LOCUS       XM_047436989            6286 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens kinase suppressor of ras 1 (KSR1),
            transcript variant X10, mRNA.
ACCESSION   XM_047436989
VERSION     XM_047436989.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 14% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..6286
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..6286
                     /gene="KSR1"
                     /gene_synonym="KSR; RSU2"
                     /note="kinase suppressor of ras 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 28 ESTs, 372 long SRA reads, 1 Protein, and 94%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 1 sample with support for all
                     annotated introns"
                     /db_xref="GeneID:8844"
                     /db_xref="HGNC:HGNC:6465"
                     /db_xref="MIM:601132"
     CDS             802..3243
                     /gene="KSR1"
                     /gene_synonym="KSR; RSU2"
                     /codon_start=1
                     /product="kinase suppressor of Ras 1 isoform X8"
                     /protein_id="XP_047292945.1"
                     /db_xref="GeneID:8844"
                     /db_xref="HGNC:HGNC:6465"
                     /db_xref="MIM:601132"
                     /translation="MNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDS
                     SWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSP
                     TPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVF
                     QLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSW
                     LSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLPLTRLRRTESVPSDINN
                     PVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSA
                     TTPPNPSPGQRDSRFNFPAAYFIHHRQQFIFPVPSAGHCWKCLLIAESLKENAFNISA
                     FAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRP
                     WRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDG
                     HNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKT
                     SLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVR
                     EGRRENQLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDW
                     PLKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDML
                     EKLPKLNRRLSHPGHFWKSADRWRSRYYGKGRYGHPDFKSSCPILEEYINSSKVVPRF
                     ERFGLGVLESSNPKM"
ORIGIN      
        1 gtcgccgcgg ctttcgcttt gctgccgcgg ctgggagggt ggaagcggca gactcagcgg
       61 ccggctctac cggcgtcccg gctcgggcag cgccgagggg cgctcctggt ccagctctcc
      121 tggctcgggg gttccttgcc gaggcgcccg cgccccgggc tcccagcctc ggccgccgcg
      181 gccccgatgc cgaggcatgg atagagcagc gctgcgcgcg gcggcgatgg gagagaagaa
      241 ggagggcggt ggcggggggg atgcggcggc cgcggaggga ggcgcagggg ccgcggccag
      301 ccgggcgctg cagcagtgcg ggcagctcca gaagctcatc gacatctcca tcggcagcct
      361 gcgcgggctg cgcaccaagt gcgctgtgtc caacgacctc acccagcagg agatacggac
      421 cctggaggtg actggactga tgttctgttc tagatgaaac tccttgaggg gaccatttga
      481 aaaggcttga tgtgctgccc aaagccccct tcagagctga cttctccacc cccagctgcc
      541 gtgagccttg gctgctgaca gctcatagct gagtccctcc cgtgaagtca ccttctgctg
      601 aagggtacat cctctcccaa ggcgaagctg gtccgttaca tttgtaagca gaggcagtgc
      661 aagctgagcg tggctcccgg tgagaggacc ccagagctca acagctaccc ccgcttcagc
      721 gactggctgt acactttcaa cgtgaggccg gaggtggtgc aggagatccc ccgagacctc
      781 acgctggatg ccctgctgga gatgaatgag gccaaggtga aggagacgct gcggcgctgt
      841 ggggccagcg gggatgagtg tggccgtctg cagtatgccc tcacctgcct gcggaaggtg
      901 acaggcctgg gaggggagca caaggaggac tccagttgga gttcattgga tgcgcggcgg
      961 gaaagtggct cagggccttc cacggacacc ctctcagcag ccagcctgcc ctggccccca
     1021 gggagctccc agctgggcag agcaggcaac agcgcccagg gcccacgctc catctccgtg
     1081 tcagctctgc ccgcctcaga ctcccccacc cccagcttca gtgagggcct ctcagacacc
     1141 tgtattcccc tgcacgccag cggccggctg accccccgtg ccctgcacag cttcatcacc
     1201 ccgcccacca caccccagct gcgacggcac accaagctga agccaccacg gacgcccccc
     1261 ccacccagcc gcaaggtctt ccagctgctg cccagcttcc ccacactcac ccggagcaag
     1321 tcccatgagt ctcagctggg gaaccgcatt gatgacgtct cctcgatgag gtttgatctc
     1381 tcgcatggat ccccacagat ggtacggagg gatatcgggc tgtcggtgac gcacaggttc
     1441 tccaccaagt cctggctgtc gcaggtctgc cacgtgtgcc agaagagcat gatatttgga
     1501 gtgaagtgca agcattgcag gttgaagtgt cacaacaaat gtaccaaaga agcccctgcc
     1561 tgtagaatat ccttcctgcc actaactcgg cttcggagga cagaatctgt cccctcggac
     1621 atcaacaacc cggtggacag agcagccgaa ccccattttg gaaccctccc caaagcactg
     1681 acaaagaagg agcaccctcc ggccatgaat cacctggact ccagcagcaa cccttcctcc
     1741 accacctcct ccacaccctc ctcaccggcg cccttcccga catcatccaa cccatccagc
     1801 gccaccacgc cccccaaccc ctcacctggc cagcgggaca gcaggttcaa cttcccagct
     1861 gcctacttca ttcatcatag acagcagttt atctttccag tgccatctgc tggccattgc
     1921 tggaaatgcc tccttattgc agaaagttta aaggaaaacg ctttcaacat ttcagccttt
     1981 gcacacgcag ccccgctccc tgaagctgcc gacggtaccc ggctcgatga ccagccgaaa
     2041 gcagatgtgt tggaagctca cgaagcggag gctgaggagc cagaggctgg caagtcagag
     2101 gcagaagacg atgaggacga ggtggacgac ttgccgagct ctcgccggcc ctggcggggc
     2161 cccatctctc gcaaggccag ccagaccagc gtgtacctgc aggagtggga catccccttc
     2221 gagcaggtag agctgggcga gcccatcggg cagggccgct ggggccgggt gcaccgcggc
     2281 cgctggcatg gcgaggtggc cattcgcctg ctggagatgg acggccacaa ccaggaccac
     2341 ctgaagctct tcaagaaaga ggtgatgaac taccggcaga cgcggcatga gaacgtggtg
     2401 ctcttcatgg gggcctgcat gaacccgccc cacctggcca ttatcaccag cttctgcaag
     2461 gggcggacgt tgcactcgtt tgtgagggac cccaagacgt ctctggacat caacaagacg
     2521 aggcaaatcg ctcaggagat catcaagggc atgggatatc ttcatgccaa gggcatcgta
     2581 cacaaagatc tcaaatctaa gaacgtcttc tatgacaacg gcaaggtggt catcacagac
     2641 ttcgggctgt ttgggatctc aggcgtggtc cgagagggac ggcgtgagaa ccagctaaag
     2701 ctgtcccacg actggctgtg ctatctggcc cctgagattg tacgcgagat gacccccggg
     2761 aaggacgagg atcagctgcc attctccaaa gctgctgatg tctatgcatt tgggactgtt
     2821 tggtatgagc tgcaagcaag agactggccc ttgaagaacc aggctgcaga ggcatccatc
     2881 tggcagattg gaagcgggga aggaatgaag cgtgtcctga cttctgtcag cttggggaag
     2941 gaagtcagtg agatcctgtc ggcctgctgg gctttcgacc tgcaggagag acccagcttc
     3001 agcctgctga tggacatgct ggagaaactt cccaagctga accggcggct ctcccaccct
     3061 ggacacttct ggaagtcagc tgatcgctgg aggagccgct actatggaaa aggacgctac
     3121 ggccaccctg actttaagag ctcctgtccg attctggagg aatacattaa cagcagcaaa
     3181 gttgtacccc ggtttgaaag gtttggcttg ggcgtcctgg agtccagtaa tccaaagatg
     3241 tagccagcca tatggttttt cgctgctgat ctctttcttt ttaaaatgtg tttctgaaac
     3301 atcccaacaa ccaccacgac aaaaaaacac tgcctgccca gcgctgcaaa ccaggagcac
     3361 acgtcctaga ttcagactgt tggccataaa ccccactcgg gagatggagc tgcacctgct
     3421 atttcttaaa atgacaccac caacaaccaa acctgtcatg acagacagca aatgtttaca
     3481 cgtatatttc tcctgagtga acctgatgtt ttacaatagg taataataaa aacagtctgt
     3541 gcagatgcac tggcactgac ggccaggatg gcggaaatgg ccatcccctc tgaggacctt
     3601 gtaggcggtg agggacccat gctgggccag aaggaagaca aacatggtaa ttgcagctgt
     3661 tcttggggta gggcggggag cccagaaggt ctgatctggc ctctgctttt tggcccaaga
     3721 ctccatcagg gaaatctatc tagggctctc cccttgtcct ttcaaaggga tactgcccct
     3781 tcctcgtctt gcagaggaaa ccctggctag gaactgagct agtttatgga gtctggaatt
     3841 cctggagagc ttgggttcac cttctcaccc ctgtaatcca ggctgctcct gctggaaaag
     3901 tagaaacaga atccaaaaaa ggtctggact cacccggtgg ttcccagcca gggtttctgc
     3961 tgcaaggtga ggaaacatcc atggcttgta cagatgtgag tctttgatga agcccccagg
     4021 caggcaccaa ggtgatggga ctcagggcct tggcttttag atacatccca gtccctgact
     4081 gacatctgac catgagggct ggatgggtgg gaacaaggag gagtagatgg caaaagtacc
     4141 tgagcccact tcccagccac agggtgaccc tggcactgta aaaacccttt gtcagtcatg
     4201 ccagaaggtt ctagaactgc ccacctcttc catttcagtc ctgctgaaac cccttagcct
     4261 atttccgact cctctgtcca tgctctgagt tcagctgggc agtgtgtggg ctatcacccc
     4321 tttcatttag acctacctag ctggccccca tctgcagagc cttccttagc accattaggc
     4381 cttctacttg tgtccatttg aagcaggagg ggctggattt ggaaaagtct ttgaagtgag
     4441 agcaccacgc ttgtcttcgt tagaaactct taactgcaga aaaaagttcc agatggcaag
     4501 ggagccctta agtggagatt aggttgcatt agactccaaa accagaaagg aaaaagggtg
     4561 atgggagtgg agacgtgatt ggattcaggc ccagaacctg tgaccatgct ctgagctcag
     4621 acttggggag ggaggggtgt ggctcccacc ccttccagtt aagacctgcc tagcagagcc
     4681 ccagtctcca gccccttccc tagcaccaga gtctggtcaa aatgccacag aaaatgagct
     4741 gctctgccag caagctgtgg agctgcctcc tctccaggcc tggcatccct tggtcagccc
     4801 ctcctgggag ggcacagccg tattacagtg ccagtgtgcc tggccatcag catcttcacc
     4861 cttcccagtc tgtgtgggga ggctgtaaac cccgtggatt cagctccgtg tggagtttct
     4921 gtgctatggt gggactgctc attttgcccc atcatccctt tggcctccca cacacctgcc
     4981 ccttcccagg gatcacgtgt gtctccagcc tttcaccttt ctattgcaat ggtggccttt
     5041 gtccaggcaa gagcaggcct gatggatgta ctggtgagcc ccacagttgg atgtcagctc
     5101 agccgtccaa ctgggaggaa cagtaggctc agttcctccc tgacccctga caccaggccg
     5161 cagtgggcat gcacaggccc acagaaagtc agtctgggtt ttgcttttct cgtgagcatc
     5221 acagttaaag aagcgctcat tgagcaacta cagtgcactt ggtcttctgc aagtgctggg
     5281 cacctagaga taggaacagt catggtccct gctcttaagg aactgatgac ctggtggggc
     5341 cctgttgtct tcaaggaacc cagaagccac tgggccccaa aggtggaact gaaggactgg
     5401 gggcagctgg ctctcagcct gccacctctg cactgcctgc ctttaaagaa ccccacccca
     5461 ccccatgatg gccccctctg ttccccttgt atttcagtga ctgtgaattg aggttaggaa
     5521 ggcacacctg cccttctgtg tgctctctcc acacgaagga tgacagatac tgtgaattca
     5581 gccctcacgg ccaactgtga aggggatgga gaaggctggg agggctcggg gagagctctt
     5641 aggggctgcg gaagtcccca cgggggtctg agagtggagc ccaagctttg gccctccagg
     5701 catccccagt ttccagcctc acctctgaag ccctgctgcc tttaaccacc agagccgcag
     5761 ccccctgggt ttctgtctaa ctcgaagtct tgaatcctag ctagtttggg gttgtgagca
     5821 gtgtgtagca aagttgatct ctccatgtca ccaaatcaaa acaccctctg tcatcctacg
     5881 gcatttcctc ttgaggtcac agagaggaat ggcaagccct ggaaacctgt gttattctgt
     5941 gttgatttgg tgtgggggga gggtggagac gtaaatgtga agccagttgg agtttgtgct
     6001 atgcagcagt gttagccagg atctcatcag cgtgcaaacc tagcatcttc tgtggccaca
     6061 agccacacac ttgctttttt tgaatgtgat gtaaaatttg tacagtaaag tttttatatt
     6121 ttctatcaac tacatttgtc ttccagacat gctattaatt taaattaaaa tggttagtat
     6181 taacaaacat gctgtatcgg gtttttttgc cactggcaag aacatgccct ctgtgctaag
     6241 ccaggcctgg gtgtctggag tttgtgaata aagttatacc aaggtg
//
