LOCUS       XM_047436992            5490 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens kinase suppressor of ras 1 (KSR1),
            transcript variant X13, mRNA.
ACCESSION   XM_047436992
VERSION     XM_047436992.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5490
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..5490
                     /gene="KSR1"
                     /gene_synonym="KSR; RSU2"
                     /note="kinase suppressor of ras 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 23 ESTs, 371 long SRA reads, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 2 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:8844"
                     /db_xref="HGNC:HGNC:6465"
                     /db_xref="MIM:601132"
     CDS             603..2447
                     /gene="KSR1"
                     /gene_synonym="KSR; RSU2"
                     /codon_start=1
                     /product="kinase suppressor of Ras 1 isoform X9"
                     /protein_id="XP_047292948.1"
                     /db_xref="GeneID:8844"
                     /db_xref="HGNC:HGNC:6465"
                     /db_xref="MIM:601132"
                     /translation="MVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKC
                     HNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPA
                     MNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPAAYFIHH
                     RQQFIFPVPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKADVL
                     EAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVYLQEWDIPFEQ
                     VELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVV
                     LFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKG
                     IVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVRE
                     MTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLT
                     SVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGHFWKSADRWRS
                     RYYGKGRYGHPDFKSSCPILEEYINSSKVVPRFERFGLGVLESSNPKM"
ORIGIN      
        1 ctcctgacct caggtgatct tcctgcctca gcctcccaaa gtgctgggat tacaggtgtg
       61 agccactgcg cccagtcatg cccatgtgtt ttggtggtct tggctgctga tgggtggggt
      121 gagccccagg aggaagttgg gacaagtcaa cctcatggca gatgtgccag ggagagctgc
      181 gggtgagata gattgttcct atccccctct ccttgatgtg ggaggactca gtacctccag
      241 cacacccttc tcatggaggt tggttatgtg gtacttggcc tcaagtgaac cagcacttca
      301 tgagtccagc tttgtgctag accagcactt gggattgagg ggggcagtgg ccaccctcgg
      361 gggaccttct gactcagagg acatgagatg gccacactcg agcactgtgt tcctgacctt
      421 tctgggtcac aggtcacctt gatgattgga tgaaagtctt agatcttctt tccagagaaa
      481 agtctacaac attctactga accagtccag agggttcccg gacccccgaa gcccacccat
      541 gggctggctc tgggaggcaa tggcgctgag tatgggggca tctctcgcat ggatccccac
      601 agatggtacg gagggatatc gggctgtcgg tgacgcacag gttctccacc aagtcctggc
      661 tgtcgcaggt ctgccacgtg tgccagaaga gcatgatatt tggagtgaag tgcaagcatt
      721 gcaggttgaa gtgtcacaac aaatgtacca aagaagcccc tgcctgtaga atatccttcc
      781 tgccactaac tcggcttcgg aggacagaat ctgtcccctc ggacatcaac aacccggtgg
      841 acagagcagc cgaaccccat tttggaaccc tccccaaagc actgacaaag aaggagcacc
      901 ctccggccat gaatcacctg gactccagca gcaacccttc ctccaccacc tcctccacac
      961 cctcctcacc ggcgcccttc ccgacatcat ccaacccatc cagcgccacc acgcccccca
     1021 acccctcacc tggccagcgg gacagcaggt tcaacttccc agctgcctac ttcattcatc
     1081 atagacagca gtttatcttt ccagtgccat ctgctggcca ttgctggaaa tgcctcctta
     1141 ttgcagaaag tttaaaggaa aacgctttca acatttcagc ctttgcacac gcagccccgc
     1201 tccctgaagc tgccgacggt acccggctcg atgaccagcc gaaagcagat gtgttggaag
     1261 ctcacgaagc ggaggctgag gagccagagg ctggcaagtc agaggcagaa gacgatgagg
     1321 acgaggtgga cgacttgccg agctctcgcc ggccctggcg gggccccatc tctcgcaagg
     1381 ccagccagac cagcgtgtac ctgcaggagt gggacatccc cttcgagcag gtagagctgg
     1441 gcgagcccat cgggcagggc cgctggggcc gggtgcaccg cggccgctgg catggcgagg
     1501 tggccattcg cctgctggag atggacggcc acaaccagga ccacctgaag ctcttcaaga
     1561 aagaggtgat gaactaccgg cagacgcggc atgagaacgt ggtgctcttc atgggggcct
     1621 gcatgaaccc gccccacctg gccattatca ccagcttctg caaggggcgg acgttgcact
     1681 cgtttgtgag ggaccccaag acgtctctgg acatcaacaa gacgaggcaa atcgctcagg
     1741 agatcatcaa gggcatggga tatcttcatg ccaagggcat cgtacacaaa gatctcaaat
     1801 ctaagaacgt cttctatgac aacggcaagg tggtcatcac agacttcggg ctgtttggga
     1861 tctcaggcgt ggtccgagag ggacggcgtg agaaccagct aaagctgtcc cacgactggc
     1921 tgtgctatct ggcccctgag attgtacgcg agatgacccc cgggaaggac gaggatcagc
     1981 tgccattctc caaagctgct gatgtctatg catttgggac tgtttggtat gagctgcaag
     2041 caagagactg gcccttgaag aaccaggctg cagaggcatc catctggcag attggaagcg
     2101 gggaaggaat gaagcgtgtc ctgacttctg tcagcttggg gaaggaagtc agtgagatcc
     2161 tgtcggcctg ctgggctttc gacctgcagg agagacccag cttcagcctg ctgatggaca
     2221 tgctggagaa acttcccaag ctgaaccggc ggctctccca ccctggacac ttctggaagt
     2281 cagctgatcg ctggaggagc cgctactatg gaaaaggacg ctacggccac cctgacttta
     2341 agagctcctg tccgattctg gaggaataca ttaacagcag caaagttgta ccccggtttg
     2401 aaaggtttgg cttgggcgtc ctggagtcca gtaatccaaa gatgtagcca gccatatggt
     2461 ttttcgctgc tgatctcttt ctttttaaaa tgtgtttctg aaacatccca acaaccacca
     2521 cgacaaaaaa acactgcctg cccagcgctg caaaccagga gcacacgtcc tagattcaga
     2581 ctgttggcca taaaccccac tcgggagatg gagctgcacc tgctatttct taaaatgaca
     2641 ccaccaacaa ccaaacctgt catgacagac agcaaatgtt tacacgtata tttctcctga
     2701 gtgaacctga tgttttacaa taggtaataa taaaaacagt ctgtgcagat gcactggcac
     2761 tgacggccag gatggcggaa atggccatcc cctctgagga ccttgtaggc ggtgagggac
     2821 ccatgctggg ccagaaggaa gacaaacatg gtaattgcag ctgttcttgg ggtagggcgg
     2881 ggagcccaga aggtctgatc tggcctctgc tttttggccc aagactccat cagggaaatc
     2941 tatctagggc tctccccttg tcctttcaaa gggatactgc cccttcctcg tcttgcagag
     3001 gaaaccctgg ctaggaactg agctagttta tggagtctgg aattcctgga gagcttgggt
     3061 tcaccttctc acccctgtaa tccaggctgc tcctgctgga aaagtagaaa cagaatccaa
     3121 aaaaggtctg gactcacccg gtggttccca gccagggttt ctgctgcaag gtgaggaaac
     3181 atccatggct tgtacagatg tgagtctttg atgaagcccc caggcaggca ccaaggtgat
     3241 gggactcagg gccttggctt ttagatacat cccagtccct gactgacatc tgaccatgag
     3301 ggctggatgg gtgggaacaa ggaggagtag atggcaaaag tacctgagcc cacttcccag
     3361 ccacagggtg accctggcac tgtaaaaacc ctttgtcagt catgccagaa ggttctagaa
     3421 ctgcccacct cttccatttc agtcctgctg aaacccctta gcctatttcc gactcctctg
     3481 tccatgctct gagttcagct gggcagtgtg tgggctatca cccctttcat ttagacctac
     3541 ctagctggcc cccatctgca gagccttcct tagcaccatt aggccttcta cttgtgtcca
     3601 tttgaagcag gaggggctgg atttggaaaa gtctttgaag tgagagcacc acgcttgtct
     3661 tcgttagaaa ctcttaactg cagaaaaaag ttccagatgg caagggagcc cttaagtgga
     3721 gattaggttg cattagactc caaaaccaga aaggaaaaag ggtgatggga gtggagacgt
     3781 gattggattc aggcccagaa cctgtgacca tgctctgagc tcagacttgg ggagggaggg
     3841 gtgtggctcc caccccttcc agttaagacc tgcctagcag agccccagtc tccagcccct
     3901 tccctagcac cagagtctgg tcaaaatgcc acagaaaatg agctgctctg ccagcaagct
     3961 gtggagctgc ctcctctcca ggcctggcat cccttggtca gcccctcctg ggagggcaca
     4021 gccgtattac agtgccagtg tgcctggcca tcagcatctt cacccttccc agtctgtgtg
     4081 gggaggctgt aaaccccgtg gattcagctc cgtgtggagt ttctgtgcta tggtgggact
     4141 gctcattttg ccccatcatc cctttggcct cccacacacc tgccccttcc cagggatcac
     4201 gtgtgtctcc agcctttcac ctttctattg caatggtggc ctttgtccag gcaagagcag
     4261 gcctgatgga tgtactggtg agccccacag ttggatgtca gctcagccgt ccaactggga
     4321 ggaacagtag gctcagttcc tccctgaccc ctgacaccag gccgcagtgg gcatgcacag
     4381 gcccacagaa agtcagtctg ggttttgctt ttctcgtgag catcacagtt aaagaagcgc
     4441 tcattgagca actacagtgc acttggtctt ctgcaagtgc tgggcaccta gagataggaa
     4501 cagtcatggt ccctgctctt aaggaactga tgacctggtg gggccctgtt gtcttcaagg
     4561 aacccagaag ccactgggcc ccaaaggtgg aactgaagga ctgggggcag ctggctctca
     4621 gcctgccacc tctgcactgc ctgcctttaa agaaccccac cccaccccat gatggccccc
     4681 tctgttcccc ttgtatttca gtgactgtga attgaggtta ggaaggcaca cctgcccttc
     4741 tgtgtgctct ctccacacga aggatgacag atactgtgaa ttcagccctc acggccaact
     4801 gtgaagggga tggagaaggc tgggagggct cggggagagc tcttaggggc tgcggaagtc
     4861 cccacggggg tctgagagtg gagcccaagc tttggccctc caggcatccc cagtttccag
     4921 cctcacctct gaagccctgc tgcctttaac caccagagcc gcagccccct gggtttctgt
     4981 ctaactcgaa gtcttgaatc ctagctagtt tggggttgtg agcagtgtgt agcaaagttg
     5041 atctctccat gtcaccaaat caaaacaccc tctgtcatcc tacggcattt cctcttgagg
     5101 tcacagagag gaatggcaag ccctggaaac ctgtgttatt ctgtgttgat ttggtgtggg
     5161 gggagggtgg agacgtaaat gtgaagccag ttggagtttg tgctatgcag cagtgttagc
     5221 caggatctca tcagcgtgca aacctagcat cttctgtggc cacaagccac acacttgctt
     5281 tttttgaatg tgatgtaaaa tttgtacagt aaagttttta tattttctat caactacatt
     5341 tgtcttccag acatgctatt aatttaaatt aaaatggtta gtattaacaa acatgctgta
     5401 tcgggttttt ttgccactgg caagaacatg ccctctgtgc taagccaggc ctgggtgtct
     5461 ggagtttgtg aataaagtta taccaaggtg
//
