LOCUS       NM_031963               1006 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens keratin associated protein 9-8 (KRTAP9-8), mRNA.
ACCESSION   NM_031963 XM_001127218 XM_003846482 XM_005276621 XM_005277795
            XM_006726315 XM_006726316 XM_006726742 XM_011508763 XM_011547136
            XM_017030241
VERSION     NM_031963.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1006)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S.,
            Korn,B. and Schweizer,J.
  TITLE     Characterization of a cluster of human high/ultrahigh sulfur
            keratin-associated protein genes embedded in the type I keratin
            gene domain on chromosome 17q12-21
  JOURNAL   J Biol Chem 276 (22), 19440-19451 (2001)
   PUBMED   11279113
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Michael Rogers. The reference sequence was
            derived from AC006070.1.
            
            On or before May 17, 2019 this sequence version replaced
            XM_017030241.1, NM_031963.2.
            
            Summary: This protein is a member of the keratin-associated protein
            (KAP) family. The KAP proteins form a matrix of keratin
            intermediate filaments which contribute to the structure of hair
            fibers. KAP family members appear to have unique, family-specific
            amino- and carboxyl-terminal regions and are subdivided into three
            multi-gene families according to amino acid composition: the high
            sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs.
            This protein is a member of the ultrahigh sulfur KAP family and the
            gene is localized to a cluster of KAPs at 17q12-q21. [provided by
            RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC074981.2 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000254072.7/ ENSP00000254072.6
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                AC006070.1         69093-69111         c
            20-1006             AC006070.1         68106-69092         c
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.2"
     gene            1..1006
                     /gene="KRTAP9-8"
                     /gene_synonym="KAP9.8; KRTAP9.8"
                     /note="keratin associated protein 9-8"
                     /db_xref="GeneID:83901"
                     /db_xref="HGNC:HGNC:17231"
     exon            1..1006
                     /gene="KRTAP9-8"
                     /gene_synonym="KAP9.8; KRTAP9.8"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..533
                     /gene="KRTAP9-8"
                     /gene_synonym="KAP9.8; KRTAP9.8"
                     /note="ultrahigh sulfur keratin-associated protein 9.8"
                     /codon_start=1
                     /product="keratin-associated protein 9-8"
                     /protein_id="NP_114169.2"
                     /db_xref="CCDS:CCDS42334.1"
                     /db_xref="GeneID:83901"
                     /db_xref="HGNC:HGNC:17231"
                     /translation="MTHCCSPCCQPTCCRTTCWKPTTVTTCSSTPCCQPSCCVSSCCQ
                     PCCRPTCCQNTCCQPICVTSCCQPSCCSTPCCQPTCCGQTSCGSSCGQSSSCAPVYCR
                     RTCYHPTTVCLPGCLNQSCGSNCCQPCCRPACCETTCCRTTCFQPTCVSSCCQPSCC"
ORIGIN      
        1 agattctggg aaactcacct ctgaacagaa ctccaccctc tacccctgac accatgaccc
       61 actgttgttc cccttgctgt cagcctacgt gctgcaggac cacctgctgg aagcccacca
      121 ctgtgaccac ctgcagcagc acaccctgct gccagccctc ctgctgtgtg tccagctgct
      181 gccagccttg ctgccgccca acttgctgtc aaaacacctg ctgccagccc atctgtgtga
      241 ccagctgctg ccagccttcc tgctgcagca caccctgctg tcagcccacc tgctgtggcc
      301 aaaccagctg tgggtccagc tgtggtcaga gcagctcctg tgcacctgtg tactgcagaa
      361 gaacctgcta ccaccccacg actgtctgcc tgcctggttg cctaaaccag agctgtggct
      421 ccaactgctg ccagccctgc tgccgcccag cctgctgtga gaccacctgc tgcaggacca
      481 cttgcttcca gcccacctgt gtgtccagct gctgccagcc ttcttgctgc tgatcacgtt
      541 ccaagagaac caccatcctc acacaacaaa tttctgctca actgactcat cttttggggg
      601 actaatttaa tttgctgctg acagccacca tgctctcacc caaattttta tgaattctct
      661 acatgtttaa aatcttggaa atctgcttga gggagggcag aatacttcat cctgattctc
      721 tttttcctta caccttgtgg atcatgtgcc agcttcatct gttctcaagt ttgagtcatg
      781 gtctcagctt tgactctaaa gtcaagagct tcattccctg cttctaagga atttaggttt
      841 ctgcaactga tcgatgatct ttgcaatctt ttttttgttt tcaatatcct cctcatcgtt
      901 cttgtatcct tctttcttct tttcatgata aatttgtgtt gtgtccctgg tagcagaaat
      961 ccttacctat atgtttctga ataaattctg aaccatcctc atctca
//
