LOCUS       NM_001289974            1950 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens lactamase beta like 1 (LACTBL1), mRNA.
ACCESSION   NM_001289974
VERSION     NM_001289974.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1950)
  AUTHORS   Gregory,S.G., Barlow,K.F., McLay,K.E., Kaul,R., Swarbreck,D.,
            Dunham,A., Scott,C.E., Howe,K.L., Woodfine,K., Spencer,C.C.,
            Jones,M.C., Gillson,C., Searle,S., Zhou,Y., Kokocinski,F.,
            McDonald,L., Evans,R., Phillips,K., Atkinson,A., Cooper,R.,
            Jones,C., Hall,R.E., Andrews,T.D., Lloyd,C., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Anderson,F., Andrew,R.W., Ashwell,R.I.,
            Aubin,K., Babbage,A.K., Bagguley,C.L., Bailey,J., Beasley,H.,
            Bethel,G., Bird,C.P., Bray-Allen,S., Brown,J.Y., Brown,A.J.,
            Buckley,D., Burton,J., Bye,J., Carder,C., Chapman,J.C., Clark,S.Y.,
            Clarke,G., Clee,C., Cobley,V., Collier,R.E., Corby,N.,
            Coville,G.J., Davies,J., Deadman,R., Dunn,M., Earthrowl,M.,
            Ellington,A.G., Errington,H., Frankish,A., Frankland,J., French,L.,
            Garner,P., Garnett,J., Gay,L., Ghori,M.R., Gibson,R., Gilby,L.M.,
            Gillett,W., Glithero,R.J., Grafham,D.V., Griffiths,C.,
            Griffiths-Jones,S., Grocock,R., Hammond,S., Harrison,E.S., Hart,E.,
            Haugen,E., Heath,P.D., Holmes,S., Holt,K., Howden,P.J., Hunt,A.R.,
            Hunt,S.E., Hunter,G., Isherwood,J., James,R., Johnson,C.,
            Johnson,D., Joy,A., Kay,M., Kershaw,J.K., Kibukawa,M.,
            Kimberley,A.M., King,A., Knights,A.J., Lad,H., Laird,G., Lawlor,S.,
            Leongamornlert,D.A., Lloyd,D.M., Loveland,J., Lovell,J., Lush,M.J.,
            Lyne,R., Martin,S., Mashreghi-Mohammadi,M., Matthews,L.,
            Matthews,N.S., McLaren,S., Milne,S., Mistry,S., Moore,M.J.,
            Nickerson,T., O'Dell,C.N., Oliver,K., Palmeiri,A., Palmer,S.A.,
            Parker,A., Patel,D., Pearce,A.V., Peck,A.I., Pelan,S., Phelps,K.,
            Phillimore,B.J., Plumb,R., Rajan,J., Raymond,C., Rouse,G.,
            Saenphimmachak,C., Sehra,H.K., Sheridan,E., Shownkeen,R., Sims,S.,
            Skuce,C.D., Smith,M., Steward,C., Subramanian,S., Sycamore,N.,
            Tracey,A., Tromans,A., Van Helmond,Z., Wall,M., Wallis,J.M.,
            White,S., Whitehead,S.L., Wilkinson,J.E., Willey,D.L., Williams,H.,
            Wilming,L., Wray,P.W., Wu,Z., Coulson,A., Vaudin,M., Sulston,J.E.,
            Durbin,R., Hubbard,T., Wooster,R., Dunham,I., Carter,N.P.,
            McVean,G., Ross,M.T., Harrow,J., Olson,M.V., Beck,S., Rogers,J.,
            Bentley,D.R., Banerjee,R., Bryant,S.P., Burford,D.C., Burrill,W.D.,
            Clegg,S.M., Dhami,P., Dovey,O., Faulkner,L.M., Gribble,S.M.,
            Langford,C.F., Pandian,R.D., Porter,K.M. and Prigmore,E.
  TITLE     The DNA sequence and biological annotation of human chromosome 1
  JOURNAL   Nature 441 (7091), 315-321 (2006)
   PUBMED   16710414
  REMARK    Erratum:[Nature. 2006 Oct 26;443(7114):1013. Banerjee, R [added];
            Bryant, SP [added]; Burford, DC [added]; Burrill, WDH [added];
            Clegg, SM [added]; Dhami, P [added]; Dovey, O [added]; Faulkner, LM
            [added]; Gribble, SM [added]; Langford, CF [added]; Pandian, RD
            [added]; Porter, KM [added]; Prigmore, E]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035704.9.
            
            On Aug 29, 2018 this sequence version replaced NM_001289974.1.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000426928.7/ ENSP00000402297.3
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 5' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                AL035704.9         92659-92753         c
            96-222              AL035704.9         92192-92318         c
            223-358             AL035704.9         85177-85312         c
            359-468             AL035704.9         82994-83103         c
            469-626             AL035704.9         79829-79986         c
            627-862             AL035704.9         78572-78807         c
            863-968             AL035704.9         75208-75313         c
            969-1950            AL035704.9         72930-73911         c
FEATURES             Location/Qualifiers
     source          1..1950
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.12"
     gene            1..1950
                     /gene="LACTBL1"
                     /note="lactamase beta like 1"
                     /db_xref="GeneID:646262"
                     /db_xref="HGNC:HGNC:35445"
     exon            1..95
                     /gene="LACTBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            96..222
                     /gene="LACTBL1"
                     /inference="alignment:Splign:2.1.0"
     CDS             211..1950
                     /gene="LACTBL1"
                     /codon_start=1
                     /product="putative beta-lactamase-like 1"
                     /protein_id="NP_001276903.1"
                     /db_xref="CCDS:CCDS90879.1"
                     /db_xref="GeneID:646262"
                     /db_xref="HGNC:HGNC:35445"
                     /translation="MKTQDGWWPNLLKVKKKWLLPAICSFFCLLSVVMTGCFLWQYHL
                     PKLKTGSLGPEETSAPVRMCPRHPEPVPLAHPLPVLKEALEKVDQILRQAMSAPGVAA
                     MSAVVIHNDTVLWTGNFGKKNGSDPASGAPNEYTMYRISSISKIFPVLMLYRLWEEGI
                     VASLDDPLERYASTFTINNPLGLASAEQQGLMDGLEQVGPAPRPSPVTLRRMASQLSG
                     LPRRLRSTSLLWKGSTQEALNLLKDDVLVVDPGTRCHYSTLAFSLLAHVLAAHTAQGD
                     YQRWVSENVLEPLGMADTGFDLTPDVRARLAAGFYGSGRPAPLYDLGWYRPSGQMYST
                     AADLAKLAVALLGGGPRRLLRPDAAKTLLAPLLACPGAYFANETGTPWEFHAQRGYRV
                     VRKDGDLDGYAATFSLVPPLRLGLVLLLAGPRPPGPDLVARAYDELLPALERALREAE
                     PGPAPPPTAHPFAGYFTFANLTFYEVRAGPAGELRLRQFGPRVEALVPPAFRTLALRH
                     LHGRVFQLHVAHEFPCALPLGDAWLSLEAQHGQLVNFYPLDHHGLSPGFDVPGLNTYR
                     VLRLRGKPVFKTQ"
     exon            223..358
                     /gene="LACTBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            359..468
                     /gene="LACTBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            469..626
                     /gene="LACTBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            627..862
                     /gene="LACTBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            863..968
                     /gene="LACTBL1"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1950
                     /gene="LACTBL1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attcctgtcc tctggaacac aggggactcc cagaggcact gtcagccaaa ctggggccct
       61 aactgccctg ttcttgctgg taccttctgg agaggcccct caggacctct ttttgccttc
      121 actcctctga ctcagtttcc tgcttacggg atctcctgtg gtgtagacct gaatcctcaa
      181 agagccagaa tcttccatgc cttggagaga atgaagaccc aggatggctg gtggcccaac
      241 ttgctgaaag tgaagaagaa gtggctcctc ccggccatct gcagcttctt ctgcctgctc
      301 tcagtggtca tgactggctg cttcctgtgg cagtatcacc tccccaagct gaagaccggt
      361 tccctgggac cagaggagac ctctgcccct gtgaggatgt gtccccggca ccctgagccc
      421 gtgcccctgg ctcacccact ccccgtgttg aaggaggccc tggaaaaggt ggaccagatc
      481 ctgcgccagg caatgtctgc cccaggcgtg gctgccatgt ctgcagttgt catccacaat
      541 gatactgtgc tctggacagg gaactttggg aagaagaatg gctcagaccc ggcttctggg
      601 gcccccaatg agtacaccat gtacaggatc tccagcatct ccaagatctt tcctgtcctc
      661 atgctgtacc gtctgtggga ggagggcatc gtggcctccc tagatgaccc tctggagcgg
      721 tatgccagca ccttcaccat taacaacccg ctgggcctgg catcagccga acagcagggc
      781 ctgatggacg ggctggagca ggtgggcccc gccccaaggc cttcacctgt cacccttcga
      841 aggatggcca gccagctctc agggctgccc agaaggctgc gctccacttc actgctgtgg
      901 aagggcagca cccaggaggc cctgaacctg ctcaaggacg atgtgctggt agtggacccg
      961 ggaaccagat gccattacag cacgctggcc ttctcgctcc tggcccacgt cctggcagct
     1021 cacaccgccc agggcgacta ccagcgctgg gtctcggaga acgtgctgga gccgctgggg
     1081 atggcagaca cgggctttga cctcacgccc gacgtgcgcg cgcgcctggc cgcgggcttc
     1141 tacggcagcg ggcggccggc gccactctat gacctgggct ggtaccggcc gtcgggccag
     1201 atgtactcta ccgccgccga cctggccaag ctggccgtgg cgctcctggg cggcgggccc
     1261 cggcggctcc tgcggcccga cgcggccaag acgctgctgg cgccgctgct ggcctgcccg
     1321 ggcgcctact tcgccaacga gacgggcacg ccgtgggagt tccacgcgca gcggggctac
     1381 cgcgtggtgc gcaaggacgg cgatctggac ggctacgccg ccaccttctc gctggtgccc
     1441 ccgctgcgtc tgggcctggt gctgctgctg gcagggccac ggccgcccgg gcccgacctg
     1501 gtggcgcggg cctacgatga gctcctgccc gccctggagc gcgccctccg ggaggccgag
     1561 cccggcccgg ctccgccgcc caccgcgcac cccttcgccg gctacttcac cttcgccaac
     1621 ctgaccttct acgaggtgcg cgccgggccg gcgggcgagc tgcgcctgcg ccagttcggg
     1681 ccgcgcgtgg aggcgctggt gcctccagcg ttccgcaccc tggcgctgcg ccacctgcac
     1741 ggccgcgtct tccagctgca cgtggcccac gagttcccct gcgcactgcc actcggcgac
     1801 gcgtggctct cgctcgaggc ccagcacggg cagctggtca acttctaccc cttggatcac
     1861 cacgggctgt cacccggctt cgacgtgccc ggcctcaaca cgtacagagt gctgcggctg
     1921 cggggcaagc cggtgttcaa gacccagtga
//
