LOCUS       XM_047436986            5984 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens kinase suppressor of ras 1 (KSR1),
            transcript variant X3, mRNA.
ACCESSION   XM_047436986
VERSION     XM_047436986.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5984
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..5984
                     /gene="KSR1"
                     /gene_synonym="KSR; RSU2"
                     /note="kinase suppressor of ras 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 29 ESTs, 376 long SRA reads, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 5 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:8844"
                     /db_xref="HGNC:HGNC:6465"
                     /db_xref="MIM:601132"
     CDS             197..2941
                     /gene="KSR1"
                     /gene_synonym="KSR; RSU2"
                     /codon_start=1
                     /product="kinase suppressor of Ras 1 isoform X3"
                     /protein_id="XP_047292942.1"
                     /db_xref="GeneID:8844"
                     /db_xref="HGNC:HGNC:6465"
                     /db_xref="MIM:601132"
                     /translation="MDRAALRAAAMGEKKEGGGGGDAAAAEGGAGAAASRALQQCGQL
                     QKLIDISIGSLRGLRTKCAVSNDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPE
                     LNSYPRFSDWLYTFNVRPEVVQEIPRDLTLDALLEMNEAKVKETLRRCGASGDECGRL
                     QYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRA
                     GNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQ
                     LRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGS
                     PQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACR
                     ISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSS
                     TTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPDISAFAHAAPLPEAADGTR
                     LDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVY
                     LQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMN
                     YRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEII
                     KGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWL
                     CYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIG
                     SGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGH
                     FWKSADRWRSRYYGKGRYGHPDFKSSCPILEEYINSSKVVPRFERFGLGVLESSNPKM
                     "
ORIGIN      
        1 gtcgccgcgg ctttcgcttt gctgccgcgg ctgggagggt ggaagcggca gactcagcgg
       61 ccggctctac cggcgtcccg gctcgggcag cgccgagggg cgctcctggt ccagctctcc
      121 tggctcgggg gttccttgcc gaggcgcccg cgccccgggc tcccagcctc ggccgccgcg
      181 gccccgatgc cgaggcatgg atagagcagc gctgcgcgcg gcggcgatgg gagagaagaa
      241 ggagggcggt ggcggggggg atgcggcggc cgcggaggga ggcgcagggg ccgcggccag
      301 ccgggcgctg cagcagtgcg ggcagctcca gaagctcatc gacatctcca tcggcagcct
      361 gcgcgggctg cgcaccaagt gcgctgtgtc caacgacctc acccagcagg agatacggac
      421 cctggaggcg aagctggtcc gttacatttg taagcagagg cagtgcaagc tgagcgtggc
      481 tcccggtgag aggaccccag agctcaacag ctacccccgc ttcagcgact ggctgtacac
      541 tttcaacgtg aggccggagg tggtgcagga gatcccccga gacctcacgc tggatgccct
      601 gctggagatg aatgaggcca aggtgaagga gacgctgcgg cgctgtgggg ccagcgggga
      661 tgagtgtggc cgtctgcagt atgccctcac ctgcctgcgg aaggtgacag gcctgggagg
      721 ggagcacaag gaggactcca gttggagttc attggatgcg cggcgggaaa gtggctcagg
      781 gccttccacg gacaccctct cagcagccag cctgccctgg cccccaggga gctcccagct
      841 gggcagagca ggcaacagcg cccagggccc acgctccatc tccgtgtcag ctctgcccgc
      901 ctcagactcc cccaccccca gcttcagtga gggcctctca gacacctgta ttcccctgca
      961 cgccagcggc cggctgaccc cccgtgccct gcacagcttc atcaccccgc ccaccacacc
     1021 ccagctgcga cggcacacca agctgaagcc accacggacg ccccccccac ccagccgcaa
     1081 ggtcttccag ctgctgccca gcttccccac actcacccgg agcaagtccc atgagtctca
     1141 gctggggaac cgcattgatg acgtctcctc gatgaggttt gatctctcgc atggatcccc
     1201 acagatggta cggagggata tcgggctgtc ggtgacgcac aggttctcca ccaagtcctg
     1261 gctgtcgcag gtctgccacg tgtgccagaa gagcatgata tttggagtga agtgcaagca
     1321 ttgcaggttg aagtgtcaca acaaatgtac caaagaagcc cctgcctgta gaatatcctt
     1381 cctgccacta actcggcttc ggaggacaga atctgtcccc tcggacatca acaacccggt
     1441 ggacagagca gccgaacccc attttggaac cctccccaaa gcactgacaa agaaggagca
     1501 ccctccggcc atgaatcacc tggactccag cagcaaccct tcctccacca cctcctccac
     1561 accctcctca ccggcgccct tcccgacatc atccaaccca tccagcgcca ccacgccccc
     1621 caacccctca cctggccagc gggacagcag gttcaacttc ccagacattt cagcctttgc
     1681 acacgcagcc ccgctccctg aagctgccga cggtacccgg ctcgatgacc agccgaaagc
     1741 agatgtgttg gaagctcacg aagcggaggc tgaggagcca gaggctggca agtcagaggc
     1801 agaagacgat gaggacgagg tggacgactt gccgagctct cgccggccct ggcggggccc
     1861 catctctcgc aaggccagcc agaccagcgt gtacctgcag gagtgggaca tccccttcga
     1921 gcaggtagag ctgggcgagc ccatcgggca gggccgctgg ggccgggtgc accgcggccg
     1981 ctggcatggc gaggtggcca ttcgcctgct ggagatggac ggccacaacc aggaccacct
     2041 gaagctcttc aagaaagagg tgatgaacta ccggcagacg cggcatgaga acgtggtgct
     2101 cttcatgggg gcctgcatga acccgcccca cctggccatt atcaccagct tctgcaaggg
     2161 gcggacgttg cactcgtttg tgagggaccc caagacgtct ctggacatca acaagacgag
     2221 gcaaatcgct caggagatca tcaagggcat gggatatctt catgccaagg gcatcgtaca
     2281 caaagatctc aaatctaaga acgtcttcta tgacaacggc aaggtggtca tcacagactt
     2341 cgggctgttt gggatctcag gcgtggtccg agagggacgg cgtgagaacc agctaaagct
     2401 gtcccacgac tggctgtgct atctggcccc tgagattgta cgcgagatga cccccgggaa
     2461 ggacgaggat cagctgccat tctccaaagc tgctgatgtc tatgcatttg ggactgtttg
     2521 gtatgagctg caagcaagag actggccctt gaagaaccag gctgcagagg catccatctg
     2581 gcagattgga agcggggaag gaatgaagcg tgtcctgact tctgtcagct tggggaagga
     2641 agtcagtgag atcctgtcgg cctgctgggc tttcgacctg caggagagac ccagcttcag
     2701 cctgctgatg gacatgctgg agaaacttcc caagctgaac cggcggctct cccaccctgg
     2761 acacttctgg aagtcagctg atcgctggag gagccgctac tatggaaaag gacgctacgg
     2821 ccaccctgac tttaagagct cctgtccgat tctggaggaa tacattaaca gcagcaaagt
     2881 tgtaccccgg tttgaaaggt ttggcttggg cgtcctggag tccagtaatc caaagatgta
     2941 gccagccata tggtttttcg ctgctgatct ctttcttttt aaaatgtgtt tctgaaacat
     3001 cccaacaacc accacgacaa aaaaacactg cctgcccagc gctgcaaacc aggagcacac
     3061 gtcctagatt cagactgttg gccataaacc ccactcggga gatggagctg cacctgctat
     3121 ttcttaaaat gacaccacca acaaccaaac ctgtcatgac agacagcaaa tgtttacacg
     3181 tatatttctc ctgagtgaac ctgatgtttt acaataggta ataataaaaa cagtctgtgc
     3241 agatgcactg gcactgacgg ccaggatggc ggaaatggcc atcccctctg aggaccttgt
     3301 aggcggtgag ggacccatgc tgggccagaa ggaagacaaa catggtaatt gcagctgttc
     3361 ttggggtagg gcggggagcc cagaaggtct gatctggcct ctgctttttg gcccaagact
     3421 ccatcaggga aatctatcta gggctctccc cttgtccttt caaagggata ctgccccttc
     3481 ctcgtcttgc agaggaaacc ctggctagga actgagctag tttatggagt ctggaattcc
     3541 tggagagctt gggttcacct tctcacccct gtaatccagg ctgctcctgc tggaaaagta
     3601 gaaacagaat ccaaaaaagg tctggactca cccggtggtt cccagccagg gtttctgctg
     3661 caaggtgagg aaacatccat ggcttgtaca gatgtgagtc tttgatgaag cccccaggca
     3721 ggcaccaagg tgatgggact cagggccttg gcttttagat acatcccagt ccctgactga
     3781 catctgacca tgagggctgg atgggtggga acaaggagga gtagatggca aaagtacctg
     3841 agcccacttc ccagccacag ggtgaccctg gcactgtaaa aaccctttgt cagtcatgcc
     3901 agaaggttct agaactgccc acctcttcca tttcagtcct gctgaaaccc cttagcctat
     3961 ttccgactcc tctgtccatg ctctgagttc agctgggcag tgtgtgggct atcacccctt
     4021 tcatttagac ctacctagct ggcccccatc tgcagagcct tccttagcac cattaggcct
     4081 tctacttgtg tccatttgaa gcaggagggg ctggatttgg aaaagtcttt gaagtgagag
     4141 caccacgctt gtcttcgtta gaaactctta actgcagaaa aaagttccag atggcaaggg
     4201 agcccttaag tggagattag gttgcattag actccaaaac cagaaaggaa aaagggtgat
     4261 gggagtggag acgtgattgg attcaggccc agaacctgtg accatgctct gagctcagac
     4321 ttggggaggg aggggtgtgg ctcccacccc ttccagttaa gacctgccta gcagagcccc
     4381 agtctccagc cccttcccta gcaccagagt ctggtcaaaa tgccacagaa aatgagctgc
     4441 tctgccagca agctgtggag ctgcctcctc tccaggcctg gcatcccttg gtcagcccct
     4501 cctgggaggg cacagccgta ttacagtgcc agtgtgcctg gccatcagca tcttcaccct
     4561 tcccagtctg tgtggggagg ctgtaaaccc cgtggattca gctccgtgtg gagtttctgt
     4621 gctatggtgg gactgctcat tttgccccat catccctttg gcctcccaca cacctgcccc
     4681 ttcccaggga tcacgtgtgt ctccagcctt tcacctttct attgcaatgg tggcctttgt
     4741 ccaggcaaga gcaggcctga tggatgtact ggtgagcccc acagttggat gtcagctcag
     4801 ccgtccaact gggaggaaca gtaggctcag ttcctccctg acccctgaca ccaggccgca
     4861 gtgggcatgc acaggcccac agaaagtcag tctgggtttt gcttttctcg tgagcatcac
     4921 agttaaagaa gcgctcattg agcaactaca gtgcacttgg tcttctgcaa gtgctgggca
     4981 cctagagata ggaacagtca tggtccctgc tcttaaggaa ctgatgacct ggtggggccc
     5041 tgttgtcttc aaggaaccca gaagccactg ggccccaaag gtggaactga aggactgggg
     5101 gcagctggct ctcagcctgc cacctctgca ctgcctgcct ttaaagaacc ccaccccacc
     5161 ccatgatggc cccctctgtt ccccttgtat ttcagtgact gtgaattgag gttaggaagg
     5221 cacacctgcc cttctgtgtg ctctctccac acgaaggatg acagatactg tgaattcagc
     5281 cctcacggcc aactgtgaag gggatggaga aggctgggag ggctcgggga gagctcttag
     5341 gggctgcgga agtccccacg ggggtctgag agtggagccc aagctttggc cctccaggca
     5401 tccccagttt ccagcctcac ctctgaagcc ctgctgcctt taaccaccag agccgcagcc
     5461 ccctgggttt ctgtctaact cgaagtcttg aatcctagct agtttggggt tgtgagcagt
     5521 gtgtagcaaa gttgatctct ccatgtcacc aaatcaaaac accctctgtc atcctacggc
     5581 atttcctctt gaggtcacag agaggaatgg caagccctgg aaacctgtgt tattctgtgt
     5641 tgatttggtg tggggggagg gtggagacgt aaatgtgaag ccagttggag tttgtgctat
     5701 gcagcagtgt tagccaggat ctcatcagcg tgcaaaccta gcatcttctg tggccacaag
     5761 ccacacactt gctttttttg aatgtgatgt aaaatttgta cagtaaagtt tttatatttt
     5821 ctatcaacta catttgtctt ccagacatgc tattaattta aattaaaatg gttagtatta
     5881 acaaacatgc tgtatcgggt ttttttgcca ctggcaagaa catgccctct gtgctaagcc
     5941 aggcctgggt gtctggagtt tgtgaataaa gttataccaa ggtg
//
