LOCUS       NM_181602                500 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens keratin associated protein 6-1 (KRTAP6-1), mRNA.
ACCESSION   NM_181602
VERSION     NM_181602.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 500)
  AUTHORS   Rechiche,O., Plowman,J.E., Harland,D.P., Lee,T.V. and Lott,J.S.
  TITLE     Expression and purification of high sulfur and high
            glycine-tyrosine keratin-associated proteins (KAPs) for biochemical
            and biophysical characterization
  JOURNAL   Protein Expr Purif 146, 34-44 (2018)
   PUBMED   29391282
  REMARK    GeneRIF: Expressed and purified are a high sulfur KAP (KAP11.1) and
            a high glycine-tyrosine KAP (KAP6.1).
REFERENCE   3  (bases 1 to 500)
  AUTHORS   Hu,Y.H., Warnatz,H.J., Vanhecke,D., Wagner,F., Fiebitz,A.,
            Thamm,S., Kahlem,P., Lehrach,H., Yaspo,M.L. and Janitz,M.
  TITLE     Cell array-based intracellular localization screening reveals novel
            functional features of human chromosome 21 proteins
  JOURNAL   BMC Genomics 7, 155 (2006)
   PUBMED   16780588
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 500)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S. and
            Schweizer,J.
  TITLE     Characterization of a first domain of human high glycine-tyrosine
            and high sulfur keratin-associated protein (KAP) genes on
            chromosome 21q22.1
  JOURNAL   J Biol Chem 277 (50), 48993-49002 (2002)
   PUBMED   12359730
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. This record has been curated by NCBI staff in
            collaboration with Michael Rogers. The reference sequence was
            derived from AP001069.1.
            
            On Aug 12, 2021 this sequence version replaced NM_181602.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB096954.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000329122.2/ ENSP00000332690.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-500               AP001069.1         65402-65901         c
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.11"
     gene            1..500
                     /gene="KRTAP6-1"
                     /gene_synonym="C21orf103; KAP6.1"
                     /note="keratin associated protein 6-1"
                     /db_xref="GeneID:337966"
                     /db_xref="HGNC:HGNC:18931"
     exon            1..500
                     /gene="KRTAP6-1"
                     /gene_synonym="C21orf103; KAP6.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..242
                     /gene="KRTAP6-1"
                     /gene_synonym="C21orf103; KAP6.1"
                     /codon_start=1
                     /product="keratin-associated protein 6-1"
                     /protein_id="NP_853633.1"
                     /db_xref="CCDS:CCDS13602.1"
                     /db_xref="GeneID:337966"
                     /db_xref="HGNC:HGNC:18931"
                     /translation="MCGSYYGNYYGTPGYGFCGYGGLGYGYGGLGCGYGSCCGCGFRR
                     LGCGYGYGSRSLCGYGYGCGSGSGYYY"
ORIGIN      
        1 caaggacaac ctccacaacc aacaccatgt gtggcagcta ctacggaaac tactatggca
       61 cccctggcta tgggttctgt ggctatggag gcctgggcta tggctatgga ggcctgggct
      121 gtggctatgg ctcctgctgt ggctgtggct tccgcagact gggctgtggc tatggctatg
      181 gctcccgctc cctctgtggc tatggctatg gatgcggctc tggctctggc tactattatt
      241 gaggatgcca tgggagactc tcaccctcta tcctgtgata ctgagattca ctaattctga
      301 agcccacatg ttctgagatt ttcccttgag tgatgatatc ctgcaatgga agtctaatat
      361 ggtctgttgt tgagctacca tctaacctac aaatatcttg aatttccatc atgaaacggg
      421 ataaggtaaa attcacctgt cagttctcct ttcatcagaa tgatggtgtc acatcatctg
      481 ccttgatgac ttttatgatg
//
