LOCUS       NM_001414398            5646 bp    mRNA    linear   PRI 17-JUL-2023
DEFINITION  Homo sapiens KYAT1-SPOUT1 readthrough (KYAT1-SPOUT1), transcript
            variant 1, mRNA.
ACCESSION   NM_001414398
VERSION     NM_001414398.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL672142.9 and AL441992.17.
            
            Summary: This locus represents naturally occurring readthrough
            transcription between the neighboring KYAT1 (kynurenine
            aminotransferase 1) and SPOUT1 (SPOUT domain containing
            methyltransferase 1) genes on chromosome 9. The readthrough
            transcript encodes a fusion protein that shares sequence identity
            with each individual gene product. [provided by RefSeq, Nov 2022].
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 883, 51490
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                AL672142.9         17825-17872         c
            49-107              AL441992.17        145939-145997       c
            108-255             AL441992.17        143240-143387       c
            256-405             AL441992.17        138804-138953       c
            406-492             AL441992.17        138637-138723       c
            493-621             AL441992.17        138271-138399       c
            622-742             AL441992.17        137388-137508       c
            743-819             AL441992.17        136583-136659       c
            820-909             AL441992.17        136365-136454       c
            910-1096            AL441992.17        136067-136253       c
            1097-1176           AL441992.17        135909-135988       c
            1177-1437           AL441992.17        130331-130591       c
            1438-1483           AL441992.17        129696-129741       c
            1484-1609           AL441992.17        129321-129446       c
            1610-1769           AL441992.17        127618-127777       c
            1770-1859           AL441992.17        127126-127215       c
            1860-1909           AL441992.17        126970-127019       c
            1910-2040           AL441992.17        126608-126738       c
            2041-2113           AL441992.17        125563-125635       c
            2114-2212           AL441992.17        125357-125455       c
            2213-2315           AL441992.17        124658-124760       c
            2316-2463           AL441992.17        124333-124480       c
            2464-5646           AL441992.17        120237-123419       c
FEATURES             Location/Qualifiers
     source          1..5646
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.11"
     gene            1..5646
                     /gene="KYAT1-SPOUT1"
                     /note="KYAT1-SPOUT1 readthrough"
                     /db_xref="GeneID:127739546"
     exon            1..48
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            49..107
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..2532
                     /gene="KYAT1-SPOUT1"
                     /codon_start=1
                     /product="uncharacterized protein LOC127739546"
                     /protein_id="NP_001401327.1"
                     /db_xref="GeneID:127739546"
                     /translation="MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPD
                     FAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYG
                     ALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW
                     QLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQW
                     MVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNS
                     VFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIP
                     QGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKRGAPSHPKFSTVPAMPPI
                     WTPTLPNLLQPAYPCSPSGAQATPLGDIGSPIGQLNGGVAGRGESHWQRRDRRCVRNM
                     AERGRKRPCGPGEHGQRIEWRKWKQQKKEEKKKWKDLKLMKKLERQRAQEEQAKRLEE
                     EEAAAEKEDRGRPYTLSVALPGSILDNAQSPELRTYLAGQIARACAIFCVDEIVVFDE
                     EGQDAKTVEGEFTGVGKKGQACVQLARILQYLECPQYLRKAFFPKHQDLQFAGLLNPL
                     DSPHHMRQDEESEFREGIVVDRPTRPGHGSFVNCGMKKEVKIDKNLEPGLRVTVRLNQ
                     QQHPDCKTYHGKVVSSQDPRTKAGLYWGYTVRLASCLSAVFAEAPFQDGYDLTIGTSE
                     RGSDVASAQLPNFRHALVVFGGLQGLEAGADADPNLEVAEPSVLFDLYVNTCPGQGSR
                     TIRTEEAILISLAALQPGLIQAGARHT"
     exon            108..255
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            256..405
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            406..492
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            493..621
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            622..742
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            743..819
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            820..909
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            910..1096
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1176
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1437
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1483
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1609
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1769
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1859
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..1909
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            1910..2040
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2113
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2212
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2315
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2316..2463
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     exon            2464..5646
                     /gene="KYAT1-SPOUT1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3208..3213
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KYAT1-SPOUT1"
                     /note="hexamer: AATAAA"
     polyA_site      3227
                     /gene="KYAT1-SPOUT1"
                     /note="major polyA site"
     regulatory      5625..5630
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KYAT1-SPOUT1"
                     /note="hexamer: AATAAA"
     polyA_site      5646
                     /gene="KYAT1-SPOUT1"
ORIGIN      
        1 gctgcaacct acggggtgta cttgggaacg aggggtgaag cggcccagct cgccatggcc
       61 aaacagctgc aggcccgaag gctagacggg atcgactaca acccctgggt ggagtttgtg
      121 aaactggcca gtgagcatga cgtcgtgaac ttgggccagg gcttcccgga tttcccacca
      181 ccagactttg ccgtggaagc ctttcagcac gctgtcagtg gagacttcat gcttaaccag
      241 tacaccaaga catttggtta cccaccactg acgaagatcc tggcaagttt ctttggggag
      301 ctgctgggtc aggagataga cccgctcagg aatgtgctgg tgactgttgg tggctatggg
      361 gccctgttca cagccttcca ggccctggtg gacgaaggag acgaggtcat catcatcgaa
      421 cccttttttg actgctacga gcccatgaca atgatggcag ggggtcgtcc tgtgtttgtg
      481 tccctgaagc cgggtcccat ccagaatgga gaactgggtt ccagcagcaa ctggcagctg
      541 gaccccatgg agctggccgg caaattcaca tcacgcacca aagccctggt cctcaacacc
      601 cccaacaacc ccctgggcaa ggtgttctcc agggaagagc tggagctggt ggccagcctt
      661 tgccagcagc atgacgtggt gtgtatcact gatgaagtct accagtggat ggtctacgac
      721 gggcaccagc acatcagcat tgccagcctc cctggcatgt gggaacggac cctgaccatc
      781 ggcagcgccg gcaagacctt cagcgccact ggctggaagg tgggctgggt cctgggtcca
      841 gatcacatca tgaagcacct gcggaccgtg caccagaact ccgtcttcca ctgccccacg
      901 cagagccagg ctgcagtagc cgagagcttt gaacgggagc agctgctctt ccgccaaccc
      961 agcagctact ttgtgcagtt cccgcaggcc atgcagcgct gccgtgacca catgatacgt
     1021 agcctacagt cagtgggcct gaagcccatc atccctcagg gcagctactt cctcatcaca
     1081 gacatctcag acttcaagag gaagatgcct gacttgcctg gagctgtgga tgagccctat
     1141 gacagacgct tcgtcaagtg gatgatcaag aacaagaggg gggctccgag ccatccaaaa
     1201 ttcagcacag tacccgcgat gccgcctatt tggacaccta ctctgcccaa cctactccag
     1261 cccgcgtacc cctgcagccc gtcgggcgcc caggccacgc ccctgggcga tattggctct
     1321 ccgattggac agcttaatgg aggtgtggcc ggaagaggcg agtctcattg gcagaggcgg
     1381 gaccgacggt gtgtgcggaa catggcggag cgcggcagga agcggccgtg cggcccgggt
     1441 gaacacggcc aaaggattga gtggcgaaaa tggaagcaac agaagaaaga ggagaaaaaa
     1501 aaatggaagg atctcaagct gatgaaaaaa ctggagcggc agcgggcaca ggaggaacag
     1561 gcaaagcgcc tggaagagga ggaggcagcg gcagagaagg aggaccgcgg gcggccctac
     1621 acactgagcg tagccctgcc gggctccatc ctggacaatg ctcagtcgcc ggagcttcgc
     1681 acctacttgg ccggtcagat tgccagagcc tgtgccatct tctgtgtgga tgagatcgtg
     1741 gtgtttgatg aggagggcca ggatgccaag actgtggagg gggaattcac aggagttggg
     1801 aagaaggggc aggcgtgcgt acagctggcc cggatcctgc agtacctgga gtgtccacag
     1861 tacctgagga aggcgttctt ccccaagcac caggatctac agtttgcagg gctcctgaac
     1921 cccctggaca gcccccacca catgcgtcag gatgaggaat ccgagttccg agagggcatc
     1981 gtggtggatc ggcccacccg gccaggccac ggctcctttg tcaactgtgg catgaaaaag
     2041 gaggtgaaga ttgacaagaa cctggagccc gggcttcggg tgactgtgcg actgaaccag
     2101 cagcagcacc cagactgcaa gacctaccat ggcaaagtgg tatcatcgca ggaccctcgc
     2161 accaaagctg gtctctactg gggctacacc gtccgactgg cttcctgcct cagtgctgtg
     2221 tttgctgagg cccccttcca agatgggtat gacctgacca tcgggacgtc agagcgcggc
     2281 tcagatgtgg cctctgccca gcttcccaac ttcaggcatg ctcttgtggt gttcgggggc
     2341 ctccagggtc tggaagctgg agcggatgct gaccccaacc tggaggtggc tgaacccagt
     2401 gtcctctttg acctgtacgt caatacctgt cctggccagg gtagccgtac catccgcacg
     2461 gaggaagcca tcctcatctc cctggccgcc ctgcagcctg gcctcatcca ggcgggtgcc
     2521 cggcacacct gaaagttcta aggggccgag gacatcagtg aagcagcagt gaaaccaggg
     2581 gctctgcagg tcacttggga cggacgccac cagacttgtc tccaaaaatc accaccttta
     2641 atactccccg gcctgcacac acccacagtc tcactgggct ccaccctcac ttactgcccg
     2701 ccgtgatggc cttgaggctg cctgcccgcg ccaggatgtt tggcacaaag agcagccccg
     2761 aagcccgctc aatgctctcg atgggcacca ggaagcgctc cagtgggatg gcctcatcca
     2821 caggtgcgtt gggcatcacg taggtgcgga gctcaatttg cccacctgct gcctccagga
     2881 tcagcacctt gaagaagtgt gtgggcactg ccacgtggtt cttgccgatg acctggtact
     2941 ttacgtagga tttcccatca gcctctgtcc tgtgggcaga cccaggcaca cgtgggcagg
     3001 gggcctggat gaacccaaag ccacctcttc caggcagcct tccctgatct gtcctctaac
     3061 ttctgtcaac ctgcaggacc acgccctcac tgtgagactt ctgtagcctg cctggctcct
     3121 ccttgaggct ggaactctct ccagggtggt taactctttc cctctgtttt ccttatgccc
     3181 aacactgggt caggcagagt gggcgacaat aaacgctgct aggagaatcg agccttctga
     3241 atattcacat tcgtctgagg ggagacttaa cgactgtcca tctctcccca cagaggtgag
     3301 caacaagtgg gcaaggacca tgacaggtga tatcccagca ccagcacagg tgccaggaca
     3361 ccggacgggg gctccccctc agcagagtct cctcccttcc accaggccct aggaggcacc
     3421 tgctaatgaa atttgatcag tgccccaacc accgccttgg ccagcctatg ccgagccctt
     3481 accatggacc aggccctggg gaagcatgtg acatcaacca agaggtcaca ggttttgcag
     3541 agggggacac aggtcatttg cccacagcac caaggaacta ggtgatgagg cctggactcc
     3601 atcccgagcc tgtggattcc agagtgagct gctcagcctg gacctgttgc ctctcagccc
     3661 cagccctctg caggccagaa aaaccacgga gcacacccag aggtgctcag ttgcttccac
     3721 ctgagaggca gggctgcaca ggagcaagag tggaggccct gggtcaggca gatctagatt
     3781 caaactcccg agaagggtgg agggaagtgc tccaagcaga gcagagactg aaggcgggag
     3841 agcctggtgc accgcggacc tgcaggggga aggcatgaga gctcggtgca ctggggacct
     3901 gcatggggaa ggcgggagag ctcggtgcac tggggacctg catggggaag gcgtgagagc
     3961 tcggtgcact ggggacctgc atggggaagg cgggagagct cggtgcacct cggacctgca
     4021 gagggaaggt gggagagctt ggtgcaccgc agacctgcag ggggaaggcg ggagagcttg
     4081 gtgcactgca gacctgcggg gggaaggtgg gagagcttgg tgcactgcag acctgcgggg
     4141 ggttccatat tggcagaaca agattgggtg ggcatgccaa gaggtgacag cagggagaag
     4201 cgggggcaga ttcagggcct gctgctgccc atgggcagag gagagatggt caggggtacc
     4261 cgacaggtct ttggctgtgg aggtggaatg aggggactcg aggcagggaa gctgacaggc
     4321 ttgccaagaa accagatgag tagggaactg gtattgaccc agagcctggg gcaagcctgg
     4381 ccctgtgagt ggcagtaggg gcctcaggtg agtgggaggt tctgccgccc ccctggtttc
     4441 caccttacct gggcaggaag agtggccctg tgcagacata gacgttttgg tagctgcggg
     4501 tcaagctgcg gctatatttc tccaggttgt tccaggcatt ctggttgagg tggggcacct
     4561 ggtaggagag atagggctta gcaggactgt ggctgggacc cttcctcctc tatcagaggg
     4621 ccgccccagg tcctgagggg atggacaggc tcagagatat ccagtgagac aagcgggggg
     4681 aaactgaggc tcaaggaatg aaagtcactc cctgaaaccc agggctgata gagtgctagc
     4741 caccaccctc tgtccctccc acagcccagg tgtcaaagtc ttttctcagc tcccaagagt
     4801 cgaatgaagg aagagcctgt ctccaccttt cagagaggac tgaggcctgt ccccagcccc
     4861 acccagggtc tcctgggaag accagccctt ccaactacca acccgttcct tttcccagtc
     4921 tgagccacag gaagagccta gcggggaatg ccatgaatcg acctccatcc tgagctctcc
     4981 aggcctggga caatggaaag tggatagggg gctgtcttcc cagaaggaag ctgggtcaga
     5041 ggttggtgcc ccatgggctc cacccagagc cccatggcag tctccatcca ttggtgccag
     5101 gacctgctgg gaacaggctg agagggtggt tggcccagtg cacagtgcct ggcactaaca
     5161 acctgatcgt gggccaggtg tctgcctcga aactgcctga aggcaggcag ggtaggacaa
     5221 tgtctggagg ctcacggttt tatagactag gggtccccaa cccctgggct acagaccggt
     5281 accagaaccg ggccacacag caggaggtga gcagcaggcg agcaagggaa gcttcatctg
     5341 tatttacagc caccccccca ttgatcccac agcagcctga gctccgcctc ctgtcagatc
     5401 agtggcggct ggagattgtc ataggagctg gaaccctatg gtgaactgcg catgtgagga
     5461 ggttgcgcgc ttcttttgaa aacctaatgc ctgatctgtc gttgttgccc atcacctcca
     5521 gataggactg tctagttgca ggaaaacaag ctcagggctc ccacggatcc tacattactg
     5581 tgagttgtat atttcactat atgttacaat gtaataataa tagaaataaa atgtacataa
     5641 atgtaa
//
