LOCUS       NM_001012503            1403 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens keratin associated protein 5-7 (KRTAP5-7), mRNA.
ACCESSION   NM_001012503 XM_498520
VERSION     NM_001012503.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1403)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1403)
  AUTHORS   Yahagi,S., Shibuya,K., Obayashi,I., Masaki,H., Kurata,Y., Kudoh,J.
            and Shimizu,N.
  TITLE     Identification of two novel clusters of ultrahigh-sulfur
            keratin-associated protein genes on human chromosome 11
  JOURNAL   Biochem Biophys Res Commun 318 (3), 655-664 (2004)
   PUBMED   15144888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB126076.1 and AP000867.5.
            
            On May 17, 2019 this sequence version replaced NM_001012503.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB126076.1, BC136967.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000398536.6/ ENSP00000417330.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-898               AB126076.1         1-898
            899-1403            AP000867.5         56062-56566
FEATURES             Location/Qualifiers
     source          1..1403
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q13.4"
     gene            1..1403
                     /gene="KRTAP5-7"
                     /gene_synonym="KRTAP5-3; KRTAP5.7"
                     /note="keratin associated protein 5-7"
                     /db_xref="GeneID:440050"
                     /db_xref="HGNC:HGNC:23602"
     exon            1..1403
                     /gene="KRTAP5-7"
                     /gene_synonym="KRTAP5-3; KRTAP5.7"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..532
                     /gene="KRTAP5-7"
                     /gene_synonym="KRTAP5-3; KRTAP5.7"
                     /note="keratin-associated protein 5-3; keratin-associated
                     protein 5.3; keratin-associated protein 5.7; ultrahigh
                     sulfur keratin-associated protein 5.7"
                     /codon_start=1
                     /product="keratin-associated protein 5-7"
                     /protein_id="NP_001012521.1"
                     /db_xref="CCDS:CCDS41682.1"
                     /db_xref="GeneID:440050"
                     /db_xref="HGNC:HGNC:23602"
                     /translation="MGCCGCSEGCGSGCGGCGSGCGGCGSGCGGCGSSCCVPVCCCKP
                     VCCCVPACSCSSCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGCSQCSCYKPCC
                     CSSGCGSSCCQSSCCKPCCCQSSCCKPCCCSSGCGSSCCQSSCCNPCCSQSSCCVPVC
                     CQCKI"
     regulatory      953..958
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KRTAP5-7"
                     /gene_synonym="KRTAP5-3; KRTAP5.7"
                     /note="hexamer: AATAAA"
     polyA_site      981
                     /gene="KRTAP5-7"
                     /gene_synonym="KRTAP5-3; KRTAP5.7"
                     /note="major polyA site"
     regulatory      1383..1388
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KRTAP5-7"
                     /gene_synonym="KRTAP5-3; KRTAP5.7"
                     /note="hexamer: AATAAA"
     polyA_site      1403
                     /gene="KRTAP5-7"
                     /gene_synonym="KRTAP5-3; KRTAP5.7"
                     /note="major polyA site"
ORIGIN      
        1 cctctacctg ctccaccctc aatccaccag aaccatgggc tgctgtggct gttccgaagg
       61 ctgtggctcc ggctgtgggg gctgtggctc cggctgtggg ggctgtggct ctggctgtgg
      121 gggatgtggc tccagctgct gtgtgcccgt ctgctgctgc aagcccgtgt gctgctgtgt
      181 gccagcctgt tcctgctcca gctgtggctc ctgtgggggc tccaagggag gctgtggctc
      241 ctgtgggggc tccaaggggg gctgtggctc ttgtgggggt tctaaggggg gctgtggttc
      301 ttgtggctgc tcccagtgca gctgctataa gccctgctgc tgctcctcag gctgtgggtc
      361 atcctgctgc cagtccagct gctgtaagcc ctgctgctgc cagtccagct gctgtaagcc
      421 ctgctgctgt tcctcaggct gtgggtcatc ctgctgccag tccagttgct gcaatccctg
      481 ctgctcccag tctagctgct gtgtccccgt gtgctgccag tgtaagatct gaggctctgg
      541 actcaggtct catgtgagtc ctgctaaccc cattttccga agctgtgacc tgtccttcat
      601 cgttgagccc caaaccactg ctcagggtcc attcctcact ataagatgaa gccatatctg
      661 cctgcctttt cctaaggaga gtccacccta attaatgtcc attccctcct aacaaattct
      721 cttcccaagt caactgcaac tgcggctgaa tcacccctca cccgctagcc ttgcctttgc
      781 ttgtgtattc agaggcctga gctcctgaac ccacttgaag tcctgtcttt tccagctgga
      841 gcagctgggc atgagtgtcc cacctgcaac aaggtgggcg tttaagaggc ttccttggag
      901 tggctttgcc tgtccaacac tctgctttat cttaaatgaa aagttgcaaa ctaataaaaa
      961 taccatgccg acaaactgaa acacatatct tgctgatttc tctgttgttc ggggtcatta
     1021 ctatggctat ggctattgtt ttcttgttct tgttgtgttt cggactgcgt gggtctgatg
     1081 ctgatgttgc tggaaggtgc taggatgggg ctggctgtct cctctgcctc tcatctcctt
     1141 cctggctgac ccctcttttc tcagaacccc tctcttccta ggtctttcca gctattgatc
     1201 tgatggagac aggactgttc ctcaggccag ggccacagaa gcagaagagg ctgctgaaaa
     1261 ctctggggag ttcagacttg cctcctttcc ctggtccagg cctctgccat cttcctttgg
     1321 gaagtttttg taaccaactt actctgattg tctttgttgt tacacagcct gttgcctctg
     1381 taaataaaca ctcctagcac caa
//
