LOCUS       XM_006722154            5903 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens kinase suppressor of ras 1 (KSR1),
            transcript variant X6, mRNA.
ACCESSION   XM_006722154
VERSION     XM_006722154.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006722154.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..5903
                     /gene="KSR1"
                     /gene_synonym="KSR; RSU2"
                     /note="kinase suppressor of ras 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 26 ESTs, 478 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 93 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:8844"
                     /db_xref="HGNC:HGNC:6465"
                     /db_xref="MIM:601132"
     CDS             197..2860
                     /gene="KSR1"
                     /gene_synonym="KSR; RSU2"
                     /codon_start=1
                     /product="kinase suppressor of Ras 1 isoform X5"
                     /protein_id="XP_006722217.1"
                     /db_xref="GeneID:8844"
                     /db_xref="HGNC:HGNC:6465"
                     /db_xref="MIM:601132"
                     /translation="MDRAALRAAAMGEKKEGGGGGDAAAAEGGAGAAASRALQQCGQL
                     QKLIDISIGSLRGLRTKCAVSNDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPE
                     LNSYPRFSDWLYTFNVRPEVVQEIPRDLTLDALLEMNEAKVKETLRRCGASGDECGRL
                     QYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRA
                     GNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQ
                     LRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGS
                     PQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACR
                     ISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSS
                     TTSSTPSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPDISAFAHAAPLPEAADGTR
                     LDDQPKADVLEAHEAEAEEPEAGKSEAEDDEDEVDDLPSSRRPWRGPISRKASQTSVY
                     LQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMN
                     YRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEII
                     KGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWL
                     CYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIG
                     SGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGH
                     FWKSADINSSKVVPRFERFGLGVLESSNPKM"
ORIGIN      
        1 gtcgccgcgg ctttcgcttt gctgccgcgg ctgggagggt ggaagcggca gactcagcgg
       61 ccggctctac cggcgtcccg gctcgggcag cgccgagggg cgctcctggt ccagctctcc
      121 tggctcgggg gttccttgcc gaggcgcccg cgccccgggc tcccagcctc ggccgccgcg
      181 gccccgatgc cgaggcatgg atagagcagc gctgcgcgcg gcggcgatgg gagagaagaa
      241 ggagggcggt ggcggggggg atgcggcggc cgcggaggga ggcgcagggg ccgcggccag
      301 ccgggcgctg cagcagtgcg ggcagctcca gaagctcatc gacatctcca tcggcagcct
      361 gcgcgggctg cgcaccaagt gcgctgtgtc caacgacctc acccagcagg agatacggac
      421 cctggaggcg aagctggtcc gttacatttg taagcagagg cagtgcaagc tgagcgtggc
      481 tcccggtgag aggaccccag agctcaacag ctacccccgc ttcagcgact ggctgtacac
      541 tttcaacgtg aggccggagg tggtgcagga gatcccccga gacctcacgc tggatgccct
      601 gctggagatg aatgaggcca aggtgaagga gacgctgcgg cgctgtgggg ccagcgggga
      661 tgagtgtggc cgtctgcagt atgccctcac ctgcctgcgg aaggtgacag gcctgggagg
      721 ggagcacaag gaggactcca gttggagttc attggatgcg cggcgggaaa gtggctcagg
      781 gccttccacg gacaccctct cagcagccag cctgccctgg cccccaggga gctcccagct
      841 gggcagagca ggcaacagcg cccagggccc acgctccatc tccgtgtcag ctctgcccgc
      901 ctcagactcc cccaccccca gcttcagtga gggcctctca gacacctgta ttcccctgca
      961 cgccagcggc cggctgaccc cccgtgccct gcacagcttc atcaccccgc ccaccacacc
     1021 ccagctgcga cggcacacca agctgaagcc accacggacg ccccccccac ccagccgcaa
     1081 ggtcttccag ctgctgccca gcttccccac actcacccgg agcaagtccc atgagtctca
     1141 gctggggaac cgcattgatg acgtctcctc gatgaggttt gatctctcgc atggatcccc
     1201 acagatggta cggagggata tcgggctgtc ggtgacgcac aggttctcca ccaagtcctg
     1261 gctgtcgcag gtctgccacg tgtgccagaa gagcatgata tttggagtga agtgcaagca
     1321 ttgcaggttg aagtgtcaca acaaatgtac caaagaagcc cctgcctgta gaatatcctt
     1381 cctgccacta actcggcttc ggaggacaga atctgtcccc tcggacatca acaacccggt
     1441 ggacagagca gccgaacccc attttggaac cctccccaaa gcactgacaa agaaggagca
     1501 ccctccggcc atgaatcacc tggactccag cagcaaccct tcctccacca cctcctccac
     1561 accctcctca ccggcgccct tcccgacatc atccaaccca tccagcgcca ccacgccccc
     1621 caacccctca cctggccagc gggacagcag gttcaacttc ccagacattt cagcctttgc
     1681 acacgcagcc ccgctccctg aagctgccga cggtacccgg ctcgatgacc agccgaaagc
     1741 agatgtgttg gaagctcacg aagcggaggc tgaggagcca gaggctggca agtcagaggc
     1801 agaagacgat gaggacgagg tggacgactt gccgagctct cgccggccct ggcggggccc
     1861 catctctcgc aaggccagcc agaccagcgt gtacctgcag gagtgggaca tccccttcga
     1921 gcaggtagag ctgggcgagc ccatcgggca gggccgctgg ggccgggtgc accgcggccg
     1981 ctggcatggc gaggtggcca ttcgcctgct ggagatggac ggccacaacc aggaccacct
     2041 gaagctcttc aagaaagagg tgatgaacta ccggcagacg cggcatgaga acgtggtgct
     2101 cttcatgggg gcctgcatga acccgcccca cctggccatt atcaccagct tctgcaaggg
     2161 gcggacgttg cactcgtttg tgagggaccc caagacgtct ctggacatca acaagacgag
     2221 gcaaatcgct caggagatca tcaagggcat gggatatctt catgccaagg gcatcgtaca
     2281 caaagatctc aaatctaaga acgtcttcta tgacaacggc aaggtggtca tcacagactt
     2341 cgggctgttt gggatctcag gcgtggtccg agagggacgg cgtgagaacc agctaaagct
     2401 gtcccacgac tggctgtgct atctggcccc tgagattgta cgcgagatga cccccgggaa
     2461 ggacgaggat cagctgccat tctccaaagc tgctgatgtc tatgcatttg ggactgtttg
     2521 gtatgagctg caagcaagag actggccctt gaagaaccag gctgcagagg catccatctg
     2581 gcagattgga agcggggaag gaatgaagcg tgtcctgact tctgtcagct tggggaagga
     2641 agtcagtgag atcctgtcgg cctgctgggc tttcgacctg caggagagac ccagcttcag
     2701 cctgctgatg gacatgctgg agaaacttcc caagctgaac cggcggctct cccaccctgg
     2761 acacttctgg aagtcagctg acattaacag cagcaaagtt gtaccccggt ttgaaaggtt
     2821 tggcttgggc gtcctggagt ccagtaatcc aaagatgtag ccagccatat ggtttttcgc
     2881 tgctgatctc tttcttttta aaatgtgttt ctgaaacatc ccaacaacca ccacgacaaa
     2941 aaaacactgc ctgcccagcg ctgcaaacca ggagcacacg tcctagattc agactgttgg
     3001 ccataaaccc cactcgggag atggagctgc acctgctatt tcttaaaatg acaccaccaa
     3061 caaccaaacc tgtcatgaca gacagcaaat gtttacacgt atatttctcc tgagtgaacc
     3121 tgatgtttta caataggtaa taataaaaac agtctgtgca gatgcactgg cactgacggc
     3181 caggatggcg gaaatggcca tcccctctga ggaccttgta ggcggtgagg gacccatgct
     3241 gggccagaag gaagacaaac atggtaattg cagctgttct tggggtaggg cggggagccc
     3301 agaaggtctg atctggcctc tgctttttgg cccaagactc catcagggaa atctatctag
     3361 ggctctcccc ttgtcctttc aaagggatac tgccccttcc tcgtcttgca gaggaaaccc
     3421 tggctaggaa ctgagctagt ttatggagtc tggaattcct ggagagcttg ggttcacctt
     3481 ctcacccctg taatccaggc tgctcctgct ggaaaagtag aaacagaatc caaaaaaggt
     3541 ctggactcac ccggtggttc ccagccaggg tttctgctgc aaggtgagga aacatccatg
     3601 gcttgtacag atgtgagtct ttgatgaagc ccccaggcag gcaccaaggt gatgggactc
     3661 agggccttgg cttttagata catcccagtc cctgactgac atctgaccat gagggctgga
     3721 tgggtgggaa caaggaggag tagatggcaa aagtacctga gcccacttcc cagccacagg
     3781 gtgaccctgg cactgtaaaa accctttgtc agtcatgcca gaaggttcta gaactgccca
     3841 cctcttccat ttcagtcctg ctgaaacccc ttagcctatt tccgactcct ctgtccatgc
     3901 tctgagttca gctgggcagt gtgtgggcta tcaccccttt catttagacc tacctagctg
     3961 gcccccatct gcagagcctt ccttagcacc attaggcctt ctacttgtgt ccatttgaag
     4021 caggaggggc tggatttgga aaagtctttg aagtgagagc accacgcttg tcttcgttag
     4081 aaactcttaa ctgcagaaaa aagttccaga tggcaaggga gcccttaagt ggagattagg
     4141 ttgcattaga ctccaaaacc agaaaggaaa aagggtgatg ggagtggaga cgtgattgga
     4201 ttcaggccca gaacctgtga ccatgctctg agctcagact tggggaggga ggggtgtggc
     4261 tcccacccct tccagttaag acctgcctag cagagcccca gtctccagcc ccttccctag
     4321 caccagagtc tggtcaaaat gccacagaaa atgagctgct ctgccagcaa gctgtggagc
     4381 tgcctcctct ccaggcctgg catcccttgg tcagcccctc ctgggagggc acagccgtat
     4441 tacagtgcca gtgtgcctgg ccatcagcat cttcaccctt cccagtctgt gtggggaggc
     4501 tgtaaacccc gtggattcag ctccgtgtgg agtttctgtg ctatggtggg actgctcatt
     4561 ttgccccatc atccctttgg cctcccacac acctgcccct tcccagggat cacgtgtgtc
     4621 tccagccttt cacctttcta ttgcaatggt ggcctttgtc caggcaagag caggcctgat
     4681 ggatgtactg gtgagcccca cagttggatg tcagctcagc cgtccaactg ggaggaacag
     4741 taggctcagt tcctccctga cccctgacac caggccgcag tgggcatgca caggcccaca
     4801 gaaagtcagt ctgggttttg cttttctcgt gagcatcaca gttaaagaag cgctcattga
     4861 gcaactacag tgcacttggt cttctgcaag tgctgggcac ctagagatag gaacagtcat
     4921 ggtccctgct cttaaggaac tgatgacctg gtggggccct gttgtcttca aggaacccag
     4981 aagccactgg gccccaaagg tggaactgaa ggactggggg cagctggctc tcagcctgcc
     5041 acctctgcac tgcctgcctt taaagaaccc caccccaccc catgatggcc ccctctgttc
     5101 cccttgtatt tcagtgactg tgaattgagg ttaggaaggc acacctgccc ttctgtgtgc
     5161 tctctccaca cgaaggatga cagatactgt gaattcagcc ctcacggcca actgtgaagg
     5221 ggatggagaa ggctgggagg gctcggggag agctcttagg ggctgcggaa gtccccacgg
     5281 gggtctgaga gtggagccca agctttggcc ctccaggcat ccccagtttc cagcctcacc
     5341 tctgaagccc tgctgccttt aaccaccaga gccgcagccc cctgggtttc tgtctaactc
     5401 gaagtcttga atcctagcta gtttggggtt gtgagcagtg tgtagcaaag ttgatctctc
     5461 catgtcacca aatcaaaaca ccctctgtca tcctacggca tttcctcttg aggtcacaga
     5521 gaggaatggc aagccctgga aacctgtgtt attctgtgtt gatttggtgt ggggggaggg
     5581 tggagacgta aatgtgaagc cagttggagt ttgtgctatg cagcagtgtt agccaggatc
     5641 tcatcagcgt gcaaacctag catcttctgt ggccacaagc cacacacttg ctttttttga
     5701 atgtgatgta aaatttgtac agtaaagttt ttatattttc tatcaactac atttgtcttc
     5761 cagacatgct attaatttaa attaaaatgg ttagtattaa caaacatgct gtatcgggtt
     5821 tttttgccac tggcaagaac atgccctctg tgctaagcca ggcctgggtg tctggagttt
     5881 gtgaataaag ttataccaag gtg
//
