LOCUS       NM_181605                636 bp    mRNA    linear   PRI 03-MAY-2024
DEFINITION  Homo sapiens keratin associated protein 6-3 (KRTAP6-3), mRNA.
ACCESSION   NM_181605
VERSION     NM_181605.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 636)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S. and
            Schweizer,J.
  TITLE     Characterization of a first domain of human high glycine-tyrosine
            and high sulfur keratin-associated protein (KAP) genes on
            chromosome 21q22.1
  JOURNAL   J Biol Chem 277 (50), 48993-49002 (2002)
   PUBMED   12359730
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. This record has been curated by NCBI staff in
            collaboration with Michael Rogers. The reference sequence was
            derived from AP001069.1.
            
            [WARNING] On Aug 14, 2024 this sequence was replaced by
            NM_181605.5.
            
            On May 17, 2019 this sequence version replaced NM_181605.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB096951.1, BC118624.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000391624.1/ ENSP00000375482.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-616               AP001069.1         44411-45026
            617-636             AP001069.1         45027-45046
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.11"
     gene            1..636
                     /gene="KRTAP6-3"
                     /gene_synonym="KAP6.3"
                     /note="keratin associated protein 6-3"
                     /db_xref="GeneID:337968"
                     /db_xref="HGNC:HGNC:18933"
     exon            1..636
                     /gene="KRTAP6-3"
                     /gene_synonym="KAP6.3"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..339
                     /gene="KRTAP6-3"
                     /gene_synonym="KAP6.3"
                     /codon_start=1
                     /product="keratin-associated protein 6-3"
                     /protein_id="NP_853636.3"
                     /db_xref="CCDS:CCDS77622.1"
                     /db_xref="GeneID:337968"
                     /db_xref="HGNC:HGNC:18933"
                     /translation="MTSTTNTMCGSYYRNYNGGHGYGCCGYGGLGCGYGGCGYGCCGY
                     GGLGFGYGGLDCGYGGLGCGYGSFCGCGYRGLDCGYGCGYGYVSHSFCGCGYRCGSGY
                     GSSFGYYY"
ORIGIN      
        1 ccaaggatga cctcaacaac caacaccatg tgtggcagct actacagaaa ctacaatggt
       61 ggccatggct atgggtgctg tggctacgga ggcctgggct gtggttatgg cggctgtggc
      121 tatgggtgct gtggctacgg aggcctgggc tttggctatg gaggcctgga ctgtggctat
      181 ggaggcctgg gctgtggcta tggctccttc tgtggctgtg gctacagagg cctggactgt
      241 ggctatggct gtggctatgg ctatgtctcc cactccttct gtggctgtgg ctataggtgc
      301 ggctctggct atggctccag ctttggctac tactattgag gacaccatgg gagactctca
      361 ccctctatcc tgtgacattg caattcacca attctgaagc ccacatgctc tgagcctttc
      421 ccttgattga tgatatcctg cagtggaagt ctaatatgat ctgttgttga tctaccatct
      481 aacccaaaaa taccctgagt ttccatcatg aagtgggata aggtgaagtt cacctgtcac
      541 ttctcctttt atcaggatga tggtgtcaca gtgactcctt tgatgacttt catgctgtag
      601 tttgtttctc tgctgaccta ataaacacat ttaatc
//
