LOCUS       NM_138417               1708 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens KTI12 chromatin associated homolog (KTI12), mRNA.
ACCESSION   NM_138417
VERSION     NM_138417.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1708)
  AUTHORS   Smejda,M., Kadziolka,D., Radczuk,N., Krutyholowa,R.,
            Chramiec-Glabik,A., Kedracka-Krok,S., Jankowska,U., Biela,A. and
            Glatt,S.
  TITLE     Same but different - Molecular comparison of human KTI12 and PSTK
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1868 (4), 118945 (2021)
   PUBMED   33417976
  REMARK    GeneRIF: Same but different - Molecular comparison of human KTI12
            and PSTK.
REFERENCE   2  (bases 1 to 1708)
  AUTHORS   Fichtner,L., Frohloff,F., Burkner,K., Larsen,M., Breunig,K.D. and
            Schaffrath,R.
  TITLE     Molecular analysis of KTI12/TOT4, a Saccharomyces cerevisiae gene
            required for Kluyveromyces lactis zymocin action
  JOURNAL   Mol Microbiol 43 (3), 783-791 (2002)
   PUBMED   11929532
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL445685.18, BI909162.1, BC012173.1 and AF327348.1.
            
            On May 17, 2019 this sequence version replaced NM_138417.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR3476690.1014987.1,
                                        SRR1163657.501614.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000371614.2/ ENSP00000360676.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AL445685.18        100490-100499       c
            11-730              BI909162.1         17-736
            731-1704            BC012173.1         685-1658
            1705-1706           AF327348.1         1676-1677
            1707-1708           AL445685.18        98792-98793         c
FEATURES             Location/Qualifiers
     source          1..1708
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p32.3"
     gene            1..1708
                     /gene="KTI12"
                     /gene_synonym="SBBI81; TOT4"
                     /note="KTI12 chromatin associated homolog"
                     /db_xref="GeneID:112970"
                     /db_xref="HGNC:HGNC:25160"
     exon            1..1708
                     /gene="KTI12"
                     /gene_synonym="SBBI81; TOT4"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1114
                     /gene="KTI12"
                     /gene_synonym="SBBI81; TOT4"
                     /note="KTI12 homolog, chromatin associated"
                     /codon_start=1
                     /product="protein KTI12 homolog"
                     /protein_id="NP_612426.1"
                     /db_xref="CCDS:CCDS562.1"
                     /db_xref="GeneID:112970"
                     /db_xref="HGNC:HGNC:25160"
                     /translation="MPLVVFCGLPYSGKSRRAEELRVALAAEGRAVYVVDDAAVLGAE
                     DPAVYGDSAREKALRGALRASVERRLSRHDVVILDSLNYIKGFRYELYCLARAARTPL
                     CLVYCVRPGGPIAGPQVAGANENPGRNVSVSWRPRAEEDGRAQAAGSSVLRELHTADS
                     VVNGSAQADVPKELEREESGAAESPALVTPDSEKSAKHGSGAFYSPELLEALTLRFEA
                     PDSRNRWDRPLFTLVGLEEPLPLAGIRSALFENRAPPPHQSTQSQPLASGSFLHQLDQ
                     VTSQVLAGLMEAQKSAVPGDLLTLPGTTEHLRFTRPLTMAELSRLRRQFISYTKMHPN
                     NENLPQLANMFLQYLSQSLH"
     regulatory      1685..1690
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KTI12"
                     /gene_synonym="SBBI81; TOT4"
                     /note="hexamer: AATAAA"
     polyA_site      1708
                     /gene="KTI12"
                     /gene_synonym="SBBI81; TOT4"
                     /note="major polyA site"
ORIGIN      
        1 aacccggaag ttggcgcagc gcggttgcca atggtcgctc cctgagagga tgccgctcgt
       61 ggtgttttgc gggctgccgt acagcggcaa gagccggcgt gctgaagagt tgcgcgtggc
      121 gctggctgcc gagggccgcg cggtgtacgt ggtggacgac gcagctgtcc tgggcgcaga
      181 ggacccagcg gtgtacggcg attctgcccg tgagaaggca ttgcgtggag ctctgcgagc
      241 ctccgtggaa cggcgcctga gtcgccacga cgtggtcatc ctggactcgc ttaactacat
      301 caaaggtttc cgttacgagc tctactgcct ggcacgggcg gcgcgcaccc cgctctgcct
      361 ggtctactgc gtacggcccg gcggcccgat cgcgggacct caggtggcgg gcgcgaacga
      421 gaaccctggc cggaacgtca gtgtgagttg gcggccacgc gctgaggagg acgggagagc
      481 ccaggcggcg ggcagcagcg tcctcaggga actgcatact gcggactctg tagtaaatgg
      541 aagtgcccag gccgacgtac ccaaggaact ggagcgagaa gaatccgggg ctgcggagtc
      601 tccagctctt gtgactccgg attcagagaa atctgcaaag catgggtccg gtgcctttta
      661 ctctcccgaa ctcctggagg ccctaacgct gcgctttgag gctcccgatt ctcggaatcg
      721 ctgggaccgg cctttattca ctttggtggg cctagaggag ccgttgcccc tggcggggat
      781 ccgctctgcc ctgtttgaga accgggcccc accaccccat cagtctacgc agtcccagcc
      841 cctcgcctcc ggcagctttc tgcaccagtt ggaccaggtc acgagtcaag tactggccgg
      901 attgatggaa gcgcagaaga gcgctgtccc cggggacttg ctcacgcttc ctggtaccac
      961 agagcacttg cggtttaccc ggcccttgac catggcagaa ctgagtcgcc ttcgtcgcca
     1021 gtttatttcg tacactaaaa tgcatcccaa caatgagaac ttgccgcaac tggccaacat
     1081 gtttcttcag tatttgagcc agagcctgca ctgaccagag gaggtagggg ggaagccatg
     1141 gcttctgatc tccactccac tttatttctc tgggaaaaat aggctgcagg tctccagagc
     1201 atatcgatgc agtactgtac tagagctgtt gtgactgatt cactcaaact ttcctgcata
     1261 cccctgtgcc aggccttggg tttacagcat aagttcagac taaagagaat ggagaactat
     1321 tgtggtgcaa cctggcaaat ccctcagagg acagagctaa ggtggacagg gattacctag
     1381 attggatcct acttgggcta tcacagagca ttgaccattg gcttccctca tctgaggcgt
     1441 gggagagcag actggataga tgagaattgt tttaaaacaa ttgtgaacag aaactgaaga
     1501 tggtacagtt ctacatctgc acctgccctt ttttcatacc acaaaagtat tttttgagta
     1561 ctgtactgac tttttgctag tttctattct gggaccgagt tcacagataa atccattggt
     1621 ttgtatcctt gagaaacttt gtttttgtgg aagtaagaaa gttatctact agattatttc
     1681 ctctaataaa atcttttaaa atagtcta
//
