaggg
     2281 tgtcagtgtg acattggtgg ggcattgtcc tccatgtgca gtgggccctc gggagtgtgc
     2341 cagtgccgag agcatgtcgt gggaaaggtg tgccagcggc ctgaaaacaa ctactatttc
     2401 ccagatttgc atcatatgaa gtatgagatt gaagacggca gcacacctaa tgggagagac
     2461 cttcgatttg gatttgatcc gctggcattt cctgagttta gctggagagg atatgcccaa
     2521 atgacctcag tacagaatga tgtaagaata acattgaatg tagggaagtc aagtggctcc
     2581 ttgtttcgtg ttattctgag atacgttaac cctggaactg aagcagtatc tggccatata
     2641 actatttatc catcctgggg tgctgctcaa agcaaagaga tcatcttcct gccgagtaag
     2701 gagccagcct ttgtcactgt ccctggaaat ggttttgcag acccattttc aatcacacca
     2761 ggaatatggg ttgcttgtat taaggcagaa ggagtccttc tggattacct ggtgctgctc
     2821 cccagggact actatgaagc ctctgtactg cagctgccag tcacagaacc atgtgcctac
     2881 gcaggacctc cccaagaaaa ttgcttactc taccagcatt tgccagtgac cagattcccc
     2941 tgtaccctgg cttgtgaggc cagacacttc ctgcttgatg gggagccaag acccgtggca
     3001 gtgaggcagc ccacacctgc acaccctgtc atggtggacc tcagcgggag agaggtggaa
     3061 ttgcatctgc ggctgcgcat cccacaggtt ggccactacg tggttgtggt cgagtattcc
     3121 acggaggcag ctcagctgtt tgtggttgat gtgaatgtga agagctccgg gtctgttctg
     3181 gcaggccagg tgaacattta cagctgcaac tacagtgttc tctgccggag tgctgtgatt
     3241 gatcacatga gccgcatcgc catgtatgag ctattggcag atgcagacat tcagctcaag
     3301 ggacacatgg cccgattcct tctgcatcaa gtttgtatca tacctattga agaattctca
     3361 gctgagtatg tgagaccaca agtccactgc attgccagtt atgggcgatt tgtcaatcaa
     3421 agtgccacct gtgtctcctt ggcccatgaa actcctccaa cagcattaat tttggatgtt
     3481 ctaagtggca ggcctttccc tcacctgccc cagcagtcgt caccttctgt tgatgttctt
     3541 cctggggtca ccttgaaggc accgcagaat caagtgaccc tgagaggacg tgtaccacac
     3601 ctgggccgat acgtctttgt catccatttt taccaagcag cgcacccgac gtttcccgcg
     3661 caggtgtcgg tggatggcgg gtggccacgg gcaggctcct tccatgcctc tttttgcccc
     3721 catgtgcttg gctgccggga tcaagtgatt gccgaaggcc agattgagtt tgacatctca
     3781 gagcctgaag tggccgcaac tgtgaaggtt ccagaaggaa agtccttggt tttggtccgt
     3841 gttctagtgg tgcctgcaga aaactatgac taccaaatac ttcacaaaaa atccatggac
     3901 aagtcactcg agtttatcac caattgtgga aaaaacagct tttaccttga cccccagaca
     3961 gcctccagat tctgtaagaa ttccgccagg tccctggtgg ccttttacca caagggcgcc
     4021 ctgccttgtg agtgccaccc cactggggcc accggccctc actgcagccc tgagggtggg
     4081 cagtgcccat gccagcccaa cgtcatcggg cggcagtgca cccgctgtgc aacaggccac
     4141 tacggattcc cacgctgcaa gccgtgcagc tgtggtcggc gcctttgtga agagatgacg
     4201 gggcagtgcc gctgccctcc ccgcacggtc aggccccagt gtgaggtgtg tgagacacac
     4261 tcattcagct tccaccccat ggccggctgc gaaggctgca actgttccag gaggggcacc
     4321 atcgaggctg ccatgccgga gtgtgaccgg gacagcgggc agtgcagatg caagcccaga
     4381 atcacagggc ggcagtgtga ccgatgtgct tccgggtttt accgctttcc tgagtgtgtt
     4441 ccctgcaatt gcaacagaga tgggactgag ccaggagtgt gtgacccagg gaccggggct
     4501 tgcctctgca aggaaaatgt agaaggcaca gagtgtaatg tgtgtcgaga aggctcattc
     4561 catttggacc cagccaatct caagggttgt accagctgtt tctgttttgg agtaaataat
     4621 caatgtcaca gctcacataa gcgaaggact aagtttgtgg atatgctggg ctggcacctg
     4681 gagacagcag acagagtgga catccctgtc tctttcaacc caggcagcaa cagtatggtg
     4741 gcggatctcc aggagctgcc cgcaaccatc cacagcgcgt cctgggtcgc acccacctcc
     4801 tacctggggg acaaggtttc ttcatatggt ggttacctca cttaccaagc caagtccttt
     4861 ggcttgcctg gcgacatggt tcttctggaa aagaagccgg atgtacagct cactggtcag
     4921 cacatgtcca tcatctatga ggagacaaac accccacggc cagaccggct gcatcatgga
     4981 cgagtgcacg tggtcgaggg aaacttcaga catgccagca gccgtgcccc agtgtctagg
     5041 gaggagctga tgacagtgct gtctagactg gcagatgtgc gcatccaagg cctctacttc
     5101 acagagactc aaaggctcac cctgagcgag gtggggctag aggaagcctc tgacacagga
     5161 agtgggcgca tagcacttgc tgtggaaatc tgtgcctgcc cccctgccta cgctggtgac
     5221 tcttgtcagg gttgtagccc tggatactat cgggatcata aaggcttgta taccggacgg
     5281 tgtgttccct gcaattgcaa cggacattca aatcaatgcc aggatggctc aggcatatgt
     5341 gttaactgtc agcacaacac cgcgggagag cactgtgaac gctgccagga gggctactat
     5401 ggcaacgccg tccacggatc ctgcagggcc tgcccatgtc ctcacactaa cagctttgcc
     5461 actggctgtg tggtgaatgg gggagacgtg cggtgctcct gcaaagctgg gtacacagga
     5521 acacagtgtg aaaggtgtgc accgggatat ttcgggaatc cccagaaatt cggaggtagc
     5581 tgccaaccat gcagttgtaa cagcaatggc cagctgggca gctgtcatcc cctgactgga
     5641 gactgcataa accaagaacc caaagatagc agccctgcag aagaatgtga tgattgcgac
     5701 agctgtgtga tgaccctcct gaacgacctg gccaccatgg gcgagcagct ccgcctggtc
     5761 aagtctcagc tgcagggcct gagtgccagc gcagggcttc tggagcagat gaggcacatg
     5821 gagacccagg ccaaggacct gaggaatcag ttgctcaact accgttctgc catttcaaat
     5881 catggatcaa aaatagaagg cctggaaaga gaactgactg atttgaatca agaatttgag
     5941 actttgcaag aaaaggctca agtaaattcc agaaaagcac aaacattaaa caacaatgtt
     6001 aatcgggcaa cacaaagcgc aaaagaactg gatgtgaaga ttaaaaatgt catccggaat
     6061 gtgcacattc ttttaaagca gatctctggg acagatggag agggaaacaa cgtgccttca
     6121 ggtgactttt ccagagagtg ggctgaagcc cagcgcatga tgagggaact gcggaacagg
     6181 aactttggaa agcacctcag agaagcagaa gctgataaaa gggagtcgca gctcttgctg
     6241 aaccggataa ggacctggca gaaaacccac cagggggaga acaatgggct tgctaacagt
     6301 atccgggatt ctttaaatga atacgaagcc aaactcagtg accttcgtgc tcggctgcag
     6361 gaggcagctg cccaagccaa gcaggcaaat ggcttgaacc aagaaaacga gagagctttg
     6421 ggagccattc agagacaagt gaaagaaata aattccctgc agagtgattt caccaagtat
     6481 ctaaccactg cagactcatc tttgttgcaa accaacattg cgctgcagct gatggagaaa
     6541 agccagaagg aatatgaaaa attagctgcc agtttaaatg aagcaagaca agaactaagt
     6601 gacaaagtaa gagaactttc cagatctgct ggcaaaacat cccttgtgga ggaggcagaa
     6661 aagcacgcgc ggtccttaca agagctggca aagcagctgg aagagatcaa gagaaacgcc
     6721 agcggggatg agctggtgcg ctgtgctgtg gatgccgcca ccgcctacga gaacatcctc
     6781 aatgccatca aagcggccga ggacgcagcc aacagggctg ccagtgcatc tgaatctgcc
     6841 ctccagacag tgataaagga agatctgcca agaaaagcta aaaccctgag ttccaacagt
     6901 gataaactgt taaatgaagc caagatgaca caaaagaagc taaagcaaga agtcagtcca
     6961 gctctcaaca acctacagca aaccctgaat attgtgacag ttcagaaaga agtgatagac
     7021 accaatctca caactctccg agatggtctt catgggatac agagaggtga tattgatgct
     7081 atgatcagta gtgcaaagag catggtcaga aaggccaacg acatcacaga tgaggttctg
     7141 gatgggctca accccatcca gacagatgtg gaaagaatta aggacaccta tgggaggaca
     7201 cagaacgaag acttcaaaaa ggctctgact gatgcagata actcggtgaa taagttaacc
     7261 aacaaactac ctgatctttg gcgcaagatt gaaagtatca accaacagct gttgcccttg
     7321 ggaaacatct ctgacaacat ggacagaata cgagaactaa ttcagcaggc cagagatgct
     7381 gccagtaagg ttgctgtccc catgaggttc aatggtaaat ctggagtcga agtccgactg
     7441 ccaaatgacc tggaagattt gaaaggatat acatctctgt ccttgtttct ccaaaggccc
     7501 aactcaagag aaaatggggg tactgagaat atgtttgtga tgtaccttgg aaataaagat
     7561 gcctcccggg actacatcgg catggcagtt gtggatggcc agctcacctg tgtctacaac
     7621 ctgggggacc gtgaggctga actccaagtg gaccagatct tgaccaagag tgagactaag
     7681 gaggcagtta tggatcgggt gaaatttcag agaatttatc agtttgcaag gcttaattac
     7741 accaaaggag ccacatccag taaaccagaa acacccggag tctatgacat ggatggtaga
     7801 aatagcaata cactccttaa tttggatcct gaaaatgttg tattttatgt tggaggttac
     7861 ccacctgatt ttaaacttcc cagtcgacta agtttccctc catacaaagg ttgtattgaa
     7921 ttagatgacc tcaatgaaaa tgttctgagc ttgtacaact tcaaaaaaac attcaatctc
     7981 aacacaactg aagtggagcc ttgtagaagg aggaaggaag agtcagacaa aaattatttt
     8041 gaaggtacgg gctatgctcg agttccaact caaccacatg ctcccatccc aacctttgga
     8101 cagacaattc agaccaccgt ggatagaggc ttgctgttct ttgcagaaaa cggggatcgc
     8161 ttcatatctc taaatataga agatggcaag ctcatggtga gatacaaact gaattcagag
     8221 ctaccaaaag agagaggagt tggagacgcc ataaacaacg gcagagacca ttcgattcag
     8281 atcaaaattg gaaaactcca aaagcgtatg tggataaatg tggacgttca aaacactata
     8341 attgatggtg aagtatttga tttcagcaca tattatctgg gaggaattcc aattgcaatc
     8401 agggaaagat ttaacatttc tacgcctgct ttccgaggct gcatgaaaaa tttgaagaaa
     8461 accagtggtg tcgttagatt gaatgatact gtgggagtaa ccaaaaagtg ctcggaagac
     8521 tggaagcttg tgcgatctgc ctcattctcc agaggaggac aattgagttt cactgatttg
     8581 ggcttaccac ctactgacca cctccaggcc tcatttggat ttcagacctt tcaacccagt
     8641 ggcatattat tagatcatca gacatggaca aggaacctgc aggtcactct ggaagatggt
     8701 tacattgaat tgagcaccag cgatagcggc ggcccaattt ttaaatctcc acagacgtat
     8761 atggatggtt tactgcatta tgtatctgta ataagcgaca actctggact acggcttctc
     8821 atcgatgacc agcttctgag aaatagcaaa aggctaaaac acatttcaag ttcccggcag
     8881 tctctgcgtc tgggcgggag caattttgag ggttgtatta gcaatgtttt tgtccagagg
     8941 ttatcactga gtcctgaagt cctagatttg accagtaact ctctcaagag agatgtgtcc
     9001 ctgggaggct gcagtttaaa caaaccacct tttctaatgt tgcttaaagg ttctaccagg
     9061 tttaacaaga ccaagacttt tcgtatcaac cagctgttgc aggacacacc agtggcctcc
     9121 ccaaggagcg tgaaggtgtg gcaagatgct tgctcaccac ttcccaagac ccaggccaat
     9181 catggagccc tccagtttgg ggacattccc accagccact tgctattcaa gcttcctcag
     9241 gagctgctga aacccaggtc acagtttgct gtggacatgc agacaacatc ctccagagga
     9301 ctggtgtttc acacgggcac taagaactcc tttatggctc tttatctttc aaaaggacgt
     9361 ctggtctttg cactggggac agatgggaaa aaattgagga tcaaaagcaa ggagaaatgc
     9421 aatgatggga aatggcacac ggtggtgttt ggccatgatg gggaaaaggg gcgcttggtt
     9481 gtggatggac tgagggcccg ggagggaagt ttgcctggaa actccaccat cagcatcaga
     9541 gcgccagttt acctgggatc acctccatca gggaaaccaa agagcctccc cacaaacagc
     9601 tttgtgggat gcctgaagaa ctttcagctg gattcaaaac ccttgtatac cccttcttca
     9661 agcttcgggg tgtcttcctg cttgggtggt cctttggaga aaggcattta tttctctgaa
     9721 gaaggaggtc atgtcgtctt ggctcactct gtattgttgg ggccagaatt taagcttgtt
     9781 ttcagcatcc gcccaagaag tctcactggg atcctaatac acatcggaag tcagcccggg
     9841 aagcacttat gtgtttacct ggaggcagga aaggtcacgg cctctatgga cagtggggca
     9901 ggtgggacct caacgtcggt cacaccaaag cagtctctgt gtgatggaca gtggcactcg
     9961 gtggcagtca ccataaaaca acacatcctg cacctggaac tggacacaga cagtagctac
    10021 acagctggac agatcccctt cccacctgcc agcactcaag agccactaca ccttggaggt
    10081 gctccagcca atttgacgac actgaggatc cctgtgtgga aatcattctt tggctgtctg
    10141 aggaatattc atgtcaatca catccctgtc cctgtcactg aagccttgga agtccagggg
    10201 cctgtcagtc tgaatggttg tcctgaccag taacccaagc ctatttcaca gcaaggaaat
    10261 tcaccttcaa aagcactgat tacccaatgc acctccctcc ccagctcgag atcattcttc
    10321 actcaggaca caaaccagac aggtttaata gcgaatctaa ttttgaattc tgaccatgga
    10381 tacccatcac tttggcattc agtgctacat gtgtatttta tataaaaatc ccatttcttg
    10441 aagataaaaa aattgttatt caaattgtta tgcacagaat gtttttggta atattaattt
    10501 ccactaaaaa attaaatgtc ttttaagaaa cattcttttc cacttgttaa aaaaattaaa
    10561 tatattttaa agcactttaa gaatatgaaa ctttcatata tgttaaagga ttataattta
    10621 tggaattaaa aaatgcagtg tagtccttaa a
//
